Investigating amygdala nuclei volumes in military personnel with post-traumatic stress disorder, major depressive disorder, and adjustment disorder: A retrospective cross-sectional... by Thiemo Knaust, Dagmar Tarnogorski, Matthias B D Siebler, Philipp Skiberowski, Christian Moritz, Helge Höllmer, Holger Schulz

“…Amygdala subfields were automatically segmented and volumetrized using FreeSurfer software. Analysis of covariance (ANCOVA) models compared amygdala nuclei volumes across diagnostic groups, controlling for estimated total intracranial volume (eTIV), age, and gender. …”
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Real world data on characteristics and management of community patients receiving anticoagulation therapy who presented with acute bleeding to the emergency department at a regiona... by Fayez Hanna, Annemarie Hyppa, Ajay Prakash, Usira Vithanarachchi, Hizb U Dawar, Zar Sanga, George Olabode, Hamish Crisp, Alhossain A. Khalafallah

“…Data included: demographics, investigations (kidney and liver function tests, coagulation profile, FBC), LoS, bleeding site, type of and reason for anticoagulation therapy, and management provided. Data analysis included descriptive statistics, ?2 association, and regression models. …”
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Association of early acetaminophen administration with mortality in surgical intensive care patients: a retrospective cohort study by Jiajing Li, Yihao Li, Min Zhong, Hanli Chen, Ziyang Wang, Jianwei Wu, Yongyong Shi

“…This study aims to explore the relationship between early acetaminophen use and mortality in this patient population.MethodsWe conducted a retrospective cohort analysis of adult SICU patients using the Medical Information Mart for Intensive Care (MIMIC-IV) database, which contains data on patients admitted between 2008 and 2019. …”
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Prognostic value of HLA-I homozygosity in patients with non-small cell lung cancer treated with single agent immunotherapy by Mark Watson, Michael Millward, Samantha Bowyer, Afaf Abed, Leslie Calapre, Johnny Lo, Suzana Correia, Abha Chopra, Muhammad Adnan Khattak, Elin Solomonovna Gray

“…Background We aimed to assess the impact of genomic human leukocyte antigen (HLA)-I/II homozygosity on the survival benefit of patients with unresectable locally advanced, metastatic non-small lung cancer treated by single-agent programmed cell death protein-1/programmed death ligand 1 (PD1/PDL1) inhibitors.Methods We collected blood from 170 patients with advanced lung cancer treated with immunotherapy at two major oncology centers in Western Australia. …”
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At-Home Stroke Neurorehabilitation: Early Findings with the NeuroExo BCI System by Juan José González-España, Lianne Sánchez-Rodríguez, Maxine Annel Pacheco-Ramírez, Jeff Feng, Kathryn Nedley, Shuo-Hsiu Chang, Gerard E. Francisco, Jose L. Contreras-Vidal

“…This requires the high usability of the devices involved to minimize costs associated with support from physical therapists or technicians. Methods: This paper describes the early findings of the NeuroExo brain–machine interface (BMI) with an upper-limb robotic exoskeleton for stroke neurorehabilitation. …”
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Longitudinal associations between self-regulation and physical activity behavior following metabolic bariatric surgery; an exploratory study by C. Sundgot-Borgen, S. Baardstu, D. S. Bond, F. F. Sniehotta, I. Bergh, T. Mala, Ø. Rø, I. L. Kvalem

“…Second-order latent growth curve modeling examined changes in the three self-regulation constructs, followed by path analysis to explore direct, indirect, and bidirectional associations between baseline levels and changes in self-regulation, and MVPA at 1- and 5-years post-surgery. …”
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ICD-10 code-based definition of heart failure in Saint Petersburg electronic health records: prevalence, health care utilization and outcomes by A. E. Soloveva, G. V. Endubaeva, N. G. Avdonina, E. I. Kogan, T. V. Gorbacheva, A. V. Lubkovsky, A. N. Yazenok, A. N. Yakovlev, N. E. Zvartau, S. V. Villevalde, E. V. Shlyakhto

