Exploring the potential of deep learning models integrating transformer and LSTM in predicting blood glucose levels for T1D patients by Xin Xiong, XinLiang Yang, Yunying Cai, Yuxin Xue, JianFeng He, Heng Su

“…Methods In this study, we propose a hybrid deep learning model combining Transformer and LSTM networks to predict blood glucose levels for up to 120 min. …”
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Ageing, multimorbidity, and quality of life: a mediation analysis using longitudinal ageing study in India by Bharti Singh, Ajay Kumar

“…The QoL score was constructed using Principal Component Analysis (PCA) by utilizing 21 factors under six domains (physical health, psychological health, social relationship, environmental satisfaction, life satisfaction and general health), with the composite QoL score ranging from 0 to 100. Further, the Structural equation model (SEM) was used to assess the role of multimorbidity as the intermediating risk factor for exogenous factors on QoL.ResultsDistributions of morbidities burden were skewed toward non-communicable diseases (NCDs) and sequentially escalated multimorbidity burden was observed among the oldest of old age groups. …”
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Advancing ship automatic navigation strategy with prior knowledge and hierarchical penalty in irregular obstacles: a reinforcement learning approach to enhanced efficiency and safe... by Hao Zhang, Jiawen Li, Jiawen Li, Jiawen Li, Jiawen Li, Liang Cao, Liang Cao, Liang Cao, Shucan Wang, Ronghui Li, Ronghui Li, Ronghui Li

“…The experimental results show that the GEPA model outperforms the existing methods in terms of navigating efficiency, training convergence speed, path smoothness, obstacle avoidance ability and safety, with the number of training rounds to complete the task reduced by 24.85%, the path length reduced by up to about 70 pixels, the safety distance improved by 70.6%, and the number of collisions decreased significantly. …”
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National-scale mapping topsoil organic carbon of cropland in China using multitemporal Sentinel-2 images by Jie Xue, Xianglin Zhang, Songchao Chen, Zhongxing Chen, Rui Lu, Feng Liu, Bas van Wesemael, Zhou Shi

“…First, a new time-series bare soil extraction method, the Two-Dimensional Bare Soil Separation Algorithm, was applied, utilizing Sentinel-2 images from 2018 to 2022 to generate a continuous spectral reflectance composite. …”
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Outcomes After Noncardiac Surgery Performed Within 2 Years of Percutaneous Coronary Intervention by Neel M. Butala, Annika Hebbe, Binita Shah, Nathaniel R. Smilowitz, Bilal Aijaz, Anezi Uzendu, Peter Boulos, Stephen W. Waldo

“…Methods and Results Patients in the Veterans Affairs Surgical Quality Improvement Program database who underwent noncardiac surgery between October 1, 2017 and September 30, 2021 were included. …”
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Construction of a predictive model for concurrent infection in liver failure patients based on prognostic nutritional index and inflammatory cytokine analysis by Hong Yang, Bin Zhang, Chun Yu, Xiao Zhu

“…Abstract Objective This study aimed to explore the relationship between the Prognostic Nutritional Index (PNI, a composite indicator of albumin and lymphocyte count reflecting nutritional and immune status) and inflammatory cytokines in predicting infections among liver failure patients, and to construct a predictive model based on these indicators. …”
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Identification of Plasma Metabolites Responding to Oxycodone Exposure in Rats by Thao Vu, Suneeta Godbole, Lieselot L. G. Carrette, Lisa Maturin, Olivier George, Laura M. Saba, Katerina Kechris

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Numerical and Artificial Neural Network Analysis of Magnetohydrodynamic Natural Convection in a Nano-encapsulated Phase Change Suspension Filled Quadrantal Circular Enclosure by Mehdi Ghalambaz, Ioan Pop, Mikhail Sheremet, Mohammed Ali, Mohammad Ghalambaz

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Supporting the Design of Systems for Energy Recovery from Mechanical Vibrations Containing MFC Piezoelectric Transducers by Marek Płaczek, Łukasz Dulat

“…The aim of this research work was to develop and experimentally validate tools to support the design and manufacture of systems that recover electrical energy from mechanical vibrations using non-classical composite piezoelectric transducers. For this purpose, a mathematical model of this type of system was developed, which was then combined with computer-aided engineering tools and the application of the finite element method. …”
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TiO₂/SWCNts: Linear and Nonlinear Optical Studies for Environmental Applications by Saloua Helali

“…The X-ray diffraction method was used to investigate the structure of the samples. …”
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Single-cell transcriptomics reveal the prognostic roles of epithelial and T cells and DNA methylation-based prognostic models in pancreatic cancer by Jing Du, Yaqian Zhao, Jie Dong, Peng Li, Yan Hu, Hailang Fan, Feifan Zhang, Lanlan Sun, Dake Zhang, Yuhua Zhang

“…The TCGA dataset was used for validation, and cell composition was inferred from DNAm data. Prognostic models were constructed based on cell-type-specific DNAm markers, and genomic features were compared across risk groups. …”
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In vivo percutaneous microwave ablation with ECO system in swine kidney and liver: comparison of ablation-zone size to manufacturer predictions and assessment of new antenna design by Théo Bonnefoy, Georges Tarris, Kévin Guillen, Olivia Poupardin, Olivier Chevallier, Ludwig Serge Aho Glele, Jean-Michel Correas, Romaric Loffroy

