Combined systemic immune-inflammatory index and prognostic nutritional index predicts the efficacy and prognosis of ES-SCLC patients receiving PD-L1 inhibitors combined with first-... by Yi Ge, Xiaoyu Liu, Yishi Xu, Yanwei Su, Yixin Li, Liping Wang

“…Therefore, the purpose of this study was to explore how the pre-treatment SII-PNI score can predict the tumor response and prognosis of extensive-stage SCLC patients treated with PD-L1 inhibitors and first-line chemotherapy.MethodsThis research conducted a retrospective review of 70 ES- SCLC patients from December 2019 to January 2023. …”
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Relationship Between the ZJU Index and Infertility Risk in Reproductive-Aged US Women: An Analysis of NHANES 2013–2018 by Tian L, Qin X, Yang M, Tang W, Feng L, Huang J, Hu H

“…This study aims to examine the association between the ZJU index and infertility in reproductive-aged women.Methods: We conducted a cross-sectional study using data from the 2013– 2018 National Health and Nutrition Examination Survey (NHANES). …”
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Relationship between IgM deposition in the mesangial region and the prognosis of IgA nephropathy: a single-centre retrospective study by Li Gao, Xuan Zhang, Dongrong Yu, Mengjie Jiang, Can Yu, Xiaohong Li, Qin Zhu

“…Abstract Objective The aim of this study was to investigate the prognostic value of mesangial IgM deposition in a long-term follow-up cohort of patients with immunoglobulin A nephropathy (IgAN). Methods A retrospective analysis of clinicopathological data from 774 patients with primary IgAN at Hangzhou Hospital of Traditional Chinese Medicine between January 1, 2016, and December 31, 2018, was conducted. …”
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Advances in research on noble gas as tracers of geofluids and helium enrichment by Yu GAO, Quanyou LIU, Dongya ZHU, Xiaoqi WU, Pengpeng LI

“…BackgroundNoble gases emerge as significant tools for tracing the sources and evolutionary processes of geofluids due to their chemical inertness and different isotopic compositions across varying reservoirs. Helium serves as a noble gas tracer and a scarce resource, and its enrichment mechanisms and exploration potential have attracted wide attention.MethodsBased on a summary of the geochemical data of typical gas reservoirs, volcanic gases, and surface hot springs at home and abroad, this study analyzed the interfering factors and end-member value screening in the source apportionment of noble gases. …”
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A blood‐based nutritional risk index explains cognitive enhancement and decline in the multidomain Alzheimer prevention trial by Gene L. Bowman, Hiroko H. Dodge, Sophie Guyonnet, Nina Zhou, Juliana Donohue, Aline Bichsel, Jeroen Schmitt, Claudie Hooper, Tamas Bartfai, Sandrine Andrieu, Bruno Vellas, MAPT/DSA Study Group, Bruno Vellas, Sophie Guyonnet, Isabelle Carrié, Lauréane Brigitte, Catherine Faisant, Françoise Lala, Julien Delrieu, Hélène Villars, Emeline Combrouze, Carole Badufle, Audrey Zueras, Sandrine Andrieu, Christelle Cantet, Christophe Morin, Gabor Abellan Van Kan, Charlotte Dupuy, Yves Rolland, Céline Caillaud, Pierre‐Jean Ousset, Françoise Lala

“…The primary outcome in MAPT was a cognitive composite Z score within each participant that was fit with linear mixed‐effects models. …”
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Estimating complications and mortality in patients with post-surgical chronic hypoparathyroidism in England: A retrospective matched cohort study by Narendra L. Reddy, Caoimhe T. Rice, Sara J. Carvalho, Jennifer A. Davidson, Elizabeth Glenister, Christopher T. Sibley, Alden R. Smith, Wahidullah Noori

“…Regression models were adjusted for potential confounding variables where possible. …”
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Screen Time Is Associated With Cardiometabolic and Cardiovascular Disease Risk in Childhood and Adolescence by David Horner, Marie Jahn, Klaus Bønnelykke, Bo Chawes, Trine Flensborg‐Madsen, Ann‐Marie Malby Schoos, Jakob Stokholm, Morten Arendt Rasmussen

