Transitioning to residency: a qualitative study exploring residents’ perspectives on strategies for adapting to residency by Gerbrich Galema, Jasperina Brouwer, Tineke Bouwkamp-Timmer, Debbie A. D. C. Jaarsma, Götz J. K. G. Wietasch, Robbert R. J. Duvivier

“…This study explores residents’ strategies and experiences with organizational strategies to help them adapt to residency. Methods We conducted a template analysis of interview transcripts with 16 second-year residents from different hospital-based specialties in the Netherlands. …”
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Transition of clinical biomarker status from childhood into adolescence-A prospective study in children from eight European countries. by Anna Floegel, Paola Russo, Toomas Veidebaum, Michael Tornaritis, Dénes Molnár, Lauren Lissner, Stefaan De Henauw, Luis A Moreno, Wolfgang Ahrens, Manuela Marron, Claudia Börnhorst

“…Clinical blood biomarkers including glycated hemoglobin A1c (HbA1c), high-density lipoprotein cholesterol (HDL-cholesterol), triglycerides, C-reactive protein (CRP), interleukin 6, ferritin, leptin and insulin-like growth factor 1 (IGF-1) were repeatedly measured in 2007/2008 (age range: 3.0 to <10.0 years) and in 2013/2014. Latent transition analysis was used to estimate biomarker statuses and transition probabilities; determinants of biomarker status were estimated using mixed-effects models.…”
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Advances in vaccine-preventable diseases by Prof Helena Maltezou

“…Introduction: Vaccine-preventable diseases (VPDs) remain a significant cause of morbidity and mortality in children. Methods: Recent advances in VPDs were reviewed. Results: A modelling study showed that vaccinations accounted for 40% of the reduction of infant mortality during 1974-2024. …”
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Associations between symptom-based long COVID clusters and long-term quality of life, work and daily activities among individuals testing positive for SARS-CoV-2 at a national reta... by Manuela Di Fusco, Joseph C. Cappelleri, Alon Yehoshua, Kelly J. Thomas Craig, Mary B. Alvarez, Kristen E. Allen, Thomas M. Porter, Santiago M.C. Lopez, Laura Puzniak, Xiaowu Sun

“…Patient classes identified via latent class analysis (LCA) with long COVID-19 symptoms were simplified into clusters based on number of symptoms. …”
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Comparing the impact of Hydroxychloroquine based regimens and standard treatment on COVID-19 patient outcomes: A retrospective cohort study by Saja H. Almazrou, Ziyad S. Almalki, Abdullah S. Alanazi, Abdulhadi M. Alqahtani, Saleh M. Alghamd

“…The differences in ICU admission and mechanical ventilation were compared via logistic regression. All models were adjusted for age and gender variables. …”
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Patterns of comorbidities differentially affect long-term functional evolution and disease activity in patients with ‘difficult to treat’ rheumatoid arthritis by Prodromos Sidiropoulos, George Bertsias, Argyro Repa, Eleni Kalogiannaki, Antonios Bertsias, Nestor Avgoustidis, Sofia Pitsigavdaki, Irini D Flouri

“…Longitudinal clustering of functional status (modified Health Assessment Questionnaire (mHAQ)) and disease activity (Disease Activity Score-28 (DAS28)) were assessed using latent-class trajectory analysis. Multiple linear mixed models were used to examine the impact of comorbidities and their clusters on the long-term outcome.Results 251 out of 1264 patients (19.9%) were identified as D2T. …”
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Incidence of tuberculosis and its predictors among children on antiretroviral therapy in Amhara Region, Ethiopia: a multicentre institution-based retrospective follow-up study by Wubet Tazeb Wondie, Bruck Tesfaye Legesse, Gebrehiwot Berie Mekonnen, Fikadie Dagnew Baye

