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68861
Longitudinal history of mammographic breast density and breast cancer risk by familial risk, menopausal status, and initial mammographic density level in a high risk cohort: a nest...
Published 2024-11-01“…However, the contribution of longitudinal changes in mammographic density to breast cancer risk beyond initial mammographic density levels, considering familial breast cancer risk and menopausal status, remains uncertain but holds important clinical implications. Methods In a nested case–control study within the Sister Study (323 cases, 899 controls; 12,095 mammograms), a cohort enriched for family history of breast cancer, we examined case–control status in relation to the largest annual change in percent density and dense area using mammograms available spanning 5.4 years, on average, using multivariable logistic regression and to the rate of mammographic density change using linear mixed-effects models. …”
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68862
Plant-based diets and incident cardiovascular disease and all-cause mortality in African Americans: A cohort study.
Published 2022-01-01“…Non-Hispanic black Americans are an understudied group with high burden of CVD, yet studies of plant-based diets have been limited in this population.<h4>Methods and findings</h4>We conducted an analysis of prospectively collected data from a community-based cohort of African American adults (n = 3,635) in the Jackson Heart Study (JHS) aged 21-95 years, living in the Jackson, Mississippi, metropolitan area, US, who were followed from 2000 to 2018. …”
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68863
Personalized Support in Hereditary Breast and Ovarian Cancer After Genetic Counseling by the Chatbot-Based GENIE Mobile App: Proof-of-Concept Wizard of Oz Study
Published 2025-06-01“…The content is presented through predefined dialogs between the user and the mobile assistant, aiming to extend the benefits of genetic counseling beyond the initial session. MethodsA Wizard of Oz study was conducted to evaluate a functional prototype of GENIE. …”
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68864
Transforming nursing education: the power of educational leadership in optimizing time management and competency
Published 2025-07-01“…Data were analyzed using correlation and mediation analysis to assess the relationships between variables. …”
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68865
Temporal Trends of Maternal Mortality Due to Obstetric Hemorrhage in Chinese Mainland: Evidence from the Population-Based Surveillance Data Between 2000 and 2019
Published 2022-07-01“…Linear trends for changes in characteristics of maternal deaths were assessed using linear or logistic models with the year treated as a continuous variable. …”
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68866
Real-World Effectiveness of Nirmatrelvir/Ritonavir in Hospitalized Older Adults with Severe Omicron COVID-19: A Retrospective Cohort Study from China
Published 2025-06-01“…Kaplan-Meier analysis indicated that NMV/RTV improved 28-day survival in severe older COVID-19 patients. …”
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68867
High level of soluble tumor necrosis factor receptors is associated with lower residual diuresis volume in patients on hemodialysis: An exploratory study.
Published 2025-01-01“…This study aimed to explore the possible relationship between inflammatory parameters and residual diuresis volume in patients on hemodialysis.<h4>Methods</h4>Blood samples were collected from patients on hemodialysis for the analysis of soluble receptors: 1) tumor necrosis factor receptor 1 (sTNFR1), 2) tumor necrosis factor receptor 2 (sTNFR2), and 3) leptin. …”
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68868
Are there benefits of low doses of ACE inhibitors, MRAs, diuretics and statins in the treatment of heart failure?
Published 2021-07-01“…Risk factors were determined, and prognostic uni- and multi-variant Cox proportional hazards regression models were used. The cut-off values of quantitative risk factors were obtained by ROC analysis. …”
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68869
Bile acid metabolism in multiple sclerosis is perturbed and associated with the risk of confirmed disability worsening
Published 2025-04-01“…Differential expression analysis was used to study differences in BAs between pwMS and controls. …”
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68870
Orthodontic Treatment Stability Evaluation with Two Different Ligation Bracket Systems: An Ambispective Cohort Study
Published 2025-03-01“…All patients met the eligibility criteria and completed two years (T2) of retention with lower bonded retainers and upper removable Hawley retainers. Digital models and lateral cephalograms were taken pretreatment (T0), at debonding (T1), and at T2. …”
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68871
The magnitude of casual sex and associated factors among students at Debre Berhan University
Published 2024-12-01“…Once the data were imported into Epi-data version 4.6 and exported to SPSS version 20 for analysis, frequencies, percentages, and tables were generated. …”
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68872
Programmed cell death regulates hematopoietic cell homeostasis under radiation conditions
Published 2025-07-01“…However, it is uncertain whether different hematopoietic cells apply specific cell death pathways under irradiation exposure. Methods We investigated the role of different programmed cell death pathways in irradiation-induced hematopoietic cell injury. …”
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68873
Attitudes Toward AI Usage in Patient Health Care: Evidence From a Population Survey Vignette Experiment
Published 2025-05-01“…Our study offers novel insights into the relative importance of AI system characteristics for public attitudes and acceptance. MethodsWe conducted a factorial vignette experiment with a probability-based survey of 3030 participants from Germany’s general population. …”
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68874
The relationship between below average cognitive ability at age 5 years and the child’s experience of school at age 9
Published 2025-03-01“…Principal components analysis was used to produce a composite general cognitive ability score for each child. …”
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68875
Medicinal plants for the treatment and prevention of post-menopausal obesity: a review
Published 2025-05-01“…The review examines each plant’s taxonomic family, common name, bioactive compounds, and experimental evidence from cellular and animal models that illustrate potential anti-obesity mechanisms relevant to post-menopausal conditions.ResultsThe analysis reveals that phytoestrogens employ diverse mechanisms in mitigating obesity. …”
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68876
Front‐line treatment efficacy and clinical outcomes of elderly patients with multiple myeloma in a real‐world setting: A multicenter retrospective study in China
Published 2023-02-01“…Optimal treatment recommendation models for elderly patients with MM have not been developed especially there are quite few study in the real world. …”
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68877
Abstract 229: Recanalization Rate in Mechanical Thrombectomy in Patients With Elevated LDL‐C Levels
Published 2023-11-01“…Multivariable logistic regression models were fitted to determine the odds of the outcomes while adjusting for age, race, and gender. …”
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68878
Optimizing risk in action: Differences between fixated aim points and movement outcomes in throwing
Published 2025-01-01“…Here, we investigate sensorimotor behaviour under risk in throwing, across three experiments with 20 participants each. Methods Participants’ task was to throw balls on a target circle in a virtual reality (VR) setup, gaining 100 points for each hit. …”
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68879
Unveiling the impact of DNA-methylation age acceleration on mortality risk in diabetes and pre-diabetes: insights from the US NHANES program
Published 2025-05-01“…Cox proportional hazards regression models were employed to estimate the associations between DNAmAAs and all-cause, cardiovascular, and non-cardiovascular mortality. …”
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68880
“Miss having in-person classes” – university studying during COVID-19 pandemic
Published 2021-10-01“…Without suffi time for preparations, different models of distance education were applied. The aim was to ensure the continuity of teaching, to encourage the process of distance learning, and to enable their evaluation.Aim. …”
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