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  1. 69761

    Global Carbon Budget 2024 by P. Friedlingstein, P. Friedlingstein, M. O'Sullivan, M. W. Jones, R. M. Andrew, J. Hauck, J. Hauck, P. Landschützer, C. Le Quéré, H. Li, H. Li, I. T. Luijkx, A. Olsen, A. Olsen, G. P. Peters, W. Peters, W. Peters, J. Pongratz, J. Pongratz, C. Schwingshackl, S. Sitch, J. G. Canadell, P. Ciais, R. B. Jackson, R. B. Jackson, S. R. Alin, A. Arneth, V. Arora, N. R. Bates, M. Becker, M. Becker, N. Bellouin, C. F. Berghoff, H. C. Bittig, L. Bopp, P. Cadule, K. Campbell, M. A. Chamberlain, N. Chandra, F. Chevallier, L. P. Chini, T. Colligan, J. Decayeux, L. M. Djeutchouang, L. M. Djeutchouang, X. Dou, C. Duran Rojas, K. Enyo, W. Evans, A. R. Fay, R. A. Feely, D. J. Ford, A. Foster, T. Gasser, M. Gehlen, T. Gkritzalis, G. Grassi, L. Gregor, N. Gruber, Ö. Gürses, I. Harris, M. Hefner, M. Hefner, J. Heinke, G. C. Hurtt, Y. Iida, T. Ilyina, T. Ilyina, T. Ilyina, A. R. Jacobson, A. R. Jacobson, A. K. Jain, T. Jarníková, A. Jersild, F. Jiang, Z. Jin, Z. Jin, E. Kato, R. F. Keeling, K. Klein Goldewijk, J. Knauer, J. Knauer, J. I. Korsbakken, X. Lan, X. Lan, S. K. Lauvset, S. K. Lauvset, N. Lefèvre, Z. Liu, J. Liu, J. Liu, L. Ma, S. Maksyutov, G. Marland, G. Marland, N. Mayot, P. C. McGuire, N. Metzl, N. M. Monacci, E. J. Morgan, S.-I. Nakaoka, C. Neill, Y. Niwa, T. Nützel, L. Olivier, L. Olivier, T. Ono, P. I. Palmer, P. I. Palmer, D. Pierrot, Z. Qin, L. Resplandy, L. Resplandy, A. Roobaert, T. M. Rosan, C. Rödenbeck, J. Schwinger, J. Schwinger, T. L. Smallman, T. L. Smallman, S. M. Smith, R. Sospedra-Alfonso, T. Steinhoff, T. Steinhoff, Q. Sun, A. J. Sutton, R. Séférian, S. Takao, H. Tatebe, H. Tatebe, H. Tian, B. Tilbrook, B. Tilbrook, O. Torres, E. Tourigny, H. Tsujino, F. Tubiello, G. van der Werf, R. Wanninkhof, X. Wang, D. Yang, X. Yang, Z. Yu, W. Yuan, X. Yue, S. Zaehle, N. Zeng, N. Zeng, J. Zeng

    Published 2025-03-01
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  2. 69762
  3. 69763
  4. 69764
  5. 69765

    Targeting Stat3 with conditional knockout or PROTAC technology alleviates renal injury by Limiting pyroptosisResearch in context by Ming-lu Ji, Jia-nan Wang, Ming-fei Wu, Chuan-hui Xu, Meng-meng Zhang, Wen-bao Chang, Xin-fei Mao, Chao Li, Ju-tao Yu, Dan-feng Zhang, Xiao-guo Suo, Shao-xi Diao, Nan-nan Ma, Ying Chen, Rui Hou, Hao Lu, Shuai-shuai Xie, Yu-hang Dong, Qi Zhu, Xin Chen, Tao Xu, Wei Shao, Juan Jin, Jia-gen Wen, Xiao-wu Dong, Wen-bin Wang, Jin-xin Che, Xiao-ming Meng