“…To identify TB predictors, Gompertz regression models, both bivariable and multivariable, were constructed. …”
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Determinants of health facility choice for delivery among women participating in group antenatal care in Machakos county, kenya: A cross-sectional survey by Jefferson Mwaisaka, Pooja Sripad, Melanie Olum, Patricia Owira, Samuel Mwaura, Rhoda Njeru, Daniel Muli, Faith Mutisya, Anne Hyre, Lisa Noguchi, Stephanie Suhowatsky

“…Most women (84.3%) delivered in the public sector. Regression analysis models revealed two significant predictors for delivery in the same G-ANC facility: proximity to the facility (adjusted AOR 4.13, 95% CI: 2.73–6.23, p < 0.001); and positive staff attitudes (adjusted AOR 4.68, 95% CI: 2.06–10.60, p < 0.001). …”
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Why they come, why they stay and why they leave: a survey to understand the drivers of recruitment, retention, and attrition of allied health clinicians in an Australian metropolit... by Abby M. Foster, Simone Munro, Janet Golder, Debra Mitchell

“…Challenges are shaped by population changes, emerging models of care, and educational limitations, and were exacerbated by COVID-19. …”
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Potential Mediating Role of Polygenic Hazard Score in the Association Between Neurofilament Light Chain and Default Mode Network Connectivity Across the Alzheimer's Disease Continu... by Parsa Saberian, Hamide Nasiri, Fatemeh Kaffashian, Parisa Nasiriansari, Fatemeh Nazari Nasab, Niusha Mehrvarz, Fatemeh Talebizadeh, Shayan Shakeri, Mahsa Mayeli

“…Partial correlation analyses and mediation models were performed, adjusting for age and gender. …”
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Comparison of outcomes with elranatamab and real world treatments in the UK for triple class exposed relapsed and refractory multiple myeloma by Carmen Tsang, Joseph E. O’Reilly, Lewis Carpenter, Charles Duffield, Filipa Tunaru, Jamie Wallis, Alycia Perkins, Thomas Price, Sam Wood, Karthik Ramasamy

“…Quantitative bias analysis was used to assess the robustness of effect estimates to unmeasured confounding. …”
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Prevalence of non-communicable diseases risk factors and their determinants: Results from STEPS survey 2019, Nepal. by Bihungum Bista, Meghnath Dhimal, Saroj Bhattarai, Tamanna Neupane, Yvonne Yiru Xu, Achyut Raj Pandey, Nick Townsend, Pradip Gyanwali, Anjani Kumar Jha

“…Data collection involved assessment of behavioral and biochemical risk factors. Complex survey analysis was completed in STATA 15, along with Poisson regression modelling to examine associations between covariates and risk factor prevalence.…”
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Role of antifibrotics in progressive pulmonary fibrosis associated to autoimmune diseases: multicenter study from NEREA registry by Maria Asuncion Nieto, Cristina Vadillo, Olga Sanchez Pernaute, Fredeswinda Romero-Bueno, María Jesús Rodriguez-Nieto, Rosalia Laporta, Hilda Godoy, Jesús Loarce, Juan Rigual, Leticia Leon, Lydia Abasolo

“…Cox multivariate regression models were run to examine the influence of antifibrotics and other covariates on, main outcome (results expressed as hazard ratio (HR) and [95%CI]). …”
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Risk factors for enteral nutrition-associated diarrhea in older patients with severe traumatic brain injury: a retrospective cohort study by Xiao-xiao Shi, Qiao-ling Zhang, Qian Li, Xiao-dan Lu, Li Fan, Jia-jiang Jiang, Xin-yi Tu, Qiu-si Hu, Li-zhu Wang

“…Demographic, clinical and nutritional data were collected for analysis. We utilize multiple logistic regression models to evaluate predictors of diarrhea. …”
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Hispanic Patients Undergoing Spinal Fusion for Neuromuscular Scoliosis Sustain Health Inequalities by Armando S. Martinez, David Momtaz, Travis Kotzur, Alexandra McLennan, Abdullah Ghali, Farhan Ahmad, Ebubechi Adindu, Alan C. Santiago-Rodriquez, Ali Seifi, Brian Smith

