Multipath and Deep Learning-Based Detection of Ultra-Low Moving Targets Above the Sea by Zhaolong Wang, Xiaokuan Zhang, Weike Feng, Binfeng Zong, Tong Wang, Cheng Qi, Xixi Chen

“…First, the image features of the target, multipath, and sea clutter in the real-measured range-Doppler (RD) map are analyzed, based on which the target and multipath are defined together as the generalized target. Then, based on the composite electromagnetic scattering mechanism of the target and the ocean surface, a scattering-based echo generation model is established and validated to generate sufficient data for DL network training. …”
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Analytical Solution for the Deformation and Support Parameters of Coal Roadway in Layered Roof Strata by Kai Wang, Bao-gui Yang, Zhong-kui Wang, Xiao-long Wang

“…The traditional supporting design method of the layered roof support in coal roadways is the engineering analogy method, which depends on experiences rather than theoretical analysis. …”
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The combination of Clostridium butyricum and Akkermansia muciniphila mitigates DSS-induced colitis and attenuates colitis-associated tumorigenesis by modulating gut microbiota and... by Dengxiong Hua, Qin Yang, Xiaowei Li, Xuexue Zhou, Yingqian Kang, Yan Zhao, Daoyan Wu, Zhengrong Zhang, Boyan Li, Xinxin Wang, Xiaolan Qi, Zhenghong Chen, Guzhen Cui, Wei Hong

“…This may be a natural and relatively safe method to support the gut microbiota and enhance the host’s immunity against cancer.IMPORTANCEOur study suggests that the combined administration of CB and AKK probiotics, as opposed to a single probiotic strain, holds considerable promise in preventing the advancement of IBD to CRC. …”
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Lactational performance effects of 3-nitrooxypropanol supplementation to dairy cows: A meta-regression by L.F. Martins, M. Maigaard, M. Johansen, P. Lund, X. Ma, M. Niu, A.N. Hristov

“…Dose (± SD; 77.0 ± 33.17 mg 3-NOP/kg DMI), forage-to-concentrate ratio (FC; 58.9 ± 8.83%, expressed as average ± SD% of forage in the diet), dietary concentrations of CP, ether extract, NDF, and starch (16.3 ± 1.84%, 4.3 ± 1.03%, 33.7 ± 4.40%, and 20.9 ± 3.97%, as average ± SD% of DM, respectively), supplementation length (days), and DIM and BW of the cows at the beginning of the study were used as continuous explanatory variables. Mixed-effects models were fitted using the robust variance estimation method. …”
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Magnetically sensitive nanocomposites and magnetic liquids based on magnetite, gemcitabine, and antibody HER2 by A. L. Petranovska, M. V. Abramov, N. M. Оpanashchuk, S. P. Turanska, P. P. Gorbyk, N. V. Kusyak, A. P. Kusyak, N. Yu. Lukyanova, V. F. Chekhun

“…The average value of the thickness of the adsorbed layer of GC in the composition of Fe3O4@GC NC is 2.4±0.1 nm, as evaluated by the method of magnetic granulometry. …”
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What makes equity crowdfunding successful in Japan? Testing the signaling and lack of financial literacy hypotheses by Yoshiaki Nose, Chie Hosomi

“…This study is unique in that it focuses on funding method differences as well as the contents of the business plans disclosed in the ECF campaigns. …”
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Electrocaloric Effect in Multilayer Ferroelectric Structures by Alexander S. Starkov, Alexander S. Anokhin, Andrey V. Es'kov, Alexander A. Semenov, Andrey L. Kholkin

“…Development of a mathematical model quantifying the ferroelectric polarization, static dielectric constant, as well as pyroelectric and electrocaloric properties of multilayered ferroelectric film structures.Materials and methods. …”
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Closed-eye intraocular pressure and eye movement monitoring via a stretchable bimodal contact lens by Xingyi Gan, Guang Yao, Cunbo Li, Yufeng Mu, Maowen Xie, Chenzheng Zhou, Peisi Li, Qiwei Dong, Ke Chen, Kangning Zhao, Min Gao, Taisong Pan, Fang Lu, Dezhong Yao, Peng Xu, Yuan Lin

