Prepregnancy Obesity Reprograms Offspring Skeletal Muscle Fibre Transition Through H3K9me3 by Yichi Wu, Sujuan Li, Jingyi Zhang, Anran Tian, Xiangyao Wang, Xi Yang, Fucheng Meng, Qing Li, Yuan Gao, Yingying Li, Furong Liang, Minglan Yao, Xiaoping Luo, Cai Zhang

“…Given that skeletal muscle plays a crucial role in systemic metabolism, we investigated how maternal prepregnancy high‐fat diet (HFD) influences muscle fibre composition and metabolic function in offspring. Methods We established mouse models with a prepregnancy chow diet (CD) and a prepregnancy high‐fat diet (HFD) for 8 weeks to compare metabolic phenotypes in offspring. …”
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Microbial Patterns in Newly Diagnosed Inflammatory Bowel Disease Revealed by Presence and Transcriptional Activity - Relationship to Diagnosis and Outcome by Vatn SS, Hansen SH, Tannæs TM, Brackmann S, Olbjørn C, Bergemalm D, Keita ÅV, Gomollon F, Detlie TE, Kalla R, Satsangi J, Jahnsen J, Vatn MH, Halfvarson J, Hov JR, Ricanek P, Moen AEF

“…Simen Svendsen Vatn,1– 3,* Simen Hyll Hansen,1,4,* Tone Møller Tannæs,5 Stephan Brackmann,1,2 Christine Olbjørn,1,6 Daniel Bergemalm,7 Åsa V Keita,8 Fernando Gomollon,9 Trond Espen Detlie,1,2 Rahul Kalla,10 Jack Satsangi,10,11 Jørgen Jahnsen,1,2 Morten Harald Vatn,1 Jonas Halfvarson,7 Johannes Roksund Hov,1,4,12 Petr Ricanek,2,13 Aina EF Moen1,5,14 On behalf of the IBD-Character Consortium1Institute of Clinical Medicine, University of Oslo, Oslo, Norway; 2Department of Gastroenterology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway; 3Innlandet Hospital Trust, Gjøvik, Norway; 4Norwegian PSC Research Center and Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway; 5Section for Clinical Molecular Biology (Epigen), Akershus University Hospital, Lørenskog, Norway; 6Department of Pediatric and Adolescent Medicine, Akershus University Hospital, Lørenskog, Norway; 7Department of Gastroenterology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden; 8Department of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden; 9Digestive Diseases Unit, IIS Aragón, Zaragoza, Spain; 10Gastrointestinal Unit, Centre for Genomics and Molecular Medicine, Division of Medical and Radiological Sciences, University of Edinburgh, Edinburgh, UK; 11Translational Gastroenterology Unit, Medical Sciences/ Experimental Medicine Division, University of Oxford, Oxford, UK; 12Section of Gastroenterology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway; 13Department of Gastroenterology, lovisenberg Diaconal Hospital, Oslo, Norway; 14Department of Virology, Norwegian Institute of Public Health, Oslo, Norway*These authors contributed equally to this workCorrespondence: Simen Svendsen Vatn, Innlandet Hospital Trust, Gjøvik, Norway, Tel +47 94277594, Email bikkjas@hotmail.comBackground: As part of the IBD Character initiative, we examined an inception cohort and investigated mucosal microbiota composition and transcriptional activity in relation to clinical outcomes.Methods: A cohort of 237 individuals were included from five countries: Crohn’s disease (CD, n = 72), ulcerative colitis (UC, n = 57), symptomatic non-IBD controls (SC, n = 78) and healthy controls (HC, n = 30). …”
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Customised production of injection moulded parts from recycled materials using rapid tooling approach and coupled injection moulding-thermal and mechanical simulation by Szabolcs Krizsma, András Suplicz, Dániel Gere

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Remote sensing image semantic segmentation network based on multi-scale feature enhancement fusion by Feiting Wang, Yuan Zhang, Qiongqiong Hu, Yu Zhu

