Nuclear Excitation of 181Ta Induced by High Power Femtosecond Laser Pulses by XU Yongsheng1, HE Chuangye1, LAN Xiaofei2, ZHAO Baozhen1

“…The findings contribute to a better understanding of the underlying physical mechanisms and highlight the potential for further optimization of experimental methods and theoretical models. Future studies are recommended to refine detection techniques and explore the influence of different plasma parameters on nuclear excitation yields. …”
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Observational study comparing the accuracy/variability between the ERSPC and the PCPT risk calculators for the prediction of significant prostate cancer in patients with PSA by Enrique Gomez Gomez, Juan José Salamanca Bustos, Julia Carrasco Valiente, Jose Luis Fernandez Rueda, Ana Blanca, José Valero Rosa, Ines Bravo Arrebola, Javier Marquez López, Juan Manuel Jimenez Vacas, Maria José Requena Tapia, Raul Miguel Luque

“…Discriminative ability for SigPCa was similar between models with an AUC=0.73 (0.68–0.79) for ERSPC-RC versus 0.73 (0.67–0.79) for PCPT-RC. …”
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Immune and Inflammation Markers as a Predictor of Overall Survival in Patients with Hematologic Malignancies: A Retrospective Cohort Study by Mehmet Ali Ucar, Anıl Tombak, Aydın Akdeniz, Hüseyin Derya Dinçyürek, Meryem Şener, Mahmut Bakır Koyuncu, Eyüp Naci Tiftik, Recep Dokuyucu

“…Overall survival was analyzed using Kaplan–Meier curves and Cox proportional hazards models, adjusted for age, sex, malignancy type, and disease stage. …”
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Mediating roles of preterm birth and restricted fetal growth in the relationship between maternal education and infant mortality: A Danish population-based cohort study. by Yongfu Yu, Zeyan Liew, Aolin Wang, Onyebuchi A Arah, Jialiang Li, Jørn Olsen, Sven Cnattingius, Guoyou Qin, Carsten Obel, Bo Fu, Jiong Li

“…We aimed to explore whether and the extent to which preterm birth (PTB) and small for gestational age (SGA) at birth mediate the association between maternal education and infant mortality.<h4>Methods and findings</h4>We developed a population-based cohort study to include all 1,994,618 live singletons born in Denmark in 1981-2015. …”
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<i>C11orf58</i> (Hero20) Gene Polymorphism: Contribution to Ischemic Stroke Risk and Interactions with Other Heat-Resistant Obscure Chaperones by Irina Shilenok, Ksenia Kobzeva, Vladislav Soldatov, Alexey Deykin, Olga Bushueva

“…<b>Background</b>: Recently identified Hero proteins, which possess chaperone-like functions, are promising candidates for research into atherosclerosis-related diseases, including ischemic stroke (IS). <b>Methods</b>: 2204 Russian subjects (917 IS patients and 1287 controls) were genotyped for fifteen common SNPs in Hero20 gene <i>C11orf58</i> using probe-based PCR and the MassArray-4 system. …”
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Osteopenic occult vertebral fracture is associated with poor oncological outcome in patients with hepatocellular carcinoma after hepatic resection by Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Masashi Tsunematsu, Michinori Matsumoto, Tomohiko Taniai, Yoshihiro Shirai, Shinji Onda, Ryoga Hamura, Toru Ikegami

“…Multivariate Cox proportional hazard models were conducted to assess disease‐free and overall survival adjusting for potential confounders. …”
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Modified life’s essential 8 mediate the correlation between dietary index for gut microbiota and sleep disorders by Juanjuan Fang, Zhenhua Wang, Jiangshui Yu, Yumin Ye, Apang Du, Markus W. Ferrari

“…We used restricted cubic spline (RCS) models to evaluate relationships between dose and response, and subgroup analyses to explore effect modifications. …”
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Big Data Analytics for Uncovering Voxel Connectivity Patterns in Attention Deficit Hyperactivity Disorder by Caraka RE, Supardi K, Gio PU, Isnaniawardhani V, Chen RC, Djatmiko B, Pardamean B

“…Dimensionality reduction and clustering techniques including Principal Component Analysis (PCA), KMeans, and MCLUST were used to explore underlying voxel patterns. …”
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Protective role of coenzyme Q10 against trihexyphenidyl-induced pulmonary toxicity in Wistar rats by Joseph Gbenga Omole, Lydia Oluwatoyin Ajayi, Itunuoluwa Rachael Ajewole, Teniola Osholonge, Oyedayo Phillips Akano, Ayodeji Folorunsho Ajayi

“…Coenzyme Q10 (CoQ10), a lipid-soluble antioxidant and mitochondrial cofactor, has been shown to protect against oxidative damage and apoptosis in various models of toxicity. However, its role in mitigating THP-induced pulmonary toxicity remains unexplored. …”
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Unveiling Theranostics: Nanocomplex-Assisted Photodynamic Eradication of Aggressive Cancer Cells and Modulation of Tumor-Associated Macrophages by Butkute A, Kazlauske E, Mlynska A, Peciukaityte E, Karabanovas V, Rotomskis R, Steponkiene S

