From fragmented to integrated: Advancing surface water quality assessment through WQPI in the upper Medjerda River, Northeastern Algeria by Benacherine Mostefa, Lyazid Mohamed Nadjib, Allaoua Noua, Soualah Alila Hana, Satour Abd El Latif, Chouiter Norhane, Debassi Bouchra, Zineb Chetouh, Md Galal Uddin

“…In this study, we evaluated the surface water quality of the upper Medjerda River in northeastern Algeria by integrating traditional indices, the Organic Pollution Index (OPI) and the Weighted Arithmetic Water Quality Index (WA_WQI), with advanced multivariate analyses including Principal Component Analysis (PCA) and Generalized Linear Models (GLMs). To overcome the limitations of conventional methods, we developed a new composite metric, the Water Quality Pollution Index (WQPI), synthesizing both general physicochemical conditions and organic pollution. …”
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Tocilizumab modulates the activity of the classical and alternative complement pathways in rheumatoid arthritis patients by Iván Ferraz-Amaro, Iván Ferraz-Amaro, Sergio Santos-Concepción, Javier Castro-Hernández, Maria Vanesa Hernández-Hernández, Beatriz Tejera Segura, Cristina Luna, Esmeralda Delgado-Frias, Federico Díaz-González, Federico Díaz-González, Federico Díaz-González

“…Multivariable linear mixed models were used to determine changes in the complement system cascades over time.ResultsAfter adjustment for disease activity, basal levels of the classical and alternative pathways decreased significantly after TCZ treatment. …”
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Systematic review on the application of 3D‐bioprinting technology in orthoregeneration: current achievements and open challenges by Rachel L. Pan, Kari Martyniak, Makan Karimzadeh, David G. Gelikman, Jonathan DeVries, Kelly Sutter, Melanie Coathup, Mehdi Razavi, Rajendra Sawh‐Martinez, Thomas J. Kean

“…Methods This review was performed using PubMed and Web of Science. …”
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Chronic diseases among University students: Prevalence, patterns and impact on health-related quality of life by Gazibara Tatjana, Pekmezović Tatjana, Popović Aleksandra, Paunić Mila, Kisić-Tepavčević Darija

“…The impact of chronic diseases on HRQoL was evaluated through series of linear regression models. Results. The prevalence of chronic diseases was 16.5%. …”
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Ticagrelor versus Clopidogrel in Patients with Severe Renal Insufficiency Undergoing PCI for Acute Coronary Syndrome by Yunxian Chen, Shaowen Tu, Zhixin Chen, Jue Xia, Baofeng Chen, Jinfeng Chen, Jiarong Liang, Xiangyang Liu, Liangqiu Tang

“…We used the adjusted Cox proportional hazards models to analyze the 1-year outcome endpoints, including the primary endpoint (the composite of cardiovascular death, recurrence of MI, or nonfatal ischemic stroke), death from any cause, and bleeding events (Bleeding Academic Research Consortium, BARC criteria). …”
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Association between pan-immune inflammatory value and all-cause mortality in critically ill patients with ischemic stroke: a retrospective analysis of the MIMIC-IV database (2008–2... by Anni Chen, Jiahui Wang, Qiaoying Huang, Zhizhou Hu, Donglan Jiang, Yunnan Hu, Liying Pan, Jianhui Chen, Xiaohong Hu

“…This study investigates the association between the pan-immune inflammatory value (PIV)—a composite biomarker derived from routine blood tests—and all-cause mortality (ACM) in critically ill ischemic stroke patients.MethodsWe extracted data from the MIMIC-IV (v3.0) database, identifying ischemic stroke patients using ICD-9/10 codes. …”
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Enhancing Orbital MRI Quality: Optimization of Saturation Pads for 1.5T by Sujitra Tinnut, Suwimon Nabumrung, Kornthip Jeephet, Kingkarn Aphiwatthanasumet

“…An experienced neuroradiologist, blinded to pad compositions, evaluated the images quantitatively and qualitatively. …”
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Pore Structure and Connectivity of Mixed Siliciclastic-Carbonate Tight Reservoirs in the Palaeogene from Qaidam Basin, NW China by Xin Wang, Jianhui Zeng, Kunyu Wu, Xiangcheng Gao, Yibo Qiu, Tongzhi Lu, Kunkun Jia, Chen Zhang, Juncheng Qiao, Zixin Xue, Qianyou Wang, Xiangye Kong

“…Mixed siliciclastic-carbonate rocks have complex compositions and heterogeneous spatial distributions of the various minerals. …”
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Personalized risk assessment of drug-related harm is associated with health outcomes. by Andrea A Jones, Fidel Vila-Rodriguez, William J Panenka, Olga Leonova, Verena Strehlau, Donna J Lang, Allen E Thornton, Hubert Wong, Alasdair M Barr, Ric M Procyshyn, Geoffrey N Smith, Tari Buchanan, Mel Krajden, Michael Krausz, Julio S Montaner, G William Macewan, David J Nutt, William G Honer

“…<h4>Methods</h4>A prospective community sample (n=293) of adults living in marginal housing was assessed for substance use. …”
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Recent Advances in Nanozymes for the Treatment of Atherosclerosis by Zou Z, Bi X, Ma H, Chen L, Jin H, Gong S, Li X, Liu X

