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4161
Application of Combined Dietary and Exercise Intervention in Pediatric Obesity and Its Impact on Anthropometric Measurements and Blood Lipid Parameters
Published 2025-06-01“…This comprehensive model may be an effective, non-pharmacological strategy for promoting healthy growth and managing childhood obesity.Keywords: obese children, combined diet and exercise intervention, physical measurements, blood lipid levels…”
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4162
Beta-Catenin Mutations Can Impact on the Interplay Between Tumor and Immune Cells and Hepatic Microbiota in Hepatocellular Cancer
Published 2025-08-01“…We hypothesized that β-catenin could modulate the immune microenvironment through alterations in the secretome and release of extracellular vesicles (EV) that mediate tumor and immune cell interactions and increase tumor growth within regions with attenuated immune activity and reduced microbial diversity.Methods: We used a synthetic transgenic murine model of β-catenin-driven hepatocarcinogenesis to analyze microbiome composition, diversity, and immune cell profiles in vivo. …”
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4163
Antioxidant Activity of <i>Radix Cyathula officinalis</i> Kuan Polysaccharides and Their Modulatory Effects on the Gut Microbiota of <i>Caenorhabditis elegans</i>
Published 2025-07-01“…Their efficacy varies according to their geographic origin and processing methods. However, the systemic anti-aging mechanisms and antioxidant efficacy of RCP have not yet been comprehensively characterized. …”
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4164
ELEMENTS OF SPORTS GYMNASTICS AS A MEANS OF IMPROVING HEALTH‐RELATED AND SKILL‐RELATED COMPONENTS OF FITNESS
Published 2025-06-01“…After analysing the data obtained by statistical methods, it was found that a statistically significant change was observed after the training programme in terms of improvement in all tested components of health‐related components of fitness: cardiorespiratory fitness, strength endurance and body composition and all tested components of skill-related components of fitness: explosive strength, speed and agility. …”
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4165
Integration of Pseudotargeted Metabolomics and Microbiomics Reveals That Hugan Tablets Ameliorate NASH with Liver Fibrosis in Mice by Modulating Bile Acid Metabolism via the Gut Mi...
Published 2025-06-01“…The underlying mechanism of HGTs was investigated by the integration of microbiomics, a pseudo-sterile model, untargeted followed by pseudotargeted metabolomics, and molecular docking. …”
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4166
Features of the implementation of the financial and legal status of municipalities, included in urban agglomerations
Published 2020-04-01“…The formation of urban agglomerations is called one of the possible forms of regulation of intergovernmental relations. The Russian model for the development of agglomerations so far follows the path of allocating inter-budget transfers from the federal budget.Agglomeration development is possible only with the interaction of all municipalities included in its composition, and the coordination of their actions, coordination of the regulatory framework of municipalities, including those aimed at optimizing budget expenditures. …”
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4167
A triterpene-enriched natural extract from Eucalyptus tereticornis modulates the expression of genes involved in adipogenesis, lipolysis, and extracellular matrix remodeling in a p...
