Temporal association of antimicrobial use in livestock with antimicrobial resistance in non-typhoid Salmonella human infections in the Netherlands, 2008–2019 by Linda E. Chanamé Pinedo, Anouk P. Meijs, Huifang Deng, Sabine C. de Greeff, Engeline van Duijkeren, Cindy M. Dierikx, Kees T. Veldman, Pim Sanders, Maaike J.C. van den Beld, Bart Wullings, Eelco Franz, Roan Pijnacker, Lapo Mughini-Gras

“…Correlation analysis was performed to relate AMR proportions between human and broiler/pig NTS isolates. …”
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Association Between Size of Left Ventricle and Long‐Term Cardiovascular Events by Yun‐Jiu Cheng, Zi‐Li Liao, Li‐Juan Liu, Yue‐Dong Ma, Xu‐Miao Chen, Ze‐Xuan Wu, Hui‐Qiang Wei, Wei‐Dong Lin, Yi‐Jian Liao, Su‐Hua Wu, Yu‐Mei Xue, Li‐Chun Wang, Yang Wu

“…Cox proportional hazards models were applied to evaluate the association between LV size and composite cardiovascular outcomes. …”
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Regional variations in the impacts of high temperature on hospital admissions in Brazil by Huiqi Chen, Ivan Augusto Cecilio e Silva, Shakoor Hajat, Letícia Xander Russo, Kai Wan, Cherie Part, Zhifu Mi, Josephine Borghi, Dorothea Nitsch, Everton Nunes da Silva, Anna M. Foss

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Seroprevalence of SARS-CoV-2 antibodies in children of United Kingdom healthcare workers: a prospective multicentre cohort study protocol by Shamez N Ladhani, Mark David Lyttle, Derek Fairley, James McKenna, Claire Mcginn, Kathryn Ferris, Chris Watson, Hannah Mitchell, Jennifer Evans, Michael Corr, Rebecca Moore, Gala Rowe-Setz, Steven Foster, Lisa McFetridge, Sharon Christie, Julieann Maney, Michael David Shields, Tom Waterfield

“…Determining the changing seroprevalence is of vital public health importance and can help inform decisions around the lifting of paediatric specific social distancing measures such as school closures and the cancellation of routine paediatric hospital services.Methods and analysis 1000 healthy children of healthcare workers aged between 2 and 15 years will be recruited from five UK sites (Belfast, Cardiff, Glasgow, London and Manchester). …”
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Pathways From Socioeconomic Factors to Major Cardiovascular Events Among Postmenopausal Veteran and Nonveteran Women: Findings From the Women's Health Initiative by Hind A. Beydoun, May A. Beydoun, Rebecca L. Kinney, Simin Liu, Rona Yu, Matthew Allison, Robert B. Wallace, Qian Xiao, Longjian Liu, Philippe Gradidge, Su Yon Jung, Hilary A. Tindle, Shawna Follis, Robert Brunner, Jack Tsai

“…Using generalized structural equations modeling coupled with survival analysis techniques, we estimated the effects of SES on major CVD events through smoking, body mass index, comorbidities, cardiometabolic risk factors, and self‐rated health, controlling for WHI component, region, age, race, ethnicity, marital status, and health care provider access. …”
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Recommendations for a Communication Strategy to Support Informed Decision‐Making About Self or Clinician Sampling for Cervical Screening in the UK: Qualitative Study by Denitza Williams, Eleanor Clarke, Kate J. Lifford, Lindsay Haywood, Fiona Wood, Jo Waller, Adrian Edwards, Natalie Joseph‐Williams, Caroline Evans, Gareth Powell, Rhiannon Phillips, Andrew Carson‐Stevens, Katie Walbeoff, Ardiana Gjini, Kate Brain

“…They advised on recruitment, participant facing documents and were involved in analysis.…”
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Lupus nephritis and U1-RNP-antibodies are associated with low bone mineral density and osteoporosis in patients with systemic lupus erythematosus: baseline findings in a sub-cohort... by Edgar Wiebe, Elisa Celine Schilling, Dörte Huscher, Andriko Palmowski, Zhivana Boyadzhieva, Sandra Hermann, Burkhard Muche, Mirella Lopez Picazo, Gerhard Krönke, Falk Hiepe, Tobias Alexander, Frank Buttgereit

