A randomized controlled trial utilizing an interactive accelerometer linked to a smartphone application for enhancing physical activity and health among military employees by Emilia Pietiläinen, Emilia Pietiläinen, Heikki Kyröläinen, Heikki Kyröläinen, Kai Parkkola, Kai Parkkola, Tiina Luukkaala, Tiina Luukkaala, Tommi Vasankari, Tommi Vasankari

“…IntroductionThe primary objectives of the present individualized randomized controlled trial were to increase physical activity (PA) and improve physical fitness.Materials and methods260 military employees around Finland participated. …”
Get full text

Perivascular Lymphocyte Clusters Induced by Gastric Subserous Layer Vaccination Mediate Optimal Immunity against Helicobacter through Facilitating Immune Cell Infiltration and Loca... by Chupeng Hu, Wei Liu, Ningyin Xu, An Huang, Zhiqin Zeng, Shuanghui Luo, Zhenxing Zhang, Menghui Fan, Feng Ye, Tao Xi, Yingying Xing

“…The composition of the gastric lymphocyte clusters was analyzed by immunofluorescence staining. …”
Get full text

Actions of annatto-extracted tocotrienol supplementation on obese postmenopausal women: study protocol for a double-blinded, placebo-controlled, randomised trial by Rui Wang, JaeHoon Lee, Amir Aryaie, Grant Tinsley, Bruce A Watkins, Lane Moore, Adel Alhaj-Saleh, Kartik Shankar, Sarah R Wood, Chwan-Li Shen

“…Cellular studies and high-fat-diet-induced obese mouse model mimicking obesity show the antiobesity effect of annatto-extracted tocotrienols (TT) with antioxidant capability. …”
Get full text

Mobile-Based Platform With a Low-Calorie Dietary Intervention Involving Prepackaged Food for Weight Loss for People With Overweight and Obesity in China: Half-Year Follow-Up Result... by Xi Wang, Suyuan Wang, Lingyu Zhong, Chenghui Zhang, Yanhong Guo, Mingxia Li, Li Zhao, Shuming Ji, Junjie Pan, Yunhong Wu

“…Dual-energy x-ray absorptiometry and quantitative computed tomography were used to assess body fat. A multilevel model for repeated measurements was used to compare differences between the 2 groups. …”
Get full text

Time Course of Changes in Extravascular Water of the Lung After Pneumonectomy According to the Data of Transpulmonal Thermodilution by V. V. Kuzkov, Ye. V. Suborov, V. N. Kuklin, M. Sobkhez, M. Yu. Kirov, L. Ya. Bjertnes

“…Objective: to study the accuracy of pulmonary extravascular water (PEVW) measurement by thermochromodilution (TCD) and isolated thermodilution (ITD) on a model of pneumonectomy and subsequent ventilator-induced lung lesion (VILL) in sheep.Materials and methods: the study was conducted at the Research Laboratory of University of Tromse. …”
Get full text

Lipid accumulation inhibition strategies alleviate Fusobacterium nucleatum-infected colorectal cancer by Zhongkun Zhou, Yuqing Niu, Yunhao Ma, Dekui Zhang, Yiqing Wang, Rui Ji, Jianfang Zhao, Chi Ma, Hongmei Zhu, Yingqian Liu, Lixue Tu, Juan Lu, Baizhuo Zhang, Hua Zhang, Xin Ma, Peng Chen

“…The development of treatment strategies for F. nucleatum-infected CRC is of great importance. Methods Shotgun metagenomic and metabolomic analyses of human feces, as well as metabolomic analysis of human blood, were performed to reveal the dysbiosis and metabolic dysregulation in CRC. …”
Get full text

Spectrum of γ-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes by Sara Gutiérrez Fernández, Cristina Gan Oria, Dieter Petit, Wim Annaert, John M. Ringman, Nick C. Fox, Natalie S. Ryan, Lucía Chávez-Gutiérrez

“…Methods We performed biochemical assessment of γ-secretase dysfunction on 28 PSEN2 and 19 APP mutations, including disease-associated, unclear and benign variants. …”
Get full text

The impact of <i>LEP</i> gene polymorphisms located at exon 2 (<i>LEP</i>-<i>Hin</i>fI) and intron 2 (<i>LEP-Sau</i>3AI) on growth and reproductive traits in Saanen goats by N. Senturk, T. N. Selvi, M. Demir, H. Ustuner, H. Samli, S. Ardicli

“…Population genetic analysis included the number of effective alleles, heterozygosity, polymorphism information content, and compatibility with the Hardy–Weinberg equilibrium. The general linear model procedure's least-squares methods were used for the statistical analysis. …”
Get full text

Strategies for upgrading the training of personnel at the Shanghai Municipal and district Centers for Disease Control and Prevention by HE Yongchao, SUI Mengyun, LI Yugang

“…A total of 800 questionnaires were distributed, and 768 valid questionnaires were returned, and frequency counts and composition ratios were used for statistical description.ResultsAmong the research subjects, 568 of which were females, accounting for 73.96%, with an average age of 36.51 years. …”
Get full text

