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4561
Novel Cascaded Multilevel Regulated Voltage Control for Distribution Network
Published 2016-01-01“…Its main circuit topology and equivalent mathematical model were introduced, and the composite segmented controller was designed. …”
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4562
Electrospun textiles from decellularized bovine pericardium and polyvinyl alcohol (PVA) supporting blood coagulation: innovative approach in biomaterials for research purposes
Published 2025-08-01“…Different patch formulations to support blood clotting are characterized in the present study.MethodsThe approach used is based on electrospun decellularized bovine pericardium (dECM) blended or layered with polyvinyl alcohol (PVA) and crosslinked by (3‐Glycidyloxypropyl)trimethoxysilane (GPTMS). …”
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4563
Comparative evaluation of osteogenic activity and the effect on hematopoietic function of bone marrow of fractions of Saussurea controversa and Filipendula ulmaria extracts in expe...
Published 2019-10-01“…The aim of the work was to study the effect of fractions from Saussurea controversa and Мeadowsweet extracts on hemopoiesis and regeneration of bone tissue, which are the main target indicators in experimental osteomyelitis.Materials and methods. In the experiment we used butanol, water and element-organic fractions from the Saussurea controversa extract as well as ethyl acetate, butanol and water fractions from the Мeadowsweet extract, obtained by liquid extraction of the extracts from corresponding plants with the help of organic solvents. …”
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4564
D-glucaro-1,4-lactone alleviates acetaminophen-induced hepatotoxicity in mice via modulating gut microbiota and metabolites associated with Lactobacillus–glutamine and nicotinic ac...
Published 2025-07-01“…ObjectiveThis study investigated the hepatoprotective effect and underlying mechanisms of D-glucaro-1,4-lactone (1,4-GL), a natural compound found in fruits and vegetables, against acetaminophen (APAP)-induced acute liver injury (ALI) in mice, which had not been previously explored.MethodsA stable ALI model was established in male C57BL/6J mice using 300 mg/kg APAP after fasting. …”
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4565
Predicting drug-target interactions using machine learning with improved data balancing and feature engineering
Published 2025-06-01“…This dual feature extraction method enables a deeper understanding of chemical and biological interactions, enhancing predictive accuracy. …”
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4566
Energy technology complexes as regulators of electrical power systems
Published 2019-12-01“…The aim of the work is to study the processes of electrothermal gasification of solid fuels in energy technological complexes and to assess the possibilities of using energy technological complexes for regulating load schedules of electric power systems. By the methods of mathematical and physical modeling of physicochemical processes of gasification of solid carbon- containing materials and energy conversion, the main characteristics of electro-technological complexes for the processing of solid carbon-containing materials are obtained. …”
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4567
Exploring the Comparative Impact of Red and White Meat on Cardiovascular Diseases: A Global Cross‐Sectional Ecological Study
Published 2025-07-01“…This phenomenon is worth exploring, considering that there is no substantial difference in composition between red meat and white meat. Methods Country‐specific data were extracted from United Nations agencies to analyse and compare the statistical roles of red meat and white meat in contributing to CVD incidence. …”
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4568
The effect of the aqueous and methanol fennel stem extracts (Foeniculum vulgare Miller) on isolated rat ileum contractility
Published 2018-01-01“…The study was aimed to investigate the effects of aqueous and methanol fennel stem extracts on intestinal activity. Methods. Relaxant activity of aqueous and methanol fennel stem extracts was evaluated in vitro in three experimental models: spontaneous contraction, acetylcholine and potassium chloride (KCl)-induced contraction of an isolated rat ileum. …”
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4569
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4570
Correction of Structural Changes in Thymus by <i>Gentiana algida</i> Pall Extract at Experimental Azathioprine Immunosuppression
Published 2020-11-01“…The purpose of the study is to evaluate the effect of Gentiana algida Pall dry extract on microanatomy of CBA mice thymus at azathioprine immunosuppression. Material and Methods. Experiments were carried out on CBA male mice. …”
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4571
Biodegradable natural polymers and fibers for 3D printing: A holistic perspective on processing, characterization, and advanced applications
Published 2024-12-01“…Reinforcements derived from nature have provided better tensile strength, moduli, and flexural properties when infused into polymer matrices, such as PLA, ABS, and PP. Extrusion-based methods, comprising Fused Deposition Modeling (FDM)/Fused Filament Fabrication (FFF), are the most applied techniques of 3D printing for natural-polymer and fiber composites with a principal application in the medical and industrial domains. …”
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4572
Immune Responses Elicited by Outer Membrane Vesicles of Gram-Negative Bacteria: Important Players in Vaccine Development
Published 2024-12-01“…A key information was that the used purification procedures for OMVs, the induction methods to increase the production of OMVs as well as the specific mutant strains obtained via genetic engineering affect the composition of potential antigens on the surface and in the lumen of the OMVs. …”
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4573
Global, Regional, and National Burden of Smoking-Related Diseases and Associations With Health Workforce Distribution, 1990–2021: Analysis From the Global Burden of Disease Study 2...
