Proteomic and Targeted Lipidomic Analyses of Fluid and Rigid Rubber Particle Membrane Domains in Guayule by Joshua J. Blakeslee, Eun-Hyang Han, Yun Lin, Jinshan Lin, Seema Nath, Liwen Zhang, Zhenyu Li, Katrina Cornish

“…Using guayule (<i>Parthenium argentatum</i>) as a model rubber-producing species, we optimized methods to isolate RP unilamellear membranes and then a subset of membrane microdomains (detergent-resistant membranes) likely to contain protein complexes such as RTase. …”
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Abnormality in field physical test predicts a reduced quadriceps strength in patients with hip- or knee-osteoarthritis. A prospective observational study. by Quentin Fanget, Anargyros Verdilos, Samuel Adelou, Vivien Reynaud, Stéphane Boisgard, Stéphane Descamps, Bruno Pereira, Ruddy Richard, Emmanuel Coudeyre, Frédéric Costes

“…<h4>Objectives</h4>To find out the determinants of a reduced quadriceps strength and to establish a score to screen for it.<h4>Methods</h4>In an observational prospective study, we evaluated patients presenting with an unilateral knee (KOA) or a hip (HOA) osteoarthritis before a scheduled arthroplasty. …”
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ASSESSMENT OF THE IMPACT OF VANILLIN AND QUERCETIN ON THE DEGREE OF FEED DIGESTABILITY AND THE RUMEN MICROBIOME OF CATTLE by Ludmila V. Vlasenko, Kseniya N. Atlanderova, Galimzhan K. Duskaev

“…The goal of the study was to evaluate the effect of vanillin and quercetin on the degree of digestibility of feed and the microbiome of the rumen of cattle. Materials and methods. Object of study: rumen contents of Kazakh white-headed bull calves. …”
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Algorithmization of the problem of videoscopic evaluation of the steel ropes state by Panfilov A.V., Yusupov A.R., Gavrikov M.M., Sinetsky R.M.

“…The paper presents the results of preliminary testing of the developed algorithms and programs, the composition and methods for determining the main indicators for evaluating their effectiveness are proposed.…”
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Healthy Cardiovascular Status Attenuates the Detrimental Association Between Osteosarcopenic Adiposity and Alzheimer's Disease‐Related Dementia: A UK Biobank Cohort Study by Wenxu Wang, Rui Ren, Honghao Yang, Jinguo Jiang, Xingyue Ye, Chenying Wang, Xiang Ji, Wen Li, Yuhong Zhao, Yang Xia, Difei Wang

“…Background Body composition abnormalities are associated with the risk of Alzheimer's disease‐related dementia (ADRD). …”
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Machine learning integrates region-specific microbial signatures to distinguish geographically adjacent populations within a province by Li Luo, Li Luo, Bangwei Chen, Bangwei Chen, Shengyin Zeng, Shengyin Zeng, Yaxin Li, Yaxin Li, Xiaolin Chen, Xiaolin Chen, Jianguo Zhang, Xiangjie Guo, Shujin Li, Lei Ruan, Shida Zhu, Cairong Gao, Cuntai Zhang, Tao Li

“…However, the gut microbiota variations among people residing in different regions within a province remain enigmatic.MethodsShotgun metagenomics sequencing was performed to analyze the gut microbiota of 381 unrelated Chinese Han individuals living in two cities (Wuhan and Shiyan) of Hubei Province. …”
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Approaches to discern if microbiome associations reflect causation in metabolic and immune disorders by Marijana Basic, Dominique Dardevet, Peter Michael Abuja, Silvia Bolsega, Stéphanie Bornes, Robert Caesar, Francesco Maria Calabrese, Massimo Collino, Maria De Angelis, Philippe Gérard, Miguel Gueimonde, François Leulier, Eva Untersmayr, Evelien Van Rymenant, Paul De Vos, Isabelle Savary-Auzeloux

