Self‐Report Tool for Identification of Individuals With Coronary Atherosclerosis: The Swedish CardioPulmonary BioImage Study by Göran Bergström, Eva Hagberg, Elias Björnson, Martin Adiels, Carl Bonander, Ulf Strömberg, Jonas Andersson, Mattias Brunström, Carl‐Johan Carlhäll, Gunnar Engström, David Erlinge, Isabel Goncalves, Anders Gummesson, Emil Hagström, Ola Hjelmgren, Stefan James, Magnus Janzon, Lena Jonasson, Lars Lind, Martin Magnusson, Viktor Oskarsson, Johan Sundström, Per Svensson, Stefan Söderberg, Raquel Themudo, Carl Johan Östgren, Tomas Jernberg

“…For comparison, we also developed a tool using variables from laboratory tests, physical examinations, and self‐report (clinical tool) and evaluated both models using receiver operating characteristic curve analysis, external validation, and benchmarked against factors in the pooled cohort equation. …”
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HiSNAP trial—a multicentre, randomised, open-label, blinded end point, safety and efficacy trial of conventional (300 mg/kg) versus higher doses of acetylcysteine (450 mg/kg and 60... by Alasdair Gray, David M Wood, Jacqueline James, Keith Boath, Rajendra Raman, Matt Reed, Rachel O’Brien, Alison Grant, Sharon Tuck, Liza Keating, Craig Davidson, Christopher J Weir, Jonathan Carter, Stephen Lynch, James W Dear, Michael Eddleston, Lyle Moncur, Julia Grahamslaw, Katherine Oatey, Marianne Gillings, Lynsey Milne, Natalie Homer, Caroline Blackstock, Philippa Wright, Christopher Humphries, Alan Timmins, Laura Muir, Ruben Thanacoody, Ellise Clarke, Heather Robertson, Anna Miell, Chloe Haigh, Luisa Padovani, Karen Gray, Sandra Pirie, Christina Coventry, Amy Armstrong, Sian Irvine, Oliver Carlill, Donna Clark, Fraser Craig, Angela Crawford, Carlyn Davie, Judith Flemming, Marie-Claire Harris, Katy Letham, Malgorzata Litwin, Fiona McCurrach, Shona McDonald, Fraser McFadyen, Hazel Milligan, Victoria Minnis, Gillian Pickering, Rebecca Rielly, Emma-Beth Wilson, Lisa-Marie Butt, Kathleen Scullion, Claire Cheyne, Angela McGeough, Nikki McLaughlin, Fern Purdie, Sandee Beattie, Anna Borkowska, Katie Hamilton, Keith Jacques, Jeronimo Martin Ramirez, Vasilika Ntoko, Surinder Pandhor, Janine Ramsey, Maria Simpson

“…Basic pharmacology, mathematical modelling and observational studies suggest that this dose may be insufficient in some patients (particularly those taking a large overdose).Methods and analysis A multicentre trial, taking place across several hospitals in Scotland, UK, within Emergency Departments and Acute Medical Units. …”
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Seismic and Post-Seismic Ductility and Forces of Mid-Story Pin Moment-Resisting Frames Based on Scale of Local Deformation of I-Beam’s Segments by Atsushi Suzuki, Ruiyu Che, Yoshihiro Kimura

“…This paper utilizes shell finite element analysis (FEA) models to examine the demanded column-to-beam strength ratio to keep the column elastic and maximize the story drift at the moment of beam buckling of the frame. …”
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Looking at the Distant Universe with the MeerKAT Array: The H i Mass Function in the Local Universe by Amir Kazemi-Moridani, Andrew J. Baker, Marc Verheijen, Eric Gawiser, Sarah-Louise Blyth, Danail Obreschkow, Laurent Chemin, Jordan D. Collier, Kyle W. Cook, Jacinta Delhaize, Ed Elson, Bradley S. Frank, Marcin Glowacki, Kelley M. Hess, Benne W. Holwerda, Zackary L. Hutchens, Matt J. Jarvis, Melanie Kaasinen, Sphesihle Makhathini, Abhisek Mohapatra, Hengxing Pan, Anja C. Schröder, Leyya Stockenstroom, Mattia Vaccari, Tobias Westmeier, John F. Wu, Martin Zwaan