    Published 2025-06-01
    “…The role of the Signal Transducer and Activator of Transcription 3 (Stat3) in AKI remains controversial, and its complex regulatory mechanisms must be further explored. Methods: We generated renal tubular epithelial cells Stat3 conditional knockout (cKO) mice and used them in cecal ligation and puncture (CLP) and ischaemia-reperfusion (I/R) induced AKI models. …”
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  6. 69766

    A Novel Definition and Grading Diagnostic Criteria for Tumour‐Type‐Specific Comprehensive Cachexia Risk by Chunlei Hu, Minghua Cong, Chunhua Song, Hongxia Xu, Zengqing Guo, Fuxiang Zhou, Lan Zhou, Min Weng, Benqiang Rao, Li Deng, Kaiying Yu, Yongbing Chen, Ziwen Wang, Guotian Ruan, Ming Yang, Chenan Liu, Jiuwei Cui, Wei Li, Kunhua Wang, Zengning Li, Ming Liu, Tao Li, Junqiang Chen, Stephan vonHaehling, Rocco Barazzoni, Hanping Shi

    Published 2025-04-01
    “…Risk factors for cachexia, including tumour characteristics and nutritional parameters, were examined to develop diagnostic scales using Cox proportional hazards models and Kaplan–Meier analysis. Results Ten nutrition items (body mass index, weight loss, intake reduction, physical activity function, fatigue, handgrip strength, anorexia, albumin level, albumin/globulin ratio and neutrophil/lymphocyte ratio) with different weighted scores were identified to construct a nutrition‐weighted scoring scale (NWSS) for nutrition risk. …”
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  7. 69767

    تقييم تأثير وسائل الاعلام والدعاية على إدراک المستخدمين للعمارة والعمران "دراسة حالة مشروعات الاسکان في مصر"... by محمود سليمان, ولاء زقدان

    Published 2019-03-01
    “….- Evaluating the role played by mass media, in terms of positivity and negativity, through running an analysis of the messages conveyed by media and advertising, whichare often influenced by the vision of the investing developers, in quest for marketing their housing products.- Detecting the criteria upon which the mass media rely in order to market an architectural product, to see if such mass media adopt honesty in presenting the characteristicsof the product, and to see whether such presentation provides the user with the informed knowledge of what he/she is going to possess or not.- Outline controls system to regulate the methods of promotion and marketing, in connection with the information to be provided by the mass media about the architecturalproducts available at the housing market, to enable residence seekers to select the most suitable product, among the available residential models, in accordance wi th theirdiverse and versatile characteristics and needs.…”
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  8. 69768
  9. 69769

    Racial/ethnic disparities in the association of maternal diabetes and obesity with risk of preterm birth among 17 million mother-infant pairs in the United States: a population-bas... by Juan Xie, Yuxiang Yan, Ziyi Ye, Yuxiao Wu, Yongfu Yu, Yangbo Sun, Shuang Rong, Donna A. Santillan, Kelli Ryckman, Linda G. Snetselaar, Buyun Liu, Wei Bao

    Published 2025-03-01
    “…We further categorized preterm birth into three subtypes: extremely (< 28 weeks), very (28–31 weeks), and moderately (32–36 weeks) preterm birth. Logistic regression models were used for association analyses in this study. …”
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  10. 69770
  11. 69771

    EPOCHS. XI. The Structure and Morphology of Galaxies in the Epoch of Reionization to z ∼ 12.5 by Lewi Westcott, Christopher J. Conselice, Thomas Harvey, Duncan Austin, Nathan Adams, Fabricio Ferrari, Leonardo Ferreira, James Trussler, Qiong Li, Vadim Rusakov, Qiao Duan, Honor Harris, Caio Goolsby, Thomas J. Broadhurst, Dan Coe, Seth H. Cohen, Simon P. Driver, Jordan C. J. D’Silva, Brenda Frye, Norman A. Grogin, Nimish P. Hathi, Rolf A. Jansen, Anton M. Koekemoer, Madeline A. Marshall, Rafael Ortiz III, Nor Pirzkal, Aaron Robotham, Russell E. Ryan Jr, Jake Summers, Christopher N. A. Willmer, Rogier A. Windhorst, Haojing Yan

