Towards precision medicine strategies using plasma proteomic profiling for suspected gallbladder cancer: A pilot study by Ghada Nouairia, Martin Cornillet, Hannes Jansson, Annika Bergquist, Ernesto Sparrelid

“…Background & Aims: Currently, preoperative diagnostic methods that can distinguish cancer from benign disease of the gallbladder are insufficient, and several surgical resections can be avoided if the pathology is known prior to surgery. …”
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Features of “Inverted” Educational Resources for Distance Learning of Pupils by D. A. Barkhatova, A. L. Simonova, P. S. Lomasko, L. B. Khegay

“…Having already a certain baggage of knowledge and experience in the subject area being mastered, the student can begin the study by identifying deficiencies and possible difficulties, their reflection, and only then proceed to a more conscious formation of new knowledge and specific methods of action.Conclusion. In conclusion, the paper summarizes the features of “inverted” resources for distance learning of schoolchildren, provides further plans for the development of the project, and also identifies the possible areas to use the results.The materials of the article may be of interest to developers of digital learning resources, researchers of educational learning models, teachers wishing to use digital cognitive and mental learning technologies.…”
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Validation of the Nociception Level Index for the Detection of Nociception and Pain in Critically Ill Adults: Protocol for an Observational Study by Céline Gélinas, Shiva Shahiri T, Han Ting Wang, Maria Cecilia Gallani, Walid Oulehri, Denny Laporta, Philippe Richebé

“…Therefore, alternative pain assessment methods are urgently needed for this vulnerable patient population. …”
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Fractal Theory and Its Financial Applications for Improving the Quality of Professional Training at The Higher School of Economics by D. A. Vlasov, P. A. Karasev, A. V. Sinchukov

“…The article presents the didactic potential of modern fractal theory and its financial applications related to modeling and forecasting of financial performance. …”
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Impact of the Mother's Mental Health and Socioeconomic Status on Prenatal Attachment in a Population-Based Sample of Expectant Romanian Women by Brenda Cristiana Bernad, Dănuța Mitrache, Lavinia Hogea, Ana Pașcalău, Alin Gavreliuc, Marius Craina, Virgil Enătescu, Adrian-Bogdan Ciulpan, Adrian Lăcătușu, Diana Lungeanu, Venera Bucur, Elena Bernad

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Internal migration and depressive symptoms: Exploring selection and outcomes in a South African cohort by Carren Ginsburg, Tyler W. Myroniuk, Chantel F. Pheiffer, Bianca D. Moffett, Michael J. White

“…We employ logistic regression analysis to investigate selectivity of migrants in relation to depressive symptoms, and we fit generalized linear models to analyse depressive symptoms (CES-D scores) as a function of migration status and sociodemographic and health characteristics, accounting for temporal sequence. …”
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Endothelial Damage in Sepsis: The Interplay of Coagulopathy, Capillary Leak, and Vasoplegia—A Physiopathological Study by Gianni Turcato, Arian Zaboli, Lucia Filippi, Alessandro Cipriano, Paolo Ferretto, Michael Maggi, Fabrizio Lucente, Massimo Marchetti, Lorenzo Ghiadoni, Christian J. Wiedermann

“…Principal Component Analysis assessed the shared variance among variables. …”
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Proteomics uncovers ICAM2 (CD102) as a novel serum biomarker of proliferative lupus nephritis by Dan Gao, Dongwei Liu, Zhangsuo Liu, Zhengyong Li, Yifang Sun, Yixue Wang, Fengxun Liu, Shaokang Pan, Songwei Li, Zuishuang Guo, Jinghua Yang

“…The key networks associated with LN were screened out using Cytoscape software, followed by pathway enrichment analysis. The best candidate biomarkers were selected by machine learning models, further validated in a larger independent cohort. …”
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Post-Anesthesia Care Unit (PACU) readiness predictions using machine learning: a comparative study of algorithms by Shahnam Sedigh Maroufi, Maryam Soleimani Movahed, Azar Ejmalian, Maryam Sarkhosh, Ali Behmanesh

“…Unlike prior studies relying on statistical models or single-algorithm methods, this research assesses multiple ML models to predict discharge readiness, comparing them against staff evaluations and the Aldrete checklist. …”
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Estimating canopy fuels across Europe with satellite data and allometric equations by E. Kutchartt, E. Kutchartt, J. R. González-Olabarria, J. R. González-Olabarria, N. Aquilué, N. Aquilué, A. Trasobares, F. Pirotti, F. Pirotti

“…This study presents results regarding the estimation of two critical variables for modelling fire behaviour and fire danger: the canopy base height (CBH) and the canopy bulk density (CBD). …”
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Applying the VERACITY data framework: how do public health agencies score? by Mrs Rinette Badker, Mr. Benjamin Ash, Ms Naama Kipperman, Mr. Patrick Savage, Mr. Chris Pardee, Nita K Madhav

“…Introduction: The data framework, VERACITY (Verified, Encompassing, Representative, Accessible, Comprehensible, Interoperable, Timely, and Year-round), was developed to aid in the assessment of data consistency and reliability for use in epidemiological analysis and modeling. Here, we present a novel application of the VERACITY framework to reported data from several public health agencies to determine if the VERACITY framework meets its objectives. …”
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Sex hormone-binding globulin and sex-specific association between irritable bowel syndrome and type 2 diabetes: a prospective cohort study by Mengying Wang, Yinxi Tan, Huangda Guo, Hexiang Peng, Siyue Wang, Yi Zheng, Tianjiao Hou, Chenghua Gao, Wenyan Xian, Jie Huang, Tao Wu

