Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants... by J. C. vanMaanen, F. C. Bach, J. W. Snuggs, K. Ito, M. H. M. Wauben, C. L. Le Maitre, M. A. Tryfonidou

“…Therefore, this study explores whether NC‐EVs modulate interleukin (IL)‐1β‐mediated pro‐inflammatory responses in the degenerating disc. Methods This study utilized two IL‐1β induced pro‐catabolic culture models; a dog 3D nucleus pulposus (NP) cell pellet culture and a human patient‐derived, ex vivo NP tissue culture system. …”
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Early diagnosis and survival outcomes in silicosis: a retrospective cohort study of 11,809 patients in Guangdong Province, China (1956–2020) by Chunyue Fan, Yuhao Wang, Yuhao Wang, Jingjing Chen, Qiaoli Wei, Shijie Hu, Lihua Xia, Jiawen Huang, Weihui Liang, Lin Wu, Xudong Li

“…This study aimed to evaluate the association between early diagnosis and survival in silicosis patients and assess the impact of delayed diagnosis on mortality.MethodsA retrospective cohort study analyzed 11,809 silicosis patients diagnosed between 1956 and 2020 in Guangdong Province, China. …”
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Prognostic value of albumin-corrected anion gap in critically ill patients with sepsis-associated liver injury: a retrospective study by Jianjun Wang, Yonghai Peng, Zhaohui Hu, Xi Chen, Sirui Chen, Pei Yang, Xintao Zeng, Decai Wang

“…The optimal cutoff value for ACAG was established using R statistical software. Kaplan-Meier analysis was conducted to compare mortality risks between the two groups, while multivariable Cox proportional hazards regression models were employed to examine the association between ACAG and mortality risk in SALI patients. …”
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Awareness and intention to use event‐driven and long‐acting injectable pre‐exposure prophylaxis among adolescent and young men who have sex with men and transgender women in Brazil... by Laio Magno, Beo Oliveira Leite, Alexandre Grangeiro, Lorenza Dezanet, Fabiane Soares, Inês Dourado

“…Binomial logistic regression models analysed factors associated with the intention to use event‐driven and long‐acting injectable PrEP. …”
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The incidence and influencing factors of type 2 diabetes mellitus in Chinese adults in 10 provinces: a prospective cohort study by Shujuan Li, Tingfang Ai, Run Zhang, Xiaoqing You, Jianhong Li

“…Based on the national representative data, we investigated the incidence and influencing factors of DM in Chinese adults. Methods Based on 2010 China Chronic Disease and Risk Factors Surveillance (CCDRFS), a follow-up survey was conducted in 20 monitoring points from ten provinces of China in 2016–2017. …”
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DEVELOPING YOUTH RESILIENCE IN CONDITIONS OF SOCIAL INSTABILITY AND WAR by Vira Syniakova, Yuliia Bokhonkova, Mykyta Minin

“…Future research should focus on the long-term effects of resilience development programs and explore scalable models for broader implementation across educational and social institutions. …”
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Urban greenspace and cardiovascular disease comorbidity at breast cancer diagnosis in the US: regional, racial/ethnic, and socioeconomic variations among older women by Jean C. Bikomeye, Emily L. McGinley, Yuhong Zhou, Sergey Tarima, Jamila L. Kwarteng, Andreas M. Beyer, Tina W.F. Yen, Aaron N. Winn, Kirsten M.M. Beyer

“…Objective To investigate the association between urban greenspace and cardiovascular disease (CVD) comorbidity at breast cancer (BC) diagnosis among older women, and explore regional, racial/ethnic, and socioeconomic differences.Study design A cross-sectional analysis of population-based registry data.Methods Using the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database, data on women aged 66-90 diagnosed with BC (2010-2017) were analyzed. …”
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Development of a Mobile Intervention for Procrastination Augmented With a Semigenerative Chatbot for University Students: Pilot Randomized Controlled Trial by Seonmi Lee, Jaehyun Jeong, Myungsung Kim, Sangil Lee, Sung-Phil Kim, Dooyoung Jung