A novel combined tubular 3D-printed lattice structures with coupling effects for enhancing energy absorption by A. Malekshahi, S. Jedari Salami, H. Geramizadeh, S. Dariushi

Get full text

Innovative approach to Pb (II) removal using zinc-based MOFs-derived carbon: In-depth analysis of adsorption mechanisms, isotherms, thermodynamics, and kinetics by Samira Ahmadzadeh, Alireza Hemmati

“…The experimental data were well-fitted to the Langmuir adsorption model, suggesting a maximum adsorption capacity of 1395.31 mg/g. …”
Get full text

Research on Energy-Saving Optimization of Green Buildings Based on BIM and Ecotect by Mengxue Zhao, Yuetao Yang, Shan Dong

“…Based on the resource conservation requirements of GB/T 50378-2019 “Green Building Evaluation Standard”, this study constructed a BIM–Ecotect collaborative analysis model and proposed a “four-dimensional integration” green performance optimization method. …”
Get full text

Rapid <i>Salmonella</i> Serovar Classification Using AI-Enabled Hyperspectral Microscopy with Enhanced Data Preprocessing and Multimodal Fusion by MeiLi Papa, Siddhartha Bhattacharya, Bosoon Park, Jiyoon Yi

“…This study presents a rapid, culture-independent method leveraging artificial intelligence (AI) to classify <i>Salmonella</i> serovars from rich hyperspectral microscopy data. …”
Get full text

Context-Aware Trust Prediction for Optimal Routing in Opportunistic IoT Systems by Abdulkadir Abdulahi Hasan, Xianwen Fang, Sohaib Latif, Adeel Iqbal

“…To validate the framework, we conduct a two-phase simulation-based analysis: a scenario-driven evaluation that demonstrates the model’s behavior in controlled settings, and a large-scale NS-3-based simulation comparing our method with benchmark routing schemes, including random, greedy, and AI-based protocols. …”
Get full text

Enhanced aqueous phosphate removal using chitosan-modified zirconium-loaded cork biochar by Luiza Usevičiūtė, Artūras Kaklauskas, Vaidotas Danila, Tomas Januševičius

“…This study reports the synthesis of a new adsorbent material: Zr(IV)-loaded chitosan-modified used cork stopper biochar composite (CS–CBC–Zr) beads. The suitability of CS–CBC–Zr beads for PO4–P removal was assessed using the batch method. …”
Get full text

An Innovative FRP Pre-Stressing Device for Retrofitting Reinforced Concrete Beams by Kian Aghani, Hassan Afshin, Karim Abedi

“…Pre-stressing the FRP is a promising strategy to optimize the proficiency of this method by enhancing the effectiveness of the composite and delaying debonding failures. …”
Get full text

Association between endometriosis and gut microbiota: systematic review and meta-analysis by Li Yuanyue, Li Yuanyue, Ouyang Dimei, Liu Ling, Ren Dongyan, Wu Xiaomei

“…Future research should focus on standardizing reporting methods to facilitate deeper quantitative analyses.Systematic Review RegistrationPROSPERO (registration number RD42024611701).…”
Get full text

Tongue-coating microbiota as a predictive biomarker of washed microbiota transplantation efficacy in pediatric autism: integration with clinical features by Hao-Jie Zhong, Zhao-Yu Pan, Yao-Fei Wei, Qian Yu, Lei Wu, Hong Wei, Xing-Xiang He

“…Germ-free ASD mice, colonized with healthy gut microbiota, and children with ASD treated with washed microbiota transplantation (WMT) were assessed for changes in autism symptoms and microbiota composition. Predictive models were also developed based on pre-treatment tongue-coating microbiota and clinical features to forecast WMT outcomes. …”
Get full text

Tumor associated neutrophils promote prostate cancer progression by mediating neutrophil trap secretion through PSMA1- NF-κB-HIF-1α signaling axis by Qian Dai, Qian Dai, Hua Wang, Hua Wang, Fang Li, Fang Li, Runchun Huang, Runchun Huang, Chenjun Jiang, Chenjun Jiang, Liuya Yuan, Liuya Yuan, Yayun Wang, Yayun Wang, Xun Li, Xun Li

“…Notably, the deconvolution algorithm revealed different compositions of the tumor microenvironment, with a greater proportion of neutrophils observed in the high-risk group. ③ Finally, we conducted single-cell sequencing analysis and established a prostate cancer organoid model to confirm that TANs may exacerbate the TME in PCa via neutrophil trap formation, which is mediated by the PSMA1-NF-κB-HIF-1α signaling axis. …”
Get full text

Surface Defect Detection for Small Samples of Particleboard Based on Improved Proximal Policy Optimization by Haifei Xia, Haiyan Zhou, Mingao Zhang, Qingyi Zhang, Chenlong Fan, Yutu Yang, Shuang Xi, Ying Liu

“…The method integrates the variable action space and the composite reward function and achieves the balanced optimization of different types of defect detection performance by adjusting the scaling and translation amplitude of the detection region. …”
Get full text