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4141
Impeding Quorum Sensing Among the Intestinal Microbiota Impacts the Metastatic Rate of Colorectal Cancer
Published 2025-06-01“…Aims Here, we hypothesized that microbial communication, mediated through quorum sensing (QS), was a critical component regulating microbial functions related to cancer progression and metastasis. Materials & Methods To test this, male and female C57BL/6 mice were injected with organoids modeling aggressive colon cancer (CRC), carrying mutations in Apc, Kras, p53, and Smad4. …”
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4142
AI-Driven predicting and optimizing lignocellulosic sisal fiber-reinforced lightweight foamed concrete: A machine learning and metaheuristic approach for sustainable construction
Published 2025-06-01“…The optimized composition achieved a tensile strength of 4.16 MPa, representing a 9.5 % enhancement compared to conventional experimental methods, which yielded 3.8 MPa. …”
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4143
Free Vibrations and Impact Resistance of a Functionally Graded Honeycomb Sandwich Plate
Published 2021-01-01“…The natural frequencies of the graded honeycomb sandwich plate are obtained by both the Navier method from the governing equation and the finite element model. …”
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4144
Lactobacillus reuteri DSM 17,938 ameliorates LPS-induced depression-like and anxiety-like behaviors by modulating gut microbiota and brain metabolic function
Published 2025-08-01“…The purpose of this study is to validate the effects of L. reuteri DSM 17,938 and preliminarily explore its underlying antidepressant and anxiolytic mechanisms, thereby providing a general direction for researching the targets of its antidepressant and anxiolytic effects. Methods The depressive mouse model induced by lipopolysaccharide (LPS) was intervened with L. reuteri DSM 17,938 (5 × 109 cfu/ml), and behavioral experiments were conducted to evaluate the therapeutic effects of the probiotic on depression. …”
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4145
Reduced Birth Weight, Decreased Early-Phase Insulin Secretion, and Increased Glucose Concentrations after Oral Glucose Tolerance Test in Japanese Women Aged 20 Years with Family Hi...
Published 2020-01-01“…We tested the hypothesis that family history of type 2 diabetes (FHD) is associated with reduced birth weight and reduced insulin secretion later in life. Materials and Methods. Birth weight, body composition by whole-body dual-energy X-ray absorptiometry, and homeostasis model assessment-insulin resistance were compared between Japanese women aged 20 years with positive (n=73) and negative (n=258) FHD. …”
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4146
Effects of distiller’s dried grains with solubles on enteric methane emissions in dairy and beef cattle: a meta-analysis
Published 2024-12-01“…This study utilized a multilevel random-effects meta-analysis to assess the impact of DDGS inclusion in cattle diets on CH4 production and yield.MethodsThe literature search was conducted on 23 July 2024. …”
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4147
Examining the dietary contributions of lipids to pancreatic cancer burden (1990–2021): incidence trends and future projections
Published 2025-02-01“…This study addresses this gap through a comprehensive analysis of PC incidence trends from 1990 to 2021, with a specific focus on associations with age, dietary patterns, and socio-demographic determinants. Methods The data utilized in this study were obtained from the 2021 Global Burden of Disease (GBD) results database, updated on May 16, 2024. …”
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4148
Artificial intelligence analysis of thermal energy for convectively heated ternary nanofluid flow in radiated channel considering viscous dissipations aspects
Published 2025-02-01“…The use of AI in creating the simulations is more accurate for prediction than traditional numerical methods with an improved MSE of up to 10−14 through the Python model. …”
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4149
Study on the Influence and Mechanism of Resveratrol on Cognitive Impairment in Chronic Kidney Disease Rats Through Regulating Gut Microbiota and the TLR4/NFκB Pathway
Published 2025-05-01“…Binbin Shao,1 Yanfei Nong,1 Yongshuang Lin,2 Yan Meng,1 Yi Zhou,1 Meiying Huang,3 Feifan Huang,3 Jie Wang3 1Graduate School, Youjiang Medical University for Nationalities, Baise, Guangxi, 533000, People’s Republic of China; 2The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning, 530000, People’s Republic of China; 3Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, Guangxi, 533000, People’s Republic of ChinaCorrespondence: Jie Wang, Email yyfywj@126.comObjective: To investigate the mechanism by which resveratrol (Res) ameliorates cognitive impairment (CI) in chronic kidney disease (CKD) rats through modulation of gut microbiota and suppression of inflammation.Methods: A CKD model was established in rats via two intravenous injections of doxorubicin (4 mg/kg, 2 weeks apart). …”
