Role of air pollution exposure in the alteration of brain cortical structure: A Mendelian randomization study by Chaojuan Huang, Zimei Cheng, Xu Wu, Zhiwei Li, Mingxu Li, Xingliang Feng, Yuyang Zhang, Qian Zhao

“…Univariable MR (UVMR) was performed to assess the causality of air pollution on brain cortical structure using five MR methods. Multivariable MR (MVMR) was further conducted to strengthen the robustness of the identified relationships by adjusting for related pollutant phenotypes, household income, and unhealthy eating habits. …”
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Valuing health-related quality of life among the Indian population: a protocol for the Development of an EQ-5D Value set for India using an Extended design (DEVINE) Study by Atul Sharma, Manmeet Kaur, Shankar Prinja, Gaurav Jyani, Sitanshu Sekhar Kar, Mayur Trivedi, Binod Patro, Fredrick Purba, Star Pala, Swati Raman, Shalu Jain

“…Additionally, this study aspires to establish if the design of 10-time trade-off (TTO) blocks is enough to generate valid value sets.Methods and analysis A cross-sectional survey using the EuroQol Group’s Valuation Technology (EQ-VT) will be undertaken in a sample of 2700 respondents selected from six different states of India using a multistage stratified random sampling technique. …”
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Australian Particle Therapy Clinical Quality Registry (ASPIRE) protocol (TROG 21.12): a multicentre prospective study on patients with rare tumours, treated with radiation therapy by Hien Le, Scott Penfold, Sophie Jessop, Kelly Skelton, Peter Gorayski, Amber Murray, Daniel Hamilton, Adam Yeo, Eunji Hwang, Joshua Dass

“…During the MSAC 1638 application process, MSAC recognised the uncertainties inherent in the cost-utility modelling of PBT. To address these uncertainties, MSAC proposed the establishment of a national registry with the intention to gather evidence to validate the claim of PBT’s superior toxicity outcomes and cost-effectiveness compared with conventional photon radiation therapy.Methods and analysis The Australian Particle Therapy Clinical Quality Registry is a prospective, observational, longitudinal registry collecting national data on paediatric, adolescent young adult and adult patients with rare tumours receiving any form of radiation therapy for a defined group of diseases, specified by the MSAC 1638 Public Summary Document. …”
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Health implications of established and emerging stressors: design of the prospective New Jersey Population Health Cohort (NJHealth) Study by Dawne M Mouzon, Paul Duberstein, Joel C Cantor, William T Hu, Stephanie M Bergren, Mara Getz Sheftel, Steven B Cohen, Katherine B Morton, Dinesh Mendhe, Margaret Koller

“…The New Jersey Population Health Cohort (NJHealth) Study aims to characterise established and emerging stressors and delineate the pathways through which they influence health, especially among groups likely to experience chronic exposure to stressors including immigrants, people of colour, multigenerational families and low-income families.Methods and analysis A prospective cohort, the NJHealth Study is recruiting 8000 NJ residents aged 14 and older using probabilistic and purposive methods to include members of multigenerational families, marginalised racial/ethnic and low-income populations, and recent immigrant groups. …”
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Association of [¹⁸F]-FDG PET/CT-Derived Radiomic Features with Clinical Outcomes and Genomic Profiles in Patients with Chronic Lymphocytic Leukemia by Fabiana Esposito, Luigi Manco, Guglielmo Manenti, Livio Pupo, Andrea Nunzi, Roberta Laureana, Luca Guarnera, Massimiliano Marinoni, Elisa Buzzatti, Paola Elda Gigliotti, Andrea Micillo, Giovanni Scribano, Adriano Venditti, Massimiliano Postorino, Maria Ilaria Del Principe

“…This study examines the potential of PET/CT radiomics in predicting outcomes and genetic profiles in CLL patients. <b>Methods:</b> A retrospective analysis was conducted on 50 CLL patients treated at Policlinico Tor Vergata, Rome, and screened, at diagnosis, with [¹⁸F]-FDG PET/CT. …”
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Healing of lytic lesions and restoration of bone health in multiple myeloma through sclerostin inhibition by Hayley M. Sabol, Aric Anloague, Japneet Kaur, Cecile Bustamante-Gomez, Sharmin Khan, Bethany C. Paxton, Mattie R. Nester, Jillian Hackney, Marta Diaz-delCastillo, Daniel Mann, Jeffrey B. Stambough, C. Lowry Barnes, Elena Ambrogini, Alison Frontier, Frank H. Ebetino, Syed Naqvi, Frits van Rhee, Christopher P. Wardell, Matthew T. Drake, Intawat Nookaew, Carolina Schinke, Maurizio Zangari, Jesus Delgado-Calle