“…We particularly focused on discussing methods available for studying the causality ranging from the usage of gut microbiota transfer, diverse models of metabolic and immune perturbations involving nutritional and chemical factors, gene modifications and surgically induced models, metabolite profiling up to culture-based approached. …”
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Estimating Carbon Biomass Using DNA: Phytoplankton as a Case Study by Lingjie Zhou, Nanjing Ji, Brittany N. Sprecher, Senjie Lin

“…DNA analysis has the potential to profile species composition and estimate species-specific carbon biomass simultaneously. …”
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On possible petrol ignition on М₁, М₁G car catalyst converters surface by A. I. Nedobitkov, V. S. Yakovlev

“…The safety requirements for prevention of fuel ignitions in a motor cabinet of a car have been analyzed during the research.Materials and Methods. Under the conditions of an accredited laboratory specializing in testing automobile fuels and oils, we have carried out the experiments in ignition of K4-class petrol being fed in drops and stream-like fed on a hot surface. …”
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APOE ε4 and exercise interact in a sex‐specific manner to modulate dementia risk factors by Kate E. Foley, Cory A. Diemler, Amanda A. Hewes, Dylan T. Garceau, Michael Sasner, Gareth R. Howell

“…While both APOE ε4 and exercise have been studied extensively, their interactive effects are not well understood. Methods To address this, male and female APOE ε3/ε3, APOE ε3/ε4, and APOE ε4/ε4 mice ran voluntarily from wean (1 month) to midlife (12 months). …”
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Immunotropic effects of Curcuma longa extract as a component of original rectal suppositories in the dynamics of experimental Сrohn’s disease by М. V. Osikov, Е. V. Simonyan, A. E. Bakeeva, O. I. Ogneva

“…The study was performed on 70 Wistar male rats. Crohn’s disease was modeled by introduction of a 50% alcohol solution of trinitrobenzene sulfonic acid (TNBS) per rectum, and verified by clinical and morphological methods. …”
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Evaluation of Evaporative Degradation of Arc Torch Cathodes in Hydrocarbon-Containing Plasmas for Spraying, Thermal Protection Testing and Related Technologies by A. V. Gorbunov, V. A. Gorbunova, O. G. Devoino, G. Petraconi Filho, A. A. Halinouski

“…For this procedure, as the first stage, thermodynamic methods can be used to simulate the composition and properties of reactive C–H–O–N–Ar–Me-systems with variable set of such input parameters as the ratio of components of plasma-forming mixture, its pressure and temperature. …”
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Mesalazine: a novel therapeutic agent for periodontitis via regulation of periodontal microbiota and inhibiting Porphyromonas gingivalis by Yuqi Wang, Yuqi Wang, Jun Ma, Haoyu Wang, Haoyu Wang, Jingzheng Yi, Yuxin Bai, Yuxin Bai, Min Hu, Min Hu, Jiaqing Yan, Jiaqing Yan

“…Given the similarities in their pathogenic factors, this study hypothesized that mesalazine, a key treatment agent for inflammatory bowel disease, could also be effective in managing periodontitis.MethodsThe antimicrobial effect of mesalazine on Porphyromonas gingivalis was investigated in vitro, including observations of morphological changes on the surface of P. gingivalis. …”
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Diagnostic potential of salivary microbiota in persistent pulmonary nodules: identifying biomarkers and functional pathways using 16S rRNA sequencing and machine learning by Xiao Zeng, Qiong Ma, Chun-Xia Huang, Jun-Jie Xiao, Xi Fu, Yi-Feng Ren, Yu-Li Qu, Hong-Xia Xiang, Mao Lei, Ru-Yi Zheng, Yang Zhong, Ping Xiao, Xiang Zhuang, Feng-Ming You, Jia-Wei He