Published 2025-12-01“…(Myrtaceae), with ursolic acid, oleanolic acid, and ursolic acid lactone mixed with minor metabolites, provided a superior antiobesity effect than reconstituted triterpenoid mixtures in adipocyte cell lines and a pre-diabetic mouse model. Further identification of the molecular mechanisms of action of this mixture of triterpenes is required.Objective This study analyzes the effect of the natural extract and its components on early RNA expression profiles in human primary cultured adipocytes and a mouse cell line.Materials and methods RNA was sequenced using the DNBseq platform and the EnrichR software to perform gene enrichment analysis using the Gene Ontology database, Kyoto Encyclopedia of Genes and Genomes, and Reactome. …”
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4168
Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage
Published 2025-02-01“…Further revealing the microbiota and related metabolic disorders in the preclinical stage of RA (pre-RA) is of great significance for exploration of disease mechanisms.Methods: DBA/1 mice were injected with type II collagen on days 0 and 21 to establish collagen-induced arthritis (CIA) mouse model. …”
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4169
Randomised controlled trial of the effects of kefir on behaviour, sleep and the microbiome in children with ADHD: a study protocol
Published 2023-12-01“…Interaction between time (preintervention/postintervention) and group (probiotic/placebo) is to be analysed using a Mixed Model Analysis of Variances.Ethics and dissemination Ethical approval for the study was granted by St Mary’s University Ethics Committee. …”
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4170
Contextual Factors, Health History, and Daily Living Activities for Ovarian Cancer Risks: A Case-Control Study in Indonesia
Published 2023-08-01“…Methods: This retrospective case-control study included 408 women with a 1:1 balanced composition: 204 women diagnosed with ovarian cancer and 204 without. …”
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4171
Vaginal Lactobacillus gasseri biosurfactant: a novel bio- and eco-compatible anti-Candida agent
Published 2025-12-01“…The environmental impact of BS was also investigated on a microcosm model (spring water) by culture-based and molecular (16S rRNA-targeted Illumina sequencing) methods, and no remarkable modifications in the taxonomy composition of the bacterial ecosystem were observed.To conclude, BS from L. gasseri BC12 appears as a promising, biocompatible and environmentally friendly approach to prevent and treat VVC/RVVC.…”
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4172
Mechanisms of osteopontin-stabilized amorphous calcium phosphate calcification in benign and pre-malignant breast disease
Published 2025-07-01“…This work aims to guide development of methods to inhibit ACP calcifications within low-risk lesions that prompt unnecessary biopsies.…”
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4173
Parabacteroides johnsonii inhibits the onset and progression of colorectal cancer by modulating the gut microbiota
Published 2025-07-01“…However, the association between P. johnsonii and CRC remains unknown. Methods P. johnsonii (10–42) and Lactococcus formosensis (22–2) were isolated from healthy human feces. 29 mice that demonstrated normal feeding and activity were randomly assigned to four groups: normal control (NC group), CRC model (IC group), P. johnsonii (PJ group), and L. formosensis (LO group). …”
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4174
Examining Organic and Elemental Carbon Presence in Beauty Salon Service Rooms
Published 2025-05-01“…The carbon matrix of these particles can carry toxic compounds, potentially adversely affecting the health of salon employees. Methods Filtres with PM2.5 were analyzed for OC and EC content with Model 4L Sunset Laboratory thermal-optical OC/EC analyser. …”
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4175
Diagnosis by SAM Linked to Machine Vision Systems in Olive Pitting Machines
Published 2025-07-01“…SAM’s ability to segment objects regardless of scene composition makes it a promising tool to improve the efficiency of olive pitting machines (DRRs). …”
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4176
The association between ultra-processed foods intake and the odds of prostate cancer: a case–control study
Published 2025-04-01“…Abstract Background Ultra-processed foods (UPFs) are characterized by poor nutritional composition and the generating neo-formed carcinogens during high levels of processing. …”
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4177
<i>Vibrio cholerae</i> Gut Colonization of Zebrafish Larvae Induces a Dampened Sensorimotor Response
Published 2025-01-01“…A growing number of studies suggest that the gut microbiome composition modulates animal behavior. Zebrafish are an established cholera model that can maintain a complex, mature gut microbiome during infection. …”
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4178
Fluorescence Spectroscopy and a Convolutional Neural Network for High-Accuracy Japanese Green Tea Origin Identification
Published 2025-04-01“…In this study, image data of the fluorescent fingerprints of green teas were collected using fluorescence spectroscopy and analyzed using a CNN model implemented in Python (ver. 3.13.2), TensorFlow (ver. 2.18.0), and Keras (ver. 3.9). …”
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4179
Effects of beinaglutide on visceral fat area and gut microbiota in obesity
Published 2025-06-01“…The Homeostatic Model Assessment of Insulin Resistance index was calculated. …”
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4180
Integrating electrical resistivity tomography and x-ray fluorescence for characterizing limestone in the Wapulaka Formation, Central Buton, Indonesia
Published 2025-07-01“…This technology facilitated the creation of a predictive model for limestone quality utilizing resistivity, enhancing resource assessments and selective mining efficacy. …”
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