“…Background Screen time in children and adolescents may be linked to cardiometabolic and cardiovascular risk. Methods We analyzed data from >1000 participants in the COPSAC2010 and COPSAC2000 (Copenhagen Prospective Studies on Asthma in Childhood) mother–child 2000 and 2010 cohorts. …”
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Long-term exposure to multiple air pollutants and multi-level socioeconomic status: joint effects on age-related macular degeneration, subsequent ocular comorbidity, and death in m... by Yang Yang, Liangkai Chen, Qichen Liu, Min Mu, Jing Huang, Guangming Zhang, Qianqian Song

“…However, no study has explored the combined effects of air pollutants and SES on (1) age-related macular degeneration (AMD) incidence; (2) trajectories from baseline to AMD, subsequent ocular comorbidity (OCMD), and mortality; and (3) life expectancy in middle-aged and older adults. Methods Using UK Biobank data, we created two composite air pollution scores (APS) and assessed SES at individual and neighborhood levels. …”
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Baseline type 2 biomarker levels and clinical remission predictors in children with asthma by Mengmeng Chen, Mengmeng Chen, Congcong Li, Qiuyan Yang, Huijie Zhang, Yanli Zhang, Na Wang, Na Wang, Jingcheng Dong, Jingcheng Dong

“…BackgroundFew studies have investigated the relationship between baseline type 2 biomarker levels and clinical features in pediatric asthma, particularly in different asthma stages, which may inform prognosis and remission.ObjectiveTo explore the association between baseline Th2 biomarker levels and clinical manifestations in pediatric asthma, identifying predictors of clinical remission.MethodsThe study included 172 children with a mean age of 6.87 ± 3.04 years, comprising 119 asthma patients and 53 non-respiratory symptom controls. …”
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Hydrophilic and superoleophobic GO-TiO2 PVDF/PEI membrane with antifouling properties for efficient oil-water separation by Mitushi Agrawal, Triparna Chakraborty, Dharmveer Yadav, Sumit Saxena, Shobha Shukla

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Association between isolated abnormal 1-hour glucose challenge test and adverse pregnancy outcomes: a retrospective review from an urban tertiary care center in the United States by Hillary Hosier, Lisbet S. Lundsberg, Jennifer Culhane, Caitlin Partridge, Moeun Son

“…Abstract Background The objective of this study was to investigate whether an isolated abnormal 1-hour glucose challenge test (GCT) among patients without gestational diabetes (GDM) is associated with adverse outcomes. Methods This is a retrospective cohort study of patients who underwent GDM screening at ≥ 24 weeks’ gestation with a 1-hour GCT and delivered a singleton fetus at > 35 weeks’ gestation at an urban tertiary hospital from 1/2013 to 10/2021. …”
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Protocol for an observational study to assess the impact of pharmacogenetics on outcomes in vascular surgery (PROSPER) by John H McDermott, William G Newman, Stuart Wright, Kerry Anne Burke, Selman Mirza, Nicholas S Greaves

“…It will consider whether pharmacogenetics can be used to ensure patients are prescribed effective medications to optimise their outcomes.Methods and analysis This is an observational cohort study of patients undergoing lower limb surgical, endovascular or hybrid revascularisation for CLTI at Manchester University NHS Foundation Trust. …”
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IL-17A Levels and Progression of Kidney Disease Following Hospitalization with and without Acute Kidney Injury by Jason A. Collett, Alexander H. Flannery, Lucas J. Liu, Tomonori Takeuchi, David P. Basile, Javier A. Neyra

“…In adjusted multivariable models, IL-17A levels were not independently associated with progression of kidney disease. …”
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Association of urbanization-related factors with tuberculosis incidence among 1992 counties in China from 2005 to 2019: a nationwide observational study by Yaping Wang, Xiaoqiu Liu, Yuhong Li, Min Liu, Yiheng Wang, Hongliang Zhang, Jue Liu, Yanlin Zhao

“…We aimed to assess the association between urbanization factors and TB incidence in China. Methods We evaluated urbanization at the county level in China from 2005 to 2019 using a composite index integrating population density, gross domestic product (GDP, per capita), hospital beds per 1000 population, nighttime light (NTL), and normalized difference vegetation index (NDVI). …”
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Advances and trends of non-marine shale sedimentology: A case study from Gulong Shale of Daqing Oilfield, Songliao Basin, NE China by Longde SUN, Rukai ZHU, Tianshu ZHANG, Yi CAI, Zihui FENG, Bin BAI, Hang JIANG, Bo WANG

