Association of cardiovascular health with reproductive lifespan and pregnancy loss: insights from NHANES 2005–2018 by Yang Yan, Jiajia Chen, Jinlong Qin, Min Yu, Meirong Du, Meirong Du

“…We conducted multivariable linear regression models and zero-inflated negative binomial regression models to investigate the prospective association of CVH with reproductive lifespan and pregnancy loss while accounting for various potential confounders. …”
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Removing seasonal confectionery from prominent store locations and purchasing behaviour within a major UK supermarket: Evaluation of a nonrandomised controlled intervention study. by Carmen Piernas, Georgina Harmer, Susan A Jebb

“…Here, we evaluated a grocery store intervention to remove seasonal confectionery from prominent locations within a major UK supermarket.<h4>Methods and findings</h4>A nonrandomised controlled intervention study with interrupted time series (ITS) analysis was used. …”
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Diagnostic Efficacy of ¹²³Iodo-Metaiodobenzylguanidine SPECT/CT in Cardiac vs. Neurological Diseases: A Comparative Study of Arrhythmogenic Right Ventricular Cardiomyopa... by Johannes M. Hagen, Maximilian Scheifele, Mathias J. Zacherl, Sabrina Katzdobler, Alexander Bernhardt, Matthias Brendel, Johannes Levin, Günter U. Höglinger, Sebastian Clauß, Stefan Kääb, Andrei Todica, Guido Boening, Maximilian Fischer

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Antenatal group-based psychoeducation to improve postpartum depression literacy in primary health care institutions in Ethiopia: a cluster randomized controlled trial by Marta Tessema, Muluemebet Abera, Zewdie Birhanu

“…General linear models and mixed-effect models assessed intervention effects and outcome variable predictors, respectively.ResultsThe overall response rate was 92.9%. …”
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Comparison of AI and resident doctors in diagnosing and managing acute respiratory cases: a retrospective study by Abdurrahmaan Manga, Saher Sultan, Ammarah Yasmeen, Fasihul Khan

“…This study aimed to evaluate how the diagnostic and management decisions made by resident doctors and ChatGPT compared to a consultant-defined gold standard within a tertiary hospital setting. Methods: A retrospective analysis was conducted on 45 patients admitted to the respiratory admissions unit. …”
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Metal mixtures exposure with risk of elevated serum neurofilament light chain concentrations in U.S. general adults, NHANES 2013–2014 by Yan Wang, Keyi Zhang, Hao Li, Si Liu, Linyao Ying, Lu Xiang, Na Liang, Liangkai Chen, Lin Xiao, Gang Luo

“…Cd (69.6 %) and Pb (8.9 %) were the primary drivers of the association between metal mixtures exposure and sNfL concentrations. Analysis of WQS and BKMR models showed a positive association between metal mixtures exposure and sNfL concentrations, especially in older, and male participants. …”
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Impact of prenatal triclosan exposure on ADHD-like symptoms in school-aged children by Jingjing LI, Xiaomeng CHENG, Yan ZHANG, Luanluan LI, Xiaodan YU, Ying TIAN, Yu GAO

“…Nevertheless, relevant research in China remains limited.ObjectiveTo investigate the impact of early pregnancy TCS exposure on ADHD-like symptoms in 7-year-old children.MethodsThis study was based on the Shanghai Birth Cohort (SBC) and included 662 mother-child pairs. …”
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Circulating miRNA-486 as a novel diagnostic biomarker for right ventricular remodeling by Huiling Cai, Huiling Cai, Cheng Yu, Xiuchuan Li, Xuenan Wang, Xuenan Wang, Yongjian Yang, Yongjian Yang, Yongjian Yang, Cong Lan, Cong Lan

“…This study systematically screened and identified candidate serum miRNAs as potential diagnostic biomarkers for RV remodeling in PH patients.MethodsPulmonary artery banding (PAB) was performed in Sprague-Dawley (SD) rats and RV modeling was measured by echocardiographic and histological analyses 4 weeks after surgery. …”
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PLZF-expressing CD4+ T cells promote tissue-resident memory T cells in breaking immune tolerance in allergic asthma via IL-15/IL-15Rα signaling by Meng Zhang, Sheng-ce Tao, Na Li, Jingjing Feng, Tianyun Shi, Yunxia Yu, Xiaoting Ren, Jiafeng Sha, Zhoufang Mei, Zhijun Jie

