Utilizing multiple diffusion metrics in evaluation of corticospinal tract injury in patients with glioblastoma by Ting Chen, Peipei Wang, Eryuan Gao, Jie Bai, Guohua Zhao, Kai Zhao, Gaoyang Zhao, Yu Zhang, Yong Zhang, Mengzhu Wang, Guang Yang, Boyan Xu, Xiaoyue Ma, Jingliang Cheng, Jingliang Cheng

“…Bilateral CSTs were reconstructed, and a comparative analysis of diffusion parameters was performed based on four imaging models between affected and healthy sides. …”
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Exploration of 3D Few-Shot Learning Techniques for Classification of Knee Joint Injuries on MR Images by Vinh Hiep Dang, Minh Tri Nguyen, Ngoc Hoang Le, Thuan Phat Nguyen, Quoc-Viet Tran, Tan Ha Mai, Vu Pham Thao Vy, Truong Nguyen Khanh Hung, Ching-Yu Lee, Ching-Li Tseng, Nguyen Quoc Khanh Le, Phung-Anh Nguyen

“…Few-shot learning (FSL) addresses this by enabling models to classify new conditions from minimal annotated examples, often leveraging knowledge from related tasks. …”
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Temporal Trends in Stroke Management and Outcomes Between 2011 and 2020 in South Korea: Results From a Nationwide Multicenter Registry by Tai Hwan Park, Keun‐Sik Hong, Yong‐Jin Cho, Wi‐Sun Ryu, Dong‐Eog Kim, Man‐Seok Park, Kang‐Ho Choi, Joon‐Tae Kim, Jihoon Kang, Beom‐Joon Kim, Moon‐Ku Han, Jun Lee, Jae‐Kwan Cha, Dae‐Hyun Kim, Jae Guk Kim, Soo Joo Lee, Jee‐Hyun Kwon, Wook‐Joo Kim, Dong‐Ick Shin, Kyu Sun Yum, Sung Il Sohn, Jeong‐Ho Hong, Jay Chol Choi, Byung‐Chul Lee, Kyung‐Ho Yu, Mi‐Sun Oh, Jong‐Moo Park, Kyusik Kang, Kyungbok Lee, Sang‐Hwa Lee, Hae‐Bong Jeong, Kwang‐Yeol Park, Ji Sung Lee, Juneyoung Lee, Philip B. Gorelick, Hee‐Joon Bae

“…We also seek to identify areas in need of improvement. Methods and Results This analysis involved patients with ischemic stroke or transient ischemic attack registered prospectively in the CRCS‐K‐NIH (Clinical Research Center for Stroke in Korea–National Institute of Health) registry between 2011 and 2020. …”
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Hepatitis B Virus Status and Clinical Outcomes in IgA Nephropathy by Mei-zhu Gao, Lin-lin Xu, Yang Li, Xin Wang, Pei Chen, Su-fang Shi, Li-jun Liu, Ji-cheng Lv, Fu-Yuan Hong, Hong Zhang, Xu-jie Zhou

“…Multivariable cause-specific hazards models to analyze the relationship between HBV states and IgAN progression. …”
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Investigation of the impact of service parameters on the degree of passenger satisfaction based on the application of the apparatus of neural networks by S. S. Pastukhov, K. V. Stel’Mashenko

“…Methodical and practical approaches are proposed to identify and compare the effect of service parameters on the level of passenger satisfaction on the basis of modeling using the apparatus of neural networks for conditions where the application of least squares correlation and regression analysis and mechanisms of order logistic regression are prognostically inefficient or excessively time consuming for analytical work. …”
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FEATURES OF APPLICATION OF FILTERS KALMAN-BJUSI IN ORIENTATION AND NAVIGATION COMPLEXES by A. S. Benkafo, A. A. Lobaty

“…On the basis of an optimum filtration theory the analysis of methodical errors which are possible at application an optimum estimation algorithm of stochastic system phase co-ordinates is carried out. …”
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FMO2+ cancer-associated fibroblasts sensitize anti-PD-1 therapy in patients with hepatocellular carcinoma by Hui Li, Wenxin Xu, Qinghai Ye, Qiang Yu, Jialei Weng, Shaoqing Liu, Minghao Xu, Yinghao Shen, Hui-Chuan Sun, Yufei Zhao, Peiyi Xie, Mincheng Yu, Bugang Liang, Junbo Chen