“…Methods To investigate these knowledge gaps, we used preclinical MM mouse models and patient-derived samples. …”
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The Potential of Hydrogeodesy to Address Water‐Related and Sustainability Challenges by Fernando Jaramillo, Saeid Aminjafari, Pascal Castellazzi, Ayan Fleischmann, Etienne Fluet‐Chouinard, Hossein Hashemi, Clara Hubinger, Hilary R. Martens, Fabrice Papa, Tilo Schöne, Angelica Tarpanelli, Vili Virkki, Lan Wang‐Erlandsson, Rodrigo Abarca‐del‐Rio, Adrian Borsa, Georgia Destouni, Giuliano Di Baldassarre, Michele‐Lee Moore, José Andrés Posada‐Marín, Shimon Wdowinski, Susanna Werth, George H. Allen, Donald Argus, Omid Elmi, Luciana Fenoglio, Frédéric Frappart, Xander Huggins, Zahra Kalantari, Simon Munier, Sebastián Palomino‐Ángel, Abigail Robinson, Kristian Rubiano, Gabriela Siles, Marc Simard, Chunqiao Song, Christopher Spence, Mohammad J. Tourian, Yoshihide Wada, Chao Wang, Jida Wang, Fangfang Yao, Wouter R. Berghuijs, Jean‐François Cretaux, James Famiglietti, Alice Fassoni‐Andrade, Jessica V. Fayne, Félix Girard, Matti Kummu, Kristine M. Larson, Martin Marañon, Daniel M. Moreira, Karina Nielsen, Tamlin Pavelsky, Francisco Pena, J. T. Reager, Maria Cristina Rulli, Juan F. Salazar

“…We find a growing body of literature relating to the advancements in hydrogeodetic methods, their accuracy and precision, and their inclusion in hydrological modeling, with a considerably smaller portion related to understanding hydrological processes, water management, and sustainability sciences. …”
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Gestational weight gain adequacy and intrapartum oxytocin and cesarean section use: Observational population‐based study in France by Melissa Amyx, Jennifer Zeitlin, Béatrice Blondel, Camille Le Ray

“…For the intrapartum oxytocin administration analysis, we included only women with spontaneous labor (n = 7352). …”
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Advancements in Herpes Zoster Diagnosis, Treatment, and Management: Systematic Review of Artificial Intelligence Applications by Dasheng Wu, Na Liu, Rui Ma, Peilong Wu

“…AI applications were analyzed across three domains: (1) diagnosis, where mobile deep neural networks, convolutional neural network ensemble models, and mixed-scale attention-based models have improved diagnostic accuracy and efficiency; (2) treatment, where machine learning models, such as deep autoencoders combined with functional magnetic resonance imaging, electroencephalography, and clinical data, have enhanced treatment outcome predictions; and (3) management, where AI has facilitated case identification, epidemiological research, health care burden assessment, and risk factor exploration for postherpetic neuralgia and other complications. …”
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Trends of respiratory viruses and factors associated with severe acute respiratory infection in patients presenting at a university hospital: a 6-year retrospective study across th... by Judith Carolina De Arcos-Jiménez, Judith Carolina De Arcos-Jiménez, Pedro Martinez-Ayala, Pedro Martinez-Ayala, Ernestina Quintero-Salgado, Rosendo Lopez-Romo, Jaime Briseno-Ramirez, Jaime Briseno-Ramirez

“…Viral trends were analyzed through interrupted time series (ITS) modeling, incorporating locally estimated scatterplot smoothing (LOESS) and raw positivity rates. …”
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Lonafarnib Protects Against Muscle Atrophy Induced by Dexamethasone by Sanghoon Bae, Van‐Hieu Mai, Seyoung Mun, Dalong Dong, Kyudong Han, Sunghyouk Park, Jung Keun Hyun

“…This study investigates the potential of lonafarnib, a farnesyltransferase inhibitor, to counteract DEX‐induced muscle atrophy by targeting key signalling pathways. Methods We utilized in vitro models with C2C12 myotubes treated with DEX and in vivo models with Caenorhabditis elegans and DEX‐treated Sprague–Dawley rats. …”
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Construction and characterization of chimeric FcγR T cells for universal T cell therapy by Juanjuan Zhao, Manling Chen, Xudong Li, Zhaoqi Chen, Wei Li, Rongqun Guo, Min Wang, Zhongxing Jiang, Yongping Song, Jianxiang Wang, Delong Liu

“…The functionality of CFR T cells was evaluated through degranulation assays, specific target lysis experiments, in vitro cytokine production analysis, and assessment of tumor xenograft destruction specificity in mouse models using different monoclonal antibodies (MoAbs). …”
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Yiqi Huayu Jiedu Decoction reduces colorectal cancer liver metastasis by promoting N1 neutrophil chemotaxis by Hua-Jian Zhou, Bai-Xiang Mu, Meng-Chao Wen, Qi Zhao, Yuanxiang Li, Wen-Xuan Zhao, Hong-Ye Yin, Shuai Ren, Jin-Yong Zhou, Jin-Yong Zhou, Min Chen

