Comprehensive experimental study of multivariable oil–brine–rock interactions: impact of brine–rock chemistry and crude oil polarity on enhanced oil recovery in carbonate reservoir... by Azadeh Amrollahi Biyouki, Nosrat Izadi, Samaneh Bovard, Yasaman Tahernezhad, Nashaat Nassar, Ebrahim Ghafar-Zadeh

“…Abstract Reservoir wettability alteration is a vital method for enhancing oil recovery, especially at the pore scale, where it plays a key role in optimizing extraction and minimizing risks from chemical and water flooding. …”
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Comparison of torch with electric arc casting in the lost wax technique for the cast dental stud protocol. by Víctor Hugo Gonzalo Quispe Mamani, César Alberto Luna Castillo, Dina Miryan Alanoca Sejje, Luis Alexander Orrego-Ferreyros

“…The aim of this study was to compare the compressive strength, microstructural characteristics, and cost-effectiveness of cast dental posts fabricated using two techniques: torch casting (TC) and electric arc casting (EAC), both integral to the lost wax method. Employing an applied research approach with an experimental design, the study analyzed 40 non-precious gold (NPG) alloy cast posts, divided equally into two groups of 20 for each technique. …”
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Social Representations of Breast Cancer in Patients, Accompanying Relatives and Specialists by Maria Elena Reina Suarez, Yamila Ramos Rangel, María de los Ángeles Reina Sarmiento, Leonor Cisneros Pimentel, María del Rosario Lleó Moreno, Sara Soraya Naranjo Noda

“…<br /><strong>Objective:</strong> to determine the structure of the social representations (attitude, information, representational field) of breast cancer in the study subjects. <br /><strong>Methods:</strong> exploratory, cross-sectional study, of mixed methodology, in the period from May 2014 to December 2015. …”
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Push Factors of Population Migration in Russian Regions in Terms of Age Structure by Evgeniya Mikhailovna Moiseeva

“…of migration using econometric methods. Namely, regression models are estimated on panel data for 85 constituent entities of the Russian Federation for the five-year period from 2019 to 2023. …”
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Protocol for a randomised controlled trial of a weight maintenance intervention to promote fat loss in pregnant individuals with obesity by Suzanne Phelan, Leanne M Redman, Aaron B Caughey, Daniel S Hsia, John W Apolzan, Robbie A Beyl, Abby D Altazan, Madison S Dickey, Emerson Simeon, Emily W Flanagan, Hannah E Cabre, Joshua R Sparks, Maryam Kebbe, Amy M Valent, Elaine Yin, Sarah K Keadle

“…The objective of this proof-of-principle randomised controlled trial is to test the effect of a gestational fat mass loss intervention in pregnant individuals with obesity on changes in weight, fat mass and cardiometabolic disease risk factors.Methods and analysis In this two-site randomised parallel group, 100 women (30% black; 30% Hispanic) with pre-existing obesity (31.0≤body mass index≤55.0 kg/m2) are randomised to usual care (Provider Directed Group) or usual care plus a fat mass loss intervention with food provision (Weight Maintenance Group). …”
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Treatment of hypothyroidism with levothyroxine plus slow-release liothyronine: a study protocol for a randomized controlled double-blinded clinical trial by F. Azizi, A. Amouzegar, H. Abdi, M. Tohidi, S. Masoumi, D. Khalili, Y. Mehrabi, A. Zadehvakili, M. Hedayati, A. A. Momenan, L. Mehran

“…Before and after the intervention, body weight, heart rate, blood pressure, ECG, quality of life (by ThyPRO-39 and SF-12), resting energy expenditure, and body composition will be evaluated. Also, serum TSH, total T3, total T4, free T4, free T3, total cholesterol, LDL, HDL, triglycerides, fasting blood sugar (FBS), insulin, HbA1C, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), sex hormone-binding globulin (SHBG), enolase, lactate dehydrogenase (LDH), creatin kinase (CK), ferritin, and metabolomics will be assessed at baseline and compared with their corresponding values at 24 and 48 weeks. …”
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Investigating the mediating role of emotional intelligence in the relationship between internet addiction and mental health among university students. by Girum Tareke Zewude, Derib Gosim, Seid Dawed, Tilaye Nega, Getachew Wassie Tessema, Amogne Asfaw Eshetu

