FPG Score: A Rapid Admission‐Based Tool for Predicting In‐Hospital Mortality in Elderly Hip Fracture Patients by Marcello Covino, Guido Bocchino, Maria Beatrice Bocchi, Chiara Barbieri, Benedetta Simeoni, Antonio Gasbarrini, Francesco Franceschi, Giulio Maccauro, Raffaele Vitiello

“…However, existing risk prediction models, such as the Nottingham Hip Fracture Score (NHFS) and the Charlson Comorbidity Index (CCI), require laboratory or postoperative data, delaying risk stratification. …”
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Association between insulin resistance-related lipid indices and arthritis: a U. S. cross-sectional study by Ao Wu, Haodong Teng, Xiaoxia Wang, Ketao Shi, Zhi Gao, Honghao Xu, Liang Yue

“…This study used cross-sectional data to explore lipid-related indicators and arthritis risk.Methods18,683 participants were involved in this study, selected from the NHANES database covering the period from 2001 to 2018. …”
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Effects of different phosphate lowering strategies in patients with CKD on laboratory outcomes: A systematic review and NMA. by Nigar Sekercioglu, Argie Angeliki Veroniki, Lehana Thabane, Jason W Busse, Noori Akhtar-Danesh, Alfonso Iorio, Luciane Cruz Lopes, Gordon H Guyatt

“…We calculated direct, indirect and network meta-analysis estimates using random-effects models. We applied the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach to rate the quality of evidence for each pairwise comparison.…”
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Targeted Glioma Therapy via TMVP1 Peptide-Modified FLT4 Liposomes: A Novel Molecular Probe Strategy by Zhou Y, Chen L, Shang C, Hong Y, Zhang H

“…By functionalizing TMZ-loaded liposomes with TMVP1 (TMZ@Lip-TMVP1), we aimed to enhance glioma-specific targeting and therapeutic efficacy.Methods: FLT4 was validated as a therapeutic target for glioma by bioinformatics analysis, RT-qPCR, and immunofluorescence experiments. …”
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The role of resilience in the transition of suicidal indicators among Chinese children and adolescents: a nested case-control study by Xin Tian, Linling Jiang, Shuqing Liu, Yandie He, Guiqing Zheng, Xinyi Liu, Xiang Wang, Yi Xiang, Jin Lu, Yuanyuan Xiao

“…This study examined the role of resilience in preventing the transition of suicidal indicators among children and adolescents. Methods A case-control study nested within a two-wave longitudinal survey was conducted in Yunnan province, China, involving 5,924 children and adolescents. …”
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Clinical insights into the role of bepridil in recurrence prevention after ablation of persistent atrial fibrillation by Moyuru Hirata, Koichi Nagashima, Ryuta Watanabe, Yuji Wakamatsu, Naoto Otsuka, Shu Hirata, Masanaru Sawada, Yuji Saito, Sayaka Kurokawa, Kenta Murotani, Yasuo Okumura

“…Baseline characteristics, procedural details, and outcomes were compared. Kaplan–Meier analysis and Cox regression models were used to evaluate AF/atrial tachycardia (AT) recurrence, with bepridil use treated as a time‐dependent covariable. …”
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Protocol for a randomized controlled trial of transdermal continuous oxygen therapy for surgical site wound healing after lower extremity revascularization by Khanjan Nagarsheth, MD, Georges Jreij, MD, Eleanor Dunlap, DNP, Shannon Hawkins, DNP, Rachel White, BSN, Areck Ucuzian, MD, PhD, Brajesh K. Lal, MD

“…A centralized randomization system will ensure balanced allocation, and blinded evaluators will assess wound images to reduce bias. Statistical analysis will include mixed models for repeated measures and Barnard’s test for SSI rates. …”
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The Effect of Red Ginger Extract, Klanceng Honey, and Their Combination on Blood Sugar, Cholesterol, and Blood Viscosity of Patients With Diabetes Mellitus by Mardi Hartono, Sunarto Sunarto, Supriyo Supriyo, Sudirman Sudirman, Maslahtul Inayah