“…Mouse orthotopic HCC models and a coculture system were constructed, and cytometry by time-of-flight analysis was performed to investigate the functions and mechanisms of specific CAFs in the immune context of HCC.Results We identified a distinct flavin-containing monooxygenase 2 (FMO2)+ CAF subset associated with a favorable response to anti-PD-1 therapy and better clinical outcomes. …”
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National Outcomes of Venoarterial Extracorporeal Life Support in Patients with Chronic Kidney Disease by Oh Jin Kwon, Esteban Aguayo, Kevin Tabibian, Jeffrey Balian, Arjun Chaturvedi, Dariush Yalzadeh, Joseph Hadaya, Yas Sanaiha, Peyman Benharash

“…The prevalence of chronic kidney disease (CKD) in VA-ECMO patients remains unclear, and its relationship with outcomes is not well established. Methods: A retrospective analysis was conducted on patients (≥18 years) undergoing VA-ECMO using the 2019–2021 Nationwide Readmissions Database. …”
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Trained human bone marrow mesenchymal stem cells restore tissue immuno-microenvironment in fulminant hepatic failure mice by Bingqi Li, Xiaofei Zeng, Jing Jiang, Qian Zhou, Li Tong, Xi Liang, Jiaojiao Xin, Xi Chen, Xiao Wu, Yuheng Kong, Shiwen Ma, Jinjin Luo, Wei Qiang, Bing Zhu, Xinhua Luo, Jun Li, Dongyan Shi

“…This study aimed to clarify the trained-hBMSC (T-hBMSC) in restoring tissue immuno-microenvironment in fulminant hepatic failure (FHF) mice. Methods hBMSC trained with tumor necrosis factor-α and interferon-γ were phenotypically characterized in vitro. …”
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Exome sequencing revealed a novel homozygous variant in TRMT61 A in a multiplex family with atypical Cornelia de Lange Syndrome from Rwanda by Esther Uwibambe, Abdoulaye Yalcouyé, Elvis Twumasi Aboagye, Lettilia Xhakaza, Kalinka Popel, Norbert Dukuze, Thashi Bharadwaj, Carmen de Kock, Isabelle Schrauwen, Suzanne M. Leal, Leon Mutesa, Ambroise Wonkam

“…(Ala222Val)] inherited from both heterozygous parents. In silico analysis suggested that the variant substitutes a highly conserved amino acid, and 2-D structure modelling revealed a significant decrease in the stability of the protein. …”
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Targeting and cytotoxicity of chimeric antigen receptor T cells grafted with PD1 extramembrane domain by Ang Zhang, Shenyu Wang, Yao Sun, Yikun Zhang, Long Zhao, Yang Yang, Yijian Zhang, Lei Xu, Yangyang Lei, Jie Du, Hu Chen, Lian Duan, Mingyi He, Lintao Shi, Lei Liu, Quanjun Wang, Liangding Hu, Bin Zhang

“…Our attempt to devise a novel CAR structure capable of recognizing both tumor antigens and PDL1 encountered challenges since direct targeting of PDL1 resulted in systemic adverse effects. Methods In this research, we innovatively engineered novel CARs by grafting the PD1 domain into a conventional second-generation (2G) CAR specifically targeting CD19. …”
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HIF‐1α‐induced long noncoding RNA LINC02776 promotes drug resistance of ovarian cancer by increasing polyADP‐ribosylation by Yangjun Wu, Yu Zeng, Yong Wu, Xinyu Ha, Zheng Feng, Chaohua Liu, Ziqi Liu, Jiajia Wang, Xingzhu Ju, Shenglin Huang, Linhui Liang, Bin Zheng, Lulu Yang, Jun Wang, Xiaohua Wu, Shengli Li, Hao Wen

“…Abstract Background Chemoresistance remains a major hurdle in ovarian cancer (OC) treatment, as many patients eventually develop resistance to platinum‐based chemotherapy and/or PARP inhibitors (PARPi). Methods We performed transcriptome‐wide analysis by RNA sequencing (RNA‐seq) data of platinum‐resistant and ‐sensitive OC tissues. …”
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On Usage of Artificial Intelligence for Predicting Neonatal Diseases, Conditions, and Mortality: A Bibliometric Review by Flavio Leandro de Morais, Raysa Carla Leal da Silva, Anna Beatriz Silva, Estefani Pontes Simao, Maria Eduarda Ferro de Mello, Stephany Paula da Silva Canejo, Katia Maria Mendes, Waldemar Brandao Neto, Jackson Raniel Florencio da Silva, Maicon Herverton Lino Ferreira da Silva Barros, Patricia Takako Endo