“…Our analysis, which implements a forward modeling approach, corrects for survey incompleteness and uses extensive synthetic source injections to ensure robust estimates of the H i MF parameters and their associated uncertainties. …”
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Regional adipose distribution and metabolically unhealthy phenotype in Chinese adults: evidence from China National Health Survey by Binbin Lin, Yaoda Hu, Huijing He, Xingming Chen, Qiong Ou, Yawen Liu, Tan Xu, Ji Tu, Ang Li, Qihang Liu, Tianshu Xi, Zhiming Lu, Weihao Wang, Haibo Huang, Da Xu, Zhili Chen, Zichao Wang, Guangliang Shan

“…Odds ratios (ORs) and their 95% confidence intervals (CIs) were estimated by logistic regression models. All analyses were performed separately by sex. …”
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Micronutrient dose response (MiNDR) study among women of reproductive age and pregnant women in rural Bangladesh: study protocol for double-blind, randomised, controlled trials by Tahmeed Ahmed, Hasmot Ali, Michael Rosenblum, Daniel J Erchick, Towfida Jahan Siddiqua, Rezwanul Haque, Parul Christian, Sarah Baker, Eleonor Zavala, Kerry J Schulze, SM Tafsir Hasan, Khalid Bin Ahsan, Sulagna Bandyopadhyay, Hasan Mahmud Sujan, Md. Hafizur Rahman, Katherine K Stephenson, Ximing Ge, Ethan K Gough, Brooke Langevin, Lee Shu Fune Wu, Brian Dyer, Anjan Kumar Roy, Mohammad Jubair, Amena Al Nishan, Mathangi Gopalakrishnan, Klaus Kraemer

“…A bioefficacy study to determine amounts required to attain nutrient adequacy among women of reproductive age (WRA) and pregnant women (PW) aims to address this gap.Methods and analysis Two, four-arm, dose-response trials (n=240 participants/trial) with a double-blind, individually randomised, controlled design are underway in 18–35 year-old WRA and PW in rural northern Bangladesh. …”
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Vitamin K‐dependent gamma‐carboxyglutamic acid protein 1 promotes pancreatic ductal adenocarcinoma progression through stabilizing oncoprotein KRAS and tyrosine kinase receptor EGF... by Zheng Wu, Qing Ye, Shan Zhang, Li‐Peng Hu, Xiao‐Qi Wang, Lin‐Li Yao, Lei Zhu, Shu‐Yu Xiao, Zong‐Hao Duan, Xue‐Li Zhang, Shu‐Heng Jiang, Zhi‐Gang Zhang, De‐Jun Liu, Dong‐Xue Li, Xiao‐Mei Yang

“…The molecular function of transmembrane proline‐rich Gla proteins (PRRGs) remains unexplored. Methods Analysis of pancreatic ductal adenocarcinoma (PDAC) datasets, including transcription profiles, clinical data, and tissue microarrays, was conducted to evaluate PRRG1 expression and its clinical relevance. …”
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Improved Robust Stability Criterion of Networked Control Systems with Transmission Delays and Packet Loss by Shenping Xiao, Liyan Wang, Hongbing Zeng, Wubin Cheng

“…Based on the working mechanism of zero-order holder, the closed-loop NCS is modeled as a continuous-time linear system with input delay. …”
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Direct sequencing of small genomes on the Pacific Biosciences RS without library preparation by Paul Coupland, Tamir Chandra, Mike Quail, Wolf Reik, Harold Swerdlow

“…To date this approach has been applied toward sequencing single-stranded and double-stranded viral genomes, bacterial plasmids, plasmid vector models for DNA-modification analysis, and linear DNA fragments covering an entire bacterial genome. …”
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Effective diffusivity in yacon potato cylinders during drying by Cícera G. C. de Lisboa, Josivanda P. Gomes, Rossana M. F. de Figueirêdo, Alexandre J. de M. Queiroz, Adelino de M. G. Diógenes, João C. S. de Melo