“…Bivariate and mathematical general linear models (GLM) were applied with a significance level of 0.05. …”
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The diagnostic value of IL-6 and thymidine phosphorylase in the progression of osteosarcoma by Bushra AM Abdul Azeez, Ghufran Salman Abd Alhussain, Rabab Alhosainy Salman, Ali A. Al-Fahham

“…The aim of this study is to investigate the diagnostic role of thymidine phosphorylase and IL-6 in the pathogenesis and progression in patients with osteosarcoma. Materials and methods Thirty patients diagnosed with osteosarcoma (with age ranging between 15–44 years) were included in the current study. …”

Preterm preeclampsia screening and prevention: a comprehensive approach to implementation in a real-world setting by Stefania Ronzoni, Shamim Rashid, Aimee Santoro, Elad Mei-Dan, Jon Barrett, Nanette Okun, Tianhua Huang

“…This study assesses the feasibility of implementing preterm preeclampsia screening and prevention by leveraging information from our current aneuploidy screening program in a real-world setting with geographic separation clinical site and laboratory analysis site. Methods A prospective cohort study involved pregnant individuals undergoing nuchal translucency scans between 11 and 14 weeks. …”
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Factors associated with going outdoors frequently: a cross-sectional study among Swiss community-dwelling older adults by Christophe Büla, Laurence Seematter-Bagnoud, Brigitte Santos-Eggimann, Julia Spaltenstein, Helene Krief

“…Objective This study examines potential risk and protective factors associated with going outdoors frequently among older persons, and whether these factors vary according to physical limitations.Design Cross-sectional analysis.Setting and participants Community-dwelling participants of the Lausanne cohort Lc65+ in 2016, aged 68–82 years (n=3419).Methods Associations between going outdoors frequently and physical limitations, sociodemographic, health, psychological and social variables were examined using logistic regression models. …”
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Integrating the Interleukins in the Biomarker Panel for the Diagnosis and Prognosis of Patients with Acute Coronary Syndromes: Unraveling a Multifaceted Conundrum by Amalia-Stefana Timpau, Egidia-Gabriela Miftode, Irina-Iuliana Costache-Enache, Antoniu-Octavian Petris, Ionela-Larisa Miftode, Ivona Mitu, Radu-Stefan Miftode

“…Logistic regression models confirmed NT-proBNP and IL-10 as mortality predictors. …”
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Long-term anti-SARS-CoV-2 antibody trajectories after neutralizing monoclonal antibody treatment. by Elizabeth S Munroe, Greg A Grandits, Robert C Hyzy, Hallie C Prescott, Thomas W Barrett, Robin L Dewar, Nicole Engen, Anna L Goodman, Timothy J Hatlen, Helene Highbarger, Thomas L Holland, Gareth Hughes, Tomas O Jensen, Muhammad A Khan, Ioannis Kalomenidis, Nayon Kang, Sylvain Laverdure, Prasad Manian, Vidya Menon, Ravi Patel, Srikanth Ramachandruni, Tauseef Rehman, Kathryn Shaw-Saliba, Birgit Thorup Røge, David M Vock, Amy C Weintrob, Barnaby E Young, Anne P Frosch, STRIVE Network and Therapeutics for Inpatients with COVID-19 (TICO) study groups

“…Linear mixed effects models were fit to compare the longitudinal trajectory between treatment and placebo groups.…”
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What’s Going On With Me and How Can I Better Manage My Health? The Potential of GPT-4 to Transform Discharge Letters Into Patient-Centered Letters to Enhance Patient Safety: Prospe... by Felix Eisinger, Friederike Holderried, Moritz Mahling, Christian Stegemann–Philipps, Anne Herrmann–Werner, Eric Nazarenus, Alessandra Sonanini, Martina Guthoff, Carsten Eickhoff, Martin Holderried

“…We evaluated how effectively and comprehensively GPT-4 identified and transferred patient safety–relevant information from the discharge letters to the transformed patient letters. MethodsThree discharge letters were created based on common medical conditions, containing 72 patient safety–relevant pieces of information, referred to as “learning objectives.” …”
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Exploring the relationship between vitamin B12, methylmalonic acid levels and all-cause mortality in heart failure populations: insights from the NHANES database by Wei Yu, Yao Wang, Yao Wang, Yao Wang, Yulu Zhou, Danyu Wu, Danyu Wu, Danyu Wu

