Self-reported outcomes following lower extremity, carotid and aortic artery disease: protocol for the Danish Vascular (DanVasc) survey by Jes Sanddal Lindholt, Britt Borregaard, Kim Christian Houlind, Marie Dahl, Jacob Budtz-Lilly, Jonas Peter Eiberg, Christian Nikolaj Petersen, Saeid Shahidi

“…Therefore, the Danish Vascular (DanVasc) survey aims to describe self-reported health status, health literacy, medication adherence and loneliness, including changes over time, and investigate characteristics associated with worse self-reported health at baseline and their associations with poorer outcomes within 1 year (healthcare utilisation and mortality) in patients with LEAD, SCS and AAA.Methods and analysis The DanVasc survey, a national prospective cohort study combining survey data measured at several time points with register-based data, includes validated patient-reported outcome measures (PROMs) and ancillary questions developed with patient representatives. …”
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The effects of orphanhood and lack of parental care on child vaccination: analyses of 189 cross-sectional UNICEF Multiple Indicator Cluster Surveys from 82 countries, 2005–2022Rese... by Mira Johri, Mehr Munir, Rose Anne Medeiros, Lumana Shakya, Blaine Damte, Anna Bolgrien

“…We investigated whether orphans and children without parental care were at risk of sub-optimal vaccination. Methods: Cross-sectional analyses of 189 UNICEF Multiple Indicator Cluster Surveys from 82 predominantly low- and middle-income countries, conducted from January 1, 2005 to December 31, 2022. …”
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Results from AD-HEARING (ADherence to and adjustment of HEARING aids in clinical routine care as preventive dementia strategy): a prospective 6-month follow-up study on cognition a... by Michael Belz, Sebastian Gmeinwieser, Mona Abdel-Hamid, Mona Abdel-Hamid, Robert Kühler, Jenny Blum, Philipp Hessmann, Nicola Strenzke, Claudia Bartels

“…Hearing aid use might reduce this risk by preserving cognitive and psychological functions.ObjectiveThis study aims to investigate the influence of ARHL and hearing aid use on cognition and different aspects of psychological well-being.MethodsDuring 05/2021 and 05/2023, 31 subjects with audiometrically confirmed ARHL were included and 28 underwent follow-up 6 months later (final analysis sample). …”
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Health insurance status and severe mpox disease outcomes among sexual minority men in NYC: a retrospective cohort study by Ofole Mgbako, Cecilia Castellano, Kathryn Jano, Anthony Lo Piccolo, Madeline A. DiLorenzo, Dorothy Knutsen, Yusra Shah, Joyce C. Pressley, Dustin T. Duncan, Jason Felder, Dana Mazo

“…We sought to characterize patients diagnosed with mpox in New York City (NYC) and examine associations between insurance status and mpox severity score (mpox-SS). Methods We included 143 patients aged 18 years and older between May 1, 2022, and December 31, 2023, with confirmed mpox identified through the electronic medical record. …”
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Effects of otolaryngological diseases on sleep quality, anxiety, and depression: a multicenter observational study by Cheng-Lin Qi, Qin-Ying Wang, Mi Wang, Lin-Bin Cai, Meng-Qing Shen, Kan Liu, Jin-Long Zhu, Cong Wang, Qi-Bing Chen, Ting-Ting Wu, Shui-Hong Zhou, Jin-Hua Pan

“…Multivariable polynomial linear regression models explored the impact of different otolaryngological diseases on anxiety, depression and sleep quality, and mediation analysis explored the interaction mechanisms. …”
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Correlation of cognitive impairment with Mediterranean diet and mortality: a prospective cohort study by Ling Li, Xiaoxiao Zheng, Hongyue Ma, Mingxia Zhu, Xiuli Li, Xinhong Feng

“…This study aims to explore whether there is an interaction between the degree of adherence to the Mediterranean diet and cognitive impairment on long-term mortality outcomes.MethodsThe study included 2,520 participants from the National Health and Nutrition Examination Survey (NHANES) conducted between 2011 and 2014. …”
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Comparison of wind-farm control strategies under realistic offshore wind conditions: wake quantities of interest by K. Brown, G. Yalla, L. Cheung, J. Frederik, D. Houck, N. deVelder, E. Simley, P. Fleming