“…To analyze prevalence of heart failure (HF), clinical and demographic characteristics, health care utilization, and outcomes according to the used International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) codes in regional integrated electronic health record database in Saint Petersburg.Material and methods. The retrospective analysis of the Saint Petersburg regional integrated electronic health record database for 2019 was performed. …”
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A comparison of pediatric and adult ocular diseases in the context of social determinants of health by Deniz Oncel, Ria Ravi, Xhulio Arolli, Sandra Hoyek, Celine Chaaya, Audina M. Berrocal, Nimesh A. Patel

“…The prevalence of SoDH components were compared between pediatric and adult patients. Multivariable models were used for analysis. Results: The study population included 834,237 participants with 22,729 adult participants with ocular diseases and 6340 pediatric patients with ocular diseases. …”
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Machine Learning-Based Alfalfa Height Estimation Using Sentinel-2 Multispectral Imagery by Hazhir Bahrami, Karem Chokmani, Saeid Homayouni, Viacheslav I. Adamchuk, Rami Albasha, Md Saifuzzaman, Maxime Leduc

“…This study aimed to estimate alfalfa crop height through satellite images and machine learning methods within the Google Earth Engine (GEE) Python API. …”
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Nuclear Excitation of 181Ta Induced by High Power Femtosecond Laser Pulses by XU Yongsheng1, HE Chuangye1, LAN Xiaofei2, ZHAO Baozhen1

“…The findings contribute to a better understanding of the underlying physical mechanisms and highlight the potential for further optimization of experimental methods and theoretical models. Future studies are recommended to refine detection techniques and explore the influence of different plasma parameters on nuclear excitation yields. …”
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Observational study comparing the accuracy/variability between the ERSPC and the PCPT risk calculators for the prediction of significant prostate cancer in patients with PSA by Enrique Gomez Gomez, Juan José Salamanca Bustos, Julia Carrasco Valiente, Jose Luis Fernandez Rueda, Ana Blanca, José Valero Rosa, Ines Bravo Arrebola, Javier Marquez López, Juan Manuel Jimenez Vacas, Maria José Requena Tapia, Raul Miguel Luque

“…Discriminative ability for SigPCa was similar between models with an AUC=0.73 (0.68–0.79) for ERSPC-RC versus 0.73 (0.67–0.79) for PCPT-RC. …”
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Immune and Inflammation Markers as a Predictor of Overall Survival in Patients with Hematologic Malignancies: A Retrospective Cohort Study by Mehmet Ali Ucar, Anıl Tombak, Aydın Akdeniz, Hüseyin Derya Dinçyürek, Meryem Şener, Mahmut Bakır Koyuncu, Eyüp Naci Tiftik, Recep Dokuyucu

“…Overall survival was analyzed using Kaplan–Meier curves and Cox proportional hazards models, adjusted for age, sex, malignancy type, and disease stage. …”
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Mediating roles of preterm birth and restricted fetal growth in the relationship between maternal education and infant mortality: A Danish population-based cohort study. by Yongfu Yu, Zeyan Liew, Aolin Wang, Onyebuchi A Arah, Jialiang Li, Jørn Olsen, Sven Cnattingius, Guoyou Qin, Carsten Obel, Bo Fu, Jiong Li

“…We aimed to explore whether and the extent to which preterm birth (PTB) and small for gestational age (SGA) at birth mediate the association between maternal education and infant mortality.<h4>Methods and findings</h4>We developed a population-based cohort study to include all 1,994,618 live singletons born in Denmark in 1981-2015. …”
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<i>C11orf58</i> (Hero20) Gene Polymorphism: Contribution to Ischemic Stroke Risk and Interactions with Other Heat-Resistant Obscure Chaperones by Irina Shilenok, Ksenia Kobzeva, Vladislav Soldatov, Alexey Deykin, Olga Bushueva

