Effectiveness of a Mobile Phone-Delivered Multiple Health Behavior Change Intervention (LIFE4YOUth) in Adolescents: Randomized Controlled Trial by Anna Seiterö, Pontus Henriksson, Kristin Thomas, Hanna Henriksson, Marie Löf, Marcus Bendtsen, Ulrika Müssener

“…ObjectiveThis study aimed to estimate the 2- and 4-month effectiveness of an mHealth intervention (LIFE4YOUth) targeting alcohol consumption, diet, physical activity, and smoking among Swedish high school students, compared with a waiting-list control condition. MethodsA 2-arm parallel group, single-blind randomized controlled trial (1:1) was conducted from September 2020 to June 2023. …”
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Psychological Well-Being in Adults Across the COVID-19 Pandemic: A Two-Year Longitudinal Study by Melanie Ehrler, Melanie Ehrler, Melanie Ehrler, Alexandra Vogt, Alexandra Vogt, Dominique Eichelberger, Matthias Greutmann, Cornelia F. Hagmann, Cornelia F. Hagmann, Oskar G. Jenni, Oskar G. Jenni, Oskar G. Jenni, Oliver Kretschmar, Oliver Kretschmar, Markus A. Landolt, Markus A. Landolt, Markus A. Landolt, Markus A. Landolt, Beatrice Latal, Beatrice Latal, Beatrice Latal, Beatrice Latal, Flavia M. Wehrle, Flavia M. Wehrle, Flavia M. Wehrle

“…Latent variable mixture modelling identified subgroups with distinct trajectories of well-being. …”
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Aurora kinase A promotes hepatic stellate cell activation and liver fibrosis through the Wnt/β-catenin pathway by Guanqi Dai, Guanqi Dai, Junhao Lin, Yuchuan Jiang, Yuchuan Jiang, Xinhui Liu, Peng Chen, Yixiao Zhang, Zhenghui Song, Xuefen Zhuang, Jinge Cong, Yingchun Li, Xuanjia Hong, Yun Liu, Dong Xiao, Dong Xiao, Aimin Li, Yue Luo

“…This study aimed to investigate the impact and underlying mechanism of AURKA on liver fibrosis and to assess the therapeutic potential of MLN8237, a small-molecule AURKA inhibitor, in preventing liver fibrosis in mice.MethodsThe research used bioinformatics analysis and immunohistochemistry staining on fibrotic liver tissues from human and mouse models to assess AURKA expression. …”
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Allergen-specific circulating CLA+ memory T cells stratify IL-22 response in atopic dermatitis skin by Irene García-Jiménez, Irene García-Jiménez, Lídia Sans-de San Nicolàs, Sandra Díez-Ribas, Laia Curto-Barredo, Marta Bertolín-Colilla, Ana Vivancos-Melenchón, Ignasi Figueras-Nart, Montserrat Bonfill-Ortí, Anna Ryzhkova, Marta Ferran, Tali Czarnowicki, Ramon M. Pujol, Luis F. Santamaria-Babí

“…BackgroundCurrent understanding of IL-22 in atopic dermatitis (AD) mostly relies on animal models, intracellular staining of polyclonally activated peripheral lymphocytes, and biological therapies.MethodsWe evaluated the IL-22 response to house dust mite (HDM) extract in 58 patients with moderate-to-severe AD using a coculture system made of circulating memory cutaneous lymphocyte associated antigen (CLA)+/− T cells with autologous lesional epidermal cells. …”
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The state of the science of interprofessional collaborative practice: A scoping review of the patient health-related outcomes based literature published between 2010 and 2018. by May Nawal Lutfiyya, Linda Feng Chang, Cynthia McGrath, Clark Dana, Martin S Lipsky