“…Power and application time are chosen based on manufacturer-provided data, usually obtained from ex vivo animal models. However, ex vivo tissues differ from in vivo condition due to compositional changes and absence of heat dissipation by blood flow. …”
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Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model by Cassandra M. Flynn, Tamunotonye Omoluabi, Alyssa M. Janes, Emma J. Rodgers, Sarah E. Torraville, Brenda L. Negandhi, Timothy E. Nobel, Shyamchand Mayengbam, Qi Yuan

“…Methods This study evaluates the effects of probiotics in a rat model of preclinical AD, specifically targeting hyperphosphorylated pretangle tau in the locus coeruleus. …”
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Using 3D and 4D digital human modeling in extended reality-based rehabilitation: a systematic review by Mengdi Lu, Wim Saeys, Wim Saeys, Maria Maryam, Inva Gjeleshi, Hoda Nazarahari, Steven Truijen, Sofia Scataglini

“…Recently, integrating digital human modeling (DHM) with XR has gained attention. This systematic review aimed to evaluate the effectiveness of combining 3D and 4D DHM with XR in rehabilitation.MethodsA systematic literature search was conducted according to PRISMA 2020 guidelines on the 28th of May 2024 in five databases (PubMed, IEEE Database, Cochrane Library, Web of Science, and Science Direct). …”
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Development of in vitro laboratory models of the tumor immune microenvironment to evaluate quality parameters and specific efficacy of the dendritic cell vaccine by T. L. Nekhaeva, A. B. Danilova, E. I. Fedoros, N. A. Efremova, N. V. Emelyanova, M. L. Blokhina, M. N. Yurova, M. L. Tyndyk, I. A. Baldueva

“…Purpose of the study: development of in vitro laboratory models to evaluate quality parameters and specific efficacy of dendritic cell vaccine (DCV).Material and Methods. …”
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Semi-analytical dynamic modeling and impact mechanism analysis of a hard-coating cylindrical shell with arbitrary circular perforations by Jian Yang, Yue Zhang

“…Abstract In this paper, an innovative axial domain decomposition method, which uniquely integrates axial and circumferential perforation parameters, is developed for semi-analytical modeling of free vibration of a hard-coating cylindrical shell with arbitrary axial and circumferential perforations, based on the Love’s first-order shear deformation theory and Rayleigh-Ritz method. …”
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Muscle‐specific gene editing improves molecular and phenotypic defects in a mouse model of myotonic dystrophy type 1 by Mariapaola Izzo, Jonathan Battistini, Elisabetta Golini, Christine Voellenkle, Claudia Provenzano, Tiziana Orsini, Georgios Strimpakos, Ferdinando Scavizzi, Marcello Raspa, Denisa Baci, Svetlana Frolova, Spyros Tastsoglou, Germana Zaccagnini, Jose Manuel Garcia‐Manteiga, Genevieve Gourdon, Silvia Mandillo, Beatrice Cardinali, Fabio Martelli, Germana Falcone

“…The precision and efficiency of the molecular mechanisms are still under investigation in view of a possible use in clinical practice. Methods Here, we describe the application of the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated protein 9 (Cas9) strategy to remove the CTG‐expansion in the DMPK gene in a mouse model carrying the human transgene from a DM1 patient. …”
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Enhanced efficacy of immune checkpoint inhibitors by folate-targeted multifunctional drug through synergistic therapy inducing ferroptosis and immunogenic cell death in bladder can... by Yibo Shi, Guangrui Fan, Enguang Yang, Yuanfeng Zhang, Hui Ding, Junqiang Tian, Liang Cheng, Hanzhang Wang, Tianzhi Hao, Baodui Wang, Zhiping Wang

“…Methods: DIFP-FA was synthesized via the W/O/W method. …”
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Synthesis of novel magnesium ferrite Schiff base chitosan nanocomposite for efficient removal of pb(II) ions from aqueous media by Nada S. Al-Kadhi, Ehab A. Abdelrahman, Fowzia S. Alamro, Reem K. Shah, Fawaz A. Saad, Khalil ur Rehman

“…Abstract In this study, a novel MgFe2O4-Schiff base-chitosan nanocomposite was synthesized using a straightforward crosslinking method. The synthesis involved integrating MgFe2O4 nanoparticles with modified chitosan through a Schiff base formed by the reaction between terephthalaldehyde and aminopyrazine. …”
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Interplay between the gut microbiome and typhoid fever: insights from endemic countries and a controlled human infection model by Philip M. Ashton, Leonardos Mageiros, James E. Meiring, Angeziwa Chunga-Chirambo, Farhana Khanam, Sabina Dongol, Happy Banda, Abhilasha Karkey, Lorena Preciado-Llanes, Helena Thomaides-Brears, Malick Gibani, Nazmul Hasan Rajib, Nazia Rahman, Prasanta Kumar Biswas, Md Amirul Islam Bhuiyan, Sally Kay, Kate Auger, Olivier Seret, Nicholas R. Thomson, Andrew J. Pollard, Stephen Baker, Buddha Basnyat, John D. Clemens, Christiane Dolecek, Sarah J. Dunstan, Gordon Dougan, Robert S. Heyderman, Virginia E. Pitzer, Firdausi Qadri, Melita A. Gordon, Kathryn E. Holt, Thomas C. Darton, STRATAA Study Group

“…There is some evidence that bacteria producing short-chain fatty acids (SCFAs) may create an environment unfavourable to invasive Salmonella, but data from humans is limited. Methods To investigate the association between the gut microbiome and typhoid fever, we analysed samples collected from three all-age cohorts enrolled in a prospective surveillance study conducted across three settings where typhoid fever is endemic (Dhaka, Bangladesh; Blantyre, Malawi; and Kathmandu, Nepal). …”
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