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4150
A comprehensive analysis of the tryptophan metabolism-related gene signature to predict the prognosis of esophageal squamous cell carcinoma based on multi-omics
Published 2025-08-01“…Least absolute shrinkage and selection operator (LASSO) and univariate Cox regression were used to select prognostic TrpGs and construct a risk model. The overall survival, immune infiltration, checkpoint expression, drug sensitivity, and microbiota composition between high- and low-risk groups were evaluated. …”
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4151
Designing the Forest of Tomorrow: Generating Virtual Trees with Adversarial Autoencoders
Published 2025-07-01“…By leveraging remote sensing data, we aim to capture individual tree features and characteristics accurately, linking them to dynamic simulations of forest structures and composition. Employing a deep learning approach, we train models on existing 3D scanned data to produce diverse and realistic visual representations of specific tree species. …”
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4152
Observations of Optical Properties and Chlorophyll-a Concentration in Qiandao Lake Using Shipborne Lidar
Published 2024-12-01“…Lidar technology is increasingly applied to the inversion of oceanic biological parameters and optical properties based on empirical and semi-empirical bio-optical models. However, these models cannot be directly applied to inland waters due to their complex composition, and research on the biological parameters and optical properties of inland waters remains limited. …”
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4153
Determinants of Sustainability Reporting in the Romanian Banking Sector
Published 2025-05-01“…This paper investigates the determinants of Sustainable Development Goals (SDG) reporting in the Romanian banking sector over an extended time horizon (2017-2023), employing a mixed-method approach that combines content analysis, fixed-effects regression, and regression trees. …”
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4154
Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment
Published 2025-07-01“…Its role in disease progression has been studied in ovarian cancer cells; however, its role in the ovarian TME is less understood.MethodsIn this study, for the first time, we assessed the therapeutic potential of novel covalent irreversible small molecule TG2 inhibitors in xenograft models of ovarian cancer. …”
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4155
UV-C and Nanomaterial-Based Approaches for Sulfite-Free Wine Preservation: Effects on Polyphenol Profile and Microbiological Quality
Published 2025-01-01“…Controlling the microorganisms employed in vinification is a critical factor for successful wine production. Novel methods aimed at lowering sulfites used for wine stabilization are sought. …”
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4156
Advancing perovskite solar cells: Optical characterization and performance enhancement via spectroscopic ellipsometry
Published 2025-06-01“…Specifically, this review examines the analytical approaches for analyzing the perovskite properties, selecting theoretical optical models and data fitting methods, extracting key optical constants, and interpreting SE measurements. …”
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4157
Mesenchymal stromal cell-derived extracellular vesicles as nanotherapeutics for concanavalin a-induced hepatitis: modulating the gut‒liver axis
Published 2025-01-01“…However, their effects on autoimmune hepatitis (AIH) are not yet well understood. Methods and results In this study, we utilized a well-established concanavalin A (Con A)-induced fulminant hepatitis mouse model to investigate the effects of MSC-EVs on AIH. …”
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4158
Software-Based Transformation of White Light Endoscopy Images to Hyperspectral Images for Improved Gastrointestinal Disease Detection
Published 2025-06-01“…Conventional diagnostic methods employing white light imaging (WLI) in wireless capsule endoscopy (WCE) provide limited spectrum information, therefore influencing classification performance. …”
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4159
Innovative Valorization of Wood Panel Waste into Activated Biochar for Efficient Phenol Adsorption
Published 2025-07-01“…The biochar’s physicochemical properties, including surface area, pore volume, and elemental composition, were characterized using advanced methods, including BET analysis, elemental analysis, and adsorption isotherm analysis. …”
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4160
Research on Malodor Component Identification Based on Sensor Array
Published 2025-06-01“…Experimental results demonstrate that the proposed IED-CNN-LSTM model outperforms conventional methods significantly in both prediction accuracy and long-term stability. …”
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