“…Immunomodulatory effects were explored by exposing resident and recruited TAM models to a conditioned medium from PDT-treated CRC cells, followed by gene expression analysis.Results: Spectral characterization of the QDs-Ce6 nanocomplex demonstrated selective switching between diagnostic and therapeutic modes. …”
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A SORT1/EGFR molecular interplay as a prognostic biomarker in glioblastoma vasculogenic mimicry: implications in the transcriptional regulation of cancer stemness and drug resistan... by Marie-Eve Roy, Alain Zgheib, Nicoletta Eliopoulos, Borhane Annabi

“…This study questions whether the EGFR/SORT1 interplay impacts in vitro VM in human GBM-derived cell models. Methods In silico analysis was used to compare GBM to healthy brain tissue transcripts levels. cDNA arrays and RT-qPCR were performed to assess transcript levels in U87, U118, U138, and U251 GBM cells. …”
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Exploring the relationship between established HIV risk factors and depressive symptoms amongst young women without HIV in two sites in South Africa. by Zanenhlanhla Gumbi, Celia Mehou-Loko, Lindi Masson, Makhosazana Mdladla, Nokuthula Maphumulo, Jo-Ann Passmore, Sanele Mbeje, Linda Gail Bekker, Disebo Potloane, Heather Jaspan, Nina Radzey, Andrea Abrahams, Rushil Harryparsad, Pamela Mkhize, Hilton Humphries

“…The PHQ-9 scale was used to determine depressive symptomology, a socio-behavioural questionnaire was used to determine sexual behaviours, odds ratios and confidence intervals derived from logistic regression models were used to explore the associations between depressive symptomology and socio-behavioural factors associated with HIV acquisition.…”
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Excess mortality during and after the COVID-19 emergency in Japan: a two-stage interrupted time-series design by Shuhei Nomura, Masahiro Hashizume, Chris Fook Sheng Ng, Akifumi Eguchi, Ganan Devanathan, Paul LC Chua, Nasif Hossain

“…The study period extends beyond Japan ending the public health emergency.Methods Using national vital statistics data from 2015 to 2023, we employed a two-stage interrupted time series analysis to estimate excess mortality during the COVID-19 pandemic (2020–2023) compared with the prepandemic period (2015–2019). …”
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Nonlinear association between weekend sleep recovery (WSR) and insulin resistance: benefits in males and short weekday sleepers by Haidong Wang, Xiaohui Wei, Yudong Ba, Haiyan Liu, Yanhui Zhou, Weibo Wang, Lisheng Zheng

“…We used multivariable linear regression, stratified subgroup analyses (by sex, weekday sleep duration ≤7 vs >7 h, and different age groups), threshold effect modeling, and interaction analysis to assess associations. …”
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White-Matter Connectivity and General Movements in Infants with Perinatal Brain Injury by Ellen N. Sutter, Jose Guerrero-Gonzalez, Cameron P. Casey, Douglas C. Dean, Andrea de Abreu e Gouvea, Colleen Peyton, Ryan M. McAdams, Bernadette T. Gillick

“…Methods: Diffusion-weighted MRI data were analyzed in 17 infants, 12 with perinatal brain injury and 5 typically developing infants. …”
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Associations between Starting to Exercise in Later Life and Survival among Older Adults: a Nationwide, Community-based, Prospective Cohort Study in China by Haiyan Ruan, Ziqiong Wang, Kexin Wang, Muxin Zhang, Sen He

“…Accelerated failure time models were used to investigate the association between exercise duration and outcomes. …”
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Grade repetition and bullying victimization in adolescents: A global cross-sectional study of the Program for International Student Assessment (PISA) data from 2018. by Qiguo Lian, Chunyan Yu, Xiaowen Tu, Minglin Deng, Tongjie Wang, Qiru Su, Xiayun Zuo

“…This study aimed to investigate the global association of grade repetition with bullying victimization in a large-scale school-based cross-sectional study.<h4>Methods and findings</h4>We used the latest global data from the Program for International Student Assessment (PISA) 2018. …”
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Prognostic ability of the sTarT back screening tool for disability and pain intensity outcomes in older adults with low back pain seeking chiropractic care: a multi-national extern... by Yanyan Fu, Alan D. Jenks, Sidney M. Rubinstein, Katie de Luca, Iben Axen, Bart W. Koes, Alessandro Chiarotto

“…Therefore, our aim was to evaluate the ability of the SBT to predict three-, six-, and 12-month disability and pain outcomes in older adults (≥55 years) with a new episode of LBP consulting chiropractors in the Netherlands, Sweden, and Australia. Methods This was a secondary analysis of the Back Complaints in Older Adults – Chiropractic (BACE-C) cohort. …”
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Utilizing a modified-Postoperative Morbidity Survey for assessing morbidity after laparoscopic or robot-assisted radical prostatectomy: a retrospective observational study by Wenping Peng, Xiaolu Sun, Shuang Zhao, Huimin Hou, Jie Bao

“…Morbidity as defined by m-POMS was collected on postoperative day 1 (POD1), POD3, POD5 and POD8. Poisson regression models were employed to assess the correlation between positive m-POMS and postoperative LOS. …”
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Development of a mafedine lyophilizate for parenteral use by O. A. Terenteva, V. A. Vainshtein, V. V. Tikhonova, A. K. Whaley, M. A. Trofimov, V. A. Prikhodko, L. V. Shigarova

“…Residual solvents were determined by gas chromatography. Quantitative analysis of mafedine was performed by high-performance liquid chromatography. …”
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