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841
Patient reported outcomes in the FDA approved drugs for systemic rheumatic diseases (2013–2024)
Published 2025-05-01“…Objective This study aims to systematically characterize the use of PROs in pivotal trials supporting the US Food and Drug Administration (FDA) approval of SRDs treatments and to assess the quality of reporting. Methods We reviewed the pivotal trials supporting the approval of SRD indications by FDA since July 2013 to assess the use of PROs, including specific PRO measures (PROMs) and types of endpoints designated. …”
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842
Comparative Evaluation of Various ABO<sub>3</sub> Perovskites (A = La, Ca, Sr; B = Mn, Fe) as Oxygen Carrier Materials in Chemical Looping Hydrogen Production
Published 2025-04-01“…Perovskites such as (La<sub>1−x</sub>Ca<sub>x</sub>)MnO<sub>3</sub>, (La<sub>1−x</sub>Sr<sub>x</sub>)MnO<sub>3</sub>, and (La<sub>0.6</sub>Ca<sub>0.4</sub>)(Mn<sub>1−x</sub>Fe<sub>x</sub>)O<sub>3</sub> were synthesized via wet chemical methods and tested in chemical looping cycles. Doping A-site cations with Ca or Sr enhanced oxygen delivery capacity by more than 100% upon reduction with CH<sub>4</sub> when dopant content (x) increased from 0 to 0.5. …”
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843
Structural, magnetic, and optical characteristics of undoped and chromium, iron, cobalt, copper, and zinc doped nickel oxide nanopowders
Published 2025-01-01“…In this regard, the preparation of pristine NiO and Ni0.95 × 0.05O (X = Cr, Fe, Co, Cu, and Zn) powders was successfully achieved through the co-precipitation method. The X-ray powder diffraction was employed to examine the prepared powders’ phase formation and crystal structure characteristics. …”
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844
Experimental and Reliability Analysis of Flexural Performance of CFRP Strengthened Damaged Reinforced Concrete Beams
Published 2025-01-01“…Key factors influencing the bending load capacity of these damaged concrete beams include the height coefficient of the compression zone, steel reinforcement ratio, utilization factor of carbon fiber cloth strength, and failure modes. A calculation method is proposed for determining the bending load capacity of cracked damaged RC beams after unloading with carbon fiber cloth reinforcement; this method demonstrates high accuracy. …”
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845
Building of CuO<sub>2</sub>@Cu-TA@DSF/DHA Nanoparticle Targets MAPK Pathway to Achieve Synergetic Chemotherapy and Chemodynamic for Pancreatic Cancer Cells
Published 2024-12-01“…Meanwhile, utilizing the Fenton-like effect induced by the multi-copper mode can achieve ROS storm, activate the MAPK pathway, and achieve chemotherapy (CT) and chemodynamic (CDT). …”
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846
Cardio-renal protective effect and safety of sodium-glucose cotransporter 2 inhibitors for chronic kidney disease patients with eGFR < 60 mL/min/1.73 m2: a systematic review and me...
Published 2024-11-01“…Abstract Objective This meta-analysis was designed to investigate cardio-renal outcomes and safety of sodium-glucose cotransporter-2 inhibitors (SGLT2i) as a therapeutic option among chronic kidney disease(CKD) patients with GFR < 60 mL/min/1.73 m2, regardless of their diabetic status. Method We conducted a full-scale search from MEDLINE, EMBASE and the Cochrane Library database to identify eligible studies up to Jun 2024. …”
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847
Investigating the adsorption of acid blue 90 onto porous MIL53(Fe) and Cu-BTC sorbents: An examination of process parameters, isotherm modelling, and kinetic studies
Published 2025-09-01“…Batch mode experiments were conducted for the optimization of acid bleu 90 adsorption. …”
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848
The ideals of student youth in relation to the present, possible and anti-ideal
Published 2022-04-01“…The aim of the current research is to study the ideals of student youth in the context of the desired/present, possible/impossible, and permissible/unacceptable (anti-ideal).Methodology and research methods. The object of research is images of “other people” with socio-group and characteristic features, freely reproduced by students. …”
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849
Progress and prospect of surface self-cleaning technology of machine vision system in underground mining
Published 2025-06-01“…Aiming at the scientific problems of multi-technology collaboration and cleaning quality control, a far-near-field collaborative control method is proposed, which can provide relevant technical support for the surface self-cleaning technology of the underground mining machine vision system. …”
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850
Exploring the therapeutic potential of propolis in managing diabetes: A preclinical study
Published 2025-04-01“…Objective: To evaluate the therapeutic potential and underlying mechanisms of action of propolis in db/db mice. Methods: The chemical composition of propolis was analyzed using UHPLC-MS/MS. …”
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851
