Whole-transcriptome sequencing reveals the global molecular responses and ceRNA regulatory network involved in programmed cell death of rice cultivars zyk639 and zyk-lm by Haipeng Zhang, Han Zheng, Weifang Liang, Junjie Zhang, Hongyu Zhao, Jianzhong Li, Yujie Zhou, Liujie Xie, Chulang Yu, Binfeng Dai, Liequan Zhong, Fan Hou, Chengyu Wang, Jianping Chen, Yong Yang

“…Besides, these data were used for weighted gene co-expression analysis (WGCNA) and construction of competitive endogenous RNAs (ceRNAs). …”
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Impact of Vascular Geometry on Thrombosis in Pediatric Patients With Modified Blalock‐Taussig‐Thomas Shunt: A Pilot Study by Ethan Penn, Yi Qiao, Kimsey Platten, Scott M. Bugenhagen, Ram Rohatgi, Jacob R. Miller, Jiaxiao Fang, Kelsey Mercer, Blaire Kulp, Jinli Wang, Guy M. Genin, David Bark, Edon J. Rabinowitz

“…Methods and Results We retrospectively analyzed 11 infants with hypoplastic left heart syndrome who underwent mBTTS placement. …”
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Genomic epidemiology and public health implications of zoonotic monophasic Salmonella Typhimurium ST34 by Xiaolei Wu, Jiaxin Du, Xiao Zhou, Xianqi Peng, Chenghao Jia, Baikui Wang, Beibei Wu, Yan Li, Yan Li, Min Yue, Min Yue, Min Yue

“…This study aims to fill this crucial gap by assessing the genomic epidemiology of multidrug resistance (MDR) mSTM ST34, as well as its clinical characteristics and virulence.MethodsTo achieve the objectives of this study, we conducted a comprehensive genomic analysis of mSTM ST34 isolates. …”
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Baseline kidney function and the effects of dapagliflozin on health status in heart failure in DEFINE‐HF and PRESERVED‐HF by Andrew P. Ambrosy, Andrew J. Sauer, Shachi Patel, Sheryl L. Windsor, Barry A. Borlaug, Mansoor Husain, Silvio E. Inzucchi, Dalane W. Kitzman, Darren K. McGuire, Sanjiv J. Shah, Kavita Sharma, Guillermo Umpierrez, Mikhail N. Kosiborod

“…This study aimed to assess whether the treatment effects of dapagliflozin on health status vary based on estimated glomerular filtration rate (eGFR). Methods and Results We conducted a pooled participant‐level analysis of two double‐blind, randomized trials, DEFINE‐HF (n = 236) and PRESERVED‐HF (n = 324), which evaluated dapagliflozin versus placebo. …”
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Exploiting <i>Wolbachia</i> as a Tool for Mosquito-Borne Disease Control: Pursuing Efficacy, Safety, and Sustainability by Riccardo Moretti, Jue Tao Lim, Alvaro Gil Araujo Ferreira, Luigi Ponti, Marta Giovanetti, Chow Jo Yi, Pranav Tewari, Maria Cholvi, Jacob Crawford, Andrew Paul Gutierrez, Stephen L. Dobson, Perran A. Ross

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Synergistic effects of Bacillus subtilis QST 713 and L-arginine supplementation during late gestation on reproductive performance in Landrace × Yorkshire sows: A randomized control... by Thepsavanh Khoudphaithoune, Do Thi Kim Lanh, Nguyen Van Thanh, Bui Van Dung, Peerapol Sukon, Nguyen Hoai Nam

“…Linear and generalized linear mixed models were used for analysis. Results: Co-supplementation with B. subtilis and L-arginine significantly increased IBW (1434.7 g vs. 1310.0 g, p < 0.001), TBW (19.6 kg vs. 16.9 kg, p < 0.001), NBABW (18.1 kg vs. 15.9 kg, p = 0.006), and the proportion of large piglets (33.7% vs. 19.5%, p = 0.0002), while reducing runt piglet incidence (4.0% vs. 14.4%, p < 0.001). …”
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Federally qualified health center patients’ experiences with remote patient monitoring as part of telehealth services for self-measured blood pressure monitoring by Natalia I. Heredia, Maria E. Fernandez, Ella R. Garza, Jabria Pittman, Fernanda Velasco-Huerta, Tracy L. Judd, Jocelyn Hunyadi, Elvis Longanga Diese, Deevakar Rogith, William B. Perkison, Susan H. Fenton

