Impact of environmental and geographical position on the chemometric classification of ethanol extracts from Isotoma longiflora leaves by E. Imelda, K. Khairan, R.R. Lubis, T. Karma, R. Idroes

“…Based on the cross-validation using linear discriminant analysis showed that the prediction model had a 100 percent accuracy. The present study thus revealed the effect of geographical location on the composition of bioactive compounds in Isotoma longiflora, suggesting the potential of chemometric techniques for quality control and assurance in traditional medicine.…”
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Nettle Leaf Water Extracts for Hepatoprotection: Insights into Bioactivity and Mitochondrial Function by Ruta Muceniece, Beatrise Luize Revina, Jorens Kviesis, Aris Jansons, Kirills Kopiks, Kaspars Jekabsons, Kristine Saleniece, Jana Namniece, Zane Grigale-Sorocina, Baiba Jansone

“…The added preservatives enhanced DPPH scavenging, while SOD-mimicking effects were comparable across extraction methods. In the liver steatosis model, the nettle extracts improved HepG2 cell viability under oxidative stress, reduced lipid accumulation, and enhanced mitochondrial oxygen consumption in the FAO pathway at mitochondria complex I. …”
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Wuling powder ameliorates diarrhea-predominant irritable bowel syndrome in mice by modulating gut mucosal microbiota and alleviating intestinal inflammation by Qianghong Tian, Donglin Yu, Junxi Shen, Leyao Fang, Ying Cai

“…This study aimed to investigate the regulatory effect of Wuling powder on intestinal mucosal microbiota in mice with diarrhea predominant-irritable bowel syndrome (IBS-D) by 16S rRNA high-throughput sequencing.MethodsMice were randomly divided into normal control group (Mc), model control group (Mm), and treatment group (Mt). …”
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Effects of SARS-CoV-2 Spike S1 Subunit on the Interplay Between Hepatitis B and Hepatocellular Carcinoma Related Molecular Processes in Human Liver by Giovanni Colonna

“…Through BioGRID, we extracted experimental data in vivo but derived it from model cell systems. The lack of patient data in STRING results prevents diagnosis or prediction of real disease progression; therefore, we can consider them “aseptic” model data. …”
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Development and Preclinical Evaluation of a Lyophilized Vaccine Against Equine Herpesvirus Type 4 (EHV-4) by Lespek Kutumbetov, Balzhan Myrzakhmetova, Aiganym Tussipova, Gulzhan Zhapparova, Talshyn Tlenchiyeva, Karina Bissenbayeva, Sergazy Nurabayev, Aslan Kerimbayev

“…The most effective stabilizer composition—sucrose, gelatin, and lactalbumin hydrolysate—was selected based on viral titer retention. …”
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Astragaloside IV alleviates GDM via regulating gut microbiota and gut microbiota metabolomic by Fengge Wang, Yongning Zhu, Hua Shu, Xiaoyun Zhang, Liting Duan, Dongmei Man, Yanping Wang

“…Astragaloside IV (AS IV), a natural and effective composition of Astragalus membranaceus, shows pharmacological effects against diabetes. …”
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The development of entrepreneurial capacity and business activity of students of educational establishments using information and communication technologies by L. A. Danchenok, N. V. Komleva, Zh. B. Musatova

“…The article is devoted to problems of organizational and methodical process modeling of the entrepreneurial potential and business activity of students of educational institutions through the use of Smart-technologies. …”
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Characterization of gut microbiota and metabolites in renal transplant recipients during COVID-19 and prediction of one-year allograft function by Zijie Wang, Xiang Gao, Hongsheng Ji, Ming Shao, Bin Ni, Shuang Fei, Li Sun, Hao Chen, Ruoyun Tan, Mulong Du, Min Gu

“…Generalized Estimating Equations (GEE) model and Latent Class Growth Mixed Model (LCGMM) were employed to dissect the relationships among clinical characteristics, laboratory tests, and gut microbiota and metabolites. …”
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Improving genomic prediction accuracy for methane emission and feed efficiency in sheep: integrating rumen microbial PCA with host genomic variation using neural network GBLUP (NN-... by Setegn Worku Alemu, Timothy P. Bilton, Patricia L. Johnson, Benjamin J. Perry, Hannah Henry, Ken G. Dodds, John C. McEwan, Suzanne J. Rowe

“…For the second objective, the NN-GBLUP model incorporating PCA-reduced RMC data improved prediction accuracy compared to standard GBLUP methods. …”
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Intestinal Microbiota Dysbiosis Disrupts the Mucosal Barrier, Triggering Inflammatory Responses in Gut-Kidney Interaction and Exacerbating Diarrhea by Shen J, Fang L, Wu Y, Deng N, Peng X, Li D, Tan Z