“…Abstract Objective To investigate the sex-specific association between irritable bowel syndrome (IBS) and type 2 diabetes (T2D), and further explore whether sex-hormone binding globulin (SHBG) was an associated factor of the sex-specific association. Methods The study was a prospective analysis based on the UK biobank (UKB) data. …”
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Association Between Systemic Immune-Inflammatory Indices and Severity of Coronary Artery Lesions in Patients With Coronary Artery Disease in Different Glucose Metabolic States by Jin X, Liu Y, Jia W, Xu R, Guan X, Cui M, Zhang H, Wu H, Wei L, Qi X

“…Logistic regression and restricted cubic spline models were applied to estimate the relationship between SII and severity of coronary artery lesions in different glucose metabolic states with further adjustments for confounders.Results: Logistic regression analysis indicated a significant association between SII and coronary lesion severity (P < 0.05). …”
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Association between lipid profiles and platelet indices in middle-aged and older Chinese: a population-based cross-sectional study by Yanbo Li, Li Qin, Xiaoyong Li, Yixin Niu, Lina Chen, Xinyan Zhang, Hui Ran, Zhen Yang, Qing Su, Hongmei Zhang

“…Multiple linear regression models were then constructed to evaluate the impact of lipids on platelet indices, adjusting for these selected covariates. …”
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Association Between Serum Uric Acid to High-Density Lipoprotein Cholesterol Ratio and Pneumonia After Endovascular Treatment of Vertebrobasilar Artery Occlusion by Lan W, Yuan K, Xiao L, Qiu F, Sun W, Xu L, Cao H, Zhu W, Du M, Liu X

“…We used multivariable logistic regression models to assess the association between UHR and the risk of pneumonia after EVT and verified the findings in subgroup analysis.Results: Three hundred and seventy-eight patients were enrolled in this study, and 236 (62.4%) were diagnosed with pneumonia. …”
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Blood absolute lymphocyte count and trajectory are important in understanding severe COVID-19 by Catharine I. Paules, Jacqueline A. Nordwall, Kathryn Shaw-Saliba, Judith A. Aberg, Edward M. Gardner, Anna L. Goodman, N. Kumarasamy, Shikha Vasudeva, David M. Vock, Crystal M. North, Jens Lundgren, Neil R. Aggarwal, for the STRIVE Network and TICO Trial Study Group

“…Knowledge gaps remain regarding the relationship of ALC trajectory with clinical outcomes and factors associated with lymphopenia. Methods Our post hoc analysis of the Therapeutics for Inpatients with COVID-19 platform trial utilized proportional hazards models to assess relationships between Day (D) 0 lymphopenia (ALC < 0.9 cells/uL), D0 severe lymphopenia (ALC < 0.5 cells/uL) or lymphopenia trajectory between D0 and D5 with mortality and secondary infections, and with sustained recovery using Fine-Gray models. …”
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Aspartate aminotransferase-to-platelet ratio index as a novel predictor of early mortality in heat stroke patients: a multi-centre retrospective study by Min Wang, Yun Li, Yuan Cao, Meng-Meng Yang, Fu-Jing Liu, Jie Jiao, Sheng-Yuan Wang, Bin Song, Lu Wang, Yi-Qi Wu, Hong-Jun Kang

“…The independent association between APRI and outcomes was assessed using Cox proportional hazards models, with multivariable analyses controlling for confounding factors. …”
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Emergency department visits among rural and urban older adults: disparities in ambulatory and emergency care sensitive conditions by Cameron J. Gettel, Courtney Kitchen, Craig Rothenberg, Yuxiao Song, Ryan Koski-Vacirca, Katherine Schaffer, Alexander T. Janke, Nicholas M. Mohr, Margaret Greenwood-Ericksen, Arjun K. Venkatesh

“…We compared ED utilization for ambulatory care sensitive conditions (ACSCs) and emergency care sensitive conditions (ECSCs) among rural and urban Medicare beneficiaries. Methods We conducted a pooled cross-sectional analysis of 2016–2020 Medicare Current Beneficiary Survey data, assessing ED visitation rates for ACSCs and ECSCs. …”
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miR-21 and Pellino-1 Expression Profiling in Autoimmune Premature Ovarian Insufficiency by Xinran Li, Jiaxin Xie, Qingru Wang, Huihua Cai, Chuhai Xie, Xiafei Fu

“…Here, we conduct the target prediction of miR-21, identify the expression and correlation of miR-21 and its putative target Pellino-1 (Peli1), and confirm their relationship with clinical characteristics in autoimmune POI. Methods. Bioinformatic analysis was conducted to screen the miR-21 putative target gene. …”
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Diversity and seasonality of ectoparasite burden on two species of Madagascar fruit bat, Eidolon dupreanum and Rousettus madagascariensis by Angelo F. Andrianiaina, Santino Andry, Gwenddolen Kettenburg, Hafaliana Christian Ranaivoson, Vincent Lacoste, Philippe Dussart, Jean-Michel Heraud, Theresa M. Laverty, Sarah Guth, Katherine I. Young, Aristide Andrianarimisa, Cara E. Brook

“…The seasonal abundance of nycteribiid bat flies on both host bats was analyzed using generalized additive models, and the role of climate in driving this seasonality was assessed via cross-correlation analysis combined with generalized linear models. …”
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