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Application of artificial intelligence-assisted Traditional Chinese medicine formula granules in bone and joint degenerative diseases in the field of holistic health by Xian-Quan Zhang, Xian-Quan Zhang, Xian-Quan Zhang, Xing-De Wei, Zhuo-Xu Gu, Guang-Hui Zhou, Chu-Jia Huang, Ming-Hui Luo, Ling-Feng Zeng, Ling-Feng Zeng, Ling-Feng Zeng, Wei-Yi Yang, Wei-Yi Yang

“…Traditional treatment methods face bottlenecks in long-term management, including drug side effects and low patient compliance. …”
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Anti-stigma campaign: the COVID-19 stigma and associated factors among Chinese young students by Cong Wang, Cong Wang, Yun-Fei Mu, Yun-Fei Mu, Jia Cai, Yu Wang, Zhong-Yue Deng, Zhong-Yue Deng, Ai-Ping Deng, Ai-Ping Deng, Hong-Jun Song, Hong-Jun Song, Tian-Ming Zhang, Xin-Yi Zhao, Yi-Yue Yang, Li Yin, Yi Huang, Yi Huang, Jian-Jun Luo, Mao-Sheng Ran, Mao-Sheng Ran

“…Logistic regression analysis identified risk factors for stigma, while Random Forest (RF) modeling ranked the importance of these factors.Results20,155 (24.3%) participants reported stigmatizing views toward COVID-19 patients. …”
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U-shaped association between ultra-processed food intake and overactive bladder in US adults: a national cross-sectional study by Zufa Zhang, Zufa Zhang, Li Chen, Long Lv, Long Lv, Wenkai Li, Wenkai Li, Bin Hou, Bin Hou, Sheng Guan, Sheng Guan, Zuyi Chen, Zuyi Chen, Danni He, Danni He, Hongxuan Song, Hongxuan Song, Weibing Sun, Weibing Sun, Feng Tian, Feng Tian, Fengze Jiang, Fengze Jiang, Sixiong Jiang, Sixiong Jiang

“…This study aimed to investigate the relationship between UPF consumption and the risk of OAB in U.S. adults.MethodsWe conducted a cross-sectional analysis using data from 23,482 participants in the National Health and Nutrition Examination Survey (NHANES). …”
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Association of advanced glycation end-product accumulation with overactive bladder in community-dwelling elderly: A cross-sectional Sukagawa study by Kenji Omae, Noriaki Kurita, Sei Takahashi, Shingo Fukuma, Yosuke Yamamoto, Shunichi Fukuhara

“…Objective: This study aimed to evaluate the influence of advanced glycation end-product (AGE) accumulation on the prevalence and severity of overactive bladder (OAB) in community-dwelling elderly adults. Methods: We conducted a cross-sectional study involving 269 Japanese community dwellers aged ≥75 years in 2015. …”
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Oxidative balance and survival in osteoporosis: how antioxidant diets and lifestyles reduce mortality risk by Ziyao Ding, Ziyao Ding, Ziyao Ding, Haixu Qi, Haixu Qi, Haixu Qi, Wenbo Li, Wenbo Li, Wenbo Li, Changchang Chen, Youwei Li, Jun Sun, Jun Sun, Maji Sun, Maji Sun, Maji Sun, Shuo Feng, Shuo Feng, Shuo Feng, Feng Yuan, Feng Yuan, Feng Yuan

“…This research aims to investigate the correlation between oxidative balance score (OBS) and all-cause mortality in individuals diagnosed with OP.MethodsThis study is based on data from the National Health and Nutrition Examination Survey (NHANES, 2005–2018), which covers 776 OP patients aged 50 or older. …”
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Late Immune-Related Adverse Events After At Least Two Years of Immune Checkpoint Inhibitor Therapy: Incidence and Association With Survival in Patients With Advanced NSCLC by Omar Elghawy, MD, Adam Barsouk, MD, Jonathan H. Sussman, BS, Benjamin A. Bleiberg, MD, Lauren Reed-Guy, MD, Christopher D’Avella, MD, Aditi Singh, MD, Christine Ciunci, MD, MSCE, Kyle Robinson, MD, John Kosteva, MD, Corey Langer, MD, Roger B. Cohen, MD, Charu Aggarwal, MD, MPH, Melina Marmarelis, MD, MSCE, Lova Sun, MD, MSCE