    Published 2025-01-01
    “…We use standard software to fit single Sérsic models to each galaxy in the rest-frame optical and extract their parametric structural parameters (Sérsic index, half-light radius, and axis ratio) and Morfometryka to measure their nonparametric concentration and asymmetry parameters. …”
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  12. 69772
  13. 69773
  14. 69774

    Emotional literacy programme in special schools for children with a learning disability in England: the ZF-SEND feasibility RCT by Biza Stenfert Kroese, Gemma Unwin, Richard Hastings, Andrew Jahoda, Rachel McNamara, David Gillespie, Jeremy Segrott, Kate Ingarfield, Myrsini Gianatsi, Elizabeth Randell, Zoe Mather, Barbara Barrett, Poushali Ganguli, John Rose, Mariam Sahle, Emily Warren, Nathan Da Cruz

    Published 2024-12-01
    “…To inform a future trial, effect sizes and 95% CIs were estimated around the between-group comparisons of clinical measures (secondary outcomes) collected as part of the study. This analysis was based on the intention-to-treat principle and controlled for the clustered nature of children within schools using two-level mixed models. …”
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  15. 69775

    Worse recovery from acute attacks and faster disability accumulation highlights the unmet need for improved treatment in patients with late-onset neuromyelitis optica spectrum diso... by Julian Reza Kretschmer, Daria Tkachenko, Tania Kümpfel, Joachim Havla, Daniel Engels, Friedemann Paul, Friedemann Paul, Patrick Schindler, Patrick Schindler, Judith Bellmann-Strobl, Judith Bellmann-Strobl, Achim Berthele, Katrin Giglhuber, Clarissa Zappe, Luisa Klotz, Lisa Revie, Eva Dawin, Makbule Senel, Hayrettin Tumani, Florian Then Bergh, Clemens Warnke, Markus Kraemer, Markus Kraemer, Annette Walter, Antonios Bayas, Uwe K. Zettl, Ann-Sophie Lauenstein, Yavor Yalachkov, Thorleif Etgen, Matthias Kaste, Felix Luessi, Stefan Gingele, Sarah Passoke, Martin S. Weber, Jörn Peter Sieb, Axel Haarmann, Patrick Oschmann, Veit Rothhammer, Christian Geis, Markus C. Kowarik, Peter Kern, Matthias Grothe, Heike Stephanik, Klemens Angstwurm, Frank Hoffmann, Ulrike Wallwitz, Brigitte Wildemann, Sven Jarius, Jan-Patrick Stellmann, Jan-Patrick Stellmann, Jan-Patrick Stellmann, Thivya Pakeerathan, Carolin Schwake, Ilya Ayzenberg, Ingo Kleiter, Ingo Kleiter, Katinka Fischer, Orhan Aktas, Marius Ringelstein, Marius Ringelstein, Vivien Häußler, Corinna Trebst, Martin W. Hümmert

    Published 2025-04-01
    “…Time to disability milestones was estimated through Kaplan-Meier analysis and Cox proportional hazard regression models adjusted for sex, year of onset, immunotherapy exposure and antibody status. …”
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  16. 69776

    Myo-inositol affects the health, metabolome, and lactation performance of peripartum dairy cows by Chun-zheng Wang, Jia-nan Dong, Jia-nan Dong, Wu-wen Sun, Wu-wen Sun, Ke Qu, Zi-chen Lin, Natnael D. Aschalew, Natnael D. Aschalew, Yang Zhao, Zhe Sun, Zhe Sun, Zhe Sun, Na Ta, Zhi-kun Zhao, Yong-jun Liu, Yong-jun Liu, Wei-gang Zhang, Wei Zhao, Gui-xin Qin, Yu-guo Zhen, Yu-guo Zhen, Tao Wang, Tao Wang

