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68561
Effects of Electroacupuncture on Syt3 and GluA2 in Rats With Limb Spasms After Intracerebral Hemorrhage
Published 2025-03-01“…This study aims to explore the mechanism by which EA improves limb spasticity after ICH, providing scientific evidence for its clinical application. Methods ICH models were established using stereotaxic injection of autologous tail blood into the right striatum. …”
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68562
Comparison of heroin and fentanyl use in US nationally representative surveys
Published 2025-02-01“…We compare estimates of past-year heroin and IMF use and correlates of use in NSDUH and the Survey of Non-Medical Use of Prescription Drugs (NMURx) survey which employ an alternate sampling strategy. Methods We conducted a cross-sectional analysis of the 2022 NSDUH and NMURx. …”
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68563
Early net ultrafiltration thresholds and mortality in critically ill patients with septic acute kidney injury receiving continuous renal replacement therapy
Published 2025-12-01“…This study evaluated early NUF rates and survival in septic AKI.Methods A retrospective cohort of 219 adults with septic AKI requiring CRRT at a tertiary ICU was analyzed. …”
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68564
Novel non-resonant, low-frequency pulse–current circuit for energy-efficient, low-noise transcranial magnetic stimulation
Published 2025-06-01“…Each optimized triangular pulse–current waveform was modeled and simulated in MATLAB Simulink using these expressions. …”
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68565
Traumatic dental injuries in the first year of life and related risk factors in three regions of Brazil: a multicenter birth cohort study
Published 2025-01-01“…The aim of the present study was to estimate the incidence of TDI in the first year of life and explore risk factors in a birth cohort followed up in three major cities in different regions of Brazil. Methods A birth cohort study was conducted with children in the cities of Porto Alegre, Salvador, and Manaus. …”
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68566
Exploring the Multifactorial Predictors of Pain in Chronic Musculoskeletal Pain: A Regression-Based Study
Published 2025-04-01“…Stepwise regression analysis revealed that R-NPQ scores (20.7%), BMI (6.7%), education level (3.9%), and physical activity (2.6%) collectively explained 33.9% of the variance in pain intensity (adjusted R²=0.339). …”
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68567
Racial, Ethnic, and Language-Based Inequities in Inpatient Opioid Prescribing by Diagnosis from Internal Medicine Services, a Retrospective Cohort Study
Published 2023-01-01“…The study cohort included 61,831 patient hospitalizations. In adjusted models, we found that patients with limited English proficiency received significantly fewer opioids (66 MMEs, 95% CI: 52, 80) compared to English-speaking patients (101 MMEs, 95% CI: 91, 111). …”
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68568
Socioeconomic inequalities in infant mortality in Colombia: a nationwide cohort study during 10 years
Published 2025-08-01“…Key exposures included maternal educational level, health system enrolment scheme and area of residence. Cox regression models were used to estimate HRs, adjusting for relevant covariates. …”
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68569
Remote versus face-to-face home-based exercise programme in people with amyotrophic lateral sclerosis: protocol for a randomised clinical trial
Published 2022-05-01“…This study aims to evaluate the effects of remote versus face-to-face home-based exercise programmes on clinical outcomes and treatment adherence of people with ALS.Methods and analysis This is a single-blind randomised clinical trial protocol that will include 44 people with clinical diagnosis of ALS at any clinical stage and aged between 18 and 80 years. …”
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68570
Association of birth defects during the perinatal period with child mortality under 5 years
Published 2025-07-01“…ObjectiveTo calculate the impact of birth defects (BDs) diagnosed during the perinatal period on the mortality of children under 5 years of age.MethodsThis was a retrospective cohort analysis. From the monitoring system, we collected all hospital delivery, BD monitoring, and death information for children under 5 years in Hunan Province from 2017–2022. …”
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68571
COVID-19 in Pregnancy in Scotland (COPS): protocol for an observational study using linked Scottish national data