“…ObjectiveWe intended to determine the benefits of the Moa-integrated to-do app over the app without Moa by verifying behavioral and cognitive changes, analyzing the influence of engagement patterns on the changes, and exploring the user experience. MethodsThe developed chatbot Moa guided users over 30 days in terms of self-observation, strategy establishment, and reflection. …”
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Understanding Challenges and Emotions of Informal Caregivers of General Older Adults and People With Alzheimer Disease and Related Dementia: Comparative Study by Nova Mengxia Huang, Liang Ze Wong, Shirley S Ho, Bryan Timothy

“…Using topic modeling, we identified topics discussed by caregivers in the collected posts. …”
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Effects of the Duration of Wheat and Maize Straw Returning on Rill Erosion Resistance in Brown Soil in the Earth-rocky Mountainous Area of Northern China by ZHANG Hanyu, LI Jiaqian, ZHAO Yajie, LI Jingjiang, LIU Zhihua, FANG Nufang, LIU Qianjin

“…［Objective］ Research on the effects of the duration of straw returning on rill erosion resistance can provide scientific evidence for rill erosion modeling and controlling in sloping farmland. ［Methods］ Taking straw returning durations of 0 years (CK), 3—4 years (R1), 5—6 years (R2), 7—8 years (R3), 9—10 years (R4), 15 years (R5), and 20 years (R6) as the study subjects, soil samples were collected and analyzed. …”
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Dairy intake and cognitive function in older adults in three cohorts: a mendelian randomization study by Natalia Ortega, Nick J. Mueller, Abbas Dehghan, Tosca O. E. de Crom, Armin von Gunten, Martin Preisig, Pedro Marques-Vidal, Marco Vinceti, Trudy Voortman, Nicolas Rodondi, Patricia O. Chocano-Bedoya

“…We used it to assess the effect of long-term consumption of total and non-fermented dairy on cognitive function. Methods We included 43,836 individuals over 55 years old with genotyping, dietary data, and cognitive function measurements from three population-based studies: CoLaus|PsyCoLaus (Switzerland), the Rotterdam Study (the Netherlands) and the Canadian Longitudinal Study on Aging (CLSA - Canada). …”
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Seasonal variation of Microsporidia MB infection in Anopheles gambiae and Anopheles coluzzii in two different geographical localities in Benin by Genevieve Tchigossou, Michel Lontsi-Demano, Eric Tossou, Pierre-Marie Sovegnon, Romaric Akoton, Danahe Adanzounon, Camille Dossou, Massioudou Koto, Azarath Ogbon, Marie Gouété, Godfrey Nattoh, Rousseau Djouaka

“…This study aimed to determine the presence and prevalence of Microsporidia MB in rice fields in Benin during both the dry and wet seasons. Methods Anopheles larvae and adults were collected from rice fields and houses around rice fields in two locations (Koussin-Lélé and Magoumi). …”
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Strategies to Improve Health Care Provider Prescription of and Patient Adherence to Guideline-Recommended Cardiovascular Medications for Atherosclerotic Occlusive Disease: Protocol... by Aidan M Kirkham, Dean A Fergusson, Justin Presseau, Daniel I McIsaac, Risa Shorr, Derek J Roberts

“…ObjectiveWe aim to systematically review and meta-analyze RCTs examining the effectiveness of implementation or adherence-supporting strategies for improving health care provider prescription of, or patient adherence to, guideline-recommended cardiovascular medications in patients with atherosclerotic occlusive disease. MethodsWe designed and reported the protocol according to the PRISMA-P (Preferred Reporting Items for Systematic Review and Meta-Analysis-Protocols) statement. …”
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Pragmatic performance, its relationship with symptom severity, and early clinical predictors of pragmatics in 5 ~ 6-year-old children with autism spectrum disorder by Lu Qian, Ning Ding, Hui Fang, Ting Xiao, Bei Sun, HuiYun Gao, XiaoYan Ke

