Family caregivers’ perceptions and challenges in the care of pressure injuries in daily life: a qualitative study by Yi Chen, Tingting Cai, Ping Le, Lijuan Zhang, Yunxia Chen, Linzhu Wu, Kejian Chen, Changrong Yuan, Yan Lu

“…Notably, caregivers frequently struggle to recognize early warning signs of deterioration, leading to missed opportunities for timely intervention. These findings highlight key discrepancies between actual care and clinical expectations. …”
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Plasma NLRC4 and NLRP3 as potential diagnostic biomarkers for non-small cell lung cancer in pulmonary tuberculosis by Mengting Xiong, Shuanshuan Xie, Chenlei Cai, Jun Ma, Jiawei Yang, Yunlu Gu, Jian Ni, Haiyan Cui, Wei Sha

“…Abstract Background Differentiating NSCLC from PTB remains a clinical challenge, especially when new or enlarging lung lesions appear during tuberculosis treatment. This often leads to missed surgical opportunities and delays in cancer management. …”
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The effects of a brand-specific, hemp-derived cannabidiol product on physiological, biochemical, and psychometric outcomes in healthy adults: a double-blind, randomized clinical tr... by Gianna F. Mastrofini, Bridget A. McFadden, Alexa J. Chandler, Blaine S. Lints, Harry P. Cintineo, Nathaniel D. Rhoades, Caroline S. Vincenty, Sten O. Stray-Gundersen, Abbi D. Lane, Shawn M. Arent

“…“Vigor-activity” decreased across the intervention, which may be a confounding effect of the academic semester. …”
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Measurable residual disease in hematologic malignancies: a biomarker in search of a standard by Namrata S. Chandhok, Mikkael A. Sekeres

“…Across diseases, does intervention at an MRD-positive state improve survival more than waiting for morphologic or radiographic relapse? …”
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Outcome of universal newborn hearing screening conducted in three referral hospitals in Cameroon by Emmanuel Choffor-Nchinda, Naiza Monono, Audrey Mawota, Antoine Bola, Roger Christian Meva’a Biouélé, Adele-Rose Ngo Nyeki

“…Without UNHS, many children with CHI are probably missed at the time when they would benefit most from treatment. …”
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Generation Victoria (GenV): protocol for a longitudinal birth cohort of Victorian children and their parents by Elizabeth K. Hughes, William Siero, Alisha Gülenç, Susan A. Clifford, Tony Frugier, Simon M. Hall, Jatender Mohal, Kathryn North, Natasha Zaritski, Sharon Goldfeld, Richard Saffery, Melissa Wake

“…Australia’s Generation Victoria (GenV) cohorts are designed for multi-pronged discovery (what could improve outcomes?) and intervention research (what actually works, how much and for whom?). …”
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Effects of Mentha on blood pressure: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials by Faezeh Nematolahi, Abbas Mohtashamian, Ghazal Kaveh, Nasrin Sharifi, Alireza Milajerdi

“…Also, a “snowball search” was applied to include other relevant trials that may have been missed. A random-effects model was used for quantitative data synthesis, with weight mean difference (WMD) and 95% confidence intervals (CI). …”
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Participant Adherence in Repeated-Dose Clinical Studies Using Video-Based Observation: Retrospective Data Analysis by Seunghoon Han, Jihong Song, Sungpil Han, Suein Choi, Jonghyuk Lim, Byeong Yeob Oh, Dongoh Shin

“…The use of various alarm features and appropriate intervention by the investigator or observer was identified as a way to minimize adherence deterioration. …”
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Pediatric cervical spine clearance: a 10-year evaluation of X-ray in evaluable patients at a level 1 pediatric trauma center by Jing Wang, William Starr, Stephanie Iantorno, Richard Eldredge, Rajiv Iyer, Karch Smith, Natalya McNamara, Kezlyn Larsen, Stephen Fenton, Robert Swendiman, Katie Russell

“…Five patients who received additional imaging were treated with a cervical collar, but no operative intervention.Conclusions In this cohort, screening XR had a sensitivity of 100% for clinically significant c-spine injuries. …”
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Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study. by Andrew Sommerlad, Séverine Sabia, Archana Singh-Manoux, Glyn Lewis, Gill Livingston

“…Future intervention studies should seek to examine whether improving social contact frequency is feasible, acceptable, and efficacious in changing cognitive outcomes.…”
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Detection rate and treatment gap for atrial fibrillation identified through screening in community health centers in China (AF-CATCH): A prospective multicenter study. by Yi Chen, Qi-Fang Huang, Chang-Sheng Sheng, Wei Zhang, Shuai Shao, Dian Wang, Yi-Bang Cheng, Ying Wang, Qian-Hui Guo, Dong-Yan Zhang, Yan Li, Nicole Lowres, Ben Freedman, Ji-Guang Wang