“…Therefore, in the current study, we explore the role of CD4+ TRM cells in asthmatic immune tolerance and as well as the regulatory role of PLZF in this process. Methods To elucidate the role of CD4+ TRM cells in immune tolerance, asthma memory mouse models were treated with the immunomodulator FTY720. …”
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Association between serum and red blood cell folate concentrations and urinary phthalate metabolite concentrations in US adults: evidence from a large population-based study by Xiaojing Huang, Xiaojing Huang, Huan Zhang, Huan Zhang, Yaoyu Luo, Chenhui Yang, Jue Huang, Jue Huang, Ting Zhou, Ting Zhou, Junfeng Qi, Junlin Li, Shuzhen Zhu, Yaqin Zhang, Ling Zhang, Ling Zhang, Xiaojie Sun, Xiaojie Sun

“…We aimed to explore the relationship between blood folate biomarker concentrations and urine phthalate metabolites.MethodsBased on data from the National Health and Nutrition Examination Survey spanning 2005 to 2016, 8,218 participants with measurements of folate biomarkers in blood and phthalates exposure in urine were included. …”
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Association between novel Immune-Inflammatory markers and hypertension patients with coronary heart disease: A Cross-Sectional study based on NHANES (2005–2016) by Ruiyuan Li, Aili Atawula, Haonan Li, Moran Li, Jiamin Tang, Jie Liu, Jieying Shi, Jingjing Hou, Feng Hai, Yifan Zhao, Lipeng Guo

“…All the three models had good discrimination power. Decision curve analysis indicated that all three nomogram models are effective in clinical practice. …”
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Cost evaluation of acute ischemic stroke in Latin America: a multicentric studyResearch in context by Luiza Borba Dittrich, Ana Paula Beck da Silva Etges, Joana Siqueira de Souza, Miriam Allein Zago Marcolino, Eva Rocha, Pablo Amaya, Miguel A. Barboza, Andrés Gaye Saavedra, Gonzalo Pérez Hornos, Carlos Abanto, Ana Lucía Castillo-Soto, Natalia Llanos-Leyton, Virginia Pujol Lereis, María Soledad Rodriguez Pérez, Matías Alet, Victor Navia, Solange Lopez, Antonio Arauz, Fabiola Serrano, Bruna Chwal, Leonardo Augusto Carbonera, Raul Gomes Nogueira, Gustavo Saposnik, Carisi Anne Polanczyk, Sheila Cristina Ouriques Martins, Ana Cláudia de Souza

“…The findings aim to lay a solid foundation for adopting value-based healthcare (VBHC) strategies in the region. Methods: The study is an observational, multicenter, international analysis of direct costs and outcomes for patients hospitalised with acute ischemic stroke from December 2021 to December 2022. …”
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The pattern of state organization in the new constitution of Lithuania: A third way between the presidential and parliamentary systems? by Andreas Hollstein

“…The author focuses the analysis upon the following question: does the Constitution of the Republic of Lithuania of 1992 establish a third way between the parliamentary and presidential democracy? …”
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Independent and interactive associations of inflammation, vascular homeostasis markers, and childhood trauma with suicide attempt history by Ainoa García-Fernández, Aiste Lengvenyte, Elia Gourguechon-Buot, Emilie Olié, Fabrice Cognasse, Pilar A. Sáiz, Philippe Courtet

“…This study examined the relationships between immune-inflammatory and vascular homeostasis-related markers and their interaction with childhood trauma in relation to a history of suicide attempts in individuals with depression. Methods A total of 328 patients with major depression were recruited: 166 with a history of suicide attempts and 162 without. …”
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Preclinical and clinical evaluation of intratumoral injection of an IL-12 expressing SKV-012 oncolytic virus for advanced solid tumors by Jing Jin, Zheng Jiang, Jun Liu, Hui Yang, Long Xu, Weiwei Zhang, Xingchen Peng, Nian Yang, Zongliang Zhang, Liangxue Zhou, Aiping Tong, Huaqing Lu, Yongdong Chen, Liyuan Jin