“…Ex vivo and in vivo MEM monitoring, based on composition-optimized magnetic interlayer film, demonstrated exceptional accuracy (≥97.25%) with eyes open and closed, surpassing existing methods. …”
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Gut virome dysbiosis impairs antitumor immunity and reduces 5-fluorouracil treatment efficacy for colorectal cancer by Hui Huang, Hui Huang, Ying Yang, Xiaojiao Wang, Xiaojiao Wang, Biao Wen, Biao Wen, Xianglan Yang, Wei Zhong, Wei Zhong, Qiurong Wang, Qiurong Wang, Feng He, Feng He, Jun Li, Jun Li

“…In this study, we investigated the impact of antiviral (AV) drug-induced gut virome dysbiosis on the efficacy of 5-FU in CRC treatment.MethodsUsing a subcutaneous CRC mouse model, we assessed tumor growth and immune responses following AV treatment, fecal microbiota transplantation (FMT), and 5-FU administration.ResultsAV therapy reduced the abundance of gut DNA and RNA viruses, leading to accelerated tumor growth, shortened survival, and diminished chemotherapy efficacy. …”
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Mesoscopic analysis and prediction of in-situ effect in FFF 3D printing CFRP/GFRP by Xiang Yu, Pai Peng, Tian-Yun Yao, Yu Zhao, Yong-Jun Zhou, Yuan Jing

“…In terms of numerical prediction, this work refines the traditional empirical formula to account for the specific characteristics of FFF 3D printing composites. As a result, the improved model achieves regression values of 0.88 (CFRP) and 0.72 (GFRP) for transverse in-situ tensile strength, and 0.99 (CFRP) and 0.98 (GFRP) for in-situ shear strength, respectively.…”
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Impact of <i>Schistosoma mansoni</i> Infection on the Gut Microbiome and Hepatitis B Vaccine Immune Response in Fishing Communities of Lake Victoria, Uganda by Yan Wang, Ariana K. Waters, Geofrey Basalirwa, Ali Ssetaala, Juliet Mpendo, Annemarie Namuniina, Emily Keneema, David Kiiza, Jacqueline Kyosiimire-Lugemwa, Yunia Mayanja, Brenda Okech, Sylvia Kiwuwa-Muyingo

“…We investigated its potential impact on Hepatitis B (Hep B) vaccine responses and its role in mediating the association between the gut microbiome and long-term effectiveness of the vaccine. Methods: Participants were tested for <i>S. mansoni</i> infections at baseline and received the Hep B vaccine at baseline, month 1, and month 6. …”
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Explaining and Analyzing the Effect of Brand Value Components on Medical Tourism Development: A Case Study of Ahvaz Metropolis by Majid Goodarzi

“…To achieve this, the collected data were coded and entered into the SPSS version 25 and AMOS version 24 software, both of which are designed for structural equation modeling. The results from the first-order confirmatory factor analysis indicated that the composite reliability values and the Average Variance Extracted (AVE) for all components—perceived quality, brand identity, brand image, brand loyalty, and brand awareness—were satisfactory, confirming both reliability and convergent construct validity. …”
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Progression to fibrosis and hepatocellular carcinoma in DEN CCl4 liver mice, is associated with macrophage and striking regulatory T cells infiltration by Ananya Ajith, Jonathan Evraerts, Caroline Bouzin, Davide Brusa, Makram Merimi, Mehdi Najar, Mehdi Najar, Françoise Smets, Etienne Sokal, Mustapha Najimi

“…This study investigates immune dysregulation that occurs during the progression of CLD to HCC by delineating changes in immune cell composition and distribution within the liver microenvironment.MethodsMice were injected with Diethylnitrosamine (DEN) at 4 weeks of age, followed by continuous tri-weekly injections of carbon tetrachloride (CCl4) for 6 and 21 weeks to induce liver fibrosis and HCC. …”
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Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis by Siqi Ye, Siqi Ye, Jingwen Wang, Jingwen Wang, Feng Luo, Feng Luo, Jinjing Jia, Jinjing Jia, Xiumei Mo, Xiumei Mo, Dacan Chen, Dacan Chen

