Alginate Sphere-Based Soft Actuators by Umme Salma Khanam, Hyeon Teak Jeong, Rahim Mutlu, Shazed Aziz

“…This review examines recent advances in alginate sphere-based actuators, focusing on fabrication methods such as droplet microfluidics, coaxial flow and functional surface patterning, and strategies for introducing multi-stimuli responsiveness using smart polymers, nanoparticles and biologically active components. …”
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Association between isolated abnormal 1-hour glucose challenge test and adverse pregnancy outcomes: a retrospective review from an urban tertiary care center in the United States by Hillary Hosier, Lisbet S. Lundsberg, Jennifer Culhane, Caitlin Partridge, Moeun Son

“…Bivariable analyses and multivariable logistic regression modeling were performed. Results Of 37,277 eligible patients, 29,698 (79.7%) had normal screening results, 5092 (13.7%) had intermediate screening results, and 2487 (6.6%) were diagnosed with GDM. …”
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Human papillomavirus vaccines: organisation and experience of preclinical studies by A. S. Korovkin, T. N. Nikitina, T. Yu. Kozlova, D. V. Gorenkov, A. R. Volgin

“…Preclinical study programmes may be supplemented with individual stages of comprehensive assessment of adjuvants and other additives included in novel HPV vaccine compositions.CONCLUSIONS. The authors have studied the international experience and presented a systemic overview of the methods and approaches used in preclinical studies of HPV vaccines. …”
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Optimisation of induction conditions for a bacterial strain producing proinsulin aspart by I. A. Kornakov, Z. R. Khasanshina, D. A. Senichkina, A. A. Filipenko, I. S. Lunev, R. V. Drai

“…The plotted models demonstrated high predictive power and high reproducibility of the results. …”
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Air pollution and cognitive performance in late life: the role of lipid profile – results from the Multi-Ethnic Study of Atherosclerosis (MESA) by Xi Pan, Robyn L. McClelland, Lilah M. Besser, Jana A. Hirsch, Joel D. Kaufman, Jing Cao, Timothy M. Hughes

“…Outdoor residential concentrations of PM2.5, NO2, and NOx between Exams 1 and 5 were assessed using validated spatiotemporal models. Total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) concentrations in blood at Exam 5 were evaluated as mediators or modifiers using linear regression models. …”
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Burden of Coronary Artery Disease as a Predictor of New Vascular Events and Mortality in Patients With Ischemic Stroke: Insights From the Norwegian Stroke in the Young Study by Khuluud Abdi Jibril, Kier Jan Kuiper, Beenish Nawaz, Halvor Naess, Annette Fromm, Halvor Øygarden, Kristin Modalsli Sand, Rudy Meijer, Abukar Mohamed Ali, Terje H. Larsen, Øyvind Bleie, Elisabeth Skaar, Ulrike Waje‐Andreassen, Sahrai Saeed

“…In the multivariable Cox regression models, CAD was a strong and independent predictor of all‐cause mortality (hazard ratio [HR], 2.20 [95% CI, 1.05–4.60]; P=0.037) and the composite end point of death or recurrent ischemic stroke (HR, 3.24 [95% CI, 1.46–7.20]; P=0.004). …”
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Advances and trends of non-marine shale sedimentology: A case study from Gulong Shale of Daqing Oilfield, Songliao Basin, NE China by Longde SUN, Rukai ZHU, Tianshu ZHANG, Yi CAI, Zihui FENG, Bin BAI, Hang JIANG, Bo WANG

“…Such research will focus on eight aspects: lithofacies and organic matter distribution prediction under a sequence stratigraphic framework for non-marine shale strata; lithofacies paleogeography of shale strata based on the forward modeling of sedimentation; origins of non-marine shale lamina and log-based identification of lamina combinations; source of organic matter in shale and its enrichment process; non-marine shale lithofacies classification by rigid particles + plastic components + pore-fracture system; multi-field coupling organic-inorganic interaction mechanism in shale diagenesis; new methods and intelligent core technology for shale reservoir multi-scale characterization; and quantitative evaluation and intelligent analysis system of shale reservoir heterogeneity.…”
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Antiplatelet Use Prior to Anticoagulant Initiation in Patients With Atrial Fibrillation-Related Ischemic Stroke: An ELAN Trial Analysis by Alexandros A. Polymeris, Masatoshi Koga, Daniel Strbian, Adhiyaman Vedamurthy, Manju Krishnan, Mattia Branca, Thomas Horvath, Martina Goeldlin, Gek Shim, Christoph Gumbinger, Liqun Zhang, Espen Saxhaug Kristoffersen, Philippe Desfontaines, Peter Vanacker, Angelika Alonso, Sven Poli, Ana Paiva Nunes, Nicoletta G. Caracciolo, Markus Kneihsl, Timo Kahles, Daria Giudici, Silja Räty, Marjaana Tiainen, Jesse Dawson, Urs Fischer, for the ELAN Investigators

“…Here, we explored the risks and benefits of this approach. Methods A post-hoc analysis of ELAN (Early versus Late Initiation of Direct Oral Anticoagulants in Post-ischemic Stroke Patients with Atrial Fibrillation) trial data (NCT03148457) was conducted to compare the risk of recurrent ischemic stroke, systemic embolism, major bleeding (extracranial or intracranial hemorrhage [ICH]), and vascular death within 30 days (as a composite and as individual outcomes) in participants treated with and without antiplatelets before DOAC initiation after an AF-associated ischemic stroke. …”
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Pain and Sleep Disturbances are Associated with Post-stroke Anger Proneness and Emotional Incontinence by Adekola B. Ademoyegun, Wasiu A. Rasaq, Omotola I. Adelowokan, Victor A. Afolabi, Adebukola G. Ibitoye, Taofeek O. Awotidebe, Chidozie E. Mbada