“…However, minimal longitudinal research has focused on defining early predictors of pragmatic development in children with autism spectrum disorder (ASD). Methods In the present study, 71 children with ASD and 38 age- and gender- matched 24- to 30-month-old typically developing (TD) children were enrolled. …”
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Feasibility, Added Value, and Radiation Dose of Combined Coronary CT Angiography and Stress Dynamic CT Myocardial Perfusion Imaging in Moderate Coronary Artery Disease: A Real-Worl... by Marco Fogante, Enrico Paolini, Fatjon Cela, Paolo Esposto Pirani, Liliana Balardi, Gian Piero Perna, Nicolò Schicchi

“…Objective: We aimed to evaluate the feasibility, added value, and radiation dose of coronary computed tomography angiography (CCTA) and stress dynamic CT myocardial perfusion imaging (MPI) in patients with coronary artery disease (CAD) in a real-world setting. Materials and Methods: This retrospective study included 65 patients (mean age: 51.2 ± 11.5 years; 21 female) with moderate CAD, selected from the Radiological Database of our hospital between May 2022 and December 2024. …”
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Socioeconomic factors and test preparation strategies are related to success on the USMLE Step 2 clinical knowledge (CK) exam: a single-institution study by Hila Ghersin, Michelle C. Gulfo, Bailey A. Frohlich, Scott M. Wilson, Ashley A. Berlot, Janice S. Zhang, Rohan Kankaria, Ashley Radparvar, Juan Lin, Michelle A. Blackmore, Amanda C. Raff

“…In this study, we investigated predictors of Step 2 CK success across two years at one institution. Methods A survey regarding Step 2 CK exam preparation and demographic factors was administered to two student cohorts at a New York medical school in 2022 and 2023. …”
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Comparison of Gait Parameters Collected Across Two Commercially Available Gait Systems in Older Adults by Alexandria Hoang, Jeannette Mahoney, Ying Jin, Sofiya Milman, Nir Barzilai, Joe Verghese, Emmeline Ayers

“…We aim to determine whether gait parameters obtained from GAITRite and processed using two software systems can be reliably pooled for use in studies with older adults. <b>Methods</b>: Baseline gait data from 193 older adults aged 64–94 years old were examined. …”
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Associations Between Shift Work, Sociodemographic and Lifestyle Characteristics, Body Measurements, and MASLD by Javier Tosoratto, Pedro Juan Tárraga López, Ángel Arturo López-González, Carla Busquets-Cortes, Joan Obrador de Hevia, José Ignacio Ramirez-Manent

“…Multinomial logistic regression models were used to assess independent associations between shift work and high-risk MASLD scores. …”
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Quality of life among residents of informal urban settlements during the COVID-19 pandemic in Salvador, Brazil by Albert I Ko, Federico Costa, Hammed Mogaji, Nivison Nery, Hernan D Argibay, Jaqueline S Cruz, Ianei O Carneiro, Ricardo Lustosa, Mike Begon, Hussein Khalil

“…However, there is limited information on the health-related quality of life (HRQOL) and indirect consequences of non-pharmaceutical interventions implemented during the pandemic.Methods We leveraged on an ongoing prospective open-cohort survey and performed a cross-sectional analysis of data collected between November 2021 and July 2022 among 793 residents above age 5 in a large slum community in the city of Salvador, Brazil. …”
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Adjusting Aspergillus niger pellet diameter, population heterogeneity, and core architecture during shake flask cultivation by K. Engelbert, C. Deffur, T. C. Cairns, F. Zhang, T. Kheirkhah, H. Winter, S. Junne, P. Neubauer, H. Briesen, V. Meyer

“…Conclusions This study identifies simple methods for adjusting macromorphology and heterogeneity, which will enable facile testing of different macromorphologies for maximizing product titres. …”
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