Mechanisms of microbial-gut-brain axis modulation by electroconvulsive therapy in the treatment of depression by Jiaming Ji, Jinyan Guo, Jirong Yang, Siyang Zeng, Xue Han, Ziqing Hei, Weifeng Yao, Chaojin Chen

“…Methods A depression model in mice was established using chronic unpredictable mild stress. …”
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Response surface optimization for cadmium biosorption onto the pre-treated biomass of red algae Digenia simplex as a sustainable indigenous biosorbent by Sedky H.A. Hassan, Maryam M. Alomran, Nada I.A. Alsugiran, Mostafa Koutb, Hassan Ahmed, Mustafa A. Fawzy

“…The objective of this study was to remove cadmium (Cd2+) from aquatic environments using red macroalgae Digenia simplex pretreated with calcium chloride (CaCl2) (DSC). Methods Batch adsorption studies were carried out to evaluate the individual impacts of adsorbent-metal contact time, cadmium concentration, and temperature on the cadmium removal efficiency and biosorption capacity. …”
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Development and characterization of a novel immortalized human vaginal fibroblast cell line for advanced applications in reproductive health by Leong Chi Cheng, Shuoming You, Tingting Ren, Junjun Qiu, Keqin Hua

“…Abstract Background Reproductive health issues related to the vagina, face significant challenges due to the lack of standardized research models. Vaginal fibroblasts, which constitute approximately 55% of the vaginal wall’s cellular composition, are crucial for tissue repair, remodelling, and reproductive health. …”
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Effect of cigarette smoke exposure and cessation on regional diffusion properties in rat intervertebral discs by Joshua Kelley, Nathan Buchweitz, Avery Madden, Hongming Fan, Glenn Hepfer, Michael Kern, Danyelle M. Townsend, Tong Ye, Hai Yao, Yongren Wu

“…This study aimed to address this knowledge gap through a quantitative assessment of IVD structural composition and diffusion properties using a Sprague–Dawley rat model. …”
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Therapeutic potential of atorvastatin in ischemic stroke: an investigation into its anti-inflammatory effect by targeting the gut-brain axis by Liuzhu Chen, Linpei Zhuo, Jie Zheng, Xiaoyun Sun, Jing Sun, Jiaming Liu

“…Thus, this study aimed to explore the relationship between atorvastatin, gut microbiota and IS through animal experiments, clinical trials and Mendelian randomization (MR) analysis. Methods Male mice were induced with bilateral common carotid artery occlusion (BCCAO) to establish an IS animal model, and then intragastrically treated with atorvastatin. …”
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Paederia scandens extract alleviates obesity via modulating the gut microbiota and serum metabolome disorder by Yuanyuan Yang, Jinglei Si, Jiayuan Mo, Jin Li, Bin Pan, Yi Pan, Lihe Jiang, Decai Wang, Xueping Feng

“…There is an urgent need to identify more affordable methods to combat this condition. Paederia scandens (PS), a cost-effective herbal remedy widely used in China for treating inflammation and pain, shows potential in this regard. …”
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Tadalafil Enhances the Therapeutic Efficacy of Mesenchymal Stem Cells-Derived Exosomes in Pulmonary Hypertension by Upregulating miR-29a-3p by Liu Y, He C, Zhong Q, Shi X, Li H, Fu G, Guo L, Zhao C, Tian L, Li X, Jiao X, Shan L

“…This study aimed to identify an intervention strategy to enhance the efficacy of mesenchymal stem cell exosomes in treating PH.Methods: Exosomes were isolated from control MSC and tadalafil-pretreated MSCs. …”
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Willingness to use a drug checking service for cannabis and cannabis-based products: results from an online survey of people who regularly use cannabis in France by Martin Bastien, Salim Mezaache, Cécile Donadille, Laélia Briand Madrid, Maëla Lebrun, Victor Martin, Perrine Roux

