Development of a Nomogram for Prognostic Prediction of Large Hepatocellular Carcinoma With HBV After TACE Combined Conversion Therapy by Xu W, Ding X, Xu Y, Zhang Y, Xu H, Guo L, Li L

“…In the derivation cohort (n=201), the Cox regression analysis for developing nomograms for OS (time from initial TACE to death). …”
Get full text

Yin Yang 1 protein-activated N-acetyltransferase 10 drives cell malignant progression of osteosarcoma through ac4C acetylation of integrin β3 by Fan Yang, Mao Wang

“…This study endeavored to disclose the upstream and downstream mechanism of NAT10 related to Yin Yang 1 protein (YY1) and integrin β3 (ITGB3) in OS. Methods: Gene mRNA and protein levels were assayed via real-time quantitative PCR and Western blotting. …”
Get full text

The associations between serum carotenoids and hyperuricemia among U.S. National Health and Nutrition Examination Survey by Hong He, Ping Li, Haokun Huang, Yanlin Zeng, Min Zhang, Zhibing Chen, Shiqi Huang, Fangfang Zeng, Hui Ge

“…We aimed to investigate the association between serum carotenoid levels and hyperuricemia using data from the National Health and Nutrition Examination Survey (NHANES). Methods We conducted a cross-sectional analysis utilizing data from three specific NHANES cycles (2003–2004, 2005–2006, 2017–2018), containing the most complete serum carotenoid data from 12,253 participants aged 20 years and older. …”
Get full text

Adherence to the WCRF/AICR Cancer Prevention Recommendations and All-Cause Mortality among Cancer Survivors from the Moli-sani Study Cohort by Claudia Francisca Martinez, Augusto Di Castelnuovo, Simona Costanzo, Emilia Ruggiero, Giovanni de Gaetano, Licia Iacoviello, Marialaura Bonaccio

“…The aim of the present study was to assess whether compliance with the 2018 WCRF/AICR recommendations for cancer prevention is related to all-cause mortality among cancer survivors recruited in the Moli-sani Study cohort in Italy (2005–2010). Methods: A longitudinal analysis of 786 participants (59.7% women) with a history of cancer at study entry were analyzed. …”
Get full text

Universal screening for hyperglycemia in early pregnancy and the risk of adverse pregnancy outcomes by Lixia Shen, Shaofeng Zhang, Jiying Wen, Jia Liu, Xiaohong Lin, Caixia Zhu, Shiqin Cai, Lepei Xie, Zilian Wang, Haitian Chen

“…Abstract Introduction This study aimed to evaluate the screening outcomes in women with hyperglycemia in early pregnancy (fasting plasma glucose [FPG] 5.1–6.9 mmol/L and/or HbA1c 39–46 mmol/mol before 20 weeks of gestation). Methods This multicenter retrospective cohort study was conducted in China between 2016 and 2022. …”
Get full text

Association study between BGLAP RS1800247-polymorphic variant and type 2 diabetes mellitus development among hypertensive and non-hypertensive Ukrainians by Ya. D. Chumachenko, M. O. Kyrychenko, D. M. Ramazanova, M. V. Smiianova, V. Yu. Harbuzova, O. V. Ataman

“…To analyze the relation between rs1800247 SNP and T2DM occurrence depending on the arterial hypertension (AH) presence, as well as association between rs1800247 and systolic, diastolic, pulse, mean blood pressure among patients with T2DM. Materials and methods. This study included 153 patients with diagnosed T2DM and 311 individuals without any carbohydrate metabolism disorders. …”
Get full text

Flexural strength and surface hardness of nanocomposite denture base resins by Anagha Waghmare, Chandana Nair, Anuj K. Shukla, Mudita Chaturvedi, Tushar Vitthalrao Bhagat, Ebrahim Fihaid Alsubaiy, Ghazala Suleman, Mohasin Abdul Khader, Saurabh Chaturvedi

“…The processing and finishing of the models were done. Flexural strength was measured using a universal testing machine and surface hardness using a Rockwell hardness testing machine. …”
Get full text