“…Background SKV-012 is a novel engineered oncolytic virus (containing the viral neurovirulence ICP34.5 gene transcribed by the Survivin promoter with an upstream genetic component of interleukin-12 (IL-12) driven by the cytomegalovirus promoter) that preferentially replicates in tumors and helps stimulate antitumor immune responses.Methods We evaluated SKV-012’s safety and efficacy in preclinical models. …”
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Application of artificial intelligence-assisted Traditional Chinese medicine formula granules in bone and joint degenerative diseases in the field of holistic health by Xian-Quan Zhang, Xian-Quan Zhang, Xian-Quan Zhang, Xing-De Wei, Zhuo-Xu Gu, Guang-Hui Zhou, Chu-Jia Huang, Ming-Hui Luo, Ling-Feng Zeng, Ling-Feng Zeng, Ling-Feng Zeng, Wei-Yi Yang, Wei-Yi Yang

“…Traditional treatment methods face bottlenecks in long-term management, including drug side effects and low patient compliance. …”
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Anti-stigma campaign: the COVID-19 stigma and associated factors among Chinese young students by Cong Wang, Cong Wang, Yun-Fei Mu, Yun-Fei Mu, Jia Cai, Yu Wang, Zhong-Yue Deng, Zhong-Yue Deng, Ai-Ping Deng, Ai-Ping Deng, Hong-Jun Song, Hong-Jun Song, Tian-Ming Zhang, Xin-Yi Zhao, Yi-Yue Yang, Li Yin, Yi Huang, Yi Huang, Jian-Jun Luo, Mao-Sheng Ran, Mao-Sheng Ran

“…Logistic regression analysis identified risk factors for stigma, while Random Forest (RF) modeling ranked the importance of these factors.Results20,155 (24.3%) participants reported stigmatizing views toward COVID-19 patients. …”
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U-shaped association between ultra-processed food intake and overactive bladder in US adults: a national cross-sectional study by Zufa Zhang, Zufa Zhang, Li Chen, Long Lv, Long Lv, Wenkai Li, Wenkai Li, Bin Hou, Bin Hou, Sheng Guan, Sheng Guan, Zuyi Chen, Zuyi Chen, Danni He, Danni He, Hongxuan Song, Hongxuan Song, Weibing Sun, Weibing Sun, Feng Tian, Feng Tian, Fengze Jiang, Fengze Jiang, Sixiong Jiang, Sixiong Jiang

“…This study aimed to investigate the relationship between UPF consumption and the risk of OAB in U.S. adults.MethodsWe conducted a cross-sectional analysis using data from 23,482 participants in the National Health and Nutrition Examination Survey (NHANES). …”
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Association of advanced glycation end-product accumulation with overactive bladder in community-dwelling elderly: A cross-sectional Sukagawa study by Kenji Omae, Noriaki Kurita, Sei Takahashi, Shingo Fukuma, Yosuke Yamamoto, Shunichi Fukuhara

“…Objective: This study aimed to evaluate the influence of advanced glycation end-product (AGE) accumulation on the prevalence and severity of overactive bladder (OAB) in community-dwelling elderly adults. Methods: We conducted a cross-sectional study involving 269 Japanese community dwellers aged ≥75 years in 2015. …”
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Oxidative balance and survival in osteoporosis: how antioxidant diets and lifestyles reduce mortality risk by Ziyao Ding, Ziyao Ding, Ziyao Ding, Haixu Qi, Haixu Qi, Haixu Qi, Wenbo Li, Wenbo Li, Wenbo Li, Changchang Chen, Youwei Li, Jun Sun, Jun Sun, Maji Sun, Maji Sun, Maji Sun, Shuo Feng, Shuo Feng, Shuo Feng, Feng Yuan, Feng Yuan, Feng Yuan

“…This research aims to investigate the correlation between oxidative balance score (OBS) and all-cause mortality in individuals diagnosed with OP.MethodsThis study is based on data from the National Health and Nutrition Examination Survey (NHANES, 2005–2018), which covers 776 OP patients aged 50 or older. …”
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