“…<b>Background</b>: Recently identified Hero proteins, which possess chaperone-like functions, are promising candidates for research into atherosclerosis-related diseases, including ischemic stroke (IS). <b>Methods</b>: 2204 Russian subjects (917 IS patients and 1287 controls) were genotyped for fifteen common SNPs in Hero20 gene <i>C11orf58</i> using probe-based PCR and the MassArray-4 system. …”
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Osteopenic occult vertebral fracture is associated with poor oncological outcome in patients with hepatocellular carcinoma after hepatic resection by Koichiro Haruki, Kenei Furukawa, Munetoshi Akaoka, Masashi Tsunematsu, Michinori Matsumoto, Tomohiko Taniai, Yoshihiro Shirai, Shinji Onda, Ryoga Hamura, Toru Ikegami

“…Abstract Background Although osteopenia has been associated with poor outcomes in patients with hepatocellular carcinoma (HCC), the oncological impact of occult vertebral fracture (OVF) has not been investigated. Methods The study comprised 235 patients who had undergone primary hepatic resection for hepatocellular carcinoma between 2008 and 2019. …”
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Modified life’s essential 8 mediate the correlation between dietary index for gut microbiota and sleep disorders by Juanjuan Fang, Zhenhua Wang, Jiangshui Yu, Yumin Ye, Apang Du, Markus W. Ferrari

“…The specific relationship between DI-GM and sleep pathophysiology requires further elucidation. Methods: The data were obtained from the National Health and Nutrition Examination Survey (NHANES) across six cycles over the years 2007 to 2018. …”
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Big Data Analytics for Uncovering Voxel Connectivity Patterns in Attention Deficit Hyperactivity Disorder by Caraka RE, Supardi K, Gio PU, Isnaniawardhani V, Chen RC, Djatmiko B, Pardamean B

“…This study aims to apply advanced machine learning techniques to uncover critical features and improve classification performance in ADHD diagnosis.Methods: We analyzed 5937 brain voxels aggregated from neuroimaging records of patients diagnosed with ADHD. …”
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Protective role of coenzyme Q10 against trihexyphenidyl-induced pulmonary toxicity in Wistar rats by Joseph Gbenga Omole, Lydia Oluwatoyin Ajayi, Itunuoluwa Rachael Ajewole, Teniola Osholonge, Oyedayo Phillips Akano, Ayodeji Folorunsho Ajayi

“…This study investigated the protective effects of CoQ10 against THP-induced pulmonary toxicity in male Wistar rats. Methods Thirty-two adult male Wistar rats (180–200 g) were randomly assigned to four groups (n = 8 per group): (i) Control (vehicle-treated), (ii) THP (1.5 mg/kg), (iii) CoQ10 (10 mg/kg), and (iv) THP + CoQ10. …”
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Unveiling Theranostics: Nanocomplex-Assisted Photodynamic Eradication of Aggressive Cancer Cells and Modulation of Tumor-Associated Macrophages by Butkute A, Kazlauske E, Mlynska A, Peciukaityte E, Karabanovas V, Rotomskis R, Steponkiene S

“…Immunomodulatory effects were explored by exposing resident and recruited TAM models to a conditioned medium from PDT-treated CRC cells, followed by gene expression analysis.Results: Spectral characterization of the QDs-Ce6 nanocomplex demonstrated selective switching between diagnostic and therapeutic modes. …”
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A SORT1/EGFR molecular interplay as a prognostic biomarker in glioblastoma vasculogenic mimicry: implications in the transcriptional regulation of cancer stemness and drug resistan... by Marie-Eve Roy, Alain Zgheib, Nicoletta Eliopoulos, Borhane Annabi

“…This study questions whether the EGFR/SORT1 interplay impacts in vitro VM in human GBM-derived cell models. Methods In silico analysis was used to compare GBM to healthy brain tissue transcripts levels. cDNA arrays and RT-qPCR were performed to assess transcript levels in U87, U118, U138, and U251 GBM cells. …”
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