Exploring the relationship between established HIV risk factors and depressive symptoms amongst young women without HIV in two sites in South Africa. by Zanenhlanhla Gumbi, Celia Mehou-Loko, Lindi Masson, Makhosazana Mdladla, Nokuthula Maphumulo, Jo-Ann Passmore, Sanele Mbeje, Linda Gail Bekker, Disebo Potloane, Heather Jaspan, Nina Radzey, Andrea Abrahams, Rushil Harryparsad, Pamela Mkhize, Hilton Humphries

“…Therefore, this study aims to determine the prevalence of depressive symptomology and explore the convergence of HIV risk factors with depressive symptoms amongst cis-gender adolescent girls and young women (AGYW) in rural KwaZulu-Natal (KZN) and peri-urban Western Cape (WC) communities in South Africa.<h4>Methods</h4>Cross-sectional survey data from two sites in South Africa was used - the rural Vulindlela community in KZN and the peri-urban Philippi East community in the WC. …”
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Excess mortality during and after the COVID-19 emergency in Japan: a two-stage interrupted time-series design by Shuhei Nomura, Masahiro Hashizume, Chris Fook Sheng Ng, Akifumi Eguchi, Ganan Devanathan, Paul LC Chua, Nasif Hossain

“…The study period extends beyond Japan ending the public health emergency.Methods Using national vital statistics data from 2015 to 2023, we employed a two-stage interrupted time series analysis to estimate excess mortality during the COVID-19 pandemic (2020–2023) compared with the prepandemic period (2015–2019). …”
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Nonlinear association between weekend sleep recovery (WSR) and insulin resistance: benefits in males and short weekday sleepers by Haidong Wang, Xiaohui Wei, Yudong Ba, Haiyan Liu, Yanhui Zhou, Weibo Wang, Lisheng Zheng

“…We used multivariable linear regression, stratified subgroup analyses (by sex, weekday sleep duration ≤7 vs >7 h, and different age groups), threshold effect modeling, and interaction analysis to assess associations. …”
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White-Matter Connectivity and General Movements in Infants with Perinatal Brain Injury by Ellen N. Sutter, Jose Guerrero-Gonzalez, Cameron P. Casey, Douglas C. Dean, Andrea de Abreu e Gouvea, Colleen Peyton, Ryan M. McAdams, Bernadette T. Gillick

“…Methods: Diffusion-weighted MRI data were analyzed in 17 infants, 12 with perinatal brain injury and 5 typically developing infants. …”
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Associations between Starting to Exercise in Later Life and Survival among Older Adults: a Nationwide, Community-based, Prospective Cohort Study in China by Haiyan Ruan, Ziqiong Wang, Kexin Wang, Muxin Zhang, Sen He

“…Accelerated failure time models were used to investigate the association between exercise duration and outcomes. …”
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Grade repetition and bullying victimization in adolescents: A global cross-sectional study of the Program for International Student Assessment (PISA) data from 2018. by Qiguo Lian, Chunyan Yu, Xiaowen Tu, Minglin Deng, Tongjie Wang, Qiru Su, Xiayun Zuo

“…This study aimed to investigate the global association of grade repetition with bullying victimization in a large-scale school-based cross-sectional study.<h4>Methods and findings</h4>We used the latest global data from the Program for International Student Assessment (PISA) 2018. …”
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Prognostic ability of the sTarT back screening tool for disability and pain intensity outcomes in older adults with low back pain seeking chiropractic care: a multi-national extern... by Yanyan Fu, Alan D. Jenks, Sidney M. Rubinstein, Katie de Luca, Iben Axen, Bart W. Koes, Alessandro Chiarotto

“…Therefore, our aim was to evaluate the ability of the SBT to predict three-, six-, and 12-month disability and pain outcomes in older adults (≥55 years) with a new episode of LBP consulting chiropractors in the Netherlands, Sweden, and Australia. Methods This was a secondary analysis of the Back Complaints in Older Adults – Chiropractic (BACE-C) cohort. …”
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Utilizing a modified-Postoperative Morbidity Survey for assessing morbidity after laparoscopic or robot-assisted radical prostatectomy: a retrospective observational study by Wenping Peng, Xiaolu Sun, Shuang Zhao, Huimin Hou, Jie Bao

“…The secondary objective was to investigate the correlation between m-POMS and postoperative LOS. Methods A retrospective study of the electronic health records was performed for all eligible patients undergoing laparoscopic or robot-assisted RP over a one-year period (August 1, 2022 to July 31, 2023). …”
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Development of a mafedine lyophilizate for parenteral use by O. A. Terenteva, V. A. Vainshtein, V. V. Tikhonova, A. K. Whaley, M. A. Trofimov, V. A. Prikhodko, L. V. Shigarova

“…The development of a dosage form of mafedine in order to improve its penetration into the central nervous system.Materials and methods. Mafedine (pharmaceutical substance) [6-oxo-1-phenyl-2-(phenylamino)-1,6-dihydropyrimidin-4-olate sodium] (St. …”
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CPT1A/HIF-1α positive feedback loop induced fatty acid oxidation metabolic pathway contributes to the L-ascorbic acid-driven angiogenesis in breast cancer by Xiao Ma, Baojian Zhang, Xuezhe Yin, ShiPeng Yang, Zhenhua Lin, Yang Yang, Xianchun Zhou