Structural myocardial changes in chronic heart failure of II functional class based on overweight and abdominal obesity
Published 2014-04-01“…Research objective: to establish the structural changes of CHF of II functional class depending on the availability of overweight and abdominal type of obesity various degrees. Material and methods: 153 patients with CHF of II functional class were examined. …”
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852
The Impact of Additive and Subtractive Manufacturing on the Adhesion and Durability of Titanium–Zirconia Restorative Materials
Published 2025-07-01“…The density, microhardness, and surface morphology were evaluated, along with the shear bond strength and failure modes of the resin composites. Statistical differences were analyzed using one-way ANOVA and Tukey’s HSD test across all groups. …”
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853
Thermodynamic properties of L-menthol in crystalline and gaseous states
Published 2020-03-01“…Electronic energy and frequencies of normal modes of the molecules involved in these reactions were calculated using the Gaussian 4 composite quantum chemical method. …”
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854
Total and Structural Carotid Artery Stiffness Are Associated With Cognitive Decline and Structural Brain Abnormalities Related to Alzheimer Disease and Alzheimer Disease‐Related De...
Published 2025-05-01“…Total pulse wave velocity can be subdivided into 2 main mechanisms: structural arterial stiffness (S‐PWV) due to intrinsic remodeling of the artery wall and load‐dependent arterial stiffness due to increased blood pressure. Methods and Results In this prospective cohort study, MESA (Multi‐Ethnic Study of Atherosclerosis) participants completed B‐mode carotid ultrasounds from which carotid total pulse wave velocity was calculated. …”
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855
Design and analysis of spiral plating solution flow and rotating magnetic field device for electroplated diamond wire saw
Published 2025-04-01“…The research focuses on solving three core problems: (1) the structural design of the spiral bath flow electroplating device and the optimization of flow rate and spiral speed of the spiral bath flow; (2) the structural design of the rotating magnetic field device and the optimization of rotation speed and magnetic field strength; (3) the optimal process parameters for electroplating diamond wire saws in the new composite field electroplating device, and the production of wire saws for silicon wafer cutting experiments.MethodsThe electroplating mixture spirals in the same direction around the baseline, which can improve the consistency of diamond particle concentration around the baseline circumference and enhance the uniformity of the mixed solution stirring. …”
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856
Enhanced structural damage detection through combined MODWT and FFT for power spectral density separation in beam vibration analysis
Published 2025-09-01“…This study presents a method to separate vibration modes into distinct components, simplifying structural vibration analysis. …”
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857
Free Vibrations and Nonlinear Responses for a Cantilever Honeycomb Sandwich Plate
Published 2018-01-01“…Based on the Rayleigh–Ritz method, some modes of natural frequencies for the cantilever honeycomb sandwich plate are obtained. …”
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858
Transcranial Doppler microemboli and acute brain injury in extracorporeal membrane oxygenation: A prospective observational studyCentral MessagePerspective
Published 2022-10-01“…Transcranial Doppler (TCD) allows real-time characterization of regional cerebral hemodynamics, but limited data exist on the interpretation of microembolic signals (MES) in ECMO. Methods: This prospective cohort study was conducted at a single tertiary care center, November 2017 through February 2022, and included all adult patients receiving venoarterial (VA) and venovenous (VV) ECMO undergoing TCD examinations, which all included MES monitoring. …”
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859
Study on anti-collapse performance of CFST structures under collision load in different cases.
Published 2025-01-01“…Comparing the two working conditions with the direct simulation method (DS) and the alternate path method (AP), the reliability of AP method in evaluating the internal force of the remaining structure under impact load is insufficient, and it is unsafe to judge the collapse degree of the structure. …”
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860
Harnessing Raman spectroscopy and multimodal imaging of cartilage for osteoarthritis diagnosis
Published 2024-12-01“…Abstract Osteoarthritis (OA) is a complex disease of cartilage characterised by joint pain, functional limitation, and reduced quality of life with affected joint movement leading to pain and limited mobility. Current methods to diagnose OA are predominantly limited to X-ray, MRI and invasive joint fluid analysis, all of which lack chemical or molecular specificity and are limited to detection of the disease at later stages. …”
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