Microbiome and pediatric leukemia, diabetes, and allergies: Systematic review and meta-analysis. by Rachel Gallant, Samiha Reza, Joseph L Wiemels, Mel Greaves

“…We have assessed whether lower microbiome diversity (Shannon Index) and shared genus/species profiles are associated with pediatric ALL, allergies, and T1DM.<h4>Methods and findings</h4>Literature search was performed using PubMed, Embase, Cochrane, and Web of Science databases. …”
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Single-cell sequencing reveals dysregulated cell type perturbations and critical mediator communication remodelling in colorectal cancer by Chengyuan Xu, Chengyuan Xu, Siqi Zhang, Zhouyu Zhang, Luoqiu Zhang, Bin Sun, Zicheng Yu, Hailong Liu

“…Understanding the cellular composition and dynamic changes is essential for uncovering mechanisms of tumour progression.MethodsTo investigate the cellular heterogeneity and immune microenvironment of CRC, identifying critical subpopulations, functional pathways, and prognostic biomarkers, single-cell transcriptomic data from 41 CRC samples across four datasets were integrated. …”
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Parametric optimization of aloe vera coagulant for nitrate removal from textile wastewater using response surface methodology (RSM) by Lukman Shehu Mustapha, Kehinde Shola Obayomi

“…This objective was to use response surface methods to optimize operating parameters on the removal efficiency of nitrate removal through the application of response surface methodology (RSM). …”
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Bioinspired piezoelectric patch design for sonodynamic therapy: a preclinical mechanistic evaluation of rotator cuff repair and functional regeneration by Rui Shi, Rui Shi, Fei Liu, Qihuang Qin, Pinxue Li, Ziqi Huo, You Zhou, Chunyan Jiang

“…Piezoelectric materials, known for modulating cellular functions and promoting stem cell proliferation and differentiation, have garnered increasing attention in tissue repair applications.MethodsIn this study, a biomimetic piezoelectric patch with progressive compositional and structural variations was designed and fabricated. …”
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Identification of Ferroptosis‐Related Gene in Age‐Related Macular Degeneration Using Machine Learning by Meijiang Zhu, Jing Yu

“…This study aimed to investigate the involvement of ferroptosis in the progression of AMD. Methods A total of 41 samples of AMD and 50 normal samples were obtained from the data set GSE29801 for differential gene expression analysis and functional enrichment. …”
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Fine Depicting of Seepage Barrier for Gas Flooding in the Lower Wuerhe Formation Reservoir of the 8th District in China by Zhibin Jiang, Hongming Tang, Rui Shen, Xiaoguang Wang, Wei Zhou, Liming Lian, Lisha Qi, Dan Xie, Chuanchuan Qian, Jie Wang, Xiao Liu, Qiyao Liu

“…The effects of different types of interlayer combinations on gas injection were studied by combining the physical model and numerical simulation methods. The results showed that the lithology of the interlayer in the lower Wuerhe formation of the 8th district was mainly mud-bearing fine gravel with microporosity, average porosity of 6.1% and permeability of 0.0043 mD. …”
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AUTOIMMUNE OOPHORITIS AND THEIR CORRECTION BY GLUCOCORTICOIDS by T. V. Tupitsyna, S. V. Logvinov, O. A. Tikhonovskaya, M. L. Dmitrieva

“…Taking of the material was carried out by the 20th and the 60th day.Methods. The study of the ultrastructure ovaries were performed using transmission electron microscopy. …”
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Pathways for Potential Exposure to Onshore Oil and Gas Wastewater: What We Need to Know to Protect Human Health by Ayusha Ariana, Isabelle Cozzarelli, Cloelle Danforth, Bonnie McDevitt, Anna Rosofsky, Donna Vorhees

“…Knowledge gaps include understanding the variable composition and toxicity of produced water released to the environment, the performance of treatment methods, migration pathways through the environment that can result in human exposure, and the significance of the exposures for human and ecosystem health. …”
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Exploring the regenerative capacity of the spleen following irradiation by Christie T. M. Short, Helen C. O’Neill, Jonathan K. H. Tan

“…This highlights the importance of the haematopoietic niche and its recovery from myeloablation as an important therapeutic target.MethodsThis murine model study specifically considers changes in spleen tissue architecture and cellular composition involving stromal and vascular cells that occur following lethal irradiation.ResultsSpleen recovered fully between 4- and 8-weeks after irradiation due to reconstitution by HSPC from bone marrow. …”
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Evaluating Immune Activation Feasibility in Pancreatic Ductal Adenocarcinoma via Oxygen Bubble-Induced Anti-Vascular Therapy by Tzu-Yun Chiu, Yi-Jia Zho, Yi-Ju Ho

“…The feasibility of enhancing anti-tumor immune activation by alleviating tumor hypoxia was evaluated. <b>Methods:</b> A murine pancreatic subcutaneous solid tumor model was used to evaluate the efficacy of anti-vascular therapy-associated immunotherapy. …”
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Aqueous extracts of Elsholtzia ciliata and Hovenia dulcis ameliorate loperamide-induced constipation in mice by promoting intestinal peristalsis and barrier function and the abunda... by Junnan Wu, Junnan Wu, Qilei Xin, Shuo Wang, Xu Zhang, Chunping Jiang, Chunping Jiang

