Enhancing emotion regulation with an in situ socially assistive robot among LGBTQ+ youth with self-harm ideation: protocol for a randomised controlled trial by Chris Hollis, Kareem Khan, Peter Fonagy, Rohan Borschmann, Cathy Creswell, Kapil Sayal, Nitish Jawahar, A Jess Williams, Ellen Townsend, Dorothee Auer, Praveetha Patalay, Yvonne Kelly, Christopher R Tench, Paul Stallard, Louise Arseneault, Sieun Lee, Sally Merry, Charlotte Hall, Jo Gregory, Rory O’Connor, Emma Nielsen, Edmund Sonuga-Barke, Seonaid Cleare, James Gross, Amelia Chapman-Nisar, Nkem Naeche, Petr Slovak, Emily Lloyd, Josimar De Alcantara Mendes, Carolyn Ten Holter, Marina Jirotka, Zsofia Lazar, Aaron Kandola, Sonia Livingstone, Kasia Kostryka-Allchorne, Jake Bourgaize, Mariya Stoilova, Marianne Etherson, Chris Greenhalgh, Jim Warren, Vajisha Wanniarachchi, Kevin Glover, Mathijs Lucassen, Karolina Stasiak, Camilla Babbage, Adam Parker, Joanna Lockwood, Elvira Perez Vallejos, Rebecca Woodcock, Sarah Doherty, Lucy-Paige Willingham

“…The present study is designed to evaluate the impact of access to Purrble among LGBTQ+ youth who have self-harmful thoughts, when compared with waitlist controls.Methods and analysis The study is a single-blind, randomised control trial comparing access to the Purrble robot with waitlist control. …”
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Interprofessional Differences in Multidimensional Self-Efficacy Associated With Professional Performance in Nephrology During Case-Based Learning by Chia-Ter Chao, Mei-Yi Wu, Kuan-Yu Hung, Mai-Szu Wu, Jyh-Chong Liang

“…We undertook confirmatory factor analysis (CFA), followed by structural equation modeling (SEM) to evaluate associations between 5 dimensions of learning SE (conceptual understanding [CU], higher-order cognitive skills [HC], practical work [PW], everyday application [EA], and medical science communication [MSC]) and their professional SE in nephrology according to participants' medical professions. …”
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FGFR2 identified as a NETs-associated biomarker and therapeutic target in diabetic foot ulcers by Linrui Dai, Shunli Rui, Mengling Yang, Shiyan Yu, Qingqing Chen, Hongyan Wang, Bo Deng, Liling Deng, Wei Hao, Xiaohua Wu, David G. Armstrong, Zhidong Cao, Xiaodong Duan, Wuquan Deng

“…FGFR2 expression was significantly reduced in DFU tissues across all datasets and in our experimental models, where its downregulation correlated with increased NETs accumulation. …”
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Obesity and outcomes after elective thoracoabdominal aortic aneurysm repairCentral MessagePerspective by Sanford Zeigler, MD, Kyle W. Blackburn, BS, Ahmad Tabatabaeishoorijeh, BS, Veronica A. Glover, PhD, Susan Y. Green, MPH, Marc R. Moon, MD, Scott A. LeMaire, MD, Joseph S. Coselli, MD

“…Multivariable logistic regression modeling identified predictors of operative mortality in patients with obesity. …”
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Examining the social distributions in neighbourhood black carbon and ultrafine particles in Montreal and Toronto, Canada by Emmanuelle Batisse, Marshall Lloyd, Alicia Cavanaugh, Arman Ganji, Junshi Xu, Marianne Hatzopoulou, Jill Baumgartner, Scott Weichenthal

“…Final exposure surfaces were generated by integrating predictions from land-use regression models and deep convolutional neural network models. …”
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Impact of DNA‐Methylation Age Acceleration on Long‐Term Mortality Among US Adults With Cardiovascular‐Kidney‐Metabolic Syndrome by Shuang Wu, Jun Zhu, Siqi Lyu, Juan Wang, Xinghui Shao, Han Zhang, Ziyi Zhong, Hongyu Liu, Lihui Zheng, Yang Chen

“…The primary outcome was all‐cause mortality, with cardiovascular and noncardiovascular mortality as secondary outcomes. Proportional odds models assessed the associations between DNAmAAs and CKM stages, and Cox proportional hazards regression models estimated the associations between DNAmAAs and mortality. …”
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Primary lymphomas of the genitourinary tract: A population-based study by Carlotta Palumbo, Elio Mazzone, Francesco A. Mistretta, Sophie Knipper, Zhe Tian, Paul Perrotte, Francesco Montorsi, Shahrokh F. Shariat, Fred Saad, Claudio Simeone, Alberto Briganti, Alessandro Antonelli, Pierre I. Karakiewicz