Published 2025-07-01“…ObjectivesTo analyze global trends in smoking-related disease burden from 1990–2021 and examine associations with health workforce distribution across countries.MethodsWe analyzed smoking-related deaths and disability-adjusted life years using Global Burden of Disease 2021 data for 204 countries. …”
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4574
ITIH4 alleviates OVA-induced asthma by regulating lung-gut microbiota
Published 2025-05-01“…This study investigated the effects of ITIH4 on the modulation of lung and gut microbiota, the attenuation of allergic inflammation, and the improvement of respiratory outcomes in an asthma mouse model. Methods Six-week-old male Balb/c mice were divided into five groups: control, ITIH4, ovalbumin (OVA), and two OVA + ITIH4 treatment groups at different doses. …”
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4575
Influence of programmed death ligand 1 (PD-L1) knockout on gut microbiota in experimental autoimmune uveitis
Published 2025-05-01“…This study aims to investigate the effect of PD-L1 knockout on gut microbiota in an experimental autoimmune uveitis (EAU) model.MethodsEAU was induced via immunization with interphotoreceptor retinoid-binding protein peptide 651-670 (IRBP651-670) in either wild type (WT) or PD-L1 knockout (KO) C57BL/6J female mice. …”
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4576
Polygonatum cyrtonema Hua polysaccharides alleviate muscle atrophy and fat lipolysis by regulating the gut microenvironment in chemotherapy-induced cachexia
Published 2025-03-01“…This research endeavored to assess the medicinal efficacy of PCPs in alleviating muscle atrophy and fat lipolysis and explore the potential mechanisms.Methods: A cancer cachexia model was induced by male C57BL/6 mice bearing Lewis lung tumor cells and chemotherapy. …”
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4577
Safety, Immunogenicity and Protective Activity of a Modified Trivalent Live Attenuated Influenza Vaccine for Combined Protection Against Seasonal Influenza and COVID-19 in Golden S...
Published 2024-11-01“…The trivalent LAIV/CoV-2 composition was compared to the classical 3×LAIV in the golden Syrian hamster model. …”
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4578
Biodegradable Electrospun PLGA Nanofibers-Encapsulated Trichinella Spiralis Antigens Protect from Relapsing Experimental Autoimmune Encephalomyelitis and Related Gut Microbiota Dys...
Published 2025-02-01“…However, whether timely controlled delivery of ESL1 antigens in vivo, as in natural infections, could enhance its therapeutic potential for MS is still unknown.Methods: To test this, we encapsulated ESL1 antigens into biodegradable poly (lactide-co-glycolic) acid (PLGA) nanofibers by emulsion electrospinning as a delivery system and assessed their release dynamics in vitro, and in an animal MS model, experimental autoimmune encephalomyelitis (EAE), induced 7 days after PLGA/ESL1 subcutaneous implantation. …”
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4579
Bioactive compound combinations from Rhodiola tangutica alleviate pulmonary vascular remodeling in high-altitude pulmonary hypertension rats through the PI3K–AKT pathway
Published 2025-05-01“…Although its active fraction (ACRT) shows therapeutic potential for HAPH, the main pharmacodynamic substances remain unclear due to its complex composition.AimsThis study aimed to identify bioactive equivalent combinatorial components (BECCs) of ACRT that alleviate pulmonary vascular remodeling in HAPH rats and explore the underlying pharmacological mechanisms.MethodsSeventy adult Sprague–Dawley rats were divided into control, hypoxia, hypoxia + ACRT (150 mg/kg), hypoxia + BECCs (25, 50, and 100 mg/kg), and hypoxia + sildenafil (30 mg/kg) groups. …”
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4580
Late bedtime was associated with increased androgen and reduced lean mass in women with polycystic ovary syndrome: a cross-sectional study
Published 2025-07-01“…The present study aimed to investigate the relationship between bedtime, androgen-associated traits, and dual-energy X-ray absorptiometry (DEXA)-based lean mass (LM) in polycystic ovary syndrome (PCOS). Methods This cross-sectional study recruited 899 reproductive-aged women with PCOS from the PCOS subspecialty clinic at Shanghai Tenth People’s Hospital, and finally, 636 women were included in the study. …”
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