“…Eight outcome categories emerged from a content analysis of the findings of the reviewed studies.<h4>Conclusions</h4>The results suggest a need for more research on the measurable impact of interprofessional collaborative practice and/or care on patient health-related outcomes to further document its benefits and to explore the models, systems and nature of collaborations that best improve population health, increase patient satisfaction, and reduce cost of care.…”
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Rationale and design of healthy at home for COPD: an integrated remote patient monitoring and virtual pulmonary rehabilitation pilot study by Laurel O’Connor, Stephanie Behar, Seanan Tarrant, Pamela Stamegna, Caitlin Pretz, Biqi Wang, Brandon Savage, Thomas Thomas Scornavacca, Jeanne Shirshac, Tracey Wilkie, Michael Hyder, Adrian Zai, Shaun Toomey, Marie Mullen, Kimberly Fisher, Emil Tigas, Steven Wong, David D. McManus, Eric Alper, Peter K. Lindenauer, Eric Dickson, John Broach, Vik Kheterpal, Apurv Soni

“…This paper details the recruitment, methods, and analysis plan for the study, which is recruiting 100 participants in its pilot phase. …”
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Use of real-world data to study health services utilisation and comorbidities in long-term breast cancer survivors (the SURBCAN study): study protocol for a longitudinal population... by Xavier Castells, Beatriz Poblador-Plou, Alexandra Prados-Torres, Maria Sala, Javier Gorricho, Anna Jansana, Isabel Del Cura, Teresa Sanz Cuesta, A Gimeno Miguel, Manuela Lanzuela, Berta Ibañez, Ibai Tamayo, Conchi Moreno-Iribas, María Padilla-Ruiz, Maximino Redondo, Mercè Comas, Laia Domingo, Antonio Díaz-Holgado, Francisco Javier Salamanca, Mercè Abizanda, Talita Duarte, Javier Louro, María del Carmen Martínez, Cristóbal Molina, Guillermo Pérez, Ana María Muñoz, Óscar Toldos, Javier Baquedano, Rossana Burgui

“…The aim of the SURBCAN study is to describe comorbidity, healthcare services use and adherence to preventive recommendations in long-term breast cancer survivors and to compare them with those in women without this diagnosis in order to improve and adapt the care response to this group of survivors.Methods and analysis Population-based retrospective cohort study using real-world data from cancer registries and linked electronic medical records in five Spanish regions. …”
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高敏感特質中高齡學習者面對數位學習壓力及疫情焦慮之學習滿意度與後疫情調適：復原力之中介效果 Learning Satisfaction and Post-Pandemic Adaptation in Highly Sensitive Middle-aged and Elderly Learners in the Face of Digital Learni... by 王雅鈴 Ya-Ling Wang, 張伶瑜 Lin-Yu Chang, 羅淇文 Chi-Wen Luo, 林郁文 Yu-Wen Lin

“…The collected data were analyzed using structural equation modeling (SEM) with the Bootstrap statistical method for mediation analysis. …”
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Autophagy and exosome dynamics in Radiation-Induced pulmonary fibrosis: the critical role of TRIB3 by Na Li, Wenyue Zhao, Jiale Li, Dengfeng Zhang, Kejun Li, Mengmeng Yang, Xinran Lu, Liqing Du, Chang Xu, Qiang Liu

“…This study aimed to elucidate the role of TRIB3 in RIPF progression. Methods We conducted RNA-sequencing of rat RIPF lung tissue to analyze the transcriptomic profile and determine gene expression changes in murine with RIPF. …”
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A nationwide retrospective cohort study of the association between acupuncture exposure and clinical outcomes of idiopathic Parkinson’s disease using health insurance claim data in... by Ye-Chae Hwang, Jungkuk Lee, Dongwoo Kang, Han-Gyul Lee, Seungwon Kwon, Seung-Yeon Cho, Seong-Uk Park, Woo-Sang Jung, Sang-Kwan Moon, Jung-Mi Park, Jungtae Leem, Chang-Nam Ko

