Manufacturing and impact resistance of Large-Scale stacked fibre metal laminates by Ding Tang, Haoyang Huang, Yitong Fan, Huamiao Wang, Yinghong Peng

“…This study introduces an automatic manufacturing process for large-scale stacked fibre metal laminates (FMLs) to reduce costs compared to traditional methods. A 3D finite element model was developed using Abaqus/Explicit, incorporating the Johnson─Cook, 3D-Hashin progressive damage, and cohesive surface models to evaluate the impact resistance of the produced FMLs. …”
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Economic TEHES-Tube Material Evaluation by Absorbability Index under O-S-Dimensions for Minimizing Global Warming and Air Pollution by Exploring Dominance Theory: Green Management... by M. Prabhu, Sri Yogi Kottala, A. Anbazhagan, Anoop Kumar Sahu

“…It is also probed that those models are simulated by single or nondynamic material evaluation methods. …”
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Effect of different restorative design on stress concentration of lithium disilicate and monolithic zirconia endocrown on a mandibular molar - a finite element analysis by Garima Karn, Manoj Shetty, Chethan Hegde

“…A uniform 2 mm of bulk fill composite was used as a base beneath the endocrowns. 300 N load was applied on the cusps for each model and linear static analysis was carried out. …”
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Regenerative potential of PRP-based scaffolds in chronic wound healing: Mechanisms, advances, and therapeutic insights by Farag M.A. Altalbawy, Bilal Abdul Majeed Mukhlif, Ahemad Hussen, Jaafaru Sani Mohammed, Renuka Jyothi S, Arshdeep Singh, Shakti Bedanta Mishra, Ashish Singh Chauhan, Mohammad Ebrahim Astaneh, Narges Fereydouni

“…Innovations such as GelMA/SFMA hydrogels and COL/PRP-ADSC-exos composites have shown superior outcomes in preclinical models. …”
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STUDY OF CHANGES IN OCCLUSAL SCHEME RESULTING FROM CREATING ARTIFICIAL TEETH IN THE DENTURE PATIENT WITH COMPLETE TOOTH LOSS AND ADVERSE CONDITIONS BY PROSTHETIC BED ON THE LOWER J... by V.P. Nespryadko, V.Y. Krasnov, V. K. Paul

“…In the control group metal overlay on artificial posterior teeth in prosthesis is not used, setting the teeth was carried out in semiajustable articulator Model 5000 (f. Bio - Art, Brazil) in lingvalized occlusion and also we used volumetric modeling for basis of mandibular complete denture. …”
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Release of Zinc, Manganese and Magnesium from Mg-Zn-Mn-Al-LDH: Effect of Malic Acid and Divalent to Trivalent Cation Ratios in Mineral Structure by Z. Movahedi Rad, M. Hamidpour

“…In this research, among the non-linear models used to determine the release kinetics of Zn, Mn, and Mg, the result with the highest R2 values was chosen. …”
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Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells by Xiaofei Wei, Lin Shen, Chang Liu, Cheng Zhang, Min Tao, Jian Li, Xicheng Wang, Ting He, Fei Dai, Changsong Qi, Mingyang Ma, Yanping Ding, Xinan Lu, Dongqun Liu

“…The underlying mechanism was further investigated based on mutation of the hinge and transmembrane domains.Results We found that the composition of the antigen-sensitive scFv, CD8α hinge, CD8α transmembrane, and CD28 costimulatory domains boosted CAR-T cells to rapidly kill tumors, maintain high expansion capacity, and long-term efficacy in various colorectal cancer models. …”
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Data-driven electrochemical behavior prediction for refractory high-entropy alloys by global and focused learning by Xinpeng Zhao, Haiyou Huang, Yanjing Su, Lijie Qiao, Yu Yan

“…In this work, we propose a data-driven method that integrates global and focused learning (GFL) strategies. …”
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A Deep Learning-Based Probabilistic Approach for Non-Destructive Testing of Aircraft Components Using Laser Ultrasonic Data by Adriano Liso, Cosimo Patruno, Angelo Cardellicchio, Pierfrancesco Ardino, Nicola Gallo, Giuseppe del Prete, Valerio Dentico, Veronica Vespini, Sara Coppola, Pietro Ferraro, Vito Reno

“…Here, we present a deep learning-based method for the non-destructive detection of defects in composite samples based on a laser ultrasonic system (LUT). …”
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The evolution of sprinting performance: Technological and regulatory influences from 1976 to 2024 by Dariusz Tadeusz SKALSKI, Magdalena PROŃCZUK, Kinga ŁOSIŃSKA, Ewelina LULIŃSKA, Joanna MOTOWIDŁO, Petr STASTNY, Adam MASZCZYK, Grzegorz TRYBEK

“…Understanding these factors is essential for assessing how sprint times have evolved and what future trends might emerge. Materials and methods: Utilizing a comprehensive dataset from international athletics federations, this research applies time series analysis, regression modeling, and variance testing to assess trends, gender disparities, and performance variability. …”
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Gut microbiota remodeling exacerbates neuroinflammation and cognitive dysfunction via the microbiota-gut-brain axis in prenatal VPA-exposed C57BL/6 mice offspring by Zhaoming Liu, Zhaoming Liu, Caixia Wu, Caixia Wu, Zhaojian Sun, Zuoxian Lin, Yirong Sun, Nouman Amjad, Muhammad Majid, Rajesh Basnet, Zhiyuan Li, Zhiyuan Li, Zhiyuan Li