“…Semantic segmentation is a crucial method for recognizing and classifying objects in high-resolution remote sensing images (HRRSIs). …”
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Risk of portal hypertensive complications preventable by TIPS in patients with ascites by Lorenz Balcar, Marta Tonon, Joan Valls, Valeria Calvino, Lucie Simonis, Jan Embacher, Roberta Gagliardi, Christian Sebesta, Leonie Hafner, Antonio Accetta, Lukas Hartl, Mattias Mandorfer, Michael Trauner, Paolo Angeli, Thomas Reiberger, Juan Carlos García-Pagán, Georg Semmler, Salvatore Piano

“…A model including ascites grade, sodium, and MELD accurately predicted the occurrence of this composite endpoint (area under the receiver operator characteristics curve: 0.79 [95% CI: 0.75–0.84]). …”
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Research on the Deformation Law of Jointed Surrounding Rock during Tunnel Excavation Based on Hydromechanical Coupling by Yan Wang, Mingfei Li

“…A finite element-based composite joint network modeling method is proposed in this paper, and the typical parameters of the surrounding rock, such as the plastic zone size, vertical displacement, and lateral displacement, are analyzed and compared through numerical calculations. …”
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TUH-NAS: A Triple-Unit NAS Network for Hyperspectral Image Classification by Feng Chen, Baishun Su, Zongpu Jia

“…We designed a new hyperspectral image attention mechanism module to increase the focus on critical regions and enhance sensitivity to priority areas. We also adopted a composite loss function to enhance the model’s focus on hard-to-classify samples. …”
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Video-based Intervention to Reduce Treatment and Outcome Disparities in Adults Living with Stroke or Transient Ischemic Attack (VIRTUAL): protocol for a randomized controlled trial by Munachi Okpala, Chigozirim Izeogu, Mengxi Wang, Charles Green, Gabretta Cooksey, Thuy Nguyen, Sarah Cohen, Latonya Bryant, Daphne C. Hernandez, Elmer V. Bernstam, Michael Gonzales, Rhonda Conyers, Olasimbo Chiadika, Kristin Varacalli, Sean I. Savitz, Jose-Miguel Yamal, Anjail Z. Sharrief

“…We designed a randomized comparative effectiveness trial to evaluate the Video-based Intervention to Reduce Treatment and Outcome Disparities in Adults Living with Stroke or Transient Ischemic Attack (VIRTUAL) model of care for post-stroke BP reduction. Methods The study will enroll 534 stroke survivors in a randomized trial to receive either the VIRTUAL intervention or enhanced standard care. …”
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Psychometric properties of the Feeling of Unsafety Scale—Arabic in general population adults by Sahar Obeid, Zeinab Bitar, Diana Malaeb, Fouad Sakr, Mariam Dabbous, Souheil Hallit, Souheil Hallit, Souheil Hallit, Feten Fekih-Romdhane, Feten Fekih-Romdhane

“…The study aimed to translate the Feeling of Unsafety Scale into Arabic (FUSA) and evaluate its psychometric properties, including internal reliability, sex invariance, composite reliability, and correlation with a measure of intolerance of uncertainty.MethodsA total of 484 Arabic-speaking adults was recruited between March and April 2024. …”
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Association of triglyceride-glucose index and estimated glucose disposal rate with outcomes in patients with acute myocardial infarction: Cumulative effect and mediation analysis. by Yazhao Sun, Pei Sun, Dongsheng Liu

“…Logistic regression models and restricted cubic splines (RCS) were used to assess the association between TyG index, METS-IR, and the risk of MACCEs. …”
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Exosome-Loaded GelMA Hydrogel as a Cell-Free Therapeutic Strategy for Hypertrophic Scar Inhibition by Wang H, Gao X, Zhao Y, Sun S, Liu Y, Wang K

“…A rabbit ear HS model was established. Three skin defects on each ear were treated with GelMA hydrogel, Exos-GelMA hydrogel, or left untreated as a blank group. …”
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Mechanisms of organotropism in breast cancer and predicting metastasis to distant organs using deep learning by Meizhu Xiao, Zhijin Fu, Yanjiao Li, Min Zhang, Denan Zhang, Lei Liu, Qing Jin, Xiujie Chen, Hongbo Xie