“…Estimated annual proportion change methodology (EAPC), multivariable logistic regression models, cumulative incidence plots and multivariable competing risks regression models were used. …”
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High-resolution spatiotemporal measurement of air and environmental noise pollution in Sub-Saharan African cities: Pathways to Equitable Health Cities Study protocol for Accra, Gha... by Michael Brauer, Majid Ezzati, Sierra N Clark, Abosede S Alli, Jill Baumgartner, Mireille B Toledano, Allison F Hughes, James Nimo, Josephine Bedford Moses, Solomon Terkpertey, Jose Vallarino, Samuel Agyei-Mensah, Ernest Agyemang, Ricky Nathvani, Emily Muller, James Bennett, Jiayuan Wang, Andrew Beddows, Frank Kelly, Benjamin Barratt, Sean Beevers, Raphael E Arku

“…We will use state-of-the-art methods, including spatial statistics, deep/machine learning, and processed-based emissions modelling, to capture highly resolved temporal and spatial variations in pollution levels across the GAMA and to identify their potential sources. …”
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Simplified Physical Stability Assessment of Chilean Mine Waste Storage Facilities Using GIS and AI: Application in the Antofagasta Region by Gabriel Hermosilla, Gabriel Villavicencio, Giovanni Cocca-Guardia, Vicente Aprigliano, Manuel Silva, Juan Carlos Quezada, Pierre Breul, Vinicius Minatogawa, Jaime Morales

“…The National Service of Geology and Mining (SERNAGEOMIN) requires assessment of the physical stability (PS) of these facilities, but current methods are hindered by data scarcity and resource constraints. …”
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Mediating role of systemic immune-inflammation index between heavy metal exposure and hepatic steatosis/hepatic fibrosis: evidence from NHANES 2005–2020 by Ningning Wang, Ningning Wang, Ningning Wang, Xuying Li, Xuying Li, Xuying Li, Rui He, Rui He, Xiujuan Zheng, Xiujuan Zheng, Xiujuan Zheng, Mingqi Li, Mingqi Li, Mingqi Li, Shijing Nian, Shijing Nian, Shijing Nian, Kewei Wang, Kewei Wang, Kewei Wang

“…Partial correlation analysis, weighted linear regression, weighted quantile sum (WQS) regression, and mediation effect models were used in the study.ResultsSII showed significant negative correlations with hepatic fibrosis markers (FIB-4: r = −0.290; NFS: r = −0.382, both P < 0.001) but no association with hepatic steatosis indices. …”
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Higher levels of oxidative balance score linked to lower risk of gallstones: findings from the 2017–2020 National Health and Nutrition Examination Survey by Ting Xiong, Ting Xiong, Ting Xiong, Zhonghuo Chen, Zhonghuo Chen, Zhonghuo Chen, Jianwei Yi, Jianwei Yi, Jianwei Yi, Taozhi Yu, Taozhi Yu, Taozhi Yu, Kai Wang, Kai Wang, Kai Wang, Kai Wang

“…Weighted logistic regression models were applied to examine the association between OBS and the prevalence of gallstones, complemented by subgroup and sensitivity analyses. …”
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Chemical composition, antimicrobial, and antioxidant properties of essential oils from Artemisia herba-alba asso. and Artemisia huguetii caball. from Morocco: in vitro and in silic... by Mohamed El Ouardi, Mohamed El Ouardi, Aziz Drioiche, Aziz Drioiche, Fadoua El Makhoukhi, Fadoua El Makhoukhi, Jamal Mabrouki, Mohammed Hakmi, Omkulthom Al kamaly, Bshra A. Alsfouk, Brahim Eddamsyry, Hamid Khamar, Touriya Zair, Mohammed Alaoui El Belghiti

“…In silico predictions of antibacterial and antioxidant activities were performed using computational models.ResultsThe extraction yields varied depending on the geographical origin, ranging from 1.54% to 2.78%. …”
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Leukocyte Count in Solid Organ Transplant Recipients After SARS-CoV-2 mRNA Vaccination and Infection by Marita Kern, Sebastian Rask Hamm, Christian Ross Pedersen, Dina Leth Møller, Josefine Amalie Loft, Rasmus Bo Hasselbalch, Line Dam Heftdal, Mia Marie Pries-Heje, Michael Perch, Søren Schwartz Sørensen, Allan Rasmussen, Peter Garred, Kasper Karmark Iversen, Henning Bundgaard, Caroline A. Sabin, Susanne Dam Nielsen