“…Our study aims to identify and describe those demographic factors associated with poor outcomes after spinal fusion with instrumentation in neuromuscular scoliosis to reduce health disparities and improve postoperative outcomes. Methods: A retrospective analysis was conducted using Healthcare Cost and Utilization Project data from 2016 to 2020, encompassing a random sample of 20% of procedures in the United States. …”
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Symptom variability in outpatients with COPD and validation of the Colombian COPD Symptom Variability Instrument (EPOC-CoVaSy) by Eidelman Antonio González-Mejía, Olga Constanza Uñate-Suárez, Carlos José Bula- Gutiérrez, Yojana Patricia Patiño-Jiménez

“…A MANOVA was performed using linear regression models to determine the correlations between the results of the diary and the instrument. …”
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Glymphatic System Dysfunction in Elderly Patients with Late-Onset Epilepsy and Comorbid Chronic Insomnia Revealed by Diffusion Tensor Imaging Along the Perivascular Space (DTI-ALPS... by Wang Y, Hu J, Zhang YY, Wang FY, Wu JC, Wang L

“…Simoa assays were performed to quantify Aβ 42 and Aβ 40 as plasma biomarkers of age-related neuropathology, and associations between the DTI-ALPS index and age, seizure frequency and duration, Sleep Quality Index (PSQI), Hamilton Rating Scale for Depression (HAMD), Hamilton Rating Scale for Anxiety (HAMA), Mini-Mental State Examination (MMSE), and Aβ 42:Aβ 40 ratio (Aβ 42/40) were assessed using Spearman correlation tests and multivariate logistic regression models.Results: Both DTI-ALPS index and Aβ 42/40 were significantly lower among LOE patients compared to HCs, and post-hoc analysis revealed even lower Aβ 42/40 and DTI-ALPS index values among LOE patients with comorbid chronic insomnia compared to HCs and LOE patients without chronic insomnia. …”
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Application of the multiphase optimisation strategy to develop, optimise and evaluate the effectiveness of a multicomponent initiative package to increase 2-to-5-year-old children’... by Rebecca K Golley, Shabnam Kashef, Dorota Zarnowiecki, Jennifer C Arguelles, David N Cox, Astrid AM Poelman, Maeva O Cochet-Broch

“…This study will use the multiphase optimisation strategy to develop, optimise and evaluate the effectiveness of a multicomponent initiative package to increase 2-to-5-year-old children’s vegetable intake in long day care centres.Methods and analysis The preparation phase will use existing literature and best practice guidelines to develop three initiatives aiming to: (1) increase vegetable provision at mealtimes, (2) deliver a vegetable-focused sensory curriculum and (3) use supportive mealtime practices encouraging children’s tasting of vegetables. …”
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Treatment decisions and surgery variables are predictors of better physical function after total hip and knee arthroplasty: a retrospective cohort study by Janis Nikkhah, Lukas Schöner, Carlos J. Marques, Christoph M. Pros, Reinhard Busse

“…This study investigated for patients undergoing THA or TKA: What is the association between patients’ characteristics, surgery variables, and treatment decisions with patient-reported outcomes (PROs) at discharge as well as at 12 M? Patients/methods We conducted a secondary, retrospective cohort analysis using longitudinal data from 6,144 THA and TKA patients who participated in the “PROMoting Quality Trial”. …”
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Cardiovascular Risk Factor Profiles and Disease in Black Compared to Other Africans with Chronic Kidney Disease by Hon-Chun Hsu, Chanel Robinson, Angela J. Woodiwiss, Gavin R. Norton, Patrick H. Dessein

“…Data were analysed in multivariable regression models. Results. Overall, black compared to other African CKD patients had less frequent carotid artery plaque (OR (95% CI) = 0.38 (0.16–0.91)) despite an increased cardiovascular risk factor burden. …”
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