“…Emerging evidence implicates the microbiota-gut-brain axis as a critical mediator of neuroinflammation and cognitive deficits, but causal pathways in VPA-induced ASD models require systematic exploration. This study investigates how prenatal VPA exposure reshapes gut microbiota composition, exacerbates neuroinflammatory responses, and drives cognitive dysfunction through the microbiota-gut-brain axis in C57BL/6 mouse offspring.MethodsPrenatal VPA-exposed and control offspring underwent behavioral assessments (open field, three-chamber social interaction, marble-burying, and Morris water maze tests). …”
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Curcumin supplementation accelerates high-altitude acclimatization, prevents polycythemia and modulates gut microbiota in male Han population: a randomized controlled trial by Jilei Hu, Hongmei Lang, Die Fan, Ting Wen, Jiaojiao Shi, Chunxiu Xiao, Yunming Li, Chao Kang, Peijie Shi, Peijie Shi, Lirong Shen, Ning Lin, Ning Lin, Ning Lin

“…BackgroundPrevious evidence showed that curcumin enhanced the oxygen supply efficiency of hemoglobin and alleviated acute plateau hypoxia injury in animal models. However, its efficacy on human beings is not yet verified. …”
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Multi-omics integration reveals the impact of mediterranean diet on hepatic metabolism and gut microbiota in mice with metabolic dysfunction-associated steatotic liver disease by Zixuan Wang, Zixuan Wang, Ge Chen, Xutong Sun, Jia Xiao, Lingling Kong, Shunshun Jiang, Tingting Xu, Meijiao Wang, Meijiao Wang, Hong Zhao

“…Post-modeling, MASLD mice were randomized into three groups: HF (continued high-fat diet), HF-NC (switched to normal chow), and HF-MD (switched to MD). …”
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Intranasal Transplantation of Microbiota Derived from Parkinson’s Disease Mice Induced Astrocyte Activation and Neurodegenerative Pathology from Nose to Brain by Yi-Meng Xia, Mei-Xuan Zhang, Xiao-Yu Ma, Lu-Lu Tan, Ting Li, Jian Wu, Ming-An Li, Wei-Jiang Zhao, Chen-Meng Qiao, Xue-Bing Jia, Yan-Qin Shen, Chun Cui

“…However relative studies are rare. Methods: By consecutive 14-days intranasally transplanting bacteria, we established mice models exhibiting nasal microbiota dysbiosis (NMD), including animal group received intranasal drops of fecal bacterial suspension from normal mice (NB group) and animal group received intranasal drops of fecal bacterial suspension from PD mice (PB group), with animals that only received anesthesia used as the control group. …”
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Unlocking the therapeutic potential of Pelargonium sidoides natural extract: A scoping review by Bárbara Donadon Reina, Samuel Santana Malheiros, Sâmmea Martins Vieira, Paula Ferreira de Andrade, Lívia Nordi Dovigo

“…Nonetheless, the establishment of a concentration protocol to further studies is still challenging due to variations in extract origin, composition and extraction methods. In this sense, the use of a commercial extract such as EPs® 7630 is of great value to facilitate the standardization of the tested protocols. …”
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Obesity-fertility cohort study: protocol for the assessment of children aged 6–12 years and their mothers by Marie-Eve Mathieu, Jean-Patrice Baillargeon, Patrice Perron, Anne-Sophie Morisset, Farrah Jean-Denis, Frederic Dallaire, Alexandra Thibodeau, Soren Harnois-Leblanc, Martin Brochu

“…This manuscript details the study protocol.Methods and analysis This is an ancillary nested cohort study of the obesity-fertility RCT. …”
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Heat Adaptation Benefits for Vulnerable groups In Africa (HABVIA): a study protocol for a controlled clinical heat adaptation trial by Michaela Deglon, Chad Africa, Larske Marit Soepnel, Thandi Kapwata, Ama de-Graft Aikins, Kweku Bedu-Addo, Guy Howard, Estelle Victoria Lambert, Dale Elizabeth Rae, Martha Sibanda, Christopher Gordon, Mark New, Lara Ruth Dugas

“…Quantitative comparisons will be made between intervention and control conditions using generalised linear mixed models. Qualitative data from consultive workshops will be used to assess the acceptability and feasibility of the adaptations. …”
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Evaluation of the Efficiency of a Soft Dosage Form for the Treatment of Osteoarthritis: Influence on the Level of Pro-inflammatory Cytokines by U. V. Nogaeva, V. E. Kovanskov, D. Yu. Ivkin, E. V. Flisyuk, K. D. Yakimov, E. I. Yeletskaya, E. D. Semivelichenko, V. G. Antonov

“…Preclinical modeling of the pathology was carried out by combined injection of 0.1 ml of a mixture of complete Freund's adjuvant with a 10 % suspension of talc in isotonic sodium chloride solution in a ratio of 1 : 10 into the cavity of the hock (tarsal) joint of Brown Norvay Catholic Rats male rats. …”
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Taurine alleviated paraquat-induced oxidative stress and gut-liver axis damage in weaned piglets by regulating the Nrf2/Keap1 and TLR4/NF-κB signaling pathways by Chen Chen, Min Qi, Weilong Zhang, Fanxing Chen, Zhihong Sun, Weizhong Sun, Wenjie Tang, Zhenguo Yang, Xuan Zhao, Zhiru Tang

“…Partial least squares path modeling and molecular docking were used to explore the intrinsic relationship between PQ, Tau, and the gut-liver axis. …”
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Success Factors of Growth-Stage Digital Health Companies: Systematic Literature Review by Estelle Pfitzer, Laura Bitomsky, Marcia Nißen, Christoph Kausch, Tobias Kowatsch

“…We categorized them into internal factor categories (Product and Services, Operations, Business Models, and Team Composition) and external factor categories (Customers, Health Care System, Government and Regulators, Investors and Shareholders, Suppliers and Partners, and Competitors). …”
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