“…Various analyses were conducted to achieve the stated objectives, including Cronbach's alpha and composite reliabilities, bivariate correlation, discriminant validity, common method biases, measurement invariance, and structural equation modeling (confirmatory factor analysis, path analysis, and mediation analysis). …”
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Exploring the glucose-lowering and anti-inflammatory immune mechanism of artemether by AMPK/mTOR pathway and microbiome based on multi-omics by Tao Jiang, Peipei Du, Dongxia Liu, Hetao Chen, Yujin Ma, Bin Hu, Jingna Li, Hongwei Jiang, Xuejiao Li

“…This research aimed to elucidate the impact of ATM on glucolipid metabolism in a type 2 diabetes mellitus (T2DM) model db/db mice and what kind of role the gut microbiota played, and explored the underlying mechanisms involved.MethodsC57BL/KsJ-db/db mice were treated with 80 and 160 mg/kg of ATM for 8 weeks, with metformin as a positive control.ResultsATM treatment (160 mg/kg) observably ameliorated insulin resistance (IR), hyperglycemia, hyperlipemia and pathological injury in the liver and pancreas. …”
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Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity by Valentina Salvi, Carolina Gaudenzi, Barbara Mariotti, Gaia Giongrandi, Silvia Alacqua, Veronica Gianello, Tiziana Schioppa, Laura Tiberio, Angela Ceribelli, Carlo Selmi, Paolo Bergese, Stefano Calza, Annalisa Del Prete, Silvano Sozzani, Flavia Bazzoni, Daniela Bosisio

“…Methods To mimic the onset of psoriasis, keratinocytes were treated with a cocktail of psoriatic cytokines or UV-irradiated. …”
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Modified Huanjingjian Prevents Chemotherapy-Induced Alopecia by Inhibiting Genomic DNA Methylation of the Wnt Signaling Pathway in Mice by Liu X, Du T, Xi R, Cheng L, Wang Y, Lu H, Guo D, Zhu J, Liu T, Li F

“…And our main aim was to explore the efficacy and the mechanism of MHJJ in mice.Methods: UPLC-QE-Orbitrap-MS characterized MHJJ’s chemical composition. …”
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ARCHITECTONICS OF THE SILENCE IN VERCORS’ NOVEL “THE SILENCE OF THE SEA” by Tatyana A. Pakhareva

“…The combination of the structural-semiotic, contextual, and holistic methods during the story analysis allowed us to come to the conclusion that compositionally the “silence of the sea”, which corresponds to the “surface/depth” structure, is implemented in Vercors’ story in a similar way to L. …”
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DHLCA Alleviates Diabetic Kidney Disease via TGR5/FXR Activation and Gut Microbiota Remodeling by Zhou H, Mu X, Hu H, Zhao S, Hu N, Yang M, Jiang J

“…This study aimed to investigate the role of BA metabolism in the progression of DKD.Methods: Plasma BA profiles were measured in healthy controls (HC), patients with type 2 diabetes mellitus (T2DM), and patients with DKD using ultra-high-performance liquid chromatography–tandem mass spectrometry (UPLC-MS/MS). …”
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Personalised azithromycin+metronidazole (PAZAZ), in combination with standard induction therapy, to achieve a faecal microbiome community structure and metagenome changes associate... by Marc A Benninga, Melvin B Heyman, Anthony Otley, Tim de Meij, Wouter J de Jonge, Charlotte M Verburgt, Katherine A Dunn, Sofia Verstraete, Withney Sunseri, Francisco Sylvester, Andre Comeau, Morgan Langille, Johan E Van Limbergen

“…We describe the protocol of a pilot study assessing feasibility of treatment allocation based on baseline faecal microbiome profiles.Methods and analysis This is a 52-week, multicentre, randomised, controlled, open-label, add-on pilot study to test the feasibility of a larger multicontinent trial evaluating the efficacy of adjuvant antibiotic therapy in 20 paediatric patients with mild-to-moderate-CD (10&lt;PCDAI≤37.5; PCDAI, Pediatric Crohn’s Disease Activity Index). …”
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Therapeutic effects and mechanisms of Fufang Longdan mixture on metabolic syndrome with psoriasis via miR-29a-5p/IGF-1R axis by Guangyun Luo, Guangyun Luo, Xiangyi Kong, Fang Wang, Zhiming Wang, Zhuo Zhang, Huan Cui, Yiwen Zhang, Wen Huang, Xuesong Yang, Jianzhou Ye, Jianzhou Ye

