Risk stratification and clinical classification for postoperative neurological complications in post-tuberculosis kyphosis: a retrospective cohort study by Jianqiang Wang, Yong Hai, Haoshuang Geng, Zhangfu Li, Yuzeng Liu, Yangpu Zhang, Lijin Zhou

“…Two risk prediction models were developed accordingly. Synergistic interactions were identified between spinal cord MRI type and Rajasekaran classification, as well as between CRP and SCA. …”
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Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway by Jiawei Zhou, Anqi Cheng, Jianqiang Guo, Yafeng Liu, Xuan Li, Maoqian Chen, Dong Hu, Jing Wu

“…Furthermore, subcutaneous tumor xenograft models in nude mice were constructed to assess the effects of PRDX2 knockdown and the PRDX2 inhibitor Conoidin A on tumor growth in vivo. …”
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Informing equitable access to care: a cross-sectional study of travel burden to primary and rheumatology care for people with rheumatoid arthritis by Xiaoxiao Liu, Alka B Patel, Judy E Seidel, Dianne P. Mosher, John Hagens, Deborah A Marshall

“…The distance decay effect of travel time on health care utilizaton was modelled using a reverse cumulative probability approach. …”
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Potential of Sivelestat for Pulmonary Arterial Hypertension Treatment: Network Pharmacology-Based Target Identification and Mechanistic Exploration by Deng X, Qiu P, Li X, Hu Y, Que Q, Zhang K, Deng T, Liu Y

“…This study aims to investigate the potential of sivelestat as a treatment for PAH.Methods: Sivelestat’s effects on PAH were evaluated using hypoxia-induced rat models (10% O2, 4 weeks) and pulmonary arterial endothelial/smooth muscle cells (1% O2). …”
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The Influence of Guiding Concept on the Accuracy of Static Computer-Assisted Implant Surgery in Partially Edentulous Cases: An In Vitro Study by David Kasradze, Ričardas Kubilius

“…This study aimed to compare the accuracy of two guiding concepts of sCAIS in partially edentulous cases. <i>Materials and Methods</i>: Forty polyamide models of partially edentulous maxillae with seven implantation sites were fabricated. …”
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Risk factors for early suspected ventilator-associated pneumonia in severe thoracic blunt trauma patient: A French national cohort study. by Gary Duclos, Victor Vidal, Noemie Resseguier, Mathieu Boutonnet, Thomas Botrel, Gerard Audibert, Manon Séguret, Vincent Legros, Caroline Jeantrelle, Anh Dao Phan, Olivier Langeron, Elisabeth Gaertner, Jean-Luc Hanouz, Thomas Clavier, Véronique Ramonda, Fanny Bounes, Paër-Selim Abback, Mathieu Willig, Julien Pottecher, Marc Leone, for Traumabase® Group

“…The study included patients with severe blunt thoracic trauma requiring invasive mechanical ventilation. Data analysis focused on identifying independent risk factors for early suspected VAP (occurring within 48 hours to 5 days after ICU admission) using two models of logistic regression.…”
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Impact of fish oil supplementation on plasma levels of highly unsaturated fatty acid-containing lipid classes and molecular species in American football athletes by Veronica Anne Mullins, Justin M. Snider, Bryce Michael, Lydia Rose Porter, Roberta Diaz Brinton, Floyd H. Chilton

“…Docosahexaenoic acid (DHA), the primary omega-3 (n-3) highly unsaturated fatty acid (HUFA) in the brain, has shown neuroprotective effects in animal models after brain injury, but clinical research has shown mixed results. …”
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Associations of the C-reactive protein-albumin-lymphocyte index with all-cause and cardiovascular mortality among individuals with cardiovascular disease: evidence from the NHANES... by Dunzheng Han, Lanlan Wu, Haobin Zhou, Yuting Xue, Shangfei He, Zhuang Ma, Shuwen Su, Peixin Li, Shenrong Liu, Zheng Huang

“…Weighted multivariate Cox regression models and subgroup analyses were performed to assess the associations of the CALLY index with all-cause and cardiovascular mortality. …”
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Development and validation of a continuous fall risk score in community-dwelling older people: an ecological approach by Jorge Bravo, Hugo Rosado, Pablo Tomas-Carus, Cristina Carrasco, Nuno Batalha, Hugo Folgado, Catarina Pereira

“…Abstract Background Fall risk assessment in older people is of major importance for providing adequate preventive measures. Current predictive models are mainly focused on intrinsic risk factors and do not adjust for contextual exposure. …”
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From COPD to cancer: indacaterol’s unexpected role in combating NSCLC by Chenghao Liu, Jiaqi Huang, Pengjie Cai, Pengjie Cai, Min Jiang, Honglei Chen, Honglei Chen