“…Propensity score matching (PSM) was applied, and Cox proportional hazards models were used for survival analysis. During a 6-year follow-up, hazard ratios (HRs) were estimated for overall and cause-specific mortality, emergency room visits, fractures, and the first deep brain stimulation (DBS) procedure, using the non-acupuncture group as the reference. …”
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Same-visit hepatitis C testing and treatment to accelerate cure among people who inject drugs (the QuickStart Study): a cluster randomised cross-over trial protocol by Andrew B Forbes, Jessica Kasza, Thomas L Snelling, David Anderson, Joseph S Doyle, Peter Higgs, Margaret E Hellard, Nick Scott, Alisa E Pedrana, Alexander J Thompson, Jessica Howell, Timothy Spelman, Beatriz Camesella, Imogen Elsum, Kico Chan, Mark A Stoové, Paul M Dietze, Mellissa Bryant, Katherine Heath, Rodney Guzman, Caitlin Douglass, Amanda Wade, Kate Allardice, Sally Von Bibra, Jacqui Richmond, Nada Andric, Rachel Sacks‐Davis

“…Increasing DAA uptake by PWID is important for interrupting transmission and reducing incidence, as well as reducing morbidity and mortality and improving quality of life of PWID and meeting Australia’s hepatitis C elimination targets.Methods and analysis A cluster randomised cross-over trial will be conducted with three intervention arms and a control arm. …”
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Cerebrospinal fluid pressure dynamics as a biomechanical marker for quantification of spinal cord compression: Conceptual framework and systematic review of clinical trials by Najmeh Kheram, Madeleine A. Bessen, Claire F. Jones, Benjamin M. Davies, Mark Kotter, Mazda Farshad, Markus Hupp, Daniel Nanz, Patrick Freund, Martin Schubert, Vartan Kurtcuoglu, Armin Curt, Carl M. Zipser

“…Research question: Evidence for safety and feasibility of CSFP dynamics in clinical trials as well as interrelations with neuroimaging and intraspinal pressure, and relation to preclinical CSFP models. Material and methods: Systematic review. This review followed PRISMA guidelines, risk of bias assessment with ROBINS-I tool, PROSPERO registration (CRD42024545629). …”
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The invisible threat: A 30-year review of air pollution's impact on diarrhoea from the global burden of disease study 2021 by Changhao Zhang, Kaiqi Yang, Yang Yu, Haoxi Liu, Yijun Chen, Jiaxuan Zuo, Minyue Yin, Yuchen Ding, Jinlong Chen, Xiujing Sun, Shutian Zhang

“…In addition, Auto-Regressive Integrated Moving Average (ARIMA) and Ensemble Smoothing (ES) models were used to predict the epidemic trends of diarrhoea from 2022 to 2046, and frontier analysis was conducted to explore the potential reduction in the burden of diarrhoea in different regions. …”
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Regulatory Impacts of the Three Gorges Dam on Long-Term Terrestrial Water Storage Anomalies in the Three Gorges Reservoir Area: Insights from GRACE and Multi-Source Data by Yu Zhang, Yi Zhang, Sulan Liu, Xiaohui Wu, Yubin Liu, Yulong Zhong, Yunlong Wu

“…This study examines long-term terrestrial water storage anomalies (TWSA) in the Three Gorges Reservoir Area (TGRA) over two decades, from 2003 to 2023. The analysis utilizes data from the Gravity Recovery and Climate Experiment (GRACE) and its successor mission (GRACE-FO), complemented by Global Land Data Assimilation System (GLDAS) models and ECMWF Reanalysis v5 (ERA5) datasets. …”
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Greater pain and functional impairment in chronic erosive hand osteoarthritis compared to treated rheumatoid arthritis: A comparative study by S. Berkani, S. Tuffet, A. Rousseau, N. Rincheval, E. Maheu, B. Combes, A. Saraux, B. Fautrel, L. Gossec, F. Berenbaum, J. Sellam, A. Courties

“…Objectives: To compare the burden of established chronic rheumatoid arthritis (RA) and erosive hand osteoarthritis (EHOA), in terms of pain, functional impairment, comorbidities, and cardiometabolic diseases (CMD). Methods: This study included EHOA patients from the inclusion visit of the DIGICOD cohort and RA patients from the 10th year visit of the ESPOIR cohort. …”
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Exploring the correlations of lung ultrasound with delirium and other clinical outcomes in older patients with respiratory failure admitted in acute geriatric units (ECO-AGE): prot... by Andrea Ticinesi, Fulvio Lauretani, Antonio Nouvenne, Tiziana Meschi, Giuseppe Bellelli, Andrea Ungar, Marcello Maggio, Simone Scarlata, Raffaele Antonelli Incalzi, Fabio Monzani, Carmine Siniscalchi, Chukwuma Okoye, Alberto Finazzi, Adriana Antonella Bruni, Daniela Guarino, Nicoletta Cerundolo, Irene Zucchini, Monica Torrini, Michele Cerasuolo, Maria Rosaria Rizzo, Sonia Zotti, Marco Lunian, Lorenzo Maccioni, Silvia Fabbri della Faggiola, Marco Capacci, Maria Giovanna Bianco, Guglielmo Guarona, Panaiotis Finamore, Emma Esposito, Lavinia Vitali, Tessa Mazzarone, Martina Salvati

