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4201
Interpretable machine learning excavates a low-alloyed magnesium alloy with strength-ductility synergy based on data augmentation and reconstruction
Published 2025-06-01“…The data reconstruction method reorganizes and transforms the original data to extract more representative features, significantly improving the model's generalization ability and prediction accuracy, with a coefficient of determination (R2) of 95.9 % for the ultimate tensile strength (UTS) model and a R2 of 95.3 % for the elongation-to-failure (EL) model. …”
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4202
Coupling Coordination Degree between New Urbanization and Eco-Environment in Shaanxi, China, and Its Influencing Factors
Published 2021-01-01“…On this basis, the coordination coupling between new urbanization and eco-environment in Shaanxi and its key factors were evaluated and analyzed, using composite index method, relative development level model, coupling degree model, and coordination coupling degree (CCD) model. …”
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4203
Development and Characterization of Dual-Loaded Niosomal Ion-Sensitive In Situ Gel for Ocular Delivery
Published 2024-12-01“…The optimal composition was included in a gellan gum-based in situ gel, and the antimicrobial activity, in vitro toxicity in a suitable corneal epithelial model (HaCaT cell line), and antioxidant potential of the hybrid system were further assessed. …”
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4204
Development of metacognitive skills of university students as a resource for understanding texts in the learning process
Published 2025-06-01“…The following indicators were used to ascertain students' mastery of the methods of understanding hypertext texts: the ability to formulate a problem; the ability to complete the problem condition; the construction of a semantic context in relation to a paradoxical, "impossible" situation; the measure of openness of individual cognitive position as an indicator of arbitrary intellectual control; the features of the cognitive style impulsiveness/reflexivity, which characterises the level of involuntary intellectual control in conditions of uncertain choice; the composition of one's own hypertext with hyperlinks as a result of mastery of a particular section of a scientific discipline. …”
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4205
VEGF-B-mediated myofiber types involved in high-fat diet-induced hyperglycemia through PKA-NFATs signaling pathway
Published 2025-07-01“…Notably, skeletal muscle fiber-type composition is closely linked to insulin resistance. …”
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4206
Research and Development of Organic Phase Change Materials for Cool Thermal Energy Storage
Published 2016-01-01“…It is pointed out that performance characteristics, theoretical model of heat transfer, phase transition mechanism and composite technology of PCMs should be focused on, and organic composite phase change thermal storage material is the key development direction of organic phase change materials in the future.…”
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4207
Experimental and Simulation Research Progress on the Solidification Structure Evolution of High Chromium Cast Iron
Published 2025-06-01“…Furthermore, the application of simulation techniques—including thermodynamic modeling, phase-field method, cellular automata, and finite element analysis—is discussed in detail, highlighting their roles in revealing the mechanisms of microstructural evolution. …”
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4208
Typology of the "Internal Form-Structure" Drawing upon Argan\'s Formal Approach (Case Study: Historical Bridge-Caravanserai in Iran)
Published 2020-12-01“…Using a descriptive - analytical method, the data were collected through desk and field studies. …”
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4209
Advancements in materials and fabrication techniques for microneedle ocular patch: a comprehensive review
Published 2025-06-01“…Despite significant research in formulation studies and animal models, the clinical efficacy and safety of MNs in ophthalmology require further investigation. …”
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4210
Gut microbiome changes and cancer immunotherapy outcomes associated with dietary interventions: a systematic review of preclinical and clinical evidence
Published 2025-07-01“…In our systematic review, we explored how dietary habits correlate with therapeutic responses in cancer patients and cancer mouse models undergoing immunotherapy. Methods A systematic review was conducted using search terms: “cancer”, “immunotherapy”, “diet”, and “microbiome”, from Medline, Web of Science, Scopus, and Cochrane Library databases. …”
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4211
Artificial intelligence applied to the study of human milk and breastfeeding: a scoping review