“…Background: Limited data are available on late immune-related adverse events (IRAEs) in patients with metastatic NSCLC receiving immunotherapy (ICI) beyond 2 years. Methods: A single-institution retrospective analysis including patients who received longer than 2 years of ICI therapy for metastatic NSCLC between 2012 and 2023 was performed. …”
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Uncovering pyrethroid resistance mechanisms in Anopheles punctulatus group mosquitoes: A novel insight from Keerom, Papua, Indonesia by Lepa Syahrani, Puji B. S. Asih, Ismail E. Rozi, Astari Dwiranti, Dendi H. Permana, Irdayanti Irdayanti, Anom Bowolaksono, Din Syafruddin

“…Allele frequencies were analyzed using Hardy–Weinberg equilibrium models, and statistical comparisons were made using one-way analysis of variance. …”
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Early onset neonatal bloodstream infections in South African hospitals by Genevieve Theron, Adrie Bekker, Larisse Bolton, Andrew Whitelaw, Arnoldus Engelbrecht, Louisa Erasmus, Aaqilah Fataar, Chandre Geldenhuys, Marlize Kunneke, Dave Le Roux, Natasha O’Connell, Kessendri Reddy, Natasha Rhoda, Lloyd Tooke, Mark Wates, Thandi Wessels, Angela Dramowski

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Effect of an Energy-Restricted Mediterranean Diet, Physical Activity and Behavioral Support Lifestyle Intervention on Body Composition in Older Adults with Metabolic Syndrome: Thre... by Dora Romaguera, Miguel Ruiz-Canela, J. Alfredo Martínez, Vicente Martín, Ramón Estruch, Jordi Salas-Salvadó, Jadwiga Konieczna

“…The potential interactions of study arm with time were tested in crude and multivariable linear-mixed effects models with repeated measurements at baseline and at 1 and 3 years. …”
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Plasma lipidomics profile in pregnancy and gestational diabetes risk: a prospective study in a multiracial/ethnic cohort by Yeyi Zhu, Cuilin Zhang, Paul S Albert, Mohammad L Rahman, Fasil Tekola-Ayele, Michael Y Tsai, Xiaobin Wang, Yen-Chen A Feng, Oliver Fiehn, Liming Liang

“…We constructed lipid networks using weighted correlation network analysis technique. We examined prospective associations of lipid networks and individual lipids with GDM risk using linear mixed effect models. …”
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Rescue Antenatal Corticosteroids in Late Preterm Birth after Completion of the Initial Cycle of Antenatal Corticosteroids during the Early Preterm Period by Da Eun Jeong, Jung Yun Lee, Eun Ji Oh, Kyong-No Lee, Hyunsu Kim, Hyeon Ji Kim, Jee Yoon Park, Young Hwa Jung, Kyung Joon Oh, Chang Won Choi

“…Statistical analyses, including logistic regression and multivariate modeling, were performed to assess the association between rescue ACS and neonatal outcomes. …”
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Remnant–to–LDL cholesterol discordance as a predictor of thromboembolic events in anticoagulated patients with atrial fibrillation: a report from the prospective Murcia AF project... by Eva Soler-Espejo, Yang Chen, José Miguel Rivera-Caravaca, María Pilar Ramos-Bratos, Raquel López-Gálvez, Francisco Marín, Vanessa Roldán, Gregory Y.H. Lip

“…In the low LDL-C group, RCS analysis showed a significant linear association between RC levels and thromboembolic risk (p-overall = 0.044). …”
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Gut microbiota remodeling exacerbates neuroinflammation and cognitive dysfunction via the microbiota-gut-brain axis in prenatal VPA-exposed C57BL/6 mice offspring by Zhaoming Liu, Zhaoming Liu, Caixia Wu, Caixia Wu, Zhaojian Sun, Zuoxian Lin, Yirong Sun, Nouman Amjad, Muhammad Majid, Rajesh Basnet, Zhiyuan Li, Zhiyuan Li, Zhiyuan Li

“…Emerging evidence implicates the microbiota-gut-brain axis as a critical mediator of neuroinflammation and cognitive deficits, but causal pathways in VPA-induced ASD models require systematic exploration. This study investigates how prenatal VPA exposure reshapes gut microbiota composition, exacerbates neuroinflammatory responses, and drives cognitive dysfunction through the microbiota-gut-brain axis in C57BL/6 mouse offspring.MethodsPrenatal VPA-exposed and control offspring underwent behavioral assessments (open field, three-chamber social interaction, marble-burying, and Morris water maze tests). …”
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