A sustainable organizational structure to integrate psycho-social stimulation programme into primary health care services in Bangladesh: protocol for a pragmatic cluster randomized... by S. M. Mulk Uddin Tipu, Sheikh Jamal Hossain, Shams El Arifeen, Syeda Fardina Mehrin, Nur E Salveen, Masuma Kawsir, Mohammad Saiful Alam Bhuiyan, Shamima Shiraji, Mohammed Imrul Hasan, Fahmida Tofail, Jena Derakhshani Hamadani

“…We will follow a cascade training model to train personnel at all levels of the primary health care system. …”
Get full text

Association of C-reactive protein-triglyceride glucose index with the incidence and mortality of cardiovascular disease: a retrospective cohort study by Yu Sun, Yu Guo, Shiyin Ma, Zhi Mao, Deguo Meng, Kaige Xuan, Ruogu Lu, Xudong Pan, Xiaoyan Zhu

“…Abstract Background The C-reactive protein-triglyceride-glucose index (CTI) has emerged as an innovative composite marker for evaluating metabolic-inflammatory dysregulation, integrating markers of insulin resistance and systemic inflammation. …”
Get full text

Associations of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with diabetes and prediabetes among adults with hypertension: a cross-section... by Qing Meng, Qing Meng, Shengqiang Fan, Shengqiang Fan, Li Zhang, Bin Shen, Chaoping Zou, Dezhou Sun, Xianghui Liu, Jian Zhang, Shugang Xu

“…BackgroundThe non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is an emerging composite lipid marker. Prediabetes, characterized by an asymptomatic state with moderate hyperglycemia, is more prevalent than diabetes. …”
Get full text

The Association Between Neonatal Respiratory Distress Syndrome and Plasma IgG N-Glycosylation: A Case-Control Study by Wang Y, Shen Q, Yan R, Wang M, Xu M, Chen H, Li D

“…Furthermore, an increase in plasma IgG sialylation and core fucosylation was observed in NRDS, whereas the modification with galactosylation was decreased. The model constructed using GP1, GP13, GP14, PROM, and GGT as composite indices demonstrated robust predictive performance (AUC=0.902, 95% CI: 0.851– 0.953).Conclusion: Patients with NRDS frequently exhibit alterations in the glycosylation of plasma IgG. …”
Get full text

Two-Year Longitudinal Motor Performance of Very Preterm and/or Very-Low-Birth-Weight Infants in Suriname by Anjo J. W. M. Janssen, Maria J. A. J. Fleurkens-Peeters, Reinier P. Akkermans, Se-Sergio M. Baldew, Maria W. G. Nijhuis-van der Sanden, Wilco C. W. R. Zijlmans

“…Very preterm infants (gestational age < 32 weeks and/or very-low-birth-weight < 1500 g) in the middle-income country of Suriname were included. <b>Methods:</b> We assessed 149 (49.7% boys) infants (mean gestational age 29⁺⁶, mean birth weight 1271 g) at 3, 12, and 24 months with the Bayley Scales of Infant and Toddler Development for fine motor (FM), gross motor (GM), and composite scores (CSs). …”
Get full text

Comparison of ductus venosus Doppler and cerebroplacental ratio for the prediction of adverse perinatal outcome in high‐risk pregnancies before and after 34 weeks by José Morales‐Roselló, Rohan Bhate, Nashwa Eltaweel, Asma Khalil

“…Adverse perinatal outcome was defined as a composite of abnormal cardiotocogram, intrapartum pH requiring cesarean delivery, 5′ Apgar score <7, neonatal pH <7.10 and admission to neonatal intensive care unit. …”
Get full text

Suicidal ideation, attempt and associated factors among adult cancer patients at Jimma University Medical Center, Jimma, Ethiopia, 2023 by Kunuya Kunno, Asmare Belete, Tamrat Anbesaw, Monenus Teshome, Shimelis Girma Kassaye, Badiru Dawud, Zelalem Birhan