“…Methods: This study conducts a bibliometric review of the use of artificial intelligence models in predicting neonatal diseases, conditions and mortality. …”
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State of nature 2023 terrestrial and freshwater animal dataset for the United Kingdom and its constituent countriesZenodo by Fiona Burns, Simone Mordue, Nida Al-Fulaij, Philipp Boersh-Supan, Katherine L. Boughey, Philip Briggs, Mark A. Eaton, Colin Harrower, Angus C. Jackson, Steve Langton, Francesca Mancini, David Noble, Chris R. Shortall, Chloë A. Smith, Robin J. Pakeman

“…Statistical methods partially controlled for the risk of bias and the noisy nature of such occupancy data. …”
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Developing and validating utility parameters to establish patient-reported outcome-based perioperative symptom management in patients with lung cancer: a multicentre, prospective,... by Rui Zhang, Wei Dai, Qiang Li, Shaohua Xie, Qiuling Shi, Yuanqiang Zhang, Wenhong Feng, Xiaoqing Liao, Yunfei Mu, Xing Wei, Chuanmei Wu, Heling Zhou, Xuemei Cheng, Yanhua Jiang, Jintao He, Xiaojun Yang

“…We aim to develop a perioperative symptom scale (PSS) for monitoring, to determine the optimal time points for symptom assessment and to define the alert thresholds for medical intervention.Methods and analysis This study will prospectively recruit 300 patients undergoing lung cancer surgery in six hospitals. …”
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γ-Secretase modulator resistance of an aggressive Alzheimer-causing presenilin mutant can be overcome in the heterozygous patient state by a set of advanced compounds by Johannes Trambauer, Rosa Maria Rodriguez Sarmiento, Holly J. Garringer, Katja Salbaum, Liliana D. Pedro, Dennis Crusius, Ruben Vidal, Bernardino Ghetti, Dominik Paquet, Karlheinz Baumann, Lothar Lindemann, Harald Steiner

“…Methods Mouse embryonic fibroblast and induced pluripotent stem cell-derived neuronal PS1 L166P knock-in (KI) cell models were treated with various GSMs and Aβ responses were assessed by immunoassays and/or gel-based analysis. …”
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Monocyte-derived APCs are central to the response of PD1 checkpoint blockade and provide a therapeutic target for combination therapy by Louis Boon, Matheus H W Crommentuijn, Sjoerd T T Schetters, Laura J W Kruijssen, Yvette van Kooyk, Ernesto Rodriguez, Jan Van den Bossche, Joke M M Den Haan

“…It is still unclear how these APCs develop and function before and during αPD1 ICB or how they are associated with tumor rejection.Methods Here, we used B16 mouse melanoma and MC38 colorectal carcinoma tumor models, which show differential responses to αPD1 ICB. …”
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Association of fall risk-increasing drugs with falls in generally healthy older adults: a 3-year prospective observational study of the DO-HEALTH trial by Caroline de Godoi Rezende Costa Molino, Catherine K. Forster, Maud Wieczorek, E. John Orav, Reto W. Kressig, Bruno Vellas, Andreas Egli, Gregor Freystaetter, Heike A. Bischoff-Ferrari, the DO-HEALTH Research Group

“…The aim of this study was to investigate the association between FRID use at baseline and the prospective incidence rates of total, injurious and recurrent falls in community-dwelling older adults. Methods This is a 3-year observational analysis of DO-HEALTH, a randomized controlled trial, among community-dwelling adults aged ≥ 70 years without major diseases at baseline. …”
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Predictive Validity of Hospital-Associated Complications of Older People Identified Using Diagnosis Procedure Combination Data From an Acute Care Hospital in Japan: Observational S... by Seigo Mitsutake, Tatsuro Ishizaki, Shohei Yano, Takumi Hirata, Kae Ito, Ko Furuta, Yoshitomo Shimazaki, Hideki Ito, Alison Mudge, Kenji Toba

“…Generalized linear regression models were used to examine the associations between HAC-OP-DPC and LOS, and logistic regression models were used to examine the associations between HAC-OP-DPC and discharge to other hospitals and long-term care facilities (LTCFs). …”
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A cross-sectional and longitudinal evaluation of serum creatinine as a biomarker in spinal muscular atrophy by Xin Zhao, Zhenxiang Gong, Han Luo, Zehui Li, Rong Gao, Kangqin Yang, Wenhua Deng, Sirui Peng, Li Ba, Yang Liu, Min Zhang

“…The association between Crn and disease severity was investigated through partial rank correlation analysis and linear mixed models while accounting for age, gender, and BMI. …”
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