“…LUS may therefore help identify individuals at risk of delirium, but the association between LUS abnormalities and delirium remains unexplored.Methods and analysis This study is a prospective, observational, multicentre study, with the main objective of assessing the correlation between LUS abnormalities and incident delirium during hospitalisation (primary outcome). …”
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Safety of mycophenolate mofetil in systemic lupus erythematosus maintenance therapy: insights from the LUNA registry in a nationwide prospective cohort study by Ken-ei Sada, Shuhei Yoshida, Kenji Saito, Yuya Fujita, Eisuke Inoue, Kiyoshi Migita, Naoki Matsuoka, Hiroshi Kajiyama, Ryusuke Yoshimi, Kunihiro Ichinose, Yoshia Miyawaki, Shigeru Ohno, Nobuyuki Yajima, Yasuhiro Shimojima, Shuzo Sato, Michio Fujiwara, Keisuke Nishimura, Takashi Kida, Yuya Sumichika, Haruki Matsumoto, Jumpei Temmoku, Tomoyuki Asano, Shotaro Ogawa, Jumpei Fukita, Yusuke Matsuo, Takahisa Onishi

“…Statistical analyses employed marginal structural models with stabilised inverse probability of treatment weighting to adjust for confounders.Results The analysis included 1004 patients; the incidence of severe infections was 6.5% in the MMF group and 7.5% in the non-MMF group, with no significant difference (OR 0.69, 95% CI 0.34 to 1.39). …”
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Gut health-promoting foods intake in Argentine adults: The impact of knowledge, socio-demographic factors, and clinical-nutritional health by Georgina Noel Marchiori, Mayra Ainelén Loyola, Clara Marián Levy Sánchez, María Daniela Defagó, María Georgina Oberto

“…An online questionnaire was used to collect socio-demographic, clinical-nutrition and dietary data, as well as information about population's knowledge. Logistic regression models were used for analysis. Results: Fermented foods and probiotic-rich yogurts were consumed occasionally, while prebiotic food intake was more frequent. …”
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The mediating role of physical activity avoidance in the association between weight stigma and physical activity by Po-Ching Huang, Hung-Ching Wu, Ji-Kang Chen, Xavier C.C. Fung, Nadia Bevan, Daniel Kwasi Ahorsu, Mark D. Griffiths, Jung-Sheng Chen, Kuo-Hsin Lee, Amir H. Pakpour, Chung-Ying Lin

“…Measurement invariance of the TAPAS was tested to ensure that the combining of data from Hong Kong and Taiwan participants was appropriate for further analysis. Results: Structural equation modeling showed that weight-related self-stigma was significantly associated with PA avoidance (standardized coefficient [β] = 0.67, p < 0.01), and negatively associated with PA (β = −0.14, p < 0.01). …”
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Influence of different treatment modalities on the sexual function of breast cancer survivors: An observational ambispective study by Natalia Camejo Martinez, Cecilia Castillo Leska, María Rosina Servetto Martinez, Miriam Gianina Muñoz Arce, Joaquín Manzanares Cuevas, Dahiana Lourdes Amarillo Hernández, María Gabriela Guerrina Valeta, Guadalupe Rocío Herrera Álvarez, María Carolina Dörner Cabrera, Gabriel David Krygier Waltier

“…Patients completed the Female Sexual Function Index questionnaire, and the data were analyzed using simple and multiple binary logistic models to assess the relationship between treatment modalities and sexual dysfunction. …”
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