“…Two inherently different wind-farm control methods have been identified in the literature: wake steering (WS) and active wake mixing (AWM). …”
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Comparative cardiovascular outcomes of aripiprazole vs. risperidone in patients with type 2 diabetes and schizophrenia: a retrospective cohort study by Yi-Ting Yeh, Shih-Chang Lo, Chien-Ning Huang, Chien-Ning Huang, Chien-Ning Huang, Yi-Sun Yang, Yi-Sun Yang, Pei-Lun Liao, Edy Kornelius, Edy Kornelius

“…We aimed to compare major adverse cardiovascular events (MACEs) in patients with co-occurring T2DM and schizophrenia treated with aripiprazole versus risperidone.MethodsWe conducted a multi-center retrospective cohort study within the TriNetX US Collaborative Network (2014–2024). …”
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The Role of Muscle Density in Predicting the Amputation Risk in Peripheral Arterial Disease: A Tissue Composition Study Using Lower Extremity CT Angiography by Yueh-Hung Lin, Pei-Shan Tsai, Chung-Lieh Hung, Mirza Faisal Beg, Hung-I Yeh, Chun-Ho Yun, Ming-Ting Wu

“…While muscle volume and vascular severity is often considered in risk prediction, the prognostic value of muscle density remains underexplored. <b>Methods</b>: In this exploratory study, we retrospectively analyzed 134 patients undergoing lower-limb computed tomography angiography between January 2018 and December 2023. …”
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Association of Life’s Essential 8 with incidence of heart failure modified by depressive symptoms: a prospective cohort study from UK Biobank by Wei Hu, Chun-Hua Zhao, Jia-Ning Wang, Zhen-Zhen Shen, Ge Tian, Yue-Qing Huang, Bao-Peng Liu, Cun-Xian Jia

“…We aimed to prospectively investigate the independent, joint, and interactive associations of LE8 and depressive symptoms with HF incidence. Methods A total of 336,939 participants recruited from UK Biobank without HF, coronary heart disease, and stroke were included in the cohort study. …”
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Radiotherapy to the prostate for men with metastatic prostate cancer in the UK and Switzerland: Long-term results from the STAMPEDE randomised controlled trial. by Chris C Parker, Nicholas D James, Christopher D Brawley, Noel W Clarke, Adnan Ali, Claire L Amos, Gerhardt Attard, Simon Chowdhury, Adrian Cook, William Cross, David P Dearnaley, Hassan Douis, Duncan C Gilbert, Clare Gilson, Silke Gillessen, Alex Hoyle, Rob J Jones, Ruth E Langley, Zafar I Malik, Malcolm D Mason, David Matheson, Robin Millman, Mary Rauchenberger, Hannah Rush, J Martin Russell, Hannah Sweeney, Amit Bahl, Alison Birtle, Lisa Capaldi, Omar Din, Daniel Ford, Joanna Gale, Ann Henry, Peter Hoskin, Mohammed Kagzi, Anna Lydon, Joe M O'Sullivan, Sangeeta A Paisey, Omi Parikh, Delia Pudney, Vijay Ramani, Peter Robson, Narayanan Nair Srihari, Jacob Tanguay, Mahesh K B Parmar, Matthew R Sydes, STAMPEDE Trial Collaborative Group

“…<h4>Methods and findings</h4>Patients were randomised at secondary care sites in the United Kingdom and Switzerland between January 2013 and September 2016, with 1:1 stratified allocation: 1,029 to standard of care (SOC) and 1,032 to SOC+RT. …”
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Hysterectomy is not associated with increased risk of urinary incontinence—a northern Finland birth cohort 1966 study by Heini Salo, Roosa Manninen, Anna Terho, Johanna Laru, Henri Sova, Sari Koivurova, Henna‐Riikka Rossi

“…In our population‐based cohort study, we aimed to assess the independent effect of hysterectomy on the risk of de novo UI. Material and Methods This is a population‐based cohort study on the women of the Northern Finland Birth Cohort 1966 (n = 5889). …”
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Ethnic disparities in the association between maternal socioeconomic status and childhood anemia in Peru: a nationwide multiyear cross-sectional studyResearch in context by Ali Al-kassab-Córdova, Claudio Intimayta-Escalante, Pamela Robles-Valcarcel, Diego Urrunaga-Pastor, Baltica Cabieses

