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68721
Exploring the relationship between dietary patterns and health-related quality of life among Iranian adult population: Tehran lipid and glucose study
Published 2025-06-01“…Dietary patterns were identified using factor analysis. General linear models were used to assess the association between dietary patterns and HRQoL scores. …”
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68722
Visual Acuity Outcomes and Influencing Factors in a Cohort of UK Real-World Diabetic Macular Oedema Patients During the First Two Years of Anti-VEGF Treatment
Published 2025-01-01“…Descriptive analysis examined baseline demographics and clinical characteristics, while regression models were used to assess associations between these factors and changes in VA. …”
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68723
Thirteen-Year Sequelae of Marburg Virus Disease Survival: Persistent Cardiometabolic, Immunometabolic, and Haematological Alterations in the Absence of Psychological Morbidity
Published 2025-07-01“…We present one of the most temporally distant evaluations of MVD survivors, conducted 13 years post-outbreak in Uganda, offering novel insights into chronic physiological, biochemical, haematological, and psychosocial outcomes. <b>Methods</b>: A cross-sectional, community-based study compared ten MVD survivors with nineteen age- and sex-matched unexposed controls. …”
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68724
METTL3 promotes an immunosuppressive microenvironment in bladder cancer via m6A-dependent CXCL5/CCL5 regulation
Published 2025-04-01“…This study investigates the role of METTL3, an m6A RNA methylation “writer,” in regulating the immune microenvironment of BLCA.Methods Through bioinformatics analysis, we identified METTL3 as being associated with the formation of an immunosuppressive microenvironment in BLCA and poor response to immunotherapy. …”
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68725
Indoor solid fuel use for cooking and the risk of incidental non-fatal cardiovascular disease among middle-aged and elderly Chinese adults: a prospective cohort study
Published 2022-05-01“…Under these circumstances, this study examined the association between solid fuel use and incidental non-fatal CVD.Design The prospective cohort study was conducted in 2011, 2013, 2015 and 2018.Setting The nationally representative survey was conducted in 28 provinces of China.Participants This study included 13 544 middle-aged and elderly adults without CVD in the baseline survey, and they were followed for 7 years.Outcome measures First incidence of non-fatal CVD (heart disease or stroke).Methods Based on longitudinal data, Cox proportional hazards models were used to assess the effects of solid fuel use and persistent use on incidental CVD events.Results During the 7-year follow-up period, there were 1533 non-fatal CVD cases. …”
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68726
The Consolidated Framework for Implementation Research (CFIR) User Guide: a five-step guide for conducting implementation research using the framework
Published 2025-08-01“…Abstract Background The Consolidated Framework for Implementation Research (CFIR) is a determinant framework that includes constructs from many implementation theories, models, and frameworks; it is used to predict or explain barriers and facilitators to implementation success. …”
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68727
Estimating the global and regional burden of lower respiratory infections attributable to leading pathogens and the protective effectiveness of immunization programs
Published 2024-12-01“…Our objective was to assess the global burden of LRIs attributable to S. pneumoniae, H. influenzae, and influenza virus and explore the protective effectiveness of immunization programs. Methods: Data were retrieved from the Global Burden of Disease Study 2021 and World Health Organization United Nations Children's Fund Estimates of National Immunization Coverage. …”
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68728
Fear of hypoglycemia: a key predictor of sleep quality among the diabetic population
Published 2025-04-01“…We hypothesize that FOH is a key predictor of sleep quality in Type-I and Type-II patients with diabetes and, therefore, needs detailed investigation.MethodsA multicentric study was conducted across five cities and six centers of Punjab. …”
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68729
Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis
Published 2025-03-01“…However, the role of sialylated IgG in colorectal cancer liver metastasis remains undefined. Materials and methods: Analysis of sialylated IgG in paired tumor tissues and adjacent normal tissues from 65 colorectal cancer patients was performed using immunohistochemical staining. …”
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68730
Advancing student outcome predictions through generative adversarial networks
Published 2024-12-01“…The effectiveness of these predictive models relies on having access to sufficient and accurate data. …”
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68731
The effect of bullying victimization on internet addiction: mediated by cyberbullying perpetration and moderated by social support
Published 2025-08-01“…General linear modeling (GLM), structural equation modeling (SEM), and interaction item analysis were conducted. …”
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68732
Mineral resource base of Russia’s cobalt: current state and development prospects
Published 2025-06-01“…Objective: to examine the current state of Russia’s cobalt mineral resource base, the spatial distribution of cobalt deposits by ore formation types and within ore provinces, and the prospects for national cobalt production. Methods: statistical, graphical, and logical analysis. …”
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68733
Duration of frontline therapy and impact on clinical outcomes in newly diagnosed multiple myeloma patients not receiving frontline stem cell transplant
Published 2023-02-01“…This retrospective study of NDMM patients evaluated the relationship between dose‐attenuation of 1LT and duration of therapy (DOT) and DOT on outcomes. Methods Adults with NDMM not undergoing stem cell transplant (SCT) from January 1, 2012 toMarch 31, 2018 from the Integrated Oncology Network were included; 300 were randomly selected for chart review. 1LT DOT, time to next treatment (TTNT), progression‐free survival (PFS), and overall survival (OS) were estimated using Kaplan–Meier analysis. …”
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68734
Cost-effectiveness of massed versus spaced trauma-focused treatment as first-line treatment for post-traumatic stress disorder in adults with multiple trauma exposure: protocol for...