    Published 2025-06-01
    “…Therefore, this study explored the effects of myo-inositol on the health, metabolome, and lactation performance of peripartum dairy cows using both in vitro and in vivo models.MethodsThe ANKOM RFS gas production system was used for the in vitro experiment; Twenty four healthy Holstein cows were assigned to CON group (n = 4; no supplementation of YC or myo-inositol), YC group (n = 10; 2 g/kg YC), and IN65 group (n = 10; 2 g/kg YC + 16 mg/kg myo-inositol) for in vivo experiment.ResultsThe concentrations of five volatile fatty acids (acetic acid, butyric acid, isobutyric acid, valeric acid, and isovaleric acid), and total volatile fatty acids were significantly higher in the IN65 group compared to the CON group at 6 h in vitro (P &lt; 0.01). …”
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  17. 69777
  18. 69778

    Metabolic obesity phenotypes and the risk of cancer: a prospective study of the Kailuan cohort by Xin Zheng, Xin Zheng, Xin Zheng, Xin Zheng, Yiming Wang, Yue Chen, Yue Chen, Yue Chen, Yue Chen, Yue Chen, Tong Liu, Tong Liu, Tong Liu, Tong Liu, Chenan Liu, Chenan Liu, Chenan Liu, Chenan Liu, Shiqi Lin, Shiqi Lin, Shiqi Lin, Shiqi Lin, Shiqi Lin, Hailun Xie, Hailun Xie, Hailun Xie, Hailun Xie, Xiangming Ma, Ziwen Wang, Ziwen Wang, Ziwen Wang, Ziwen Wang, Jinyu Shi, Jinyu Shi, Jinyu Shi, Jinyu Shi, Heyang Zhang, Heyang Zhang, Heyang Zhang, Heyang Zhang, Ming Yang, Ming Yang, Ming Yang, Ming Yang, Xiaoyue Liu, Xiaoyue Liu, Xiaoyue Liu, Xiaoyue Liu, Li Deng, Li Deng, Li Deng, Li Deng, Qingsong Zhang, Hanping Shi, Hanping Shi, Hanping Shi, Hanping Shi

    Published 2024-10-01
    “…This study aimed to investigate the relationship between metabolic health status combined with obesity phenotypes and the risk of cancer.MethodsData from 91,834 participants in the Kailuan cohort were analyzed, excluding individuals with a body mass index (BMI) &lt; 18.5 kg/m² and those with a history of cancer. …”
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  19. 69779