“…Abstract Introduction As cannabis is illegal in France, there is no regulation of the quality or composition of cannabis products on the illicit market. …”
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Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice by Yong Lai, Yong Lai, Qifan Zhang, Maohan Xu, Xiurong Guo, Quan Zhou, Qiuyu Liu, Huiling Deng, Can Song

“…Subsequently, by comprehensively evaluating multiple parameters including the body weight, dietary patterns, cecal histomorphological characteristics, intestinal microbiota composition, concentrations of short-chain fatty acids (SCFAs), and the levels of inflammatory factors in the antibiotic-associated diarrhea (AAD) model animals, we delved into both the action mechanisms of these polysaccharides and their impacts on the intestinal flora and metabolites within C57BL/6J mice.ResultsOur results showed that DIPY effectively ameliorated AAD in mice by modulating the intestinal flora, increasing microbial diversity, the Shannon and Ace index was significantly higher in the DIPY group than in the NR group after the DIPY intervention (p < 0.001). …”
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Discussions on the Adsorption Behaviors Affected by the Differences Between Graphene Oxide and Graphene Grafted by Chitosan by Chin-Chun Chung, Hua-Wei Chen, Jin-Lin Han, Hung-Ta Wu

“…The Toth adsorption isotherm model was used to fit the adsorption uptake, and the average deviation was about 1.36%.…”
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Applicability of Machine Learning and Mathematical Equations to the Prediction of Total Organic Carbon in Cambrian Shale, Sichuan Basin, China by Majia Zheng, Meng Zhao, Ya Wu, Kangjun Chen, Jiwei Zheng, Xianglu Tang, Dadong Liu

“…This study introduces three key innovations to address these challenges: (1) A Dynamic Weighting–Calibrated Random Forest Regression (DW-RFR) model integrating high-resolution Gamma-Ray-guided dynamic time warping (±0.06 m depth alignment precision derived from 237 core-log calibration points using cross-validation), Principal Component Analysis-Deyang–Anyue Rift Trough Shapley Additive Explanations (PCA-SHAP) hybrid feature engineering (89.3% cumulative variance, VIF < 4), and Bayesian-optimized ensemble learning; (2) systematic benchmarking against conventional ΔlogR (R² = 0.700, RMSE = 0.264) and multi-attribute joint inversion (R² = 0.734, RMSE = 0.213) methods, demonstrating superior accuracy (R² = 0.917, RMSE = 0.171); (3) identification of Gamma Ray (r = 0.82) and bulk density (r = −0.76) as principal TOC predictors, contrasted with resistivity’s thermal maturity-dependent signal attenuation (r = 0.32 at Ro > 3.0%). …”
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The impact of the international rice genebank’s (IRG) on rice farming in Bangladesh by Donald Villanueva, Yuji Enriquez, Grace Lee Capilit

“…This study aimed to map the impact pathways of IRG germplasm transfers to Bangladesh, evaluate the genetic contribution of IRG germplasms to rice productivity of farmers, and compute the equivalent economic benefit. Methods Impact pathway analysis was conducted to map the IRG’s germplasm transfer for varietal improvement and seed dissemination of improved rice varieties in Bangladesh using the information collected from key informant interviews. …”
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Characteristics of adaptive immune effectors involved in the secondary xenogeneic immune response to human melanoma cells by N. A. Persiyantseva, A. A. Kalinina, M.  A. Zamkova, L. M. Khromykh, D. B. Kazansky

“…To assess the prospects for using xenogeneic immunizations to generate tumor-specific memory T cells and identify their TCRs suitable for adoptive immunotherapy, we studied the dynamics of the secondary xenogeneic response in a model of induction of an immune response in mice to human melanoma cells.Materials and methods. …”
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Effect of different dialysis duration on the prognosis of peritoneal dialysis-associated peritonitis: a single-center, retrospective study by Qichen Liang, Huiping Zhao, Bei Wu, Qingyu Niu, Lixia Lu, Jie Qiao, Chuncui Men, Yuting He, Xinxin Chu, Li Zuo, Mei Wang

