Total and regional fat-to-muscle mass ratio and risks of pan-cancer: a prospective cohort study by Ruizhi Wang, Yudi Xu, Yuyuan Zhang, Yushuai Wu, Anning Zuo, Shutong Liu, Yuhao Ba, Hui Xu, Siyuan Weng, Zhaokai Zhou, Hongxuan Ma, Peng Luo, Quan Cheng, Xinwei Han, Zaoqu Liu

“…Multivariable Cox proportional hazards models, along with Cox models incorporating restricted cubic splines (RCS) function, were employed to examine both linear and non-linear associations between FMR and cancer risk in men and women. …”
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Modélisation géologique et estimation d’un gisement de Fer de Bekisopa, Madagascar by Rakotonirina M. D. L., Razakamanana T., Razafindrazanakolona A. D., Ramanampisoa V. E, Pius Tshimankinda Mpiana, Koto-Te-Nyiwa Ngbolua, Robijaona Rahelivololoniaina B.

“…L'évaluation des réserves de fer a été menée en appliquant des méthodes géostatistiques, notamment le krigeage. Les données issues des forages, conjointement avec les informations géologiques provenant des modèles tridimensionnels, ont servi à établir des variogrammes et des modèles de continuité spatiale. …”
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Evaluation of the recombinant protein Sh-TSP-2 for the serological diagnosis of imported urogenital schistosomiasis and comparison with commercially available tests by María Pilar Luzón-García, Laura Navarro, Esther Rodríguez, Manuel Jesús Soriano-Pérez, José Vázquez-Villegas, María Isabel Cabeza-Barrera, Alex Loukas, Nerea Castillo-Fernández, María Jesús Perteguer, Javier Sotillo, Joaquín Salas-Coronas

“…The Sh-TSP-2 urine and serum ELISA tests had the highest specificities among the serological methods (87.5 and 75%, respectively). CRS modelling showed that the ICT IgG–IgM, NovaLisa® and Sh-TSP-2 serum tests led in sensitivity at 97.1, 88.6 and 71.4%, respectively, with all tests except that the ICT IgG–IgM test having a specificity >90%. …”
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In-silico platform for the multifunctional design of 3D printed conductive components by Javier Crespo-Miguel, Sergio Lucarini, Sara Garzon-Hernandez, Angel Arias, Emilio Martínez-Pañeda, Daniel Garcia-Gonzalez

“…Abstract The effective electric resistivity of conductive thermoplastics manufactured by filament extrusion methods is determined by both the material constituents and the printing parameters. …”
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Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway by Yumei Rong, Yumei Rong, Yumei Rong, Yumei Rong, Yumei Rong, Minghui Zhu, Minghui Zhu, Minghui Zhu, Minghui Zhu, Nan Wang, Nan Wang, Nan Wang, Nan Wang, Feiyu Zhang, Feiyu Zhang, Feiyu Zhang, Feiyu Zhang, Tianjun Liu

“…IntroductionUlcerative colitis (UC) is an inflammatory bowel disease characterized by inflammation and ulceration of the digestive tract.MethodsPhotodynamic therapy (PDT) with a novel photosensitizer LD4 was used to treat UC rat models to explore the therapeutic effect and mechanism of LD4-PDT on UC. 16S ribosomal RNA was used to detect the composition of Gut microbiota.ResultsOur findings indicate that LD4-PDT could protect the integrity of the colonic mucosa, alleviate the inflammatory response and promote the healing of colonic mucosa. …”
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Machine learning prediction of obesity-associated gut microbiota: identifying Bifidobacterium pseudocatenulatum as a potential therapeutic target by Hao Wu, Yuan Li, Yuxuan Jiang, Xinran Li, Shenglan Wang, Changle Zhao, Changle Zhao, Ximiao Yang, Baocheng Chang, Juhong Yang, Juhong Yang, Jianjun Qiao, Jianjun Qiao

“…We assessed the anti-obesity effects of Bifidobacterium pseudocatenulatum through experimentation with Caenorhabditis elegans and C3H10T1/2 cells.ResultsOur analysis revealed a significant correlation between gut bacterial composition and body weight. The top 40 bacterial species were utilized to develop ML models, with XGBoost demonstrating the highest predictive accuracy. …”
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A BOX-YOLOv8 framework for automated hyperspectral core analysis by Hongyan Zhu, Anjie Li, Chengzhi Lin, Shuai Qin, Junhao Xie, Jackey J.K. Chai, Russell Rogers, Jun-Li Xu

“…This framework leverages a synergistic integration of deep learning models—specifically BOX-YOLOv8, SAM2, and a custom MLP—to achieve efficient, automated end-to-end processing. …”
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A systematic review on machine learning-aided design of engineered biochar for soil and water contaminant removal by Yunpeng Ge, Kaiyang Ying, Guo Yu, Muhammad Ubaid Ali, Abubakr M. Idris, Abubakr M. Idris, Asfandyar Shahab, Habib Ullah, Habib Ullah

“…The paper emphasizes how ML models—such as Random Forest (RF) and Gradient Boosting Regression (GBR)—elucidate the nonlinear links between pyrolysis conditions (temperature, feedstock composition) and biochar performance. …”
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Electroacupuncture modulates the gut-brain axis via the PI3K/Akt pathway to improve feeding behavior, body weight, glucolipid metabolism, and reduce insulin resistance in T2DM rats by Shaoyang Liu, Shuting Zhuang, Rui Li, Haoru Duan