“…We aimed to describe the prevalence and relative incidence of decreased leukocyte counts and changes in leukocyte counts before and after SARS-CoV-2 mRNA vaccination and SARS-CoV-2 infection in SOT recipients. Methods: Changes in leukocyte counts from before to after each vaccine dose were investigated using linear mixed models. …”
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Nestin Regulates Autophagy‐Dependent Ferroptosis Mediated Skeletal Muscle Atrophy by Ubiquitinating MAP 1LC3B by Shunshun Han, Xiyu Zhao, Chunlin Yu, Can Cui, Yao Zhang, Qing Zhu, Mohan Qiu, Chaowu Yang, Huadong Yin

“…Ferroptosis, an iron‐dependent form of programmed cell death driven by lipid peroxidation, has been implicated in various diseases, but its role in skeletal muscle atrophy remains unclear. Methods Ferroptosis in skeletal muscle atrophy was investigated using two models: dexamethasone (Dex)‐induced atrophy (n = 6 independent cell cultures per group) and simulated microgravity (n = 6 mice per group). …”
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Harnessing multi-omics and artificial intelligence: revolutionizing prognosis and treatment in hepatocellular carcinoma by Zhen Wang, Zhen Wang, Zhen Wang, Gangchen Zhou, Gangchen Zhou, Rongchuan Cao, Rongchuan Cao, Guolin Zhang, Guolin Zhang, Yongxu Zhang, Yongxu Zhang, Mingyue Xiao, Longbi Liu, Longbi Liu, Xuesong Zhang

“…Furthermore, machine learning models were employed to develop the artificial intelligence-derived risk score (AIDRS) with the aim of predicting patient outcomes and guiding personalized therapy. …”
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Team climate, job satisfaction, burnout and practice performance: results of a national survey of staff in general practices in England by Peter Williams, Heather Gage, Bridget Jones, Carole Aspden, Jessica Smylie, Thomas Bird, Morro M. L. Touray, Phelim Brady, John Campbell, Rupa Chilvers, Catherine Marchand, Stephen Peckham, Suzanne H. Richards, Karen Spilsbury, Mark Joy, Simon de Lusignan

“…Practices in which over 50% of staff participated were included in modelling of practice level outcomes. Results A total of 9835 individual members of staff from 809 practices participated. …”
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Exposure to persistent organic pollutants and sarcopenia: Revealing associations, mediated modifications, and potential mechanisms by Jinlong Tao, Jinchan Zhai, Jiaqi Yang, Qiang Niu, Yunhua Hu, Yizhong Yan

“…Results: The WQS index for mixed POPs exposure was inversely associated with sarcopenia, with PCB146 contributing the most. In BKMR models, PFHS (PIP=0.65) was the top contributor to sarcopenia risk In separate WQS regression models, exposure to PCBs and PBDEs was significantly inversely associated with the risk of sarcopenia, with odds ratios (ORs) of 0.66 (95 % CI: 0.46, 0.96) and 0.74 (95 % CI: 0.57, 0.98), respectively. …”
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Prenatal exposure to polyfluoroalkyl substances and visual acuity in preschool children: Findings from the Guangxi Zhuang birth cohort in China by Lidi Lei, Fangfang Lv, Peini Lu, Caimei Mo, Jinxiu Li, Xuemei Xu, Gangjie Wei, Xuanqian Huang, Xiaoqiang Qiu, Dongping Huang, Xiaomei Zhou, Hui Wei, Xiaoyun Zeng, Shun Liu

“…Multiple linear regression models and logistic regression models were performed to study the single effects of individual PFAS on VA and visual impairment (VI), respectively. …”
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Retinal biomarkers for the risk of Alzheimer’s disease and frontotemporal dementia by Ruihan Wang, Jiajie Cai, Yuzhu Gao, Yingying Tang, Hui Gao, Linyuan Qin, Hanlin Cai, Feng Yang, Yimeng Ren, Caimei Luo, Shiyu Feng, Hongbo Yin, Ming Zhang, Chunyan Luo, Qiyong Gong, Xiong Xiao, Qin Chen

“…Cox proportional hazards models were used to estimate the associations between macular OCT parameters and the risk of AD and FTD. …”
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Enhancing pancreatic cancer treatment: the role of H101 oncolytic virus in irreversible electroporation by Pu Xi, Dejun Zeng, Miao Chen, Lingmin Jiang, Yu Zhang, Dailei Qin, Zehui Yao, Chaobin He

“…Experiments using mouse subcutaneous tumor models confirmed that the combination therapy significantly reduced tumor growth. …”
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