“…Therefore, the current study aimed to explore ethnic disparities in the association between maternal SES on childhood anemia in Peru. Methods: Using data from the 2017 to 2023 Peruvian Demographic and Health Survey, we conducted a cross-sectional study including children aged 6–59 months with their respective mothers. …”
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ARM-X: an adaptable mesenchymal stromal cell-based vaccination platform suitable for solid tumors by Jean Pierre Bikorimana, Nehme El-Hachem, Gabrielle A. Mandl, Daniela Stanga, Jamilah Abusarah, Roudy Farah, Marina P. Gonçalves, Perla Matar, Malak Lahrichi, Sebastien Talbot, Moutih Rafei

“…A leading variant, AccuTOX®, was selected for that purpose. Methods Several functional studies, including a series of antigen cross-presentation assays, were conducted using the SIINFEKL-specific T-cell clone B3Z. …”
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Aminoquinazolin-4(3H)-one derivatives as multitargeting therapeutics in Alzheimer's disease by Tajamul Hussain, Salman Alrokayan, Dilawar Hussain, Khurram Shoaib, Syeda Abida Ejaz, Steven Ford, Jamshed Iqbal

“…Additionally, in-silico ADME modeling was utilized to analyze the pharmacokinetic profile. …”
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Elevated remnant cholesterol and triglycerides are predictors of increased total mortality in a primary health care population of 327,347 patients by Anna Elise Engell, Lise Bathum, Volkert Siersma, Christen Lykkegaard Andersen, Bent Struer Lind, Henrik Løvendahl Jørgensen

“…Additionally, the impact of lipid-lowering treatment was evaluated. Methods Observational cohort study based on the first lipid panel measurement from 327,347 patients from general practice in the Capital Region of Denmark between 2001 and 2018. …”
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Cardiac biomarkers for screening and prognostication of cardiac dysfunction in critically ill patients by Oscar Cavefors, Freyr Einarsson, Jakob Holmqvist, Odd Bech‐Hanssen, Sven‐Erik Ricksten, Björn Redfors, Jonatan Oras

“…Abstract Aims This study aimed to assess the use of high‐sensitivity troponin T (hsTNT) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) in screening for cardiac dysfunction [left ventricular (LV) systolic or diastolic dysfunction or right ventricular (RV) dysfunction] in mixed intensive care unit (ICU) patients and establish whether these biomarkers are independently associated with an increased risk of death. Methods We performed a secondary analysis of a single‐centre prospective observational study in which consecutive ICU patients were examined with transthoracic echocardiography (TTE) and cardiac biomarkers. …”
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Outdoor light spending time, genetic predisposition and incident Parkinson’s disease: the mediating effect of lifestyle and vitamin D by Yumei Huang, Shufan Tian, Kangli Qiu, Jinchi Xie, An Pan, Gang Liu, Yunfei Liao

“…However, the interaction of genetic predisposition and the potential role of lifestyle risk factors in mediating this association remains unclear from prospective evidence. Methods A cohort study based on the UK Biobank enrolled participants between 2006 and 2010, with the latest follow-up in November 2022. …”
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Cardiovascular Diseases Increase Cancer Mortality in Adults: NHANES‐Continuous Study by Omar M. Makram, Tochukwu Okwuosa, Daniel Addison, Jorge Cortes, Susan Dent, Malcolm Bevel, Sarju Ganatra, Sadeer Al‐Kindi, Catherine C Hedrick, Neal L Weintraub, Xiaoling Wang, Avirup Guha

“…Although our previous study detected a relationship between CVD and cancer incidence, limited evidence is available regarding the relationship between CVD, cardiovascular risk factors, and cancer mortality. Methods and Results A prospective cohort study using data from the continuous NHANES (National Health and Nutrition Examination Survey, 1999–2016) merged with Medicare and National Death Index mortality data, through December 31, 2018. …”
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Evaluation of Self-Regulating Doped Ferrite Nanoparticles with Glucose, Chitosan, and Poly-Ethylene Glycol Coatings for Hyperthermia and Dual Imaging by Negri A, Conti A, Milan E, Forlin E, Gherlinzoni F, Morana G, Gottardi M, Matteazzi P, Speghini A, Bongers A, Marzola P

“…The NPs were assessed for their physicochemical attributes, magnetic fluid hyperthermia (MFH) efficacy, dual-imaging capabilities in Magnetic Resonance Imaging (MRI) and Magnetic Particle Imaging (MPI), cytocompatibility, and cellular uptake.Methods: Physicochemical characterization was conducted using Fourier-transform infrared spectroscopy (FTIR), dynamic light scattering (DLS), and zeta potential measurements. …”
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