“…Despite being a specific and sensitive marker for this deficiency, the study of methylmalonic acid (MMA) in the context of HF has been infrequent.MethodsSeven hundred and forty-seven individuals with HF were incorporated in this cross-sectional study who participated in the National Health and Nutrition Examination Survey (NHANES) from two periods, 1999 to 2004, and 2011 to 2014. …”
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Neonatal outcome following metformin‐treated gestational diabetes mellitus: A population‐based cohort study by Johanna Molin, Magnus Domellöf, Christel Häggström, Eszter Vanky, Itay Zamir, Eva Östlund, Marie Bixo

“…We estimated risk as adjusted odds ratio (aOR) with 95% confidence interval (CI), using individual‐level, linkage register‐data in multivariable logistic regression models. Results In the main analysis, MT was associated with a lower risk of neonatal hypoglycemia vs NT (aOR 0.85, 95% CI: 0.74–0.96), vs MIT (0.74 [0.64–0.87]), and vs IT (0.47 [0.40–0.55]), whereas MIT was associated with a similar risk of neonatal hypoglycemia vs NT (1.14 [0.99–1.30]) and with lower risk vs IT (0.63 [0.53–0.75]). …”
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Changes in global quality of life after treatment with immune checkpoint inhibitors in patients receiving different treatment regimens for advanced stage lung cancer in the Netherl... by Manuela Quaresma, Bernard Rachet, Geertruida H De Bock, Clémence Leyrat, Willemijn J Maas, Erick Suazo-Zepeda, Ananya Malhotra, Petra C Vinke, Jeroen T J.N Hiltermann

“…We aim to study the changes in global QoL (gQoL) of patients with advanced-stage lung cancer up to 18 months after treatment with ICIs between 2015 and 2021.Methods and analysis A longitudinal cohort study was conducted using the Oncological Life Study: Living well as a cancer survivor data-biobank from the University Medical Center Groningen. …”
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School-based Hygiene Intervention to Prevent HelicObacter Pylori infection among childrEn (SHIP HOPE): protocol for a cluster-randomised controlled trial by Jing Qi, Yang Guo, Mengge Zhou, Feng Cheng, Yuhong Zeng, Yu'e Xi, Sitong Luo, Guanqi Zhao, Yamei Sun

“…Therefore, in this study, we aimed to explore whether a comprehensive hygiene intervention can prevent H. pylori infection in primary schools in China.Methods and analysis The School-based Hygiene Intervention to Prevent HelicObacter Pylori infection among childrEn study is a cluster-randomised controlled trial, which will include approximately 2400 children in grades 2–4 from 60 classes in 10 primary schools of Linqu County, Shandong Province. …”
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Excessive occupational sitting increases risk of cardiovascular events among working individuals with type 1 diabetes in the prospective Finnish Diabetic Nephropathy Study by Matias Seppälä, Heidi Lukander, Johan Wadén, Marika I. Eriksson, Valma Harjutsalo, Per-Henrik Groop, Lena M. Thorn, FinnDiane Study Group

“…Our aim was to identify clinical factors associated with excessive occupational sitting in type 1 diabetes and, in a prospective setting, to explore its association with cardiovascular events and all-cause mortality, independent of leisure-time physical activity. Methods An observational follow-up study of 1,704 individuals (mean age 38.9 ± 10.1 years) from the Finnish Diabetic Nephropathy Study. …”
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A Personalized, Texting-Based Conversational Agent to Address Sleep Disturbance in Individuals Who Have Survived Breast Cancer: Protocol for a Pilot Waitlist Randomized Controlled... by Chi-shan Tsai, Warren Szewczyk, Michelle Drerup, Jason Liao, Alexi Vasbinder, Heather Greenlee, Jaimee L Heffner, Rachel Yung, Kerryn W Reding

“…Acceptability will be evaluated using a satisfaction survey and open-ended responses. Quantitative analysis, such as t test, Fisher exact tests, and generalized linear models, will be used to assess feasibility, baseline group differences, and the outcomes of the intervention. …”
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