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4041
Features of the implementation of the financial and legal status of municipalities, included in urban agglomerations
Published 2020-04-01“…The formation of urban agglomerations is called one of the possible forms of regulation of intergovernmental relations. The Russian model for the development of agglomerations so far follows the path of allocating inter-budget transfers from the federal budget.Agglomeration development is possible only with the interaction of all municipalities included in its composition, and the coordination of their actions, coordination of the regulatory framework of municipalities, including those aimed at optimizing budget expenditures. …”
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4042
A triterpene-enriched natural extract from Eucalyptus tereticornis modulates the expression of genes involved in adipogenesis, lipolysis, and extracellular matrix remodeling in a p...
Published 2025-12-01“…(Myrtaceae), with ursolic acid, oleanolic acid, and ursolic acid lactone mixed with minor metabolites, provided a superior antiobesity effect than reconstituted triterpenoid mixtures in adipocyte cell lines and a pre-diabetic mouse model. Further identification of the molecular mechanisms of action of this mixture of triterpenes is required.Objective This study analyzes the effect of the natural extract and its components on early RNA expression profiles in human primary cultured adipocytes and a mouse cell line.Materials and methods RNA was sequenced using the DNBseq platform and the EnrichR software to perform gene enrichment analysis using the Gene Ontology database, Kyoto Encyclopedia of Genes and Genomes, and Reactome. …”
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4043
Disruption of Gut Microbiota and Associated Fecal Metabolites in Collagen-Induced Arthritis Mice During the Early Stage
Published 2025-02-01“…Further revealing the microbiota and related metabolic disorders in the preclinical stage of RA (pre-RA) is of great significance for exploration of disease mechanisms.Methods: DBA/1 mice were injected with type II collagen on days 0 and 21 to establish collagen-induced arthritis (CIA) mouse model. …”
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4044
Randomised controlled trial of the effects of kefir on behaviour, sleep and the microbiome in children with ADHD: a study protocol
Published 2023-12-01“…The aim of this study is to explore the effects of supplementation with kefir (a fermented dairy drink) on ADHD symptomatology, sleep, attention and the gut microbiome in children diagnosed with ADHD.Methods and analysis A 6-week randomised, double-blind, placebo-controlled trial in 70 children aged 8–13 years diagnosed with ADHD. …”
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4045
Contextual Factors, Health History, and Daily Living Activities for Ovarian Cancer Risks: A Case-Control Study in Indonesia
Published 2023-08-01“…Methods: This retrospective case-control study included 408 women with a 1:1 balanced composition: 204 women diagnosed with ovarian cancer and 204 without. …”
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4046
Vaginal Lactobacillus gasseri biosurfactant: a novel bio- and eco-compatible anti-Candida agent
Published 2025-12-01“…The environmental impact of BS was also investigated on a microcosm model (spring water) by culture-based and molecular (16S rRNA-targeted Illumina sequencing) methods, and no remarkable modifications in the taxonomy composition of the bacterial ecosystem were observed.To conclude, BS from L. gasseri BC12 appears as a promising, biocompatible and environmentally friendly approach to prevent and treat VVC/RVVC.…”
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4047
Mechanisms of osteopontin-stabilized amorphous calcium phosphate calcification in benign and pre-malignant breast disease
Published 2025-07-01“…This work aims to guide development of methods to inhibit ACP calcifications within low-risk lesions that prompt unnecessary biopsies.…”
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4048
Parabacteroides johnsonii inhibits the onset and progression of colorectal cancer by modulating the gut microbiota
Published 2025-07-01“…However, the association between P. johnsonii and CRC remains unknown. Methods P. johnsonii (10–42) and Lactococcus formosensis (22–2) were isolated from healthy human feces. 29 mice that demonstrated normal feeding and activity were randomly assigned to four groups: normal control (NC group), CRC model (IC group), P. johnsonii (PJ group), and L. formosensis (LO group). …”
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4049
Examining Organic and Elemental Carbon Presence in Beauty Salon Service Rooms
Published 2025-05-01“…The carbon matrix of these particles can carry toxic compounds, potentially adversely affecting the health of salon employees. Methods Filtres with PM2.5 were analyzed for OC and EC content with Model 4L Sunset Laboratory thermal-optical OC/EC analyser. …”
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4050