“…This review comprehensively summarizes recent advances in nanozyme-based interventions for AS, focusing on representative systems such as Prussian blue, cerium oxide, selenium-based, and multifunctional composite nanozymes. We critically discuss their design principles, catalytic mechanisms, lesion-targeting strategies, and therapeutic outcomes in preclinical models. …”
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Evaluation of Internal Adaptation of Different CAD/CAM Endocrown Materials: A Comparative Microcomputed Tomography Study by Wala Saad, Abdul Rahman Saleh, Manal Almaslamani

“…Methods: Standardized endocrown restorations were fabricated for mandibular first molar models. …”
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The Impact of Open and Distance Learning (ODL) on Students' Psychological Well‐Being in Bangladesh: A Cross‐Sectional Study by Shahima Jabin

“…This study employed Structural Equation Modeling (SEM) to examine the construct relationships. …”
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Lead aVR predicts early revascularization but not long-term events in patients referred for stress electrocardiography. by Aparna Baheti, Christopher A Hanson, Michael McArdle, Sumeet K Lall, George A Beller, Jamieson M Bourque

“…We sought to determine the predictive value of lead aVR elevation for ischemia, early revascularization, and subsequent cardiac events in consecutive patients undergoing ExECG.<h4>Methods and results</h4>The study cohort included 641 subjects referred for ExECG who were dichotomized by presence or absence of aVR elevation ≥1mm and compared for prevalence and predictors of ischemia and a composite of cardiac death, nonfatal myocardial infarction, and late revascularization. …”
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Inverse association of oxidative balance score with depression and specific depressive symptoms among cancer population: Insights from the NHANES (2005-2020). by Hanli Bu, Mingzhen Lv, Linxian Wang, Dan Jiang, Yi Ding, Zheya Wang, Yaoyao Hu, Qin Zhuang, Zhenzhen Tian

“…<h4>Methods</h4>Data were analyzed from 3,280 adult cancer patients collected in NHANES from 2005-2020. …”
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Efficacy of wearable devices detecting pulmonary congestion in heart failure: a systematic review and meta-analysis by Cian P. Murray, Andrew P. Kenny, Niall J. O’Sullivan, Ross T. Murphy, James P. Curtain

“…This meta-analysis examines the efficacy of wearable devices in reducing HF hospitalizations and mortality compared to standard care.MethodsA systematic review and meta-analysis were conducted following PRISMA guidelines. …”
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Cardiovascular and Renal Outcomes with Ertugliflozin by Baseline Use of Renin-Angiotensin-Aldosterone System Inhibitors or Diuretics, Including Mineralocorticoid Receptor Antagonis... by David Z.I. Cherney, Robert Frederich, Richard E. Pratley, Francesco Cosentino, Samuel Dagogo-Jack, Annpey Pong, Ira Gantz, Nilo B. Cater, James P. Mancuso, Urszula Masiukiewicz, Christopher P. Cannon

“…There was no evidence of treatment effect on the kidney composite outcomes by baseline use of RAAS inhibitors, diuretics, loop diuretics, or MRAs.…”
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Efficacy of a Blended Low-Intensity Internet-Delivered Psychological Program in Patients With Multimorbidity in Primary Care: Randomized Controlled Trial by Alicia Monreal-Bartolomé, Adoración Castro, M Ángeles Pérez-Ara, Margalida Gili, Fermín Mayoral, María Magdalena Hurtado, Esperanza Varela Moreno, Cristina Botella, Azucena García-Palacios, Rosa M Baños, Yolanda López-Del-Hoyo, Javier García-Campayo, Jesus Montero-Marin

“…Differences between the groups were estimated using mixed effects linear regression models, and mediation evaluations were conducted using path analyses to evaluate the potential mechanistic role of positive and negative affectivity and openness to the future. …”
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Relationship Among Macronutrients, Dietary Components, and Objective Sleep Variables Measured by Smartphone Apps: Real-World Cross-Sectional Study by Jaehoon Seol, Masao Iwagami, Megane Christiane Tawylum Kayamare, Masashi Yanagisawa

“…Models were adjusted for age, sex, and BMI. …”
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Assessing Risk Factors and Posttransplant Outcomes of Nonadherence Among Kidney Transplant Recipients by Kateryna Maksyutynska, HBSc, Benedict Batoy, HBSc, Xinyu Wei, HBSc, Oswa Shafei, HBSc, Yanhong Li, MSc, Olusegun Famure, dipHSM, MPH, MEd, CHE, S. Joseph Kim, MD, PhD, MHS, MBA, FRCPC

“…Methods. A retrospective single-center cohort study was conducted among KTR transplanted from January 1, 2003, to December 31, 2017. …”
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Estimating complications and mortality in patients with post-surgical chronic hypoparathyroidism in England: A retrospective matched cohort study by Narendra L. Reddy, Caoimhe T. Rice, Sara J. Carvalho, Jennifer A. Davidson, Elizabeth Glenister, Christopher T. Sibley, Alden R. Smith, Wahidullah Noori

“…Regression models were adjusted for potential confounding variables where possible. …”
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