“…ObjectiveThe aims of the present study were to determine the efficacy of edible traditional Chinese medicines (ETCMs) in treating constipation, verify their laxative effects, and conduct preliminary investigations into their mechanisms of action.MethodsICR mice were treated with loperamide to induce constipation, and various fecal parameters, including fecal volume, water content, and intestinal transport function, were measured in these constipation model mice to screen for ETCMs with laxative properties. …”
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First experience in implantation of a mechanical circulatory support device based on a disk-type pump: an acute experiment by M. O. Zhulkov, A. M. Golovin, E. O. Golovina, A. S. Grenaderov, A. V. Fomichev, S. A. Alsov, A. M. Chernyavsky

“…Objective: to carry out the implantation of an artificial left ventricle of the heart based on a disk-type pump in an acute experiment on a large mammal (mini-pig). Materials and methods. To test the surgical technique of implantation and assess the biocompatibility of the apparatus for mechanical support of blood circulation based on a viscous friction pump, an acute experiment was conducted on an animal. …”
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Comparison of encrustation between silicon-covered and polytetrafluoroethylene-covered metallic stent, in vitro experimental study by Deok Hyun Han, Woo Jin Bang, Jae Hoon Chung

“…Materials and Methods: A total of 52 MUS were prepared: 26 silicon-covered and 26 PTFE-covered stents. …”
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Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients. by Michael J Cox, Elena M Turek, Catherine Hennessy, Ghazala K Mirza, Phillip L James, Meg Coleman, Andrew Jones, Robert Wilson, Diana Bilton, William O C Cookson, Miriam F Moffatt, Michael R Loebinger

“…However, the evidence base for antibiotic therapy is limited. DNA based methods offer better identification and quantification of microbial constituents of sputum than standard clinical culture and may help inform patient management strategies. …”
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Cholesterol-induced colorectal cancer progression and its mitigation through gut microbiota remodeling and simvastatin treatment by Xiaoliang Xie, Wenjing Wang, Haiming Zhang, Shaohui Zhao, Na Zhang, Ying Gao, Quanxia Liu, Xiaomei Chen

“…This study explores the impact of cholesterol on tumor growth and the potential therapeutic effects of Lactobacillus and Simvastatin. Methods We utilized a cecal tumor xenograft mouse model with Ldlr−/− mice to assess the effects of high cholesterol levels on tumor growth. …”
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Unraveling salivary microbiota diversity following kidney transplantation: insights from baseline peripheral blood lymphocyte subsets by Xuyu Xiang, Tianyin Wang, Peng Ding, Yi Zhu, Ke Cheng, Yingzi Ming

“…It is therefore hypothesized that the salivary microbiota may be linked to immune function.Materials and Methods We analyzed 108 saliva samples from 37 KT patients using 16S rRNA sequencing. …”
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Association between oral microbial diversity (only bacteria) and diabetes in U.S. adults: analysis of NHANES 2009–2012 data by Shu Yang, Shuo Zhang, Qian Cao, Guowei Zhu, Jikai Liu, Guoqing Li, Minmin Zhu

“…This study analyzed the oral microbial composition and diversity using NHANES data to explore its potential role in diabetes pathogenesis; Methods: A cross-sectional design was employed, utilizing NHANES data (2009–2012), including oral microbiota samples and diabetes-related indicators. …”
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Discovering biomarkers associated with infiltration of CD8+ T cells and tumor-associated fibrosis in colon adenocarcinoma using single-cell RNA sequencing and gene co-expression ne... by Jinning Zhang, Jinning Zhang, Ziquan Sun, Ziquan Sun, Guodong Li, Guodong Li, Lixian Ding, Zitong Wang, Ming Liu, Ming Liu

“…We utilized univariate Cox regression and LASSO analysis to create a prognostic model. The predictive model was assessed through Kaplan-Meier analysis, and a survival prediction nomogram was created. …”
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Control of butters in lines culinaris medic by V. Reznik, S. Moshkovska

“…To develop an effective system for the protection of crops of lentils from weeds by chemical methods. Objective: to investigate the dynamics of the processes of weed infestation, the species composition of weeds, the structure, number and mass of weeds; to study the factors of the negative impact of weeds on lentil plants in the process of their joint vegetation; search and evaluation in field conditions of the effectiveness of herbicides and their compositions on edible lentil crops. …”
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Comparative study of specific activity of rectal suppositories with clopidogrel by I. L. Kechyn, V. V. Hladyshev, O. L. Drozdov, O. B. Kharaponova, S. A. Hladysheva

“…The aim of the work is to investigate the specific activity of rectal suppositories with clopidogrel. Materials and methods. Experimental suppositories with clopidogrel 0,075 g for rectal administration were used as the objects in pre-line studies. …”
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