“…However, their potential associations and mechanisms remain unclear.MethodsThis study used antibiotics to construct a mouse model to analyze the performance of AD mice after gut microbiota destruction. 16S rRNA amplicon sequencing combined with HM700 high-throughput metabolomics was used to characterize differential microbial components and key metabolites in fecal specimens of AD murine models. …”
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Evaluation of the immunomodulatory effects of a novel synbiotic made of combined use of probiotic-prebiotic-Chinese traditional herbs by Deshan Ning, Yiru Huang, Yulong Zhou, Hongwei Zhao, Wenlei Nie, Yu Zheng, Xiaojun Huang

“…Commercially available probiotics were used to investigate the immunomodulatory functions and potential mechanisms associated with the combination of Chinese medicinal herbs and prebiotics as carbon substrates. Methods: The immunomodulatory effect of the synbiotic will be assessed by measuring indicators such as body weight, organ index, immunoglobulins, cytokines, splenic lymphocyte proliferation status, NK cell cytotoxicity and gut microbiota. …”
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Developing the IDCaRe team: an integrated and culturally-affirming approach to improving health engagement for HIV-positive veterans by James Michael Brennan, Madison B. Bailey, William Hua

“…Objective At San Francisco VA Health Care System, the Infectious Disease Care and Resilience (IDCaRe) team was established to improve outcomes for Veterans with acute needs or persistent difficulties in care delivery and efficacy. Method A five-step model to address complex needs in HIV care was adapted from existing literature and evidence base, combined with a culturally-aligned, interdisciplinary care orientation. …”
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Characteristics of the gut virome in patients with premalignant colorectal adenoma by Pan Zhang, Xiaofeng Tuo, Jiong Jiang, Yue Zhang, Juhui Zhao, Chengzhao Deng, Gang Zhao, Yan Cheng, Lingqin Song, Yan Yang, Ruochun Guo, Huan Zhang, Hongli Zhao, Shiyang Ma, Lu Li, Haitao Shi

“…., bacteriome, mycobiome, and virome) characteristics of colorectal cancer have been extensively studied, yet there is still an insufficient description of the microbiota features in its early-stage, colorectal adenoma, particularly in the gut virome aspect. Methods Based on the Metagenomic Gut Virus catalogue (MGV) containing 54,118 non-redundant gut viral genomes, this study characterized the virome composition and diversity using publicly available metagenomic sequencing data from 419 individuals with premalignant colorectal adenoma and 552 healthy controls. …”
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Fecal profiling reveals a common microbial signature for pancreatic cancer in Finnish and Iranian cohorts by Heidelinde Sammallahti, Sama Rezasoltani, Satu Pekkala, Arto Kokkola, Hamid Asadzadeh Agdaei, Mehdi Azizmohammad Looha, Reza Ghanbari, Farhad Zamani, Amir Sadeghi, Virinder Kaur Sarhadi, Marja Tiirola, Pauli Puolakkainen, Sakari Knuutila

“…The inadequacy of current screening methods has prompted investigations into stool-based assays and microbial classifiers as potential early detection markers. …”
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Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation by Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo

“…This study aimed to examine the molecular mechanisms underlying the involvement of NSUN2 in immune evasion and metabolic reprogramming of HCC. Methods Single‐cell transcriptomic sequencing was applied to examine cellular composition changes, particularly immune cell dynamics, in HCC and adjacent normal tissues. …”
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Gender and cultural aspects of brucellosis transmission and management in Nakasongola cattle corridor in Uganda. by Christine Tricia Kulabako, Stella Neema, Lesley Rose Ninsiima, Jörn Klein, Lydia Namakula Nabawanuka, James Muleme, Javier Sánchez Romano, Peter Atekyereza

“…Data were collected using face -to -face interviews with an interview guide that was structured using the Socio Ecological Model of Human Behaviour framework (SEMHB) constructs. …”
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