“…A deep neural network (DNN) model was developed to analyze these complex datasets and identify key predictors of organ-specific metastasis. …”
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The Hausa 12-item short-form health survey (SF-12): Translation, cross-cultural adaptation and validation in mixed urban and rural Nigerian populations with chronic low back pain.... by Aminu Alhassan Ibrahim, Mukadas Oyeniran Akindele, Sokunbi Oluwaleke Ganiyu, Bashir Kaka, Bashir Bello Abdullahi, Surajo Kamilu Sulaiman, Francis Fatoye

“…The refined model demonstrated good fit and evidence of factorial invariance in three demographic groups (age, gender, and habitation). …”
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Associations between nighttime or weekend deliveries and adverse maternal, birth, and neonatal outcomes: secondary analysis of the MANGO study in western Kenya by Maneet K. Virk, Jenine Shafi, Pooja Maheria, Garoma Basha, Harold E. Kooreman, John Humphrey, James G. Carlucci, Audrey Chepkemoi, Caitlin Bernard, Megan S. McHenry, Beverly Musick, Caroline Kerich, Winnie Matelong, Constantin T. Yiannoutsos, Wycliffe Kosgei, Julia Songok, Kara Wools-Kaloustian, Edwin Were, Rena C. Patel

“…More than half of deliveries occurred during nighttime (6pm to 7am)/weekends (62.6%). In multivariate modeling, nighttime/weekend delivery was associated with a reduced risk of adverse composite maternal outcomes (adjusted risk ratio [aRR] 0.92, 95% confidence interval [CI]: 0.88, 0.96) and composite birth outcomes (aRR 0.92, 95% CI: 0.88, 0.96). …”
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Cardiac magnetic resonance left atrioventricular coupling index as a prognostic tool in hypertrophic cardiomyopathy by Jinyang Wen, Junhao Tu, Xinwei Tao, Yuanyuan Tang, Zhaoxia Yang, Ziyi Pan, Yi Luo, Chunlin Xiang, Dazhong Tang, Lu Huang, Liming Xia

“…Multivariable Cox regression models were built including significant clinical variables, LA ejection fraction (LAEF), LA volume index (LAVI), late gadolinium enhancement (LGE) extent and LACI. …”
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Right Ventricular Function Score by Echocardiography for Predicting Outcomes After Heart Transplantation by Wei Sun, Yuji Xie, Ye Zhu, Yun Yang, Xin Zhang, Nianguo Dong, Guohua Wang, Yuman Li, Jing Wang, Qing Lv, Mingxing Xie, Li Zhang

“…Moreover, incorporating the RVFS into the base clinical model significantly improved the C‐statistic of the prediction model (C‐statistic from 0.70 to 0.83, P<0.001). …”
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Finite element analysis to assess stress and deformation in bone with glass fiber-reinforced-poly-ether-ether-ketone, zirconia, and titanium implants by Syeda Amtul Haseeb, Anju S Kumar, M P Chaitra, K C Vinaya, Soumya Shivananda Gudal, Fathima Parveen Rahmam, Prashant Babaji

“…This study was done to evaluate stress and deformation in bone with glass fiber-reinforced (GFR)-PEEK, zirconia, and titanium implants. Materials and Methods: A geometric model of mandibular molar replaced with implant-supported crown was generated. …”
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Assessment of Tunnel Explosion Mitigation Techniques for Fire Scenarios Involving Hydrogen Tank Rupture by Volodymyr Shentsov, Luisa Giuliani, Wenqian Liu, Frank Markert

“…This paper outlines how coupled computational fluid dynamics–finite element method (CFD–FEM) simulations can evaluate these mitigation methods, and we discuss design considerations (e.g., optimising barrier placement and tunnel geometry) for enhanced safety. …”
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Iterative Signal Processing for Blind Code Phase Acquisition of CDMA 1x Signals for Radio Spectrum Monitoring by Ron Kerr, John Lodge

“…Simulation results provide performance estimates of the method with noise, Rayleigh fading, and co-channel interference.…”
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Structural dynamic response synthesis: A transformer-based time-series GAN approach by Sayed Ali Khodaei, Maryam Bitaraf

“…The model integrates a transformer architecture with an attention mechanism to capture complex temporal dependencies and employs a composite loss function that aligns generated outputs with real signals in both time and frequency domains. …”
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