Published 2025-05-01“…This paper describes the research protocol of a single-blind, multicentre randomised controlled trial (RCT) aimed at investigating: (1) the clinical and cost-effectiveness of M-TFT versus S-TFT in employed, multiply traumatised patients who seek first-line treatment for PTSD and (2) predictive and moderating factors related to treatment response.Methods and analysis 186 participants are recruited from five centres and will be included if they are ≥18 years old, meet criteria for a Diagnostic and Statistical Manual of Mental Disorders Fifth Edition PTSD diagnosis based on ≥two PTEs, seek treatment for the first time and are employed. …”
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68735
Comparison of the Predictive Value of Neutrophil Percentage-to-Albumin Ratio and Modified Glasgow Prognostic Score for the Risk of Stroke-Associated Pneumonia Among Stroke Patients
Published 2025-03-01“…Univariate and multivariate logistic regression models were employed to explore the association between NPAR, mGPS and SAP occurrence among individuals with stroke. …”
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68736
Alexithymia and self-injury functions as mediators between childhood maltreatment and nonsuicidal self-injury in adolescents with major depressive disorder
Published 2025-07-01“…Structural equation modeling (SEM) was employed to evaluate the direct effect of CM on NSSI, as well as the mediating effects of alexithymia and SF. …”
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68737
Health diagnosis associated with COVID-19 death in the United States: A retrospective cohort study using electronic health records.
Published 2025-01-01“…<h4>Objective</h4>To identify demographic factors and health diagnosis codes that pose a high or a low risk to COVID-19 death from individual health record data sourced from the United States.<h4>Methods</h4>We used logistic regression models to analyze the top 500 health diagnosis codes and demographics that have been identified as being associated with COVID-19 death.…”
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68738
Association of the “life’s crucial 9” cardiovascular health with all-cause and cardiovascular disease mortality: a national cohort study
Published 2025-04-01“…Weighted Cox proportional hazards regression models and restricted cubic spline analysis were applied to evaluate the association of LC9 with mortality. …”
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68739
Weight Gain, Weight Loss, and Type 2 Diabetes Risk: Evidence From the Atherosclerosis Risk in Communities (ARIC) Study
Published 2025-05-01“…Therefore, we aimed to assess the impact of 3‐year weight change on incident T2DM over 6 years among US individuals. Methods A total of 8377 participants aged 45–64 years (4601 women), free of T2DM or cancer at baseline from the Atherosclerosis Risk in Communities (ARIC) study were included. …”
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68740
Efficacy of multiple autologous apheresis platelet-rich plasma injections for treating knee osteoarthritis and its influencing factors: a retrospective cohort study
Published 2025-04-01“…The Mann-Whitney U test, Kruskal–Wallis H test, Spearman correlation analysis, and restricted cubic spline models were used to assess the associations between sex, baseline Kellgren–Lawrence grade, age, PRP red blood cell (RBC) concentration, PRP white blood cell (WBC) concentration, PRP platelet concentration, the multiple of PRP platelet concentration relative to the baseline autologous level (Enrichment-PLT), and self-reported recovery rates. …”
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