“…Such research will focus on eight aspects: lithofacies and organic matter distribution prediction under a sequence stratigraphic framework for non-marine shale strata; lithofacies paleogeography of shale strata based on the forward modeling of sedimentation; origins of non-marine shale lamina and log-based identification of lamina combinations; source of organic matter in shale and its enrichment process; non-marine shale lithofacies classification by rigid particles + plastic components + pore-fracture system; multi-field coupling organic-inorganic interaction mechanism in shale diagenesis; new methods and intelligent core technology for shale reservoir multi-scale characterization; and quantitative evaluation and intelligent analysis system of shale reservoir heterogeneity.…”
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Iranian university students’ alcohol-related knowledge, attitude, and practice questionnaire (ISKAP alcohol Q): development and psychometric properties by Mahsa Janati, Nouzar Nakhaee, Ali Karamoozian, Somayeh Alizadeh, Mostafa Yazdani, Hamid Sharifi, Abedin Iranpour

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Association between lower geriatric nutritional risk index and low cognitive functions in United States older adults: a cross-sectional study by Jiuling Liu, Melysze Deanne Oorloff, Adithya Nadella, Ning Zhou, Min Ye, Yifeng Tang, Yuanwei Wang

“…BackgroundWe aimed to explore the association between the Geriatric Nutritional Risk Index (GNRI) and the risk of low cognitive functions among older adults in the United States (US).MethodsUtilizing data from the National Health and Nutrition Examination Study (NHANES) database, a cross-sectional analysis was conducted. …”
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Optimal timing of anticoagulation after acute ischaemic stroke with atrial fibrillation (OPTIMAS): statistical analysis plan for a randomised controlled trial by Norin Ahmed, Hakim-Moulay Dehbi, Nick Freemantle, Jonathan Best, Philip S. Nash, James K. Ruffle, David Doig, David J. Werring

“…Here, we describe in detail the statistical aspects of OPTIMAS, including outcome measures, sample size calculation, general analysis principles, descriptive statistics, statistical models, and planned subgroup analyses. Study outcomes The primary outcome is a composite of recurrent stroke (ischaemic stroke or symptomatic intracranial haemorrhage) and systemic arterial embolism within 90 days. …”
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Longitudinal Lipid Trajectories and Progression of CKD in Children by Uwe Querfeld, Marietta Kirchner, Francesca Mencarelli, Karolis Azukaitis, Aysun Bayazit, Ali Duzova, Anke Doyon, Nur Canpolat, Ipek Kaplan Bulut, Lukasz Obrycki, Justine Bacchetta, Rukshana Shroff, Dusan Paripovic, Cengiz Candan, Jerome Harambat, Alev Yilmaz, Harika Alpay, Jun Oh, Hakan Erdogan, Claus P. Schmitt, Anette Melk, Franz Schaefer

“…Introduction: There are discrepant findings regarding the effect of dyslipidemia on disease progression in adult patients with chronic kidney disease (CKD). Methods: In a prospective cohort study of children with stage 3 to 5 (predialysis) CKD, triglycerides (TGs), total cholesterol (CHOL), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) were measured semiannually. …”
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Computerized cognitive testing to capture cognitive decline in Alzheimer's disease: Longitudinal findings from the ARMADA study by Roos J. Jutten, Emily H. Ho, Tatiana Karpouzian‐Rogers, Carol van Hulle, Cynthia Carlsson, Hiroko H. Dodge, Cindy J. Nowinski, Richard Gershon, Sandra Weintraub, Dorene M. Rentz

“…We investigated whether the NIH Toolbox for Assessment of Neurological and Behavioral Function—Cognition Battery (NIHTB‐CB) detects AD‐related cognitive decline. METHODS N = 171 participants (age 76.5 ± 8; 53% female, 34% Aβ‐positive) from the ARMADA study completed the NIHTB‐CB at baseline, 12 months, and 24 months. …”
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