Diagnosis by SAM Linked to Machine Vision Systems in Olive Pitting Machines
Published 2025-07-01“…The results validate SAM as a feasible option for industrial segmentation, offering a simpler and more accessible solution compared to traditional ANN-based methods. Moreover, our statistical analysis reveals that improper calibration—manifested as size deviations from the nominal value—does not significantly increase boat error rates. …”
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4051
The association between ultra-processed foods intake and the odds of prostate cancer: a case–control study
Published 2025-04-01“…The current study aimed to investigate the association between UPFs consumption and the odds of prostate cancer (PC). Methods This case–control study recruited 62 PC cases and 63 hospital-based controls from two major referral hospitals of Shiraz, Iran, in 2015. …”
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4052
<i>Vibrio cholerae</i> Gut Colonization of Zebrafish Larvae Induces a Dampened Sensorimotor Response
Published 2025-01-01“…A growing number of studies suggest that the gut microbiome composition modulates animal behavior. Zebrafish are an established cholera model that can maintain a complex, mature gut microbiome during infection. …”
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4053
Fluorescence Spectroscopy and a Convolutional Neural Network for High-Accuracy Japanese Green Tea Origin Identification
Published 2025-04-01“…These similarities are presumed to reflect the comparable growing conditions and processing methods characteristic of the two regions. This study shows the potential of this system in food origin identification, suggesting applications in preventing origin fraud and quality control. …”
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4054
Effects of beinaglutide on visceral fat area and gut microbiota in obesity
Published 2025-06-01“…The Homeostatic Model Assessment of Insulin Resistance index was calculated. …”
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4055
Integrating electrical resistivity tomography and x-ray fluorescence for characterizing limestone in the Wapulaka Formation, Central Buton, Indonesia
Published 2025-07-01“…This study illustrates the efficacy of integrating geophysical and geochemical methods to delineate intricate carbonate systems, providing insights into subsurface heterogeneity, diagenetic processes, and resource availability.…”
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4056
Decline in and recovery of fertility rates after COVID-19-related state of emergency in Japan
Published 2024-10-01“…This study aimed to evaluate the impact of COVID-19 infection rates and regional sociodemographic factors on the recovery of fertility rates in Japan following the state of emergency.Methods This study examined prefectural fertility data from before the COVID-19 pandemic to forecast fertility rates up to 2022 using a seasonal autoregressive integrated moving average model. …”
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4057
Effects of Cultivation Modes on Soil Protistan Communities and Its Associations with Production Quality in Lemon Farmlands
Published 2025-07-01“…The structure equation model revealed a direct correlation between the quality of lemons and the cultivation methods employed, as well as the composition of soil protists. …”
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4058
Gait speed in older adults: exploring the impact of functional, physical and social factors
Published 2024-12-01“…To assess physical function, SPPB tests (chair stand test, balance tests, gait speed test), manual grip strength, muscle quality index, and power were conducted, in addition to measuring body composition and socioeconomic status. Results: The final regression model showed that gait speed was significantly partially explained (R2=0.35; p<0.01) by the socioeconomic environment, age, balance, and relative power. …”
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4059
Alterations in gut microbiota of hyperthyroidism rats and the therapeutic effects of Radix Scrophulariae: A study based on fecal metabolomics and 16S rRNA gene sequencing analysis
Published 2025-03-01“…Methods: Hyperthyroid rats were treated with Radix Scrophulariae. …”
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4060
Patterns of conjunctival and scleral regeneration after intraoperative application of cyclosporin A solution in rabbits with steroid-induced glaucoma
Published 2021-07-01“…In an in vivo experiment, to study the effect of local intraoperative application of 0.05% cyclosporin A solution on the conjunctival and scleral regeneration after surgery on the rabbit eyes with steroid-induced glaucoma.Materials and methods. At the first stage of the experiment, a model of steroid-induced glaucoma was reproduced for 29 male Californian rabbits by injecting 0.5 ml of a 0.4% solution of dexamethasone subconjunctivally in both eyes once a week for 3 months (12 subconjunctival injections for each rabbit). …”
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