    Same data, different analysts: variation in effect sizes due to analytical decisions in ecology and evolutionary biology by Elliot Gould, Hannah S. Fraser, Timothy H. Parker, Shinichi Nakagawa, Simon C. Griffith, Peter A. Vesk, Fiona Fidler, Daniel G. Hamilton, Robin N. Abbey-Lee, Jessica K. Abbott, Luis A. Aguirre, Carles Alcaraz, Irith Aloni, Drew Altschul, Kunal Arekar, Jeff W. Atkins, Joe Atkinson, Christopher M. Baker, Meghan Barrett, Kristian Bell, Suleiman Kehinde Bello, Iván Beltrán, Bernd J. Berauer, Michael Grant Bertram, Peter D. Billman, Charlie K. Blake, Shannon Blake, Louis Bliard, Andrea Bonisoli-Alquati, Timothée Bonnet, Camille Nina Marion Bordes, Aneesh P. H. Bose, Thomas Botterill-James, Melissa Anna Boyd, Sarah A. Boyle, Tom Bradfer-Lawrence, Jennifer Bradham, Jack A. Brand, Martin I. Brengdahl, Martin Bulla, Luc Bussière, Ettore Camerlenghi, Sara E. Campbell, Leonardo L. F. Campos, Anthony Caravaggi, Pedro Cardoso, Charles J. W. Carroll, Therese A. Catanach, Xuan Chen, Heung Ying Janet Chik, Emily Sarah Choy, Alec Philip Christie, Angela Chuang, Amanda J. Chunco, Bethany L. Clark, Andrea Contina, Garth A. Covernton, Murray P. Cox, Kimberly A. Cressman, Marco Crotti, Connor Davidson Crouch, Pietro B. D’Amelio, Alexandra Allison de Sousa, Timm Fabian Döbert, Ralph Dobler, Adam J. Dobson, Tim S. Doherty, Szymon Marian Drobniak, Alexandra Grace Duffy, Alison B. Duncan, Robert P. Dunn, Jamie Dunning, Trishna Dutta, Luke Eberhart-Hertel, Jared Alan Elmore, Mahmoud Medhat Elsherif, Holly M. English, David C. Ensminger, Ulrich Rainer Ernst, Stephen M. Ferguson, Esteban Fernandez-Juricic, Thalita Ferreira-Arruda, John Fieberg, Elizabeth A. Finch, Evan A. Fiorenza, David N. Fisher, Amélie Fontaine, Wolfgang Forstmeier, Yoan Fourcade, Graham S. Frank, Cathryn A. Freund, Eduardo Fuentes-Lillo, Sara L. Gandy, Dustin G. Gannon, Ana I. García-Cervigón, Alexis C. Garretson, Xuezhen Ge, William L. Geary, Charly Géron, Marc Gilles, Antje Girndt, Daniel Gliksman, Harrison B. Goldspiel, Dylan G. E. Gomes, Megan Kate Good, Sarah C. Goslee, J. Stephen Gosnell, Eliza M. Grames, Paolo Gratton, Nicholas M. Grebe, Skye M. Greenler, Maaike Griffioen, Daniel M. Griffith, Frances J. Griffith, Jake J. Grossman, Ali Güncan, Stef Haesen, James G. Hagan, Heather A. Hager, Jonathan Philo Harris, Natasha Dean Harrison, Sarah Syedia Hasnain, Justin Chase Havird, Andrew J. Heaton, María Laura Herrera-Chaustre, Tanner J. Howard, Bin-Yan Hsu, Fabiola Iannarilli, Esperanza C. Iranzo, Erik N. K. Iverson, Saheed Olaide Jimoh, Douglas H. Johnson, Martin Johnsson, Jesse Jorna, Tommaso Jucker, Martin Jung, Ineta Kačergytė, Oliver Kaltz, Alison Ke, Clint D. Kelly, Katharine Keogan, Friedrich Wolfgang Keppeler, Alexander K. Killion, Dongmin Kim, David P. Kochan, Peter Korsten, Shan Kothari, Jonas Kuppler, Jillian M. Kusch, Malgorzata Lagisz, Kristen Marianne Lalla, Daniel J. Larkin, Courtney L. Larson, Katherine S. Lauck, M. Elise Lauterbur, Alan Law, Don-Jean Léandri-Breton, Jonas J. Lembrechts, Kiara L’Herpiniere, Eva J. P. Lievens, Daniela Oliveira de Lima, Shane Lindsay, Martin Luquet, Ross MacLeod, Kirsty H. Macphie, Kit Magellan, Magdalena M. Mair, Lisa E. Malm, Stefano Mammola, Caitlin P. Mandeville, Michael Manhart, Laura Milena Manrique-Garzon, Elina Mäntylä, Philippe Marchand, Benjamin Michael Marshall, Charles A. Martin, Dominic Andreas Martin, Jake Mitchell Martin, April Robin Martinig, Erin S. McCallum, Mark McCauley, Sabrina M. McNew, Scott J. Meiners, Thomas Merkling, Marcus Michelangeli, Maria Moiron, Bruno Moreira, Jennifer Mortensen, Benjamin Mos, Taofeek Olatunbosun Muraina, Penelope Wrenn Murphy, Luca Nelli, Petri Niemelä, Josh Nightingale, Gustav Nilsonne, Sergio Nolazco, Sabine S. Nooten, Jessie Lanterman Novotny, Agnes Birgitta Olin, Chris L. Organ, Kate L. Ostevik, Facundo Xavier Palacio, Matthieu Paquet, Darren James Parker, David J. Pascall, Valerie J. Pasquarella, John Harold Paterson, Ana Payo-Payo, Karen Marie Pedersen, Grégoire Perez, Kayla I. Perry, Patrice Pottier, Michael J. Proulx, Raphaël Proulx, Jessica L Pruett, Veronarindra Ramananjato, Finaritra Tolotra Randimbiarison, Onja H. Razafindratsima, Diana J. Rennison, Federico Riva, Sepand Riyahi, Michael James Roast, Felipe Pereira Rocha, Dominique G. Roche, Cristian Román-Palacios, Michael S. Rosenberg, Jessica Ross, Freya E. Rowland, Deusdedith Rugemalila, Avery L. Russell, Suvi Ruuskanen, Patrick Saccone, Asaf Sadeh, Stephen M. Salazar, Kris Sales, Pablo Salmón, Alfredo Sánchez-Tójar, Leticia Pereira Santos, Francesca Santostefano, Hayden T. Schilling, Marcus Schmidt, Tim Schmoll, Adam C. Schneider, Allie E. Schrock, Julia Schroeder, Nicolas Schtickzelle, Nick L. Schultz, Drew A. Scott, Michael Peter Scroggie, Julie Teresa Shapiro, Nitika Sharma, Caroline L. Shearer, Diego Simón, Michael I. Sitvarin, Fabrício Luiz Skupien, Heather Lea Slinn, Grania Polly Smith, Jeremy A. Smith, Rahel Sollmann, Kaitlin Stack Whitney, Shannon Michael Still, Erica F. Stuber, Guy F. Sutton, Ben Swallow, Conor Claverie Taff, Elina Takola, Andrew J. Tanentzap, Rocío Tarjuelo, Richard J. Telford, Christopher J. Thawley, Hugo Thierry, Jacqueline Thomson, Svenja Tidau, Emily M. Tompkins, Claire Marie Tortorelli, Andrew Trlica, Biz R. Turnell, Lara Urban, Stijn Van de Vondel, Jessica Eva Megan van der Wal, Jens Van Eeckhoven, Francis van Oordt, K. Michelle Vanderwel, Mark C. Vanderwel, Karen J. Vanderwolf, Juliana Vélez, Diana Carolina Vergara-Florez, Brian C. Verrelli, Marcus Vinícius Vieira, Nora Villamil, Valerio Vitali, Julien Vollering, Jeffrey Walker, Xanthe J. Walker, Jonathan A. Walter, Pawel Waryszak, Ryan J. Weaver, Ronja E. M. Wedegärtner, Daniel L. Weller, Shannon Whelan, Rachel Louise White, David William Wolfson, Andrew Wood, Scott W. Yanco, Jian D. L. Yen, Casey Youngflesh, Giacomo Zilio, Cédric Zimmer, Gregory Mark Zimmerman, Rachel A. Zitomer