“…We used multivariable linear and logistic regression models to identify BMD- and osteoporosis-related factors. …”
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Trends and inequalities in the nutritional status of adolescent girls and adult women in sub-Saharan Africa since 2000: a cross-sectional series study by Serge M A Somda, Abdoulaye Maïga, Safia S Jiwani, Cheikh Mbacké Faye, Shelley Walton, Tome Ca, Richard Kumapley, Giovanna Gatica-Domínguez, Elizabeth Hazel, Inacio Crochemore-Silva, Barbara Baille, Sujata Bose, William K Bosu, Kofi Busia, Ferima Coulibaly-Zerbo, Vrinda Mehra, Roosmarijn Verstraeten

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Effective and ineffective psychological adjustment in breast cancer patients before receiving neoadjuvant chemotherapy: insights from a cohort study by Majid Omari, Salima Kriya, Sara Nadi, Ghita Zerhouni, Chaymae El Abbas, Achraf El Asri, Zineb Benbrahim, Nawfel Mellas, Karima El Rhazi, Mohammed El Amine Ragala, Jaouad El Hilaly, Karima Halim, Lamiae Amaadour, Btissame Zarrouq

“…Univariate and multivariate linear regression modelling was carried out using a forward “enter” regression procedure. …”
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Distinctive Effects of Fullerene C₆₀ and Fullerenol C₆₀(OH)₂₄ Nanoparticles on Histological, Molecular and Behavioral Hallmarks of Alzheimer’s Dise... by Sholpan Askarova, Kseniia Sitdikova, Aliya Kassenova, Kirill Chaprov, Evgeniy Svirin, Andrey Tsoy, Johannes de Munter, Anna Gorlova, Aleksandr Litavrin, Aleksei Deikin, Andrey Nedorubov, Nurbol Appazov, Allan Kalueff, Anton Chernopiatko, Tatyana Strekalova

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Text message intervention delivered from Australian general practices to improve breast cancer survivors’ physical activity and cardiovascular risk factors: protocol for the EMPOWE... by Karice K Hyun, Christine Mitchell, Julie Redfern, Nashid Hafiz, Rebecca Raeside, Brooke Nickel, Carolyn Ee, Jennifer McIntosh, Elisabeth Elder, Raymond J Chan, David Mizrahi, Stephanie R Partridge, Anna C Singleton, Allyson Ruth Todd, Kirsty E Stuart

“…This randomised controlled trial (RCT) aims to evaluate the effectiveness and implementation of a text message intervention called EMPOWER-SMS-GP in Australian general practices.Methods and analysis Multi-centre single-blind hybrid I RCT (n=678; 1:1 allocation) comparing EMPOWER-SMS-GP (n=339) to usual care (n=339) at 6 months (postintervention), 12, 18 and 24 months (maintenance) and parallel mixed-methods process evaluation using the Reach, Effectiveness, Adoption, Implementation and Maintenance framework. …”
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Understanding one health challenges in marginalized urban settings: A patient and public involvement (PPI) approach from the CHIP consortium activities across four global cities by Logan Manikam, Darlington David Faijue, Kalpita Shringarpure, Margi Sheth, Pam Factor-Livak, Priti Parikh, Hector Altamirano-Medina, Dewi Nur Aisyah, Radhika Sharma, Hemant Chaturvedi, Kaushik Sarkar, Rajib Dasgupta, Nancy Hiu Lan Leung, Pradeep Kumar Srivastava, Monica Lakhanpaul

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Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells by Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu

“…We investigated the biological functions of JAG2 in immune evasion using in vitro co‐culture systems, flow cytometry, tumor‐bearing mouse models, and PDTOs. Results JAG2+ TANs expressed elevated levels of immunosuppressive molecules, including programmed cell death ligand 1 and CD14, and had independent prognostic value for the overall survival of patients with HGSOC. scRNA‐seq analysis revealed that JAG2+ TANs exhibited a terminally mature phenotype. …”
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Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10 by Bernard A Fox, Cristina Bergamaschi, George N Pavlakis, Antonio Valentin, Jenifer Bear, Barbara K Felber, Shawn M Jensen, Hrishikesh Pandit, Bethany A Nagy, Dimitris Stellas, Maggie Cam

