Divergent impact of long-term anthropogenic nitrogen inputs on global particulate and mineral-associated organic carbon by Xinhao Peng, Wei Wei, Shuli Niu, Yuanyuan Huang, Liding Chen

“…Anthropogenic nitrogen inputs increase the levels of reactive nitrogen, significantly influencing SOC dynamics. Given the complexity of SOC, it remains unclear how its key components—particulate organic carbon (POC) and mineral-associated organic carbon (MAOC)—respond to nitrogen addition over time, due to their fundamental differences in formation, persistence, and functions. …”
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Genomic hotspots for adaptation: the population genetics of Müllerian mimicry in the Heliconius melpomene clade. by Simon W Baxter, Nicola J Nadeau, Luana S Maroja, Paul Wilkinson, Brian A Counterman, Anna Dawson, Margarita Beltran, Silvia Perez-Espona, Nicola Chamberlain, Laura Ferguson, Richard Clark, Claire Davidson, Rebecca Glithero, James Mallet, W Owen McMillan, Marcus Kronforst, Mathieu Joron, Richard H Ffrench-Constant, Chris D Jiggins

“…In contrast, at HmB a single peak of association indicates the likely position of functional sites at three genes, encoding a kinesin, a G-protein coupled receptor, and an mRNA splicing factor. …”
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Genome-Wide Identification of the GPAT Family in <i>Medicago sativa</i> L. and Expression Profiling Under Abiotic Stress by Jianzhi Ma, Mingyang Du, Huiyan Xiong, Ruijun Duan

“…It was also ascertained that these <i>GPAT</i> genes might assume a crucial role in salt and drought stress. …”
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Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy. by Keiko Miyadera, Ian Brierley, Jesús Aguirre-Hernández, Cathryn S Mellersh, David R Sargan

“…<h4>Results and significance</h4>We observed a low rate of use of alternative start codons having potential to allow forms of transcript not including the insertion, with the possibility of encoding truncated functional RPGRIP1 protein isoforms. Complex alternative splicing was observed, but did not increase this potential. …”
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Quantifying conformational heterogeneity of 3D genome organization in fruit fly. by Samira Mali, Igor S Tolokh, Erik Cross, Alexey V Onufriev

“…Within our computational approach, depletion of nuclear lamins leads to increased structural heterogeneity at nearly all genomic separations, with the potential implication that cell functions that depend on chromatin structure might be more variable within lamins depleted nuclei compared to the wild type.…”
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Adsorption Properties of Fishbone and Fishbone-Derived Biochar for Cadmium in Aqueous Solution by Nan Pei, Wenwen Luo, Qingqing Huang, Yuebing Sun

“…Moreover, the potential adsorption mechanisms of Cd²⁺ on FBM and fishbone-derived biochar might be related to pore filling, ion exchange, complexation with oxygen functional groups, and precipitation with the minerals on the biochar surface. …”
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System theory as a tool for searching for new scientific directions and problematic aspects of pharmacy in the context of social responsibility by N. O. Tkachenko, O. A. Ryzhov, B. Р. Hromovyk

“…Through the prism of ST, the pharmaceutical sector of the Ukrainian healthcare system can be represented as a complex open system. It performs some basic and auxiliary functions. …”
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Environmental drivers of the resistome across the Baltic Sea by Joeselle M. Serrana, Francisco J. A. Nascimento, Benoît Dessirier, Elias Broman, Malte Posselt

“…Furthermore, our analysis suggests that microbial community composition and mobile genetic elements might be crucial in shaping ARG diversity and composition. …”
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Investigating the impact of synonymous gene recoding on a recombinantly expressed monoclonal antibody under different process parameters by Nayiri M. Kaissarian, Stephanie L. Sandefur, Arnab Ghosh, Upendra K. Katneni, Wendy Walton, Christopher C. Frye, Anton A. Komar, Chava Kimchi‐Sarfaty

“…To investigate how changing mRNA sequence composition under different protein production parameters might affect the quality of recombinantly produced mAbs, we performed a comprehensive and systematic study assessing impact of synonymous gene recoding (commonly referred to as codon optimization) strategies in the context of varied cell culture parameters on product quality, biochemical and functional characteristics. …”
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PO48 | Thrombotic risk evaluation and thrombophilia testing in beta-thalassemia patients: a retrospective cohort analysis from a reference regional center

“…Nineteen had complete screening (including both functional and genetic testing), while 18/65 and 28/65 patients had partial genetic and functional screening, respectively (Table 1). …”
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Surgical vs. Non-Surgical Management of Mandibular Condyle Fractures in Adolescent by Abdurrahman Adirhesa, Carolina Cita Brilliani, Fredy Mardiyantoro