    Published 2025-02-01
    “…We expanded the scope of this prior work by implementing a large-scale empirical exploration of the variation in effect sizes and model predictions generated by the analytical decisions of different researchers in ecology and evolutionary biology. …”
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  20. 69780

    ECM1 expression in chronic liver disease: Regulation by EGF/STAT1 and IFNγ/NRF2 signalling by Yujia Li, Chenjun Huang, Weiguo Fan, Seddik Hammad, Cyrill Géraud, Lea Berger, Shanshan Wang, Ye Yao, Chenhao Tong, Claudia Rubie, Laura Kim Feiner, Zeribe C. Nwosu, Frederik Link, Pia Erdösi, Weronika Piorońska, Kerry Gould, Christoph Meyer, Rilu Feng, Hui Liu, Chen Shao, Bing Sun, Huiguo Ding, Roman Liebe, Matthias P.A. Ebert, Honglei Weng, Matthias Glanemann, Chunfang Gao, Peter ten Dijke, Steven Dooley, Sai Wang

    Published 2025-08-01
    “…We investigated the mechanism of ECM1 regulation in hepatocytes under pathophysiological conditions. Methods: We used promoter analysis to predict Ecm1 transcriptional regulators and assessed the expression of Ecm1-related genes by single-cell RNA sequencing (scRNA-seq) and bulk RNA-seq. …”
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