Published 2020-11-01“…We will determine associations between COVID-19 and adverse pregnancy, neonatal and maternal outcomes and the proportion of confirmed cases of SARS-CoV-2 infection in neonates associated with maternal COVID-19.Methods and analysis Prospective cohort study using national linked data sets. …”
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68572
Body Mass Index, Height, and Head and Neck Cancer Risk: The Japan Public Health Center-based Prospective Study
Published 2025-04-01“…This trend was also observed in quadratic models. Results were similar among never-smokers. …”
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68573
Studying an educational intervention and its impact on health-related quality of life and fasting blood glucose levels among patients with type 2 diabetes mellitus in rural China
Published 2025-07-01“…FBG levels and HRQoL (assessed via EQ-5D-3 L, EQ-VAS, and Paretian Classification of Health Change [PCHC]) were analyzed using difference-in-differences (DID) models and multinomial logistic regression. Results After adjusted for potential confounding factors, the intervention group exhibited a slower FBG increase compared to controls (DID: -0.65, 95% CI: -1.13 to -0.17), despite an overall upward trend in both groups. …”
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68574
A Systematic Review of Pneumonitis Following Treatment with Immune Checkpoint Inhibitors and Radiotherapy
Published 2025-04-01“…Identifying high-risk patients through predictive models, radiomics, and biomarkers may help tailor treatment strategies and minimize toxicity. …”
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68575
The intersection of stress, loneliness, and mental health attitudes in young multinational corporation employees
Published 2025-06-01“…However, existing research lacks a comprehensive analysis of how these factors interact and influence attitudes toward seeking psychological help. …”
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68576
The association between a body shape index and diabetic kidney disease in early-onset type 2 diabetes: evidence from a two-center study
Published 2025-06-01“…Multivariate logistic regression models were used to evaluate the association between ABSI and DKD, with additional analyses using restricted cubic splines (RCS) to explore dose-response patterns. …”
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68577
Exosome-transmitted HSPA9 facilitates bortezomib resistance by targeting TRIP13/USP1 signaling in multiple myeloma
Published 2025-03-01“…Our study aims to analyze the mechanism by which exosomes heat shock 70 kDa protein 9 (HSPA9) secreted by BTZ-resistant MM cells disseminate resistance to BTZ-sensitive MM cells. Methods The serum exosomes were identified by nanoparticle tracking analysis and transmission electron microscopy. …”
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68578
Influence of oromotor functions on motor development and feeding outcomes in children with cerebral palsy
Published 2025-12-01“…Regression models showed moderate positive correlations for age, weight, and height, with respective R2 values of 0.21, 0.23, and 0.28, indicating some influence on outcomes, but with much unexplained variability.Conclusions Gross motor function significantly influences feeding and orofacial motor function. …”
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68579
Features of the clinical course and treatment of anaphylaxis in children in the Ryazan region according to survey data
Published 2024-01-01“…Epidemiological studies on anaphylaxis in the Russian Federation are isolated, so the assessment of data from each region is relevant.Objective: to study the clinical features and medical care for anaphylaxis in children of the Ryazan region in real clinical practice.Materials and methods: A retrospective analysis of medical documentation was carried out in 300 children who had suffered an “acute allergic reaction” over the past 5 years, followed by a telephone survey of patients’ parents about the disease, and based on the clinical criteria for the diagnosis of anaphylaxis presented by the World Organization of Allergists (WAO) in 2020 and in the Federal Clinical Guidelines for the Diagnosis and Treatment of anaphylaxis, 57 patients were selected for anaphylactic shock of the Russian Federation in 2022, whose data were compared in a spreadsheet and analyzed using SPSS V24.0, including descriptive statistics.Results: It was revealed that the average age of first—time anaphylaxis is 3.5 years. …”
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68580
Postneonatal under-5 mortality in peri-urban and rural Eastern Uganda, 2005–2015
Published 2020-12-01“…Multilevel survival analysis models were used to identify factors associated with mortality.Results There were 43 043 postneonatal under-5 children contributing to 116 385 person years of observation, among whom 1737 died. …”
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