“…Herein, we investigated the clinical characteristics and treatment outcomes of PD peritonitis in patients with different PD durations.Methods All peritonitis episodes from January 2007 to December 2020 at Peking University People’s hospital PD center were retrospectively analyzed and divided into the long-dialysis duration (≥60 months, LDD) and short-dialysis duration (<60 months, SDD) groups. …”
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NeXtMD: a new generation of machine learning and deep learning stacked hybrid framework for accurate identification of anti-inflammatory peptides by Chengzhi Xie, Yijie Wei, Xinwei Luo, Huan Yang, Hongyan Lai, Fuying Dao, Juan Feng, Hao Lv

“…Benchmark evaluations demonstrate that NeXtMD outperforms current state-of-the-art methods on multiple performance metrics. Moreover, NeXtMD maintains strong generalization capabilities when applied to unseen peptide sequences, showing its robustness and scalability. …”
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ARHGAP25: a novel player in the Pathomechanism of allergic contact hypersensitivity by Domonkos Czárán, Péter Sasvári, Kende Lőrincz, Krisztina Ella, Virág Gellén, Roland Csépányi-Kömi

“…ARHGAP25 altered cytokine composition in the sensitization and elicitation phase of the disease. …”
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Patterns of student socio-emotional development and teacher-student-relationship-quality for high-school students with and without special educational needs: a multigroup latent tr... by Giuliana Pastore, Wassilis Kassis, André Kunz, Reto Luder

“…In addition, we tested whether having SEN or being in a high vs. low selective schools make a difference for the composition of each profile.MethodsTo this end, latent class (LCA) and latent transition analyses (LTA) were conducted with longitudinal data from a three-waves (2019, 2020, and 2021) questionnaire study with N = 807 junior high school students in Switzerland.ResultsFour similar patterns could be identified in both low and high selective schools: “happy” students, feeling generally well (emotionally, socially and cognitively) and well-supported by teachers; “unhappy” students, not feeling well and not supported, “teacher-oriented” students, not feeling well but well-supported by teachers, and finally “unstable” students, drastically changing their perceptions of wellbeing, inclusion and self-concept over time but consistently feeling less reliance on teachers. …”
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Comparative efficacy of transdermal forms for alopecia therapy by U. V. Nogaeva, D. Yu. Ivkin, G. A. Plisko, E. V. Flisyuk, V. E. Kovanskov, Yu. G. Shtyrlin, K. O. Sidorov

“…Investigate the possibility of applying the original substance Y in several dosage forms for the treatment of alopecia in comparison with reference drugs: minoxidil and burdock oil.Materials and methods. The research subject was the original substance Y, for which several dosage forms were made: gel, alcohol and oil compositions. …”
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Impact of submicron Nb_{3}Sn stoichiometric surface defects on high-field superconducting radiofrequency cavity performance by Sarah A. Willson, Aiden V. Harbick, Liana Shpani, Van Do, Helena Lew-Kiedrowska, Matthias U. Liepe, Mark K. Transtrum, S. J. Sibener

“…The SRF community currently lacks a predictive model that can explain the impact of chemical and morphological properties of Nb_{3}Sn defects on vortex nucleation and maximum accelerating gradients. …”
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Extraction of Rare Earth Elements (REE) from End-of-Life NiMH Battery Electrode Powders Using Deep Eutectic Solvent (DES) by Francesca Pagnanelli, Pier Giorgio Schiavi, Marco Colasanti, Pietro Altimari

“…In this study, original data are presented on the extraction of REEs from electrode powders of NiMH batteries pre-treated through physical methods in a cryo-mechanical pilot plant. The electrode powder was characterized for its chemical composition and subsequently subjected to extraction using a DES based on choline chloride and lactic acid (with a molar ratio of 1:2). …”
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