“…We aimed to investigate the prevalence of unknown and untreated AF in community residents (≥65 years old) and to determine whether an education intervention could improve oral anticoagulant (OAC) prescription.…”
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Effectiveness of a reduced dose of ready-to-use therapeutic food in community-based management of severe acute malnutrition: A non-inferiority randomized controlled trial in the De... by Julien Ntaongo Alendi, Cécile Salpeteur, Steve Botomba, Alemayehu Argaw, Victor Nikièma, Jean-Baptiste Mayavanga, Benjamin Guesdon, Marie Petry, Uwimana Sebinwa, Sophie Bruneau, Aimée Mupuala Masaya, Florence Mbiya Muadi, Samuel Mampunza Ma Miezi, Marie-Claire Muyer

“…Children were randomly assigned to either a control group receiving the standard WHO (World Health Organization) RUTF dose at the time or an intervention group receiving a reduced RUTF dose starting from the third week of treatment. …”
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Typology of “Displased criticism” in scientific pedagogical dialogues as a methodological phenomenon by A. V. Korzhuev, N. V. Golovina, N. A. Kontarov, Yu. B. Ikrennikova

“…Therefore, the authors of the present research considered it necessary to carry out methodological “intervention” in the problem of correct dialogue in pedagogy.   …”
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Management of possible serious bacterial infection in young infants where referral is not possible in the context of existing health system structure in Ibadan, South-west Nigeria. by Adejumoke Idowu Ayede, Oluwakemi Oluwafunmi Ashubu, Kayode Raphael Fowobaje, Samira Aboubaker, Yasir Bin Nisar, Shamim Ahmad Qazi, Rajiv Bahl, Adegoke Gbadegesin Falade

“…Assuming 30% of births were missed due to temporary migration to maternal homes for delivery care and approximately 45% cases came from outside the catchment area due to free availability of medicines, the treatment coverage was 97.3% (668 cases/6861 expected births) with an expected 10% PSBI prevalence within the first 2 months of life. …”
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Precision versus Protocol: A Cross-sectional Analysis of Gastric Biopsy Techniques in Detecting Premalignant Lesions by Mrunal Kesari, Yoganand Patil, V Kalaivanan, Indranil Bhattacharya

“…The early and accurate detection of these lesions is critical for effective intervention and improved patient outcomes. Aim: To study the Sydney protocol and targeted single-site biopsy in detecting premalignant gastric lesions, identifying the most reliable method for early diagnosis. …”
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Therapeutic Effects of Topical Traditional Chinese Medicine on Upper Extremity Fractures by Lin WY, Lu CA, Chang CW, Yeh YC

“…Non-parametric tests were used for analysis.Results: A total of 24 participants were equally randomized into four study groups, achieving 100% adherence, with no missed doses or clinic visits [retention rate: 100%; drug compliance rate: 100%]. …”
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For girls and women (4GW) HPV RCT protocol: a crowdsourced, pragmatic stepped-wedge cluster randomized trial to improve uptake of HPV vaccination and screening among mother-daughte... by Juliet Iwelunmor, Agatha E. Wapmuk, Ekenechukwu Kokelu, Temitope Ojo, Olufunto Olusanya, Titilola Gbaja-Biamila, Folahanmi T. Akinsolu, Adesola Z. Musa, Hong Xian, Olunike R. Abodunrin, Peter Kalulu, Angel Obiorah, Maria Afadapa, Nkiruka Obodoechina, Ucheoma Nwaozuru, Onyeka Anikamadu, Jennifer Smith, Benedict N. Azuogu, Kayode Ajenifuja, Mengmeng Jia, Assanatou Bamogo, Abdulhammed Babatunde, Jason J. Ong, Lei Zhang, Zhuoru Zou, Collins O. Airhihenbuwa, Joseph D. Tucker, Oliver C. Ezechi

“…Discussion This study is a unique dyadic intervention focused on both girls and their mothers or female caregivers to drive cervical cancer control in Africa. …”
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BioImpedance Spectroscopy to maintain Renal Output: the BISTRO randomised controlled trial by Simon J Davies, David Coyle, Elizabeth Lindley, David Keane, John Belcher, Fergus Caskey, Indranil Dasgupta, Andrew Davenport, Ken Farrington, Sandip Mitra, Paula Ormandy, Martin Wilkie, Jamie MacDonald, Mandana Zanganeh, Lazaros Andronis, Ivonne Solis-Trapala, Julius Sim

“…Probability of the intervention being cost-effective was 76% and 83% at the willingness-to-pay thresholds of £20,000 and £30,000 per quality-adjusted life-year gained, respectively. …”
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Speeding up drug susceptibility testing in Mycobacterium tuberculosis using RNA biomarkersResearch in context by Amandine Sury, Margo Maex, Alain Baulard, Roby P. Bhattacharyya, Stéphanie Depickère, Deborah T. Hung, Paul Cos, Fadel Sayes, Wafa Frigui, Roland Brosch, Vanessa Mathys, Elizabeth M. Streicher, Frederik De Keersmaeker, Leen Rigouts, Pieter-Jan Ceyssens, An Van den Bossche

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