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3921
Exploring Postharvest Metabolic Shifts and NOX2 Inhibitory Potential in Strawberry Fruits and Leaves via Untargeted LC-MS/MS and Chemometric Analysis
Published 2025-05-01“…<b>Background/Objectives:</b> Strawberries are highly appreciated for their rich phytochemical composition, but rapid postharvest deterioration limits their shelf life and nutritional quality. …”
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3922
Predictive value of self-prioritized mobility factors on gait speed and life space in older nigerians: A cross-sectional study
Published 2025-06-01“…The gait speed model indicates that an increase in executive function, pain, respiratory system, body composition, fatigue, social factors, racial characteristics, marital status, social network, and fear of reinjury explain about 74 % of variation in gait speed. …”
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3923
116 Acute inorganic arsenic exposure and antibiotic perturbation of the murine gut microbiome induce interindividual susceptibility to a sepsis-like disease
Published 2025-04-01“…Here, we aim to understand how baseline microbiomes from various mouse vendors impact these outcomes and characterize the observed disease. Methods/Study Population: We developed a novel mouse model where mice are exposed to an antibiotic (cefoperazone) for 2 days, followed by co-exposure to the antibiotic and 100 ppm arsenate. …”
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3924
Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration
Published 2024-12-01“…Here, we describe the development and preclinical characterization of a formulation of linezolid, a suspension of 50 mg/mL micronized powder, for intradiscal administration. Methods Micronization, particle size analysis, Franz cell diffusion assays, ex vivo bioassay, and estimates of gelling temperature were used to optimize the composition and properties of the formulation. …”
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3925
Potential mechanisms of action of Jiao'ai decoction in the treatment of premature ovarian failure: Integrated molecular pathway, gut flora, and untargeted metabolism
Published 2025-07-01“…Specifically, we evaluated the receptor for advanced glycation end (RAGE) products pathway, metabolic disorders, and intestinal flora dysbiosis. Methods: Forty female rats with normal estrous cycles were randomly divided into five groups: control, model, estradiol, low-dose JAD, and high-dose JAD, with 8 rats in each. …”
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3926
Studying the possibilities of pharmacological correction of hypoxia-induced pulmonary hypertension using a phenolic compound with a laboratory cypher KUD975
Published 2024-01-01“…The aim of our work was to study a pharmacological activity of a selective arginase-2 and thrombin inhibitor from a phenolic compounds group with a laboratory cypher KUD975 on a model of arterial pulmonary hypertension induced by hypoxia.Materials and methods. …”
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3927
Brake rigging dynamic simulation under braking on a track section with irregularities (the case of a passenger car)
Published 2020-03-01“…The simulated modeling of the brake rigging system of a passenger car with KVZ-TsNII type II trolleys equipped with shoe brakes is carried out.Results. …”
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3928
Comparative study of specific activity of rectal suppositories with clopidogrel
Published 2021-12-01“…The aim of the work is to investigate the specific activity of rectal suppositories with clopidogrel. Materials and methods. Experimental suppositories with clopidogrel 0,075 g for rectal administration were used as the objects in pre-line studies. …”
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3929
Bioactivities and Chemotaxonomy of Four <i>Heracleum</i> Species: A Comparative Study Across Plant Parts
Published 2025-04-01“…Antimicrobial activity was assessed using the broth microdilution method to determine Minimum Inhibitory Concentration (MIC) values, while antibiofilm activity was evaluated using an in vitro microplate-based biofilm model against <i>Pseudomonas aeruginosa</i> PAO1. …”
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3930
The treatment of drug-induced rhinitis with an original intranasal combination: Efficacy and safety in experimental animals
Published 2025-08-01“…The model of induced RM was confirmed by histological examination of the nasal mucosa of 3 randomly selected out of 15 animals after necropsy. …”
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3931
Factors Affecting the Ideals of Childbearing among Young People within Iranian Ethnic Groups