“…Non-linear regression analysis was performed by the Quasi-Newton method using the program Statistica 7.0, where the parameters of the models were estimated as a function of the drying air temperature. …”
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Mitigation of chemotherapy-induced gut dysbiosis and diarrhea by supplementation with heat-killed Bacteroides fragilis by Xinwen Yan, Xinlong Lin, Jianhua Wu, Lijun Zheng, Yangyang Liu, Fang Wu, Ying Lin, Yishi Lu, Chongyang Huang, Binhai Shen, Hongbin Liu, Ruo Huang, Fengyi Hou, Qian Zhou, Mengyao Song, Ke Liu, Fangqing Zhu, Sheng Li, Yuqing Lin, Wei Wang, Ping Li, Wangjun Liao, Fachao Zhi

“…Mechanistic studies were conducted in murine models, complemented by IEC-6 cells and intestinal organoid experiments to elucidate microbiota-host interactions. …”
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Quantitative RT-PCR Amplification of RNA in Single Mouse Oocytes and Preimplantation Embryos by Maria Teresa Fiorenza, Franco Mangia

“…We describe a simple whole-cell method for quantitative reverse transcription (RT) PCR amplification of RNA that consistently allows the analysis of trace amounts of RNA, such as those carried by a fraction of a single mouse oocyte or preimplantation embryo, without organic extraction. …”
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Efficacy, cost-utility and physiological effects of Acceptance and Commitment Therapy (ACT) and Behavioural Activation Treatment for Depression (BATD) in patients with chronic low... by Antonio I Cuesta-Vargas, Azucena García-Palacios, Juan P Sanabria-Mazo, Carlos G Forero, Paula Cristobal-Narváez, Ariadna Colomer-Carbonell, Adrián Pérez-Aranda, Laura Andrés-Rodríguez, Lance M McCracken, Francesco D'Amico, Pere Estivill-Rodríguez, Bernat Carreras-Marcos, Antonio Montes-Pérez, Olga Comps-Vicente, Montserrat Esteve, Mar Grasa, Araceli Rosa, Michael Maes, Xavier Borràs, Silvia Edo, Antoni Sanz, Albert Feliu-Soler, Juan R Castaño-Asins, Juan V Luciano

“…The objectives of this 12 month, multicentre, randomised, controlled trial (RCT) are (i) to examine the efficacy and cost-utility of adding a group-based form of ACT or BATD to treatment-as-usual (TAU) for patients with CLBP and moderate to severe levels of depressive symptoms; (ii) identify pre–post differences in levels of some physiological variables and (iii) analyse the role of polymorphisms in the FKBP5 gene, psychological process measures and physiological variables as mediators or moderators of long-term clinical changes.Methods and analysis Participants will be 225 patients with CLBP and moderate to severe depression symptoms recruited at Parc Sanitari Sant Joan de Déu (St. …”
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Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: protocol for the TREADON randomised multi-arm multi-stage adapt... by Thomas Jaki, Melaine A Holden, Anne-Maree Keenan, Royes Joseph, Christian D Mallen, Hylton B Menz, Jesse Kigozi, Edward Roddy, Pavel Mozgunov, Martin J Thomas, Kendra Cooke, Jo Smith, Gemma Hughes, Emma Marshall, Martyn Lewis, Stephanie Butler-Walley, Simon Wathall, Laura Bowyer, June Brammar, Sarah A Lawton, Chris Drake, Thomas Burnett, Gordon J Hendry, Nadine E Foster

“…Objectives To determine the clinical and cost-effectiveness of individualised exercises and/or prefabricated foot orthoses plus self-management advice (SMA) compared to SMA alone in adults with PHP. Methods A multi-centre four-arm two-stage adaptive parallel-group RCT with internal pilot. …”
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The Association of Heart Failure and Liver T1 Mapping in Cardiac Magnetic Resonance Imaging by Adrian T. Huber, Joanna Bartkowiak, Robin Seitz, Benedikt Bernhard, Martina Boscolo Berto, Giancarlo Spano, Benedikt Wagner, Verena C. Obmann, Lukas Ebner, Inga A. S. Todorski, Michael P. Brönnimann, Kady Fischer, Dominik P. Guensch, Andreas Christe, Annalisa Berzigotti, Lorenz Räber, Tobias Reichlin, Thomas Pilgrim, Fabien Praz, Christoph Gräni, Nicholas Brugger, Alan A. Peters