“…Abstract Background The aim of this study was to explore the microbial variations and biomarkers in the oral environment of patients with persistent pulmonary nodules (pPNs) and to reveal the potential biological functions of the salivary microbiota in pPNs. Materials and methods This study included a total of 483 participants (141 healthy controls and 342 patients with pPNs) from June 2022 and January 2024. …”
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<i>Cystoseira spinosa</i> Polysaccharide: A Promising Natural Source for Antioxidant, Pro-Angiogenic, and Wound Healing Applications: In Silico Study by Mouhamed Ayad Berfad, Intissar Kammoun, Marwa Lakhrem, Zakaria Boujhoud, Malek Eleroui, Manel Mellouli, Saadia Makni, Majed Kammoun, Riadh Badraoui, Jean Marc Pujo, Hatem Kallel, Ibtissem Ben Amara

“…Collected off the coast of Alkhoms, Libya, PCS was investigated for its wound-healing and pro-angiogenic properties, addressing the need for natural bioactive compounds in therapeutic applications. <b>Methods:</b> The monosaccharide composition of PCS was analyzed using HPLC-RID, identifying glucuronic acid and xylose as major components. …”
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Machine learning-assisted analysis of serum metabolomics and network pharmacology reveals the effective compound from herbal formula against alcoholic liver injury by Jiamu Ma, Peng Wei, Xiao Xu, Ruijuan Dong, Xixi Deng, Feng Zhang, Mengyu Sun, Mingxia Li, Wei Liu, Jianling Yao, Yu Cao, Letian Ying, Yuqing Yang, Yongqi Yang, Xiaopeng Wu, Gaimei She

“…Nevertheless, the effective compound is challenging to identify due to its intricate composition and multiple targets. Methods An integration machine learning-assisted approach was established, whereby the particular action mechanism and direct target were obtained through the correlation of compounds, targets, and metabolites. …”
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Continuous quality improvement across a South Australian health service and the role it plays in a learning health system: a qualitative study by Mia Bierbaum, Susan Hillier, Louise A. Ellis, Robyn Clay-Williams, Angie Goodrich, Robert Padbury, Peter Hibbert

“…This study evaluated the strengths and challenges of CIP009 implementation from the perspective of participants and deliverers. Methods A qualitative study was conducted in 2023/2024 to evaluate the implementation of CIP009 and 12 associated quality improvement projects. …”
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Self-Nanoemulsifying Drug Delivery System of Morin: A New Approach for Combating Acute Alcohol Intoxication by Mao J, Liu X, Zhang L, Chen Y, Zhou S, Liu Y, Ye J, Xu X, Zhang Q

“…In this study, our aim was to develop a self-nanoemulsifying drug delivery system (SNEDDS) to enhance MOR’s solubility and bioavailability, evaluate its anti-AAI effects, and investigate the underlying mechanism.Methods: The composition of MOR-loaded self-nanoemulsifying drug delivery system (MOR-SNEDDS) was determined by constructing pseudo-ternary phase diagrams, and its formulation proportion was optimized using the Box-Behnken design. …”
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Synergistic treatment of sodium propionate and Sishen Pill for diarrhea mice with kidney-yang deficiency syndrome by Meifang Guo, Jiaxin Di, Zhijun Lei

“…ObjectiveThis study aimed to investigate the therapeutic effects of sodium propionate in combination with Sishen Pill in the treatment of diarrhea with kidney-yang deficiency syndrome in mice, with a focus on its influence on intestinal microbiota, enzyme activity, and associated therapeutic outcomes.MethodsA model of diarrhea with kidney-yang deficiency syndrome was established via adenine combined with Folium sennae administration. …”
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The dietary inflammation index and body mass index mediate the association between the dietary index for gut microbiota and sarcopenia in older women: evidence from NHANES 2011–201... by Xiaoyan Zhang, Liangzhi Wu, Yutian He, Shuyao Zhang, Wenfeng Hua, Wenfeng Hua

“…BackgroundThe dietary index of gut microbiota (DI-GM) was developed to assess dietary quality by reflecting the diversity of the gut microbiota composition. This study examined the relationship between DI-GM and sarcopenia risk and evaluated the potential moderating effects of diet-related factors on sarcopenia risk in adult individuals.MethodsThis cross-sectional study included 8,872 adults from the National Health and Nutrition Examination Survey (NHANES) database between 2011 and 2018. …”
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