“…Suicidal ideation and attempts were assessed by the Composite International Diagnostic Interview Module. …”
Get full text

5-Item Modified Frailty Index Score is Associated with Increased Postoperative Complications Following Ankle Fracture ORIF by Ronit Kulkarni BS, Alexander S. Guareshi BS, Nikhil Vallabhaneni BA, Joshua L. Morningstar BS, Daniel J. Scott MBA, MD, Christopher E. Gross MD

“…It is essential to quantify preoperative risk for patients undergoing ankle fracture repair, but a consensus regarding an optimal risk stratification model does not currently exist. The 5-factor modified frailty index (mFI-5) has been found to be an independent predictor of postoperative complications following numerous orthopaedic procedures, but its efficacy has not been evaluated in patients undergoing ankle fracture open reduction and internal fixation (ORIF). …”
Get full text

Evaluative performance of TyG-ABSI versus traditional indices in relation to cardiovascular disease and mortality: evidence from the U.S. NHANES by Xin Zheng, Wenjing Zhang, Feng Yang, Leigang Wang, Bing Yu, Bin Liang

“…Further analyses, including competing risks models, E-value estimation, and RCS modeling, confirmed the robustness of these associations. …”
Get full text

A biomimetic multimodal nanoplatform combining neutrophil-coated two-dimensional metalloporphyrinic framework nanosheet and exendin-4 to treat obesity-related osteoporosis by Qifan Yang, Jing Liu, Yanwei Liu, Shun Liu, Xiaokang Wei, Yilin Yang, Weijie Zhang, Shuqi Zhang, Maosheng Zhang, Bin Liu, Xinyu Wang, Dong Zhu

“…The safety and efficacy of this nano-delivery platform were validated in a mouse model of obesity-induced osteoporosis. Conclusions: In summary, our study illustrates that excessive mitophagy plays a crucial role in obesity-induced osteoporosis. …”
Get full text

Rationale and Design of the ORCCA (Outcomes Registry for Cardiac Conditions in Athletes) Study by Nathaniel Moulson, Bradley J. Petek, Michael J. Ackerman, Timothy W. Churchill, Sharlene M. Day, Jonathan H. Kim, Stephanie A. Kliethermes, Rachel Lampert, Benjamin D. Levine, Matthew W. Martinez, Manesh R. Patel, Dermot Phelan, Kimberly G. Harmon, Aaron L. Baggish, Jonathan A. Drezner

“…Recent guidelines have taken a more permissive approach, using a shared decision‐making model. However, the impact and outcomes of this strategy remain unknown. …”
Get full text

Retinopathy, Neuropathy, and Subsequent Cardiovascular Events in Patients with Type 2 Diabetes and Acute Coronary Syndrome in the ELIXA: The Importance of Disease Duration by Jelena P. Seferovic, Rhonda Bentley-Lewis, Brian Claggett, Rafael Diaz, Hertzel C. Gerstein, Lars V. Køber, Francesca C. Lawson, Eldrin F. Lewis, Aldo P. Maggioni, John J. V. McMurray, Jeffrey L. Probstfield, Matthew C. Riddle, Scott D. Solomon, Jean-Claude Tardif, Marc A. Pfeffer

“…Proportional hazards regression models were used to assess relationships between retinopathy, neuropathy, and recurrent CV events. …”
Get full text

Multivariable Analysis of Primary Care Physician Adherence to Guideline-recommended Pharmacotherapy of Stable Coronary Artery Disease by S. K. Zyryanov, S. B. Fitilev, A. V. Vozzhaev, I. I. Shkrebniova

“…To study predictors of primary care physician adherence to guideline-recommended pharmacotherapy of stable coronary artery disease.Material and methods. This pharmacoepidemiologic cross-sectional study was conducted in primary care setting of Moscow. 805 patients (mean age 68.9±9.9 years, males 51.4%) with established stable coronary artery disease (SCAD) were included. …”
Get full text