“…Bioactive IL-15 is produced in the body as a heterodimeric cytokine, comprising the IL-15 and IL-15 receptor alpha chains (hetIL-15). Several preclinical models support the antitumor activity of hetIL-15 promoting its application in clinical trials.Methods The antitumor activity of hetIL-15 produced from mammalian cells was tested in mouse tumor models (MC38 colon carcinoma and TC-1 epithelial carcinoma). …”
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Socio‐economic status and adherence to HIV preventive and therapeutic interventions: exploring the mediating role of food insecurity among men who have sex with men and transgender... by Paula M. Luz, Thiago S. Torres, Victor C. Matos, Giovanna G. Costa, Brenda Hoagland, Cristina Pimenta, Marcos Benedetti, Beatriz Grinsztejn, Valdilea G. Veloso

“…Two structural equation models were used to assess the direct and indirect effects of variables on ART adherence among PLWH and on PrEP adherence among people using PrEP. …”
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Therapeutic potential of T-cell receptor targeting the HLA-A*11:01-restricted KRASG12V neoantigen without cross-recognition of the self-antigen RAB7B in solid tumors by Wang Wang, Jingjing Huang, Yanan Hao, Lin Zou, Xiaxia Han, Tong Chen, Meiying Shen, Bozhi Wang, Luo Li, Siyin Chen, Shengchun Liu, Xiaojian Han, Aishun Jin

“…In vivo antitumor efficacy of TCR-T cells was tested in xenograft mouse models of solid tumors.Results The analysis of HLA binding properties for public neoantigens revealed that HLA-A*11:01-presented KRASG12V epitopes exhibited the strongest HLA binding stability. …”
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Mechanisms of Cefiderocol Resistance in Carbapenemase-Producing Enterobacterales: Insights from Comparative Genomics by Alexander Tristancho-Baró, Ana Isabel López-Calleja, Ana Milagro, Mónica Ariza, Víctor Viñeta, Blanca Fortuño, Concepción López, Miriam Latorre-Millán, Laura Clusa, David Badenas-Alzugaray, Rosa Martínez, Carmen Torres, Antonio Rezusta

“…Whole-genome sequencing, variant annotation, structural modelling, and pangenome analysis were performed to characterize resistance mechanisms. …”
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Dose–response study of a fenugreek-based antibiotic alternative in Bábolna Tetra-SL chicks (1–42 days old) with mixed bacterial infections by Ádám Kerek, Ádám Kerek, Ábel Szabó, Péter Ferenc Dobra, Krisztina Bárdos, Krisztina Bárdos, Bettina Paszerbovics, Zsófia Bata, Viviána Molnár-Nagy, Ákos Jerzsele, Ákos Jerzsele, László Ózsvári, László Ózsvári

“…Because of this, there is an urgent need for safe and effective alternatives in animal husbandry.MethodsThis study aimed to perform an in vivo the dose–response analysis of fenugreek (Trigonella foenum-graecum), as a plant-based antibiotic alternative feed supplement in Bábolna Tetra-SL chicks (1–42 days old) with a 1:1 sex ratio. …”
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Historical overview, advancements, and future prospects of coalfield structure research in China by Daiyong CAO, Yiwen JU, Yucheng XIA, Bo JIANG, Shuzheng NING, Yingchun WEI, Anmin WANG, Xiaoming LI, Wenfeng ZHAN, Huantong LI, Lu WANG, Zhuocheng CAI

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The Impact of Digital Technology–Based Exercise Combined With Dietary Intervention on Body Composition in College Students With Obesity: Prospective Study by Chengyuan Hu, Zixin Lv, Jieping Zhu, Chunyuan Lai, Dongjuan Guo, Maolin Chen, Xiaoyan Cheng, Mingxin Rao, Xinyou Zhou, Liqiang Su

“…Linear mixed effects models showed that the sex and diet interaction significantly affected subcutaneous fat mass (P=.02). …”
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