Diabetes duration-specific association of dietary inflammatory index with the risk of mortality among individuals with diabetes by Xi Chen, Lixia Lin, Yuhe Tan, Ya Zhu, Wuxing Song, Hao Wang, Xufang Sun

“…Objective To investigate the association of the DII with all-cause mortality, cardiovascular disease (CVD) mortality, and cancer mortality among individuals with diabetes, and to explore whether diabetes duration could modify these associations. Methods A total of 9942 participants with diabetes from the UK Biobank were included. …”
Get full text

Assessment of all-cause and cardiovascular death risk in Russian men with leg pain by S. A. Shalnova, E. B. Yarovaya, V. A. Kutsenko, A. V. Kapustina, Yu. K. Makarova, Yu. A. Balanova, A. E. Imaeva, G. A. Muromtseva, O. M. Drapkina

“…To study the prevalence of intermittent claudication (IC) and assess the risk of cardiovascular and all-cause death In Russian men with IC according to 30-year follow-up.Material and methods. The study used data obtained from representative samples of men examined inMoscow andSt. …”
Get full text

Longitudinal history of mammographic breast density and breast cancer risk by familial risk, menopausal status, and initial mammographic density level in a high risk cohort: a nest... by Parisa Tehranifar, Erica J. Lee Argov, Shweta Athilat, Yuyan Liao, Ying Wei, Alexandra J. White, Katie M. O’Brien, Dale P. Sandler, Mary Beth Terry

“…However, the contribution of longitudinal changes in mammographic density to breast cancer risk beyond initial mammographic density levels, considering familial breast cancer risk and menopausal status, remains uncertain but holds important clinical implications. Methods In a nested case–control study within the Sister Study (323 cases, 899 controls; 12,095 mammograms), a cohort enriched for family history of breast cancer, we examined case–control status in relation to the largest annual change in percent density and dense area using mammograms available spanning 5.4 years, on average, using multivariable logistic regression and to the rate of mammographic density change using linear mixed-effects models. …”
Get full text

Plant-based diets and incident cardiovascular disease and all-cause mortality in African Americans: A cohort study. by Leah J Weston, Hyunju Kim, Sameera A Talegawkar, Katherine L Tucker, Adolfo Correa, Casey M Rebholz

“…Non-Hispanic black Americans are an understudied group with high burden of CVD, yet studies of plant-based diets have been limited in this population.<h4>Methods and findings</h4>We conducted an analysis of prospectively collected data from a community-based cohort of African American adults (n = 3,635) in the Jackson Heart Study (JHS) aged 21-95 years, living in the Jackson, Mississippi, metropolitan area, US, who were followed from 2000 to 2018. …”
Get full text

Personalized Support in Hereditary Breast and Ovarian Cancer After Genetic Counseling by the Chatbot-Based GENIE Mobile App: Proof-of-Concept Wizard of Oz Study by Dominik Wolff, Thomas Kupka, Chiara Reichert, Nils Ammon, Steffen Oeltze-Jafra, Beate Vajen

“…The content is presented through predefined dialogs between the user and the mobile assistant, aiming to extend the benefits of genetic counseling beyond the initial session. MethodsA Wizard of Oz study was conducted to evaluate a functional prototype of GENIE. …”
Get full text

Transforming nursing education: the power of educational leadership in optimizing time management and competency by Shaimaa Mohamed Amin, Ahmed Abdelwahab Ibrahim El-Sayed, Ahmed Abdellah Othman, Ahmed Salah Ali, Nagwa Ibrahim ELfeshawy, Hanan Hosni El-Sherbini, Abeer Abdel Fattah Mahmoud, Mohamed Hussein Ramadan Atta

“…Aim To investigate the mediating role of educational leadership in the relationship between time management and nursing competence among undergraduate nursing students. Methods A descriptive comparative cross-sectional study was conducted, involving a sample of 532 undergraduate nursing students selected using systematic random sampling. …”
Get full text

Temporal Trends of Maternal Mortality Due to Obstetric Hemorrhage in Chinese Mainland: Evidence from the Population-Based Surveillance Data Between 2000 and 2019 by Yi Mu, Jun Zhu, Yanping Wang, Jiani Zhang, Mingrong Li, Peiran Chen, Yanxia Xie, Juan Liang, Xiaodong Wang, Dandan Shi