Enhancing retention and quality of tissue stromal vascular fraction graft with globo H ceramide by Jing-Yan Cheng, Hui-Yun Cheng, Jung-Tung Hung, Gonzalo Mallarino Restrepo, Shih-Pin Chiou, Ling-Yi Shih, Alice L. Yu, Huang-Kai Kao, John Yu, Fu-Chan Wei

Get full text

Dynamic Lipid–Glycaemic Index and Inflammation—Endothelial Shifts and Fetal Aortic Wall Thickening: A Repeated-Measures Gestational Phenotyping Study by Maria Cezara Muresan, Biliana Belovan, Ioan Sîrbu, Zoran Laurentiu Popa, Cosmin Citu, Ioan Sas, Adrian Ratiu

“…Linear mixed-effects models and extreme-gradient-boosting quantified associations and predictive performance. …”
Get full text

Prognostic Impact of Anemia in Patients with Significant Mitral Regurgitation: A Multicenter Cohort Study by Lv J, Lu Q, Li Z, Ye Y, Zhang B, Wang W, Zhao Q, Zhang H, Zhao Z, Wang B, Liu Q, Guo S, Yu Z, Duan Z, Zhao Y, Gao R, Xu H, Ge J, Wu Y

“…This study sought to investigate the prevalence of anemia in patients with significant mitral regurgitation (MR), as well as its association with outcomes.Methods: A total of 4339 patients with moderate or greater MR in the China Valvular Heart Disease study were included in this analysis. …”
Get full text

Association of habitual glucosamine use with risk of microvascular complications among individuals with type 2 diabetes: a prospective cohort study in UK biobank by Zi-Jian Cheng, Yu-feng Luo, Qing-yun Zhu, Yan-fei Wang, Wen-yan Ren, Fei-yan Deng, Lin Bo, Xi-Yuan Jiang, Shu-feng Lei, Long-Fei Wu

“…Glucosamine use was significantly associated with lower risks of composite microvascular complications (hazard ratio (HR) 0.89, 95% CI: 0.81 to 0.97) and diabetic nephropathy (HR 0.87, 95% CI: 0.76 to 0.98) in fully adjusted models. …”
Get full text

Detecting the footprint of selection on the genome of Girgentana goat, a popular ancient breed by A. Criscione, S. Ben Jemaa, G. Chessari, S. Riggio, S. Tumino, G. Cammilleri, A. Lastra, F. Carta, M.T. Sardina, B. Portolano, S. Bordonaro, A. Cesarani, S. Mastrangelo

“…Girgentana goats are an ancient breed with distinctive morphological, adaptive, and production traits, making this population an interesting model for studying the genetic architecture underlying these traits. …”
Get full text

Whole-Genome Resequencing to Identify Selection Signatures Associated with High Fertility in Lüliang Black Goat by Xu Wang, Zhenqi Zhou, Xinrui Chai, Jie Li, Wannian Wang, Zhixu Pang, Lifen Cheng, Caihong Cheng, Liying Qiao, Yangyang Pan, Kaijie Yang, Wenzhong Liu, Jianhua Liu

“…Three selection signal analysis methods—Fst (Fixation Index), π (nucleotide diversity), and XP-CLR (Cross Population Composite Likelihood Ratio)—were applied to screen a total of 838 genes, and enrichment analysis was performed to identify genes closely related to the reproductive performance of LBG, including <i>ENPP3</i>, <i>APC</i>, and <i>GLI2</i>. …”
Get full text

Maternal exposure to air pollution and the risk of small for gestational age in offspring: A population-based study in Taiwan by Chien-Yu Huang, Chia-Lin Liu, Mei-Huei Chen, Po-Nien Tsao, Chien-Yi Chen, Hung-Chieh Chou, Pau-Chung Chen

“…The aim of this study is to investigate the effect of maternal exposure to criteria air pollutants and the lead in total suspended particulate matter during pregnancy on SGA births in Taiwan. Methods: This population study consisted of 322,513 singleton live births in Taiwan between 1996 and 2002. …”
Get full text