“…ObjectiveTo observe the inhibitory effect and potential mechanism of Yiqi Huayu Jiedu Decoction (YHJD) on liver metastasis of colorectal cancer (CRC).MethodsWe compared the changes of liver weight and liver index before and after YHJD treatment in CRC liver metastasis mouse models. …”
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Workplace-based dietary intervention study: Effects on body mass index and fat mass in metalworking industry workers by Luca DI GIAMPAOLO, Rossella MARTELLI, Daria ZICCARDI, Claudia GIURGOLA, Federica MARINO, Vittorio BARASSI, Paola BORRELLI, Laura FORCELLA, Maria Elisa MAIOLO, Rocco MANGIFESTA, Luca COPPETA, Francesca DI MECO

“…Anthropometric measures, including BMI and fat mass, were recorded at baseline and follow-up using bioimpedance analysis. Statistical analyses included paired t-tests and mixed linear models to assess changes over time. …”
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Perception of health and illness and quality of life after total thyroidectomy for differentiated thyroid carcinoma: the PERSAM study by Elena Groff, Beatrice Soccal, Fabiola Carrossa, Federica Vianello, Sara Talomo, Alessandra Feltrin, Giovanni Scarzello, Honoria Ocagli, Dario Gregori, Matteo Martinato

“…A descriptive statistics analysis and multiple linear regression models were performed to explore the relationship between some of the variables.ResultsSignificant associations emerged between the type of surgery and higher values on the PGWBI questionnaire (P = 0.022) and the score obtained in the ‘emotional representations’ dimension of the IPQ-R questionnaire (P = 0.028). …”
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Destripe Any Scale: Effective Stripe Removal Via Multiscale Decomposition Using the Luojia3-02 Stripe-Noise Dataset by Ru Chen, Mi Wang, Yingdong Pi, Ru Wang, Tao Peng, Fan Yang, Rongfan Dai

“…This noise manifests as linear, repetitive patterns that degrade image quality and impede the accurate data analysis. Existing destriping methods, including traditional statistical and frequency-based techniques, optimization-based approaches, and deep-learning models, each exhibit limitations in effectively addressing both small-scale and large-scale stripe noise, particularly in complex and heterogeneous imaging scenarios. …”
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The effect of bullying victimization on internet addiction: mediated by cyberbullying perpetration and moderated by social support by Yi Xie, Meng-Meng Zhang, Cong Wang, Jia Cai, Yu Wang, Yun-Fei Mu, Zhong-Yue Deng, Ai-Ping Deng, Hong-Jun Song, Lan Zhang, Jun Zhang, Yi Huang, Li Yin, Ting-Ting Jiang, Wen-Wu Shen, Ming-Li Li, Mao-Sheng Ran

“…General linear modeling (GLM), structural equation modeling (SEM), and interaction item analysis were conducted. …”
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Performance validation of deep-learning-based approach in stool examination by Kristal Dale Felimon Corpuz, Teera Kusolsuk, Benjamaporn Wongphan, Putza Chonsawat, Kaung Myat Naing, Siridech Boonsang, Veerayuth Kittichai, Chia-Kwung Fan, Santhad Chuwongin, Dorn Watthanakulpanich

“…Despite advancements in molecular methods with higher sensitivity and specificity, the Kato-Katz or formalin-ethyl acetate centrifugation technique (FECT) remains the gold standard and a routine diagnostic procedure suitable for its simplicity and cost-effectiveness. …”
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Real-world clinical burden of patients presenting with vaginitis symptoms in the United StatesAJOG MFM at a Glance by Justin Chen, Jenny Tse, Liucheng Shi, Mindy M. Cheng, Rebecca Lillis, Aimee M. Near

“…In a subset of patients with linkage to IQVIA Ambulatory EMR – US (AEMR), multivariable models were used to evaluate associations between insurance type, patient characteristics, diagnostic test(s) performed at presentation, and HCRU outcomes (subsequent vaginitis-related healthcare visits and ≥2 vaginitis treatment dates) over follow-up. …”
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Association between periodontitis and fracture-related infection in patients with severe open fractures of the upper and/or lower extremities by Sermsak Sukpanichyingyong, Surachai Sae-Jung, David A. Stubbs, Saksin Simsin, Thanasak Chengsuntisuk, Somkiat Luengpailin

“…Comprehensive data were collected for subsequent analysis. To explore the associations between periodontal status and the occurrence of FRI, statistical methods, including both univariate and multivariate regression models, were applied FRI, with a significance level set at 5%. …”
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