“…Therefore, this study will explore the mechanisms by which intestinal microbiota dysbiosis contributes to the initiation and progression of this condition.Methods: Thirty SPF-grade male KM mice were randomly assigned to three groups: the control group, the diarrhea with kidney-yang deficiency syndrome model group, and the intestinal microbiota dysbiosis + diarrhea with kidney-yang deficiency syndrome model group. …”
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Implementation of advanced control with artificial intelligence in anhydrous ethanol production by Marcos Gabriel Lopes da Silva, Davi Soares de Lima, Andréa Selene Embirassú Xavier, Allan Almeida Albuquerque

“…Additionally, artificial intelligence (AI) models—specifically decision tree, random forest, and LightGBM—were developed to control top product composition using easily measurable variables. …”
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Heavy grazing intensifies antagonistic effects of nitrogen and phosphorus addition on the water use efficiency of grasslands in Inner Mongolia by Xuebao Xu, Shiming Tang, Yanlong Li, Guangyi Lv, Tongrui Zhang, Bin Zhang, Zhaokai Sun, Zhenpeng Liu, Xinning Wang, Hongyun Yao, Cuiping Gao, Xinya Wang, Chongzhi Sun, Fengqin Yuan, Lei Zhang, Chengjie Wang

“…Structural equation modeling analysis further identified soil temperature and leaf total N as the dominant factors governing plant WUE dynamics, with both factors contributing to an increase in plant WUE. …”
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An investigation into the zoning of ecosystem sensitivity control areas in Mentougou District (Beijing, China). by Xiaodan Li, Haoyu Tao, Jing Li, Zhen Liu, Zhiping Liu

“…This model serves as a valuable framework for promoting ecological protection efforts in support of sustainable urban development objectives.…”
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Flexural strengthening of reinforced concrete cantilever beams having insufficient splice length by Moataz Badawi, Alireza Bahrami, Mohamed Ghalla, Mohamed Emara, Ehab A. Mlybari, Galal Elsamak

“…Moreover, this article includes the development of a numerical model employing the finite element method to replicate the response observed from the experimentally tested beams. …”
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Impact of variations in airborne microbiota on pneumonia infection: An exploratory study by Li Zhou, Chenchen Song, Lianlian Zhao, Zhi Guo, Yuhan Lei, Yunlin Han, Kai Gao, Yanfeng Xu, Zhiguang Xiang, Baicun Li, Jianguo Guo

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Optimization and Multimachine Learning Algorithms to Predict Nanometal Surface Area Transfer Parameters for Gold and Silver Nanoparticles by Steven M. E. Demers, Christopher Sobecki, Larry Deschaine

“…However, the expansion and testing of this model for nanoparticles of different metal composition is needed to develop a greater variety of nanosensors for medical and commercial applications. …”
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Fatty acids of erythrocyte membranes and blood serum as biomarkers for early detection of colorectal cancer by M. V. Kruchinina, V. N. Kruchinin, A. A. Gromov, M. V. Shashkov, A. S. Sokolova, I. N. Yakovina, A. A. Shestov

“…The aim of the study was to identify fatty acids (FA) of erythrocyte membranes and blood serum, which can serve as potential biomarkers for early detection of colorectal cancer.Material and methods. the study involved 65 patients with stage I-II CRC (mean age 63,3 ± 9,6 years (30 men, 35 women) and 35 people in the comparison group, matched by age and sex. the composition of fatty acids of erythrocyte membranes and blood serum was studied using a gc/ms system based on three agilent 7000B quadrupoles (USA). methods of the MATLAB software (R2019a, MathWorks) and the R programming language were used for statistical processing: t-test, unsupervised principal component analysis (PCA), Fold change, Volcano plot, machine learning method (Random Forest), Roc analysis, Heatmaps.Results. patients with stage I-II CRC showed a decrease in the level of saturated, individual monounsaturated fatty acids and a highly significant increase in the most of the polyunsaturated fatty acids with a predominance of omega-3. …”
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Weaning performance prediction in lactating sows using machine learning, for precision nutrition and intelligent feeding by Jiayi Su, Xiangfeng Kong, Wenliang Wang, Qian Xie, Chengming Wang, Bie Tan, Jing Wang

“…The models integrate farm management practices and feed nutrient composition, providing a data-driven framework for optimizing performance. …”
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Quantitative characterization and influencing factor analysis of coal structure of deep coal reservoirs in Linxing area by Xiangdong GAO, Shihao ZHOU, Hui GUO, Hao SUN, Mingda ZHANG, Chaowei LUO, Yanbin WANG, Xiang WU

“…The micro mechanical properties of coal are controlled by the composition of coal matrix and micro pore structure. …”
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Development of Lyophilisates Based on Polymer-drug and Interpolyelectrolyte Complexes: Pharmacokinetic Assessment by V. R. Timergalieva, A. Yu. Sitenkov, A. V. Sitenkova (Bukhovets), E. S. Elizarova, D. S. Gordeeva, I. I. Semina, R. I. Moustafine

“…Pharmacokinetic parameters were calculated using a model-independent method using the Thermo KinetikaTM (version 5.0, Build 5.00.11, Thermo Fisher Scientific, USA) program.Results and discussion. …”
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