“…Indacaterol significantly inhibited the viability of NSCLC cells in a concentration-dependent manner. Molecular modeling and CETSA experiments further indicated that indacaterol may bind to GLUT1 and affect GLUT1 expression. …”
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LncRNA LUCAT1 as a prognostic biomarker in cholangiocarcinoma through targeting miR-141-3p: clinical and functional insights by Yuxin An, Qing Chen, Shanshan Zhou, Chengcheng Ying, Guanbao Long, Zouxiao Hu, Jiangyang Sun, Niu Zhang

“…Diagnostic and prognostic significance was assessed through ROC curves, Kaplan-Meier survival analysis, and Cox regression models. The biological effects of LUCAT1 on cell proliferation and migration were examined using QBC939 and HuCCT1 cells with transfection assays. …”
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Precipitation, temperature, and child undernutrition: evidence from the Mali demographic and health surveys 2012–2013 and 2018 by Yusuke Kamiya, Takaaki Kishida, Mariam Tanou

“…This study, therefore, aimed to assess the effects of precipitation and temperature on child undernutrition in Mali, with a focus on climatic differences between the southern and northern regions. Methods We pooled the two most recent cross-sectional datasets from the Mali Demographic and Health Surveys (DHS) 2012–2013 and DHS 2018, integrating them with climatic variables at the DHS cluster level. …”
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Activation of angiopoietin-1 signaling with engineering mesenchymal stem cells promoted efficient angiogenesis in diabetic wound healing by Qiong Deng, Fangzhou Du, Shenzhen Pan, Yuchen Xia, Yuxin Zhu, Jingzhong Zhang, Chenglong Li, Shuang Yu

“…Subsequently, MSCANG1 was transplanted into streptozotocin (STZ)-induced diabetic wound models to evaluate therapeutic effects on angiogenesis and wound healing. …”
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Induced mitochondrial deficit by NDUFS3 transient silencing reduces RAB7 expression and causes lysosomal dysfunction in pancreatic cancer cells by Giulia Girolimetti, Sinforosa Gagliardi, Paola Cordella, Grazia Bramato, Riccardo Di Corato, Roberta Romano, Flora Guerra, Cecilia Bucci

“…Methods NDUFS3 and RAB7 downregulation was obtained by RNA interference (RNAi). …”
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Comparative association between NAFLD and MAFLD with cardiovascular events and mortality: Evidence from observational studies. by Taoli Fu, Jitao Ling, Huilei Zhao, Kaixin Lin, You Deng, Miao Zhang, Xinrui Qi, Peng Yu, Weichun Lin, Xiao Liu

“…Data extraction and study quality assessment were performed using the Newcastle-Ottawa Scale. Statistical analysis utilized random-effects models. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology.…”
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Safety study of leucoreduced allogeneic pooled freeze-dried platelet-rich plasma in healthy equine joints by Sarah Kooy, Jemma Constant, Robert Cole, Lindsey Boone

“…Local effects to the joint measured at different time points included heat, swelling, joint circumference, and response to passive flexion as well as synovial fluid analysis. Data was analyzed using linear mixed models with significance set at p &lt; 0.05.ResultsThere were no differences between groups for joint swelling (p = 0.40), joint circumference (p = 0.55), heat scores (p = 0.09), or passive flexion (p = 0.70) following intra-articular injections. …”
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Correlation between severity of knee joint osteoarthritis and alignment of patellofemoral and patellar height on radiographs by Zhenlei Yang, Mingjie Shen, Deshun Xie, Junzhe Zhang, Qingjun Wei, Yanjie Yin

“…Multiple linear regression models were used for the association between LPTA, SA, TT-TG, and severity of KOA after accounting for demographic variables. …”
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Predictive value of obesity-related indices for incident type 2 diabetes mellitus: a longitudinal study of the Fukushima Health Database 2015–2021 by Enbo Ma, Tetsuya Ohira, Maiko Fukasawa, Atsushi Shirafuji, Kenta Matsuzaki, Mitsuaki Hosoya, Seiji Yasumura, Michio Shimabukuro

“…Net reclassification improvements of models for CMI and LAP were similar to AIP, while those for Mets-IR, TyG, and VAI were significantly lower than AIP. …”
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Knowledge, Attitude, and Belief of Healthcare Professionals Toward Obesity Stigmatization by Lang H, Zhang X, Yan N, Du J, Jiang X

“…Multivariate logistic regression analysis revealed that having body mass index ≥ 24.0 kg/m² (OR = 0.537, 95% CI: 0.331– 0.873, P = 0.012) and nurse profession (OR = 0.546, 95% CI: 0.338– 0.883, P = 0.014) were independently associated with knowledge. …”
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Tibial tubercle transfer SurgeRy and physiothErapy Versus physIotherapy only for chronic paTellofemorAL paIn: study protocol for a randomiSed controllEd trial (REVITALISE) by Myrthe P. F. van de Ven, Martin Ophey, Victor van de Graaf, Sebastiaan A. W. van de Groes, Marijn Sinkeldam, Charlotte H. W. Wijers, Sander Koëter

“…Between-group differences will be analysed using multivariable linear regression analysis, while longitudinal differences will be assessed with linear mixed models for repeated measures. …”
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