“…Linear trends for changes in characteristics of maternal deaths were assessed using linear or logistic models with the year treated as a continuous variable. …”
Get full text

Real-World Effectiveness of Nirmatrelvir/Ritonavir in Hospitalized Older Adults with Severe Omicron COVID-19: A Retrospective Cohort Study from China by Chen Y, Liu L, Liu Y, Huang F, Guo L, Wan W, Jiang H

“…We aimed to estimate the effectiveness in older patients aged 80 and above with severe COVID-19.Methods: A retrospective study analyzed 263 COVID-19 patients aged 80 and above, admitted to the Department of Geriatrics at Jinling Hospital, affiliated with Nanjing University, between December 15, 2022, and January 15, 2023. …”
Get full text

High level of soluble tumor necrosis factor receptors is associated with lower residual diuresis volume in patients on hemodialysis: An exploratory study. by Gabriele Teixeira Gonçalves, Luciana Martins de Mello Santos, Pedro Henrique Scheidt Figueiredo, Jaqueline de Paula Chaves Freitas, Jousielle Márcia Santos, Joyce Noelly Vitor Santos, Fidelis Antônio da Silva Junior, Frederico Lopes Alves, Vanessa Gomes Brandão, Emílio Henrique Barroso Maciel, Maria Cecília S M Prates, Borja Sañudo, Redha Taiar, Mario Bernardo-Filho, Danúbia da Cunha de Sá-Caputo, Vanessa Pereira Lima, Henrique Silveira, Victor Lacerda Gripp, Vanessa Amaral Mendonça, Ana Cristina Rodrigues Lacerda

“…This study aimed to explore the possible relationship between inflammatory parameters and residual diuresis volume in patients on hemodialysis.<h4>Methods</h4>Blood samples were collected from patients on hemodialysis for the analysis of soluble receptors: 1) tumor necrosis factor receptor 1 (sTNFR1), 2) tumor necrosis factor receptor 2 (sTNFR2), and 3) leptin. …”
Get full text

Are there benefits of low doses of ACE inhibitors, MRAs, diuretics and statins in the treatment of heart failure? by V. А. Lysenko

“…Risk factors were determined, and prognostic uni- and multi-variant Cox proportional hazards regression models were used. The cut-off values of quantitative risk factors were obtained by ROC analysis. …”
Get full text

Bile acid metabolism in multiple sclerosis is perturbed and associated with the risk of confirmed disability worsening by Ida Erngren, Aina Vaivade, Henrik Carlsson, Asma Al-Grety, Torbjörn Åkerfeldt, Ingrid Kockum, Anna Karin Hedström, Lars Alfredsson, Tomas Olsson, Joachim Burman, Kim Kultima

“…This study aimed to examine serum BA levels in newly diagnosed people with MS (pwMS) and explore their association with disability worsening. Methods The study included 907 pwMS and 907 matched controls from the Swedish population-based EIMS cohort, with clinical follow-up data from the Swedish MS Registry. …”
Get full text

Orthodontic Treatment Stability Evaluation with Two Different Ligation Bracket Systems: An Ambispective Cohort Study by Manjiri Bhate, Ravindra Kumar Jain

“…Aim: To evaluate and compare the two-year post-treatment stability of orthodontic treatment using conventional brackets versus passive self-ligating brackets. Materials and Methods: An ambispective cohort study was conducted in the Department of Orthodontics at Saveetha Dental Hospitals, Chennai, Tamil Nadu, India from January 2024 to March 2024. …”
Get full text

The magnitude of casual sex and associated factors among students at Debre Berhan University by Tsega Mathewos, Esubalew Tesfahun, Muluken Tessema Aemiro, Tadesse Mamo Dejene

“…However, there has been limited research on the prevalence of casual sex and related issues in higher education institutions in Ethiopia.ObjectiveTo assess the prevalence of casual sex and its associated factors among regular undergraduate students at Debre Berhan University in 2023.MethodsFrom 15 May 2023, to 30 May 2023, regular undergraduate students from Debre Berhan University participated in a cross-sectional study. …”
Get full text