“…Comparisons of the liver T1 values and echocardiographic parameters between patients with and without elevated NT-proBNP levels (>125 pg/mL) were conducted using the Mann–Whitney U test. Logistic regression models were employed to adjust for confounding factors. …”
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Targeting of the G9a, DNMT1 and UHRF1 epigenetic complex as an effective strategy against pancreatic ductal adenocarcinoma by Daniel Oyon, Amaya Lopez-Pascual, Borja Castello-Uribe, Iker Uriarte, Giulia Orsi, Sofia Llorente, Jasmin Elurbide, Elena Adan-Villaescusa, Emiliana Valbuena-Goiricelaya, Ainara Irigaray-Miramon, Maria Ujue Latasa, Luz A. Martinez-Perez, Luca Reggiani Bonetti, Felipe Prosper, Mariano Ponz-Sarvise, Silvestre Vicent, Antonio Pineda-Lucena, David Ruiz-Clavijo, Bruno Sangro, Urko Aguirre Larracoechea, Tian V. Tian, Andrea Casadei-Gardini, Irene Amat, Maria Arechederra, Carmen Berasain, Jesus M. Urman, Matias A. Avila, Maite G. Fernandez-Barrena

“…We also evaluated the therapeutic potential of an innovative inhibitor targeting these epigenetic effectors. Methods Immunohistochemical analysis of DNMT1, G9a, and UHRF1 expression was conducted in human PDAC tissue samples. …”
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Environmental phenol mixture during pregnancy and child sleep quality in the ECHO cohort by Sarah D. Geiger, Sarah D. Geiger, Xiaoshuang Xun, Cai Zhang, Cai Zhang, Aruna Chandran, Kritika Madan, Grace Kim, Fatima Naveed, Megan Woodbury, Dana E. Goin, Stephanie M. Eick, Courtney K. Blackwell, Maxwell Mansolf, Max Aung, Akram Alshawabkeh, Dana Dabelea, Anne L. Dunlop, Assiamira Ferrara, Jonika B. Hash, Monique Hedderson, Erica Jansen, Monique LeBourgeois, Louise O’Brien, Yeyi Zhu, Susan L. Schantz, Susan L. Schantz

“…The present analysis was conducted in 2023–2024. Using single-pollutant and mixture models, we examined associations between prenatal phenol concentrations and three key child sleep quality outcomes: sleep problems, disturbance, and impairment. …”
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Kinerja Karyawan Dipengaruhi Mediasi Kepuasan kerja Melalui Beban Kerja dan Servant Leadership by Adam Damiri, Wawan Prahiawan, Ali Imron Imron

“…Structural Equation Modelling SmartPLS 4.0 analysis, this tool is analyize method used in this research. based on findings of the hypothesis, it was investigated in this study. …”
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Pengaruh Penerapan Akuntabilitas Keuangan, Pemanfaatan Teknologi Informasi, Kompetensi Aparatur Pemerintah Dan Ketaatan Peraturan Perundangan Terhadap Kinerja Instansi Pemerintah (... by Dariana Dariana, Annisa Meidyaroza Harrie

“…This research uses multiple linear regression analysis models. The results of this research indicate that partially and simultaneously financial accountability, utilization of information technology, the competence of local government officials and obedience of laws and regulations have a significant effect on the performance of government agencies (good governance) in Bengkalis Regency regional apparatus organizations.…”
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(Re)concevoir les temps, le travail et les temps de travail à partir de la simulation : proposition théorique et méthodologique by Marlène Cheyrouze, Béatrice Barthe

“…These simulation tools are of three types: temporal models, spatial models and mental diagrams. They were deployed in groups of people affected by the changes: carers, managers, doctors and secretaries. …”
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