Association between maternal smoking during pregnancy and smoking behaviors in adult offspring by Lin Yang, Jing Li, Jing Li, Yinzi Chen, Yanling Wei, Congying Song, Jingwen Zhang, Liang Dai, Yu Shi, Zuying Xiong, Ying Shan, Xiaoyan Huang, Xiaoyan Huang

“…However, there is still scant evidence to support the association between MSP and smoking behaviors in adult offspring.MethodsThis is a prospective cohort study based on the UK Biobank. …”
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Efficacy of the Foodbot Factory digital curriculum-based nutrition education intervention in improving children’s nutrition knowledge, attitudes and behaviours in elementary school... by Wendy Lou, Michael Farkouh, JoAnne Arcand, Jacqueline Marie Brown, Saman Tahir, Beatriz Franco-Arellano, Ann LeSage, Janette Hughes, Bill Kapralos, Ellen Vogel, Claire Tugault-Lafleur

“…Pilot data have demonstrated that Foodbot Factory can significantly improve children’s nutrition knowledge, but it has not yet been evaluated in classrooms.Methods and analysis A single-blinded cluster randomised controlled trial was designed in 2022 by a research team based at Ontario Tech University to determine the efficacy of the Foodbot Factory intervention in improving children’s nutrition knowledge, attitudes and behaviours. 32 grade 4 and 4/5 classrooms in Ontario will be randomised to receive (1) the Foodbot Factory intervention or (2) a control nutrition education intervention using conventional materials (eg, activity sheets). …”
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C.E. Credit. Effect of Steam Sterilization on Accuracy of 3D Printed Implant Surgical Guides: A Pilot Study by Daniel Rexin, Daniela Avila, Alexander Castillo, Kevin Moreno, Emily Tan, Sunee Limmeechokchai, Joseph Lee, Udochukwu Oyoyo, So Ran Kwon, Joseph Y. Kan, Jaime L. Lozada, Robert A. Handysides, Ahmad Alkanderi

“…This study evaluated the effect that steam sterilizing 3D printed implant surgical guides has on the accuracy of fully guided implant placement.Methods 3D printed models were prepared with an edentulous site at the right maxillary central incisor. …”
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AI-driven discovery of minimal sepsis biomarkers for disease detection and progression: precision medicine across diverse populations by Qiyuan Su, Jingtao Huang, Yunlong Zhang, Zhou Liu, Zhihua Lv, Chunming Zhang, Chengxiu Ling, Hanwen Su, Liying Zhan, Zhengjun Zhang, Zhengjun Zhang, Zhengjun Zhang

“…BackgroundSepsis biomarker research over the past 30 years has been plagued by the use of wrong animal models and inappropriate patient selections, leading to the failure of translating findings into precision medicine. …”
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Associations of frailty and cognitive impairment with all-cause and cardiovascular mortality in older adults: a prospective cohort study from NHANES 2011–2014 by An-Bang Liu, Yan-Xia Lin, Guan-Ying Li, Ting-Ting Meng, Peng Tian, Jian-Lin Chen, Xin-He Zhang, Wei-Hong Xu, Yu Zhang, Dan Zhang, Yan Zheng

“…This study aims to explore how frailty and psychometric mild cognitive impairment (pMCI) jointly affect all-cause and cardiovascular disease (CVD) mortality. Methods The cohort study we examined 2,442 participants aged ≥ 60, is the secondary analysis from the National Health and Nutrition Examination Survey (NHANES) 2011–2014. …”
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Reduced sensitivity to thyroid hormones is associated with differentiated thyroid cancer in the euthyroid thyroidectomy population by Huaijin Xu, Huaijin Xu, Hongzhou Liu, Xiaodong Hu, Xiaomeng Jia, Zhe Xue, Anning Wang, Shaoyang Kang, Shaoyang Kang, Zhaohui Lyu, Zhaohui Lyu

“…The association of DTC with TT4RI or TSHI was stronger than with other thyroid parameters such as TSH (thyroid stimulating hormone). ROC analysis for the distinction between DTC and benign disease showed no single thyroid parameter with the coexistence of high sensitivity and specificity.ConclusionReduced central and peripheral sensitivity to thyroid hormones is associated with DTC in the euthyroid thyroidectomy population and provides additional information on the odds of malignancy in thyroid nodules at risk for surgery, warranting consideration of the role of sensitivity to thyroid hormones in mechanisms and prediction models for DTC.…”
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Healthy Cardiovascular Status Attenuates the Detrimental Association Between Osteosarcopenic Adiposity and Alzheimer's Disease‐Related Dementia: A UK Biobank Cohort Study by Wenxu Wang, Rui Ren, Honghao Yang, Jinguo Jiang, Xingyue Ye, Chenying Wang, Xiang Ji, Wen Li, Yuhong Zhao, Yang Xia, Difei Wang