“…This research seeks to explore whether and how CPT1A, a crucial rate-limiting enzyme in fatty acid oxidation (FAO), supports angiogenesis through metabolic pathways in BC. Methods First, cell functional assays and animal models were employed to elucidate the pro-carcinogenic effects of CPT1A on BC and its role in metabolic alterations. …”
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Determinants of poor access to health care among women of reproductive age in Sierra Leone: a cross-sectional study by Augustus Osborne, Peter Bai James, Camilla Bangura

“…A mixed-effect multilevel binary logistic regression analysis was conducted, determining the factors associated with poor access to healthcare using a four-modeled approach. …”
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Biocompatibility and osteointegrative characteristics of zirconium ceramic implants for diaphyseal defect filling by Elena A. Volokitina, Maksim V. Saushkin, Irina P. Antropova, Sergey M. Kutepov, Svetlana A. Brilliant

“…The purpose of the work was to study the biological compatibility and osteointegrative characteristics of implants made of zirconium ceramics stabilized with yttrium, ytterbium and gadolinium for filling diaphyseal bone defects in an experiment. Material and methods The study was performed on 18 male Chinchilla rabbits. …”

Multidrug-resistant tuberculosis treatment outcomes and associated factors at Yirgalem General Hospital, Sidama Region, South Ethiopia: a retrospective cohort study by Assefa Hamato Kebede, Hassen Mamo

“…Bivariate and multivariable logistic regression models were used to identify factors associated with treatment outcomes for MDR-TB. …”
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SORBS3-β suppresses lymph node metastasis in cervical cancer by promoting the ubiquitination of β-catenin by Huating Sun, Yinghui Zhang, Fang Wang, Zizhao Wang, Yuhong Zhang, Youguo Chen, Li Wang, Jinhua Zhou

“…This study aimed to identify the functional isoform of SORBS3 driving LNM suppression and elucidate its mechanisms. Methods Proteomic analysis of clinical CC tissues and metastatic lymph nodes revealed progressive downregulation of SORBS3. …”
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Which Parameter Related to Low-Density Lipoprotein Cholesterol is Superior for Predicting the Recurrence of Myocardial Infarction in Young Patients with Previous Coronary Heart Dis... by Feng Xu, Hao-Ran Xing, Hong-Xia Yang, Jin-Wen Wang, Xian-Tao Song, Hui-Juan Zuo

“…The primary outcome was MI events, analyzed using survival analysis and logistic regression models to determine associations with LDL-C parameters. …”
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Decoding Survival in Elderly Acute Myocardial Infarction: The Prognostic Interplay of B-Type Natriuretic Peptide, Ejection Fraction, and Renal Function – An Observational Study by Rajpal Prajapati, Abhishek Kapoor, Salini Mukhopadhyay, Arjun Tandon, Soumik Ghosh, Om Shankar

“…This study evaluates the correlation between plasma BNP levels, LVEF, and estimated glomerular filtration rate (eGFR) and their prognostic significance in geriatric AMI patients managed conservatively. Materials and Methods: This prospective observational study was conducted at a tertiary care hospital in Northern India over 2 years (January 2022–December 2023). …”
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Direct and Indirect Effects of Risk Perception and Risk Information on PTSD in Frontline Healthcare Workers by Wu L, Geng S, Zhou Y, Jiao R, Ouyang H, Cheng S, Shang Z, Yan W, Wang J, Jia Y, Li X, Liu W

“…The PTSD checklist for DSM-5 (PCL-5), risk information questionnaire, and risk perception questionnaire are utilized to collect data.Methods: Bivariate correlation analysis and structural equation modelling are performed to analyze the mediating role of risk perception in the relationship between risk information and PTSD.Results: The estimated prevalence of PTSD among frontline healthcare workers is 28.2%. …”
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Efficacy and safety of radiotherapy combined with immunotherapy and targeted therapy versus immunotherapy plus targeted therapy alone in unresectable hepatocellular carcinoma: a re... by Yanling Yuan, Yongsheng Chen, Chumin Huang, Mindong Liu, Lihua Tong, Wubing Tang, Wen Yang

“…Outcomes were assessed using the modified Response Evaluation Criteria in Solid Tumors (mRECIST) criteria. Survival analysis was performed using Kaplan–Meier and Cox regression models.ResultsCompared with the IO+T group, the RT+IO+T group demonstrated superior short-term efficacy, as indicated by the objective response (69.0% vs. 35.7%, p=0.006) and disease control (89.7% vs. 57.1%, p=0.003) rates. …”
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Hypertension mediates the association between weight-adjusted waist index and new onset stroke risk in middle-aged and older Chinese adults: evidence from the CHARLS study by Fei Xu, Hongwei Liu, Meng Li, Minheng Zhang, Xuan Chen, Miaomiao Hou

“…However, the association between WWI and stroke risk across varying blood pressure statuses remains poorly understood.MethodsThis study included 12,580 individuals aged 45 and above with no prior stroke incidents, drawn from the China Health and Retirement Longitudinal Study (CHARLS) between 2011 and 2020. …”
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Factors influencing the kinetics of MSU crystal depletion measured with dual-energy CT in patients with gout by Tristan Pascart, Victor Laurent, Charlotte Jauffret, Aurore Pacaud, Vincent Ducoulombier, Julie Legrand, Stéphane Verdun, Laurène Norberciak, Jean-François Budzik

“…Objective To examine factors influencing the kinetics of monosodium urate (MSU) crystal dissolution measured with dual-energy computed tomography (DECT) during follow-up of patients with gout.Methods Patients with a diagnosis of gout with baseline knees and feet DECT scans exhibiting MSU crystal volumes ≥0.1 cm3 and at least one follow-up DECT were included. …”
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