“…Data on potential confoundingvariables were also assessed.Results: The rates of PSSD, PSP, PSAP and PSEI among Nigerian stroke survivors were 36.8%, 63.3%, 23.2% and 44.9%, respectively.The results of logistic regression models showed that composite PSP was associated with PSEI (adjusted odd ratio (aOR): 0.492;95% confidence interval (CI): 0.251-0.965). …”
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Cardiovascular-kidney-metabolic comorbidities in colorectal cancer survivors: a nationwide cohort study on the role of metabolic syndrome by Xin Liu, Wenbo Zhao, Chang Zheng

“…In multivariable Cox models, MetS was independently associated with elevated CVD risk (HR = 1.36, 95% CI: 1.20–1.54). …”
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New Strategies Based on Hierarchical Matrices for Matrix Polynomial Evaluation in Exascale Computing Era by Luisa Carracciuolo, Valeria Mele

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Integrating GIS and remote sensing for soil attributes mapping in degraded pastures of the Brazilian Cerrado by Rômullo Oliveira Louzada, Ivan Bergier, Édson Luis Bolfe, Jayme Garcia Arnal Barbedo

“…Results showed that Boruta-enhanced models (T2 + T4) improved performance in 89 % of cases. …”
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DEUS Enthesitis Index (DEI): a new tool integrating ultrasound and clinical examination for enthesitis assessment in spondyloarthritis by Emilio Filippucci, Andrea Di Matteo, Stefano Di Donato

“…Objectives (1) To develop a composite score, the DEUS (Defining Enthesitis on Ultrasound in Spondyloarthritis) Enthesitis Index (DEI), which integrates ultrasound and clinical examination findings for enthesitis assessment in patients with spondyloarthritis (SpA); (2) to examine the relationships between DEI and clinical features in this population, compared to the clinical examination of the entheses alone.Methods This was a cross-sectional, observational, multicentric study involving 20 rheumatology centres across 11 countries. …”
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Influence of the crushed stone content on the deformation modulus of the soil-crushed stone layer by A. S. Prolygin, A. S. Aleksandrov, G. V. Dolgih, V. V. Chusov

“…The goal was achieved by performing stamp tests of the models of a road clothing and a roadbed.Materials and methods. …”
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Patients’ experience of care index: A new, reliable, and useful questionnaire in lumbar spine surgery by Arkan Sam Sayed Noor, Björn Knutsson

“…We employed linear regression, t-test, and ANOVA models to examine the associations between the PEC index and the documented variables. …”
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The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio as a predictor of all cause and cardiovascular mortality in United States adults with NAF... by Lisha Yang, Jingwen Li, Yilian Xie, Guoqing Qian

“…Multivariate Cox proportional hazards models and restricted cubic spline (RCS) methods were employed to assess all-cause and cardiovascular mortality. …”
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A comparison of ultrasonic detectors and radiotelemetry for studying bat–habitat relationships by Adam D. Morris, Darren A. Miller, L. Mike Conner

“…Therefore, during summer 2008, we examined use of bat detectors and radiotelemetry to infer habitat selection among 4 forest habitat types in southwestern Georgia, USA by simultaneously radiotracking evening bats (Nycticeius humeralis; n = 14) and using stratified sampling to acoustically monitor bat activity (n = 95 sites). We used compositional analysis for radiotelemetry data and generalized linear models for acoustic data to assess habitat selection at Johnson's (1980) 2nd and 3rd order spatial scales. …”
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Accelerating cell culture media development using Bayesian optimization-based iterative experimental design by Harini Narayanan, Joshua A. Hinckley, Rachel Barry, Brendan Dang, Lenna A. Wolffe, Adel Atari, Yuen-Yi Tseng, J. Christopher Love

“…We identified conditions with improved outcomes for both applications compared to the initial standard media using 3–30 times fewer experiments than that estimated for other methods such as the standard Design of Experiments. …”
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Genetic polymorphisms in SLC5A2 are associated with clinical outcomes and dapagliflozin response in heart failure patients by Ahmed Essam Abou Warda, Rylie M. Flohr, Rania M. Sarhan, Rania M. Sarhan, Mohamed Nabil Salem, Heba F. Salem, Heba F. Salem, Ayman N. Moharram, Abdullah S. Alanazi, Christelle Lteif, Brian E. Gawronski, Leanne Dumeny, Tariq G. Alsahli, Khaled Elenizi, Bassem Zarif, Neven Sarhan, Julio D. Duarte

“…Adjusted Cox proportional-hazard regression models were used to assess the effect of SLC5A2 variation on a primary composite outcome of cardiovascular (CV) hospitalization or all-cause mortality in SGLT2i-naïve patients, and HF hospitalization or CV death in dapagliflozin-treated patients. …”
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<i>In situ</i> Intranasal Delivery Systems: Application Prospects and Main Pharmaceutical Aspects of Development (Review) by E. O. Bakhrushina, N. B. Demina, M. M. Shumkova, P. S. Rodyuk, D. S. Shulikina, I. I. Krasnyuk

“…In vitro and ex vivo methods with mucosa and artificial nasal fluid are widely used to assess the parameters of in situ gelation, but to increase the reproducibility of the methods and improve the correlation in vitro/in vivo, it is recommended to conduct modeling of the nasal cavity. …”
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