“…The hazard ratios (HRs) and 95% CIs for ADRD were estimated using Cox proportional hazards models. A secondary analysis included 14 750 participants with brain magnetic resonance imaging data to explore the role of brain structure in the association between OSA and the incidence of ADRD. …”
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Improvement of Saline–Alkali Soil and Straw Degradation Efficiency in Cold and Arid Areas Using <i>Klebsiella</i> sp. and <i>Pseudomonas</i> sp. by Xiaoyu Zhao, Xiaofang Yu, Julin Gao, Jiawei Qu, Qinggeer Borjigin, Tiantian Meng, Dongbo Li

“…Microbial characteristics, straw degradation efficiency, element release rate, and soil factors were compared, and random forest linear regression and partial least squares path modeling analysis methods were utilized. The results indicated that the degradation of bacterial metabolites, the efficiency of corn stover degradation, the efficiency of component degradation, and the release rates of elements (C, N, P, and K) initially increased and then decreased with the increase in salinity. …”
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Smart Fault Detection, Classification, and Localization in Distribution Networks: AI-Driven Approaches and Emerging Technologies by Jianxian Wang, Hazlie Mokhlis, Nurulafiqah Nadzirah Mansor, Hazlee Azil Illias, Agileswari K. Ramasamy, Xingyu Wu, Siqi Wang

“…Following the chronological development of artificial intelligence, the review systematically investigates smart fault detection methods applied to fault scenarios in distribution networks, with a particular emphasis on presenting fault type classification and fault localization separately to facilitate a logically structured understanding. …”
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The association between anthocyanin intake and myopia in adolescents: a cross-sectional study of NHANES by Ying Chen, Ying Chen, Ying Chen, Qinglin Xu, Qinglin Xu, Lu Lv, Lu Lv, Yun Liu, Yun Liu, Zhidan Zhang, Zhidan Zhang, Zhikuan Yang

“…The relationships between anthocyanin and subtypes intake and myopia were determined utilizing weighted univariate and multivariate logistic regression models. The relationships were also explored in gender, leisure time, physical activity, sedentary activity, BMI, and serum cotinine subgroups.ResultsA total of 839 adolescents were included for further analysis, among them 245 have myopia. …”
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Ambulatory cancer care electronic symptom self-reporting (ACCESS) for surgical patients: a randomised controlled trial protocol by Andrea L Pusic, Daniel Stein, Cara Stabile, Larissa K Temple, Jessica S Ancker, Ethan Basch, Jeanne Carter, Magen Miranda, Peter D Stetson, Andrew Vickers, Brett A Simon

“…Despite abundant evidence that patient self-reporting of symptoms improves quality of care, the most effective way to monitor and manage this self-reported information is not known.Methods and analysis This is a two-armed randomised, controlled trial evaluating two approaches to the management of patient-reported data: (1) team monitoring, symptom monitoring by the clinical team, with nursing outreach if symptoms exceed normal limits, and (2) enhanced feedback, real-time feedback to patients about expected symptom severity, with patient-activated care as needed.Patients with breast, gynaecologic, urologic, and head and neck cancer undergoing ambulatory cancer surgery (n=2750) complete an electronic survey for up to 30 days after surgery that includes items from a validated instrument developed by the National Cancer Institute, the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE). …”
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The cognitive cerebellum: linking microstructure to cognitive functions in a healthy population by Nicole Urbini, Carolyn B. McNabb, Derek K. Jones, Craig Hedge, Eirini Messaritaki, Pedro Luque Laguna, Mara Cercignani

“…Methods: Using a large normative cohort, the study examined cerebellar GM and WM volumes in 151 participants and FA in 83 participants. …”
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Cardiovascular Risk in Patients With Treated Isolated Diastolic Hypertension and Isolated Low Diastolic Blood Pressure by Wei‐Lun Chang, Ying‐Fan Chen, Yu‐Hsuan Lee, Ming‐Neng Shiu, Po‐Yin Chang, Chao‐Yu Guo, Chi‐Jung Huang, Chern‐En Chiang, Chen‐Huan Chen, Shao‐Yuan Chuang, Hao‐Min Cheng

“…MACE risk was estimated using Cox proportional‐hazards models. Among the SPRINT participants, median age was 67.0 years and 64.9% were men. …”
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BDNF expression mediates verbal learning and memory in women in a cohort enriched with risk for Alzheimer's disease by Kyle J. Edmunds, Alyssa A. Pandos, Isabella Hoang, Gabriella M. Mamlouk, Alice Motovylyak, Sarah R. Lose, Sanjay Asthana, Matthew Stremlau, Sterling C. Johnson, Henriette vanPraag, Ozioma C. Okonkwo