“…The research aims to reveal the mechanisms underlying EA’s therapeutic effects and to investigate a novel strategy for managing T2DM. Methods To induce T2DM in rat models, a high-fat diet and intraperitoneal injection of streptozotocin (STZ) were used. …”
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Influence of cognitive, neuropsychiatric, and diagnostic factors on financial capacity: A longitudinal analysis of the ADNI cohort by Milap A. Nowrangi, Jeannie Marie Leoutsakos, Haijuan Yan, Arnold Bakker, Kevin J. Manning, George W. Rebok, Paul B. Rosenberg, Vidyulata Kamath

“…To investigate the relationship between FC, cognitive domains, neuropsychiatric symptoms, and transitions from normal cognition (cognitive normal [CN]) to mild cognitive impairment (MCI) or Alzheimer's disease (AD), we conducted a secondary analysis of the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort using the Financial Capacity Instrument short form (FCI‐SF). Methods To examine these longitudinal relationships, we fit two models, a random effects (random intercept) “time‐averaged” model and a “time since previous visit” model, where we regressed each of the five component financial scores on each of the cognitive composite scores. …”
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DCDGAN-STF: A Multiscale Deformable Convolution Distillation GAN for Remote Sensing Image Spatiotemporal Fusion by Yan Zhang, Rongbo Fan, PeiPei Duan, Jinfang Dong, Zhiyong Lei

“…These models treat STF as an image super-resolution problem based on multiple reference images. …”
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Confirmatory Factor Analysis of the Malay Version of the Malaysia Medication Adherence Assessment Tool (MyMAAT) Among Patients with Chronic Medications by Ong GT, Abdullah S, Bachok NB

“…There are two constructs in the MyMAAT, namely the Specific Medication-Taking Behaviour (Factor 1) and the Social-Cognitive Theory of Self-Efficacy and Social Support (Factor 2).Results: Four hundred and seventy participants participated in the CFA study. The final model for the Malay version of the MyMAAT retained the two constructs and 12 items with good fit: CFI = 0.978, TLI = 0.973, RMSEA = 0.036 (90% CI 0.001,0.067) and with good composite reliability CR 0.790 for Factor 1 and 0.787 for Factor 2. …”
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Association of ambient temperature and influenza-like illness with acute appendicitis: an ecological study using 22-year data by On Tai Ken Yu, Xiaoting Jiang, Conglu Li, Yawen Wang, Yuchen Wei, Ka Chun Chong

“…A generalized additive model under the framework of distributed-lag non-linear model and quasi-Poisson distribution was used for multivariate analysis. …”
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Multi-omics analysis reveals Lactobacillus and Indolelactic acid involved in small intestinal adaptation of piglet with short bowel syndrome by Weipeng Wang, Ying Lu, Bo Wu, Shicheng Peng, Wei Cai, Yongtao Xiao

“…This study utilized multi-omics analysis to investigate alterations in gut microbiota, metabolism, and transcriptome during the progression of intestinal adaptation in SBS using a piglet model. Methods We established a model of SBS in Bama mini piglets by performing a 75% jejunoileal resection. …”
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Psychometric characteristics of the Chinese version of the Columbia-Suicide Severity Rating Scale among people with mental health diagnosis by Sanrong Xiao, Qing Ge, Ting Wang, Minxuan Zhang, Anquan Hu, Xiangyang Zhang

“…Conclusions This study is the first to examine the scale factor model and the active-passive model of the C-SSRS among individuals with mental health diagnoses in China. …”
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Development of the nursing practice scale to enhance resilience in family caregivers and evaluation of its reliability and validity by Ruxin Lei, Kazuaki Tanabe, Chie Teramoto, Hiroyuki Sawatari, Mikako Yoshihara, Hisae Nakatani

“…EFA and CFA were conducted to explore the factor structure and to validate the model, respectively. The composite reliability, average variance extracted, and Cronbach’s α for each factor were calculated to confirm the factor structure and assess the validity of the model. …”
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Development and validation of the predictive scoring system for 90-day mortality in critical ill patients with exertional heatstroke by Jiali Cun, Li Zhong, Jingjing Ji, Yan Liu, Zhifeng Liu, Ming Wu

“…This study aimed to developed and validated a 90-day prognostic model for EHS patients.Methods We conducted a retrospective cohort study of patients with EHS. …”
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Prognostic value of a lncRNA signature in early-stage invasive breast cancer patients by Rong Guo, Xiting Wang, Yinju Yang, Jiaying Zou, Ming Li, Zeying Li, Yuan Yan, Nan Lan, JianYun Nie, Yiyin Tang, Guojun Zhang

“…Our study hypothesized that multivariate long non-coding RNA (lncRNA) expression profiles, when systematically integrated into a composite model, may synergistically refine postoperative risk categorization and enhance prognostic forecasting precision in this patient cohort. …”
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Crohn’s disease therapeutic dietary intervention (CD-TDI): study protocol for a randomised controlled trial by Subrata Ghosh, Levinus A Dieleman, Christopher Ma, Ian Lewis, Herman W Barkema, Humberto Jijon, Kathy D McCoy, Georgios V Gkoutos, Maitreyi Raman, Lorian M Taylor, Jeff K Vallance, Derek M McKay, David M Mutch, Deanna Gibson, Marcus Rauch

“…We aim to explore the efficacy of the CD therapeutic dietary intervention (CD-TDI), a novel dietary approach developed from best practices and current evidence, to induce clinical and biomarker remission in adult patients with active CD.Methods and analysis This study is a 13-week, multicentre, randomised controlled trial in patients with mild-to-moderate active CD at baseline. …”
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Hybrid Capsule Network for precise and interpretable detection of malaria parasites in blood smear images by Bader Alawfi

“…A novel composite loss function—integrating margin, focal, reconstruction, and regression losses—was employed to enhance classification accuracy, spatial localization, and robustness to class imbalance and annotation noise. …”
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