“…However, current treatments have shown limited efficacy in improving the symptoms of both conditions simultaneously.ObjectiveThis study aimed to investigate the therapeutic efficacy of Fufang Longdan Mixture (FLM) in treating MS-P comorbidity, elucidate its mechanism through the miR-29a-5p/IGF-1R axis and evaluate treatment responses between APOE−/− and C57BL/6 mice.MethodsUPLC-Q-exactive-MS/MS analysis was used to characterise FLM’s chemical composition. …”
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Meta‐analysis of cardiac magnetic resonance in prognosticating left ventricular function in peripartum cardiomyopathy by Hawani Sasmaya Prameswari, William Kamarullah, Raymond Pranata, Iwan Cahyo Santosa Putra, Alberta Claudia Undarsa, Mohammad Iqbal, Triwedya Indra Dewi, Nuraini Yasmin Kusumawardhani, Mohammad Rizki Akbar, Astri Astuti

“…We aimed to describe CMR's prognostic value in predicting poor left ventricular (LV) function recovery using late gadolinium enhancement (LGE) and T2‐weighted or T2 mapping. Methods and results PubMed, Europe PMC, and ScienceDirect were screened for studies on late gadolinium enhancement (LGE) and myocardial oedema using CMR and PPCM. …”
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“Agent – Environment” Evolution Mechanism of Greenbelt from the Perspective of Complex Adaptive System: A Case Study of Beijing’s Greenbelts by Song LIU, Peiyu SHEN, Dizi LIU, Zhaocheng BAI

“…This research takes Beijing’s greenbelts (the first greenbelt and the second greenbelt) as an example to, according to the “bottom-up” research paradigm of complex adaptive system theory (CAS), depict the adaptation process of multiple agents to promote the evolution of the greenbelt system, and explore the evolution mechanism of greenbelt, so as to seek targeted solutions to optimize greenbelt planning and promote the implementation of greenbelt policies.MethodsBased on the theory of complex adaptive system, the characteristics of the greenbelt system are analyzed from the perspectives of basic characteristics, structural composition and adaptive mechanism. …”
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Amelioration of Metabolic Syndrome by Co-Administration of <i>Lactobacillus johnsonii</i> CRL1231 and Wheat Bran in Mice via Gut Microbiota and Metabolites Modulation by Matias Russo, Antonela Marquez, Estefanía Andrada, Sebastián Torres, Arlette Santacruz, Roxana Medina, Paola Gauffin-Cano

“…Methods: Mice were divided into three groups and fed for 14 weeks as follows: the Control group (standard diet), the MS group (HFD+WB), and the MS+Lj group (HFD+WB and <i>Lj</i> CRL1231-dose 10⁸ cells/day). …”
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Association between the early or late onset of gestational diabetes mellitus with neonatal adverse outcomes: a retrospective cohort study by Fabiana Vieira Duarte de Souza Reis, Carlos Izaias Sartorão Filho, Luis Sobrevia, Caroline Baldini Prudencio, Bruna Bologna, Luana Favaro Iamundo, Adriely Magyori, Luiz Takano, Raissa Escandiussi Avramidis, Rafael Guilen de Oliveira, Marilza Vieira Cunha Rudge, Angélica Mércia Pascon Barbosa, Diamater Study Group

“…We aimed to investigate the association between early-onset GDM and adverse outcomes in newborns and neonates, comparing it with the late-onset GDM model. Methods It was a retrospective cohort study conducted at the Perinatal Diabetes Research Center in Assis/SP, affiliated with the Botucatu Medical School-UNESP in Brazil. …”
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A Polysorbate-Based Lipid Nanoparticle Vaccine Formulation Induces In Vivo Immune Response Against SARS-CoV-2 by Aishwarya Saraswat, Alireza Nomani, Lin-Kin Yong, Jimmy Chun-Tien Kuo, Heather Brown, Muralikrishna Narayanareddygari, Avery Peace, Rizan Fazily, Timothy Blake, Christopher D. Petro, Bindhu Rayaprolu, Johanna Hansen, Amardeep Singh Bhalla, Mohammed Shameem

“…By leveraging PS-80’s unique structural properties, this study aimed to develop an mRNA-LNP platform with improved extrahepatic delivery and robust freeze/thaw tolerance. <b>Methods</b>: We employed a stepwise optimization to establish both the lipid composition and formulation buffer to yield a stable, high-performing PS-80-based SARS-CoV-2 mRNA-LNP (SC2-PS80 LNP). …”
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Active learning for advanced biodegradable film design by Yi Gao, Chengcheng Liu, Yang Zhao, Peng Zhao, Feihui Chen, Qinghai Li, Yanguo Zhang, Bin Yang, Hui Zhou

“…Through six iterations with 186 data points for three-target optimization and seven iterations with 166 data points for two-target modeling, a data-driven platform was established to accurately predict CMC film properties based on composition and autonomously identify optimal formulations for specific performance targets. …”
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