“…Plasma BDNF was measured using a Human BDNF Quantikine Immunoassay. Mediation analysis used bootstrapping, and stratified mediation models tested the conditional dependence of APOE ε4 carriage. …”
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PYGO1 drives gastric cancer progression via the ITGB1/CD47 axis and is therapeutically targeted by pentagalloylglucose by Yanjuan Jia, Yaling Li, Yan Li, Yonghong Li, Tao Qu, Zhuomin Fu, Yuanyuan Ma, Zhenhao Li, Wanxia Wang, Miao Yu, Xiaojie Jin, Xiaoling Gao, Yongqi Liu

“…This study aims to elucidate the role of PYGO1 in GC and uncover its regulatory mechanisms. Methods Bioinformatics analysis and immunohistochemistry were used to assess PYGO1 expression in GC tissues and its correlation with prognosis and immune cell infiltration. …”
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Gaps in health coverage for racialized im/migrant sex workers in metro Vancouver: Findings of a community-based cohort study (2014–2021) by Shira M. Goldenberg, Maggie Hamel-Smith Grassby, Alaina Ge, Melissa Braschel, Charlie Zhou, Kate Shannon

“…We examined associations between im/migration status, duration, and racialization on gaps in health insurance coverage in a cohort of women sex workers. Methods: Analyses used data from a prospective, community-based cohort of women sex workers in Vancouver, BC (Sept 2014-August 2021). …”
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Effectiveness of a standardised and interactive intervention to prevent preschooler unintentional injury in rural China: a cluster randomised controlled trial by Jie Li, Guoqing Hu, David C Schwebel, Min Zhao, Peishan Ning, Wanhui Wang, Jieyi He, Weiqiang Li

“…This study evaluated the effectiveness of a standardised school-based interactive education intervention to prevent unintentional injury for rural preschoolers.Methods A 9-month single-blinded cluster randomised controlled trial was conducted in rural China, involving 12 preschools with 2518 preschoolers aged 3–6 years old. …”
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The Australian and New Zealand Fontan Registry Quality of Life Study: Protocol for a population-based assessment of quality of life among people with a Fontan circulation, their pa... by Daniel S J Costa, Kim Dalziel, Yves d’Udekem, David S Winlaw, David S Celermajer, Nadine A Kasparian, Diana Zannino, Rachel Bishop, Kate H Marshall, Susan R Woolfenden, Gary F Sholler

“…The objective of this study is to describe and develop a deeper understanding of the factors that contribute to quality of life (QOL) among children, adolescents and adults living with a Fontan circulation across Australia and New Zealand, their parents and siblings.Methods and Analysis This article presents the protocol for the Australian and New Zealand Fontan Registry (ANZFR) QOL Study, a cross-sectional, population-based study designed to examine QOL among people of all ages with a Fontan circulation, their parents and siblings. …”
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Risk factors and outcomes in patients who switched from peritoneal dialysis to physician-oriented or patient-oriented kidney replacement therapy by Liu Zhang, Xu Guan, Liang Liu, Yinghui Huang, Jiachuan Xiong, Jinghong Zhao

“…Background We aimed to compare the cardiovascular events and mortality in patients who underwent either physician-oriented or patient-oriented kidney replacement therapy (KRT) conversion due to discontinuation of peritoneal dialysis (PD).Methods Patients with end-stage kidney disease who were receiving PD and required a switch to an alternative KRT were included. …”
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Renal function and clinical outcomes in survivors of out-of-hospital cardiac arrest by Hao-Wei Lee, Ming-Jen Kuo, Pai-Feng Hsu, I-Hsin Lee, Chih-Yu Yang, Teh-Fu Hsu, Chorng-Kuang How, Yenn-Jiang Lin, Chin-Chou Huang

“…Among patients without ESRD, 82.5% developed AKI, of which 31.0% achieved AKI recovery, while 61.0% were discharged with impaired renal function. Multivariable analysis using regression models revealed that unfavorable neurological outcomes at discharge and higher mortality at 2 years were associated with AKI (odds ratio [OR] 7.684, 95% confidence interval (CI) 2.683–22.010, P < 0.001; hazard ratio [HR] 2.159, 95% CI 1.272–3.664, P = 0.004), AKI without recovery (OR 5.275, 95% CI 2.049–13.583, P < 0.001; HR 5.470, 95% CI 3.304–9.862, P < 0.001), and impaired pre-discharge renal function (OR 3.164, 95% CI 1.442–6.940, P = 0.004; HR 2.876, 95% CI 1.861–4.443, P < 0.001). …”
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