Published 2024-12-01“…This study aimed to identify and synthesize the current information on the use of AI in the analysis of human milk and breastfeeding. Methods A scoping review was conducted according to the PRISMA Extension for Scoping Reviews guidelines. …”
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4212
Experimental and Numerical Study of the Jib Connection Frame of a Wheeled Crane
Published 2025-04-01“…First, the beam and solid finite element model of the connecting frame were constructed, and the ultimate load-carrying capacity and failure mode of the structure were determined using the finite element method, according to which the strain gauge array test program was designed. …”
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4213
Intervention effect and mechanism of Dracocephalum moldavica L. extract on bleomycin-induced pulmonary fibrosis in rats
Published 2024-12-01“…ObjectiveTo elucidate the targets and potential mechanism underlying the anti-pulmonary fibrosis efficacy of Dracocephalum moldavica L. extract by employing an amalgamation of network pharmacology and empirical verification. MethodsThe chemical composition of the extract of Dracocephalum moldavica L. was retrieved with the help of China National Knowledge Infrastructure (CNKI) and Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP). …”
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4214
Calculating slope gradient variations in the submarine landforms by R and Python statistical libraries
Published 2019-12-01“…The results show differences in the gradient slope between various segments of the Mariana Trench located in four tectonic plates: Mariana, Caroline, Pacific and Philippine Sea, performed by statistical data modelling. Programming codes and snippets are presented for repeatability of the methods in similar research tasks.…”
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4215
Mechanochemical‐Induced Swelling–Activation of a Gastric‐Deployable 4D‐Printed Polypill Inspired by Natural Hygromorphic Actuators
Published 2025-04-01“…Gastroretentive drug delivery systems can improve adherence in patients with chronic diseases (CDs), but current options lack dose flexibility and involve complex fabrication methods. Inspired by the hygroscopic deformation observed in multilayered pine cone scales, wherein hydration of the outer active layer induces cone closure, a one‐step fabrication method of a personalized 4D‐printed water‐actuated four‐arm polypill is demonstrated in this study. …”
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4216
Gut microbiome dysbiosis accelerates osteoarthritis progression by inducing IFP-SM inflammation in “double-hit” mice
Published 2025-07-01“…Furthermore, it elucidates the role of gut microbiota (GMB) dysbiosis in driving OA progression. Methods A refined “double-hit” murine model was developed to explore this relationship. …”
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4217
Detecting fish community structure in open waters using environmental DNA: a case study from the central South China Sea
Published 2025-03-01“…Monitoring fish diversity in open ocean environments presents substantial challenges, particularly due to the limitations of traditional sampling methods such as trawling, which are costly, labor-intensive, and ineffective for deeper water layers. …”
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4218
Key considerations based on pharmacokinetic/pharmacodynamic in the design of antibody-drug conjugates
Published 2025-01-01“…However, complexity of its structural composition poses a greater difficulty for drug design studies.ObjectivesPharmacokinetic/pharmacodynamic (PK/PD) based consideration of ADCs has increasingly become a hot research topic for optimal drug design in recent years, providing possible ideas for obtaining ADCs with desirable properties.MethodsFrom the assessment of the ADC action process based on PK/PD, we introduce the main research strategies of ADCs. …”
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4219
Bioinformatics analysis of ferroptosis-related biomarkers and potential drug predictions in doxorubicin-induced cardiotoxicity
Published 2025-04-01“…Further validation of the expression levels of key genes were conducted through the establishment of a cell damage model. Constructed an mRNA-miRNA-lncRNA network diagram, and performed immune cell composition analysis using CIBERSORT. …”
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4220
Urinary Hippuric Acid as a Sex-Dependent Biomarker for Fruit and Nut Intake Raised from the EAT-Lancet Index and Nuclear Magnetic Resonance Analysis
Published 2025-05-01“…<b>Background/Objectives</b>: Assessing nutrient intake is essential for understanding body homeostasis and diet–health interactions. Traditional methods, such as dietary questionnaires and quality indices, are limited by subjectivity and variability in food composition tables. …”
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