Published 2025-06-01“…Given Iran's diverse ethnic composition, it is crucial to explore the relationship between ethnicity and fertility. …”
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3932
Shramahara Mahakasya, a traditional polyherbal formulation, induces anti-anxiety activity in hippocampal neurons by effectuating SOD2-mediated protection against oxidative stress
Published 2025-02-01“…In this study, we investigated the intricate mechanisms through which SM polyherbal extract exerts neuroprotective and anxiolytic effects in cultured HT-22 cells and rodent models. Method: In this study, the chemical composition of SM was first identified using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS). …”
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3933
Replenishment of intracellular magnesium deficiency in cardiac arrhythmias: focus on the physicochemical properties of complex compounds
Published 2025-06-01“…To identify the most promising drug composition for replenishing intracellular magnesium deficiency by eveluating the physicochemical properties of magnesium complex compounds and conducting experiments on isolated rat atrial cardiomyocytes.Materials and methods. …”
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3934
A promising approach to diabetic osteoporosis: oxymatrine’s effects on gut microbiota and osteoblasts
Published 2025-05-01“…This study aimed to investigate its effects on diabetic osteoporosis (DOP) and explore the underlying mechanisms involving gut microbiota and osteogenic regulation. Methods In a rat model of T2DM, intragastric Oxymatrine was used to study trabecular bone repair through bone microstructure and histopathology analyses. …”
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3935
Life Cycle Assessment of Municipal Solid Waste Management Strategies in Babolsar: Evaluating Environmental Impacts and Energy Consumption
Published 2024-10-01“…This study aims to evaluate the environmental impacts of various MSWM scenarios using the Life Cycle Assessment (LCA) methodology with the IWM-2 model. Seven scenarios were examined, ranging from landfilling without energy recovery to advanced combinations incorporating composting, recycling, and energy recovery. …”
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3936
Development and validation of the Meiji Nutritional Profiling System for children
Published 2025-06-01“…BackgroundThe Meiji Nutritional Profiling System (Meiji NPS) takes into account life-stage differences and addresses specific health challenges in different age groups in Japan.ObjectivesThis study aimed to develop the Meiji NPS for younger (3–5 years) and older (6–11 years) children to encourage product reformulation and promote proper growth and development.MethodsMeiji NPS scores for 1,091 foods listed in the Japanese Food Standard Composition Table were calculated and compared with nutrient profiles (NPs) for children developed by the WHO Regional Office for the Western Pacific or Nutrient-Rich Foods Index 9.3 (NRF9.3).ResultsFor younger children, the Meiji NPS scores ranged from −442.3 to 423.9, and for older children, the Meiji NPS scores ranged from −265.5 to 386.5. …”
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3937
Research progress in near-infrared spectroscopy for detecting the quality of potato crops
Published 2025-03-01“…The technique facilitates the assessment of the composition and characteristics of the materials being analysed. …”
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3938
Clostridium Butyricum 337279 shapes the gut microbiota to attenuate metabolic disorder in diet-induced obese mice
Published 2025-05-01“…The effect of C.B on obese mice remains unclear.MethodsA high fat diet (HFD)-induced mouse model of obesity was constructed, and the mice were treated with C.B to examine their role on obesity and related metabolic disorder. …”
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3939
Comparative analysis of the fecal microbiota in Père David's deer and five other captive deer species
Published 2025-03-01“…Various factors influence the composition and function of the gut microbial community. …”
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3940
OPTIMIZATION OF INCOME OF THE PERSONNEL OF THE ENTERPRISES OF THE FOOD INDUSTRY
Published 2020-10-01“…The article proves that the successful operation of the enterprise is impossible without the coordination of the interests of the employer and its staff in the field of income generation, so this process needs to be optimized using mathematical modeling methods. Since the income of personnel, first of all, belongs to the sphere of personnel management of the enterprise, the indicators of the goal are indicators of the effectiveness of the use of labor resources. …”
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