“…Non-surgical methods, including functional appliances and mouth-opening exercises, showed promising results, with improved mouth opening and condylar remodeling. …”
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DATA MINING IN RELATIONAL SYSTEMS by Valentin Filatov, Valerii Semenets, Oleg Zolotukhin

“…The search for association rules is far from a trivial task, as it might seem at first glance. One of the problems is the algorithmic complexity of finding frequently occurring itemsets, since as the number of items grows, the number of potential itemsets grows exponentially.…”
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Orientation reversal and the Chern-Simons natural boundary by Griffen Adams, Ovidiu Costin, Gerald V. Dunne, Sergei Gukov, Oğuz Öner

“…Our new resurgent perspective leads to a practical numerical algorithm that generates q-series which are dual to unary q-series composed of false theta functions. Until recently, these duals were only known in a limited number of cases, essentially based on Ramanujan’s mock theta functions, and the common belief was that the duals might not even exist in the general case. …”
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Streamlining cVEP Paradigms: Effects of a Minimized Electrode Montage on Brain–Computer Interface Performance by Milán András Fodor, Atilla Cantürk, Gernot Heisenberg, Ivan Volosyak

“…Three experimental conditions were tested: a baseline 16-electrode configuration, a reduced 6-electrode setup without retraining, and a reduced 6-electrode setup with retraining. (3) Results: Our results indicate that, on average, performance declines with fewer electrodes; nonetheless, retraining restored near-baseline mean Information Transfer Rate (ITR) and accuracy for those participants for whom the system remained functional. The results reveal that for a substantial number of participants, the classification pipeline fails after electrode removal, highlighting individual differences in the cVEP response characteristics or inherent limitations of the classification approach. (4) Conclusions: Ultimately, this suggests that minimal cVEP-BCI electrode setups capable of reliably functioning across all users might only be feasible through other, more flexible classification methods that can account for individual differences. …”
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Effects of proteasome inhibitor MG-132 on the parasite Schistosoma mansoni. by Enyara R Morais, Katia C Oliveira, Renato G de Paula, Alice M M Ornelas, Érika B C Moreira, Fernanda Rafacho Badoco, Lizandra G Magalhães, Sergio Verjovski-Almeida, Vanderlei Rodrigues

“…Proteasome is a proteolytic complex responsible for intracellular protein turnover in eukaryotes, archaea and in some actinobacteria species. …”
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Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D. by Sreeram V Ramagopalan, Narelle J Maugeri, Lahiru Handunnetthi, Matthew R Lincoln, Sarah-Michelle Orton, David A Dyment, Gabriele C Deluca, Blanca M Herrera, Michael J Chao, A Dessa Sadovnick, George C Ebers, Julian C Knight

“…Multiple sclerosis (MS) is a complex trait in which allelic variation in the MHC class II region exerts the single strongest effect on genetic risk. …”
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Unravelling the nexus of stroke and dementia: Deciphering the role of secondary neurodegeneration in orchestrating cognitive decline by Shannon M. Stuckey, Rebecca J. Hood, Lin Kooi Ong, Isabella M. Bilecki, Lyndsey E. Collins‐Praino, Renée J. Turner

“…Degeneration in these sites is thought to arise due to functional diaschisis with the infarct core; however, observation of SND pathology in multiple regions without direct connectivity to the stroke infarct suggests that the degeneration in these regions is likely more complex. …”
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MicroRNA-32-5p promotes the proliferation and metastasis of gastric cancer cells by Chao Sun, Lai-gang Huang, Bing Leng, Yanting Guo, Chen Chen, Ruijie Lv, Yan Dong, Tian-tian Gao, De-qing Sun

“…Furthermore, we found that DSC2 suppressed the transcription of Cyclin B1, and induced G2/M phase arrest through inhibiting the complex of β-catenin/TCF4 in nucleus. We concluded that miR-32-5p negatively regulated the DSC2 expression, might be a potential therapeutic targeting of cancers, most especially in GC.…”
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LGBT Actors, Ritual and Martial Arts Groups, and State-Building in Post-Conflict Timor-Leste by Lili Chen, Laura Sjoberg

“…We conclude by arguing that openness to seeing more complexities in gender and sexuality within RAGs and MAGs can also show more complexities in their activities, including but not limited to community-building and state-building. …”
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Genome-wide association studies of the fatty acid composition of Korean native chicken breast meat by Jean Pierre Munyaneza, Minjun Kim, Eunjin Cho, Aera Jang, Hyo Jun Choo, Jun Heon Lee

“…Interestingly, two candidate genes (GPNMB and SFRP1) were reported to regulate the expression of genes known to be involved in fatty acid synthesis, such as the FASN, ACACA, ACLY, ELOVL, and SCD genes. Identification of functional candidate genes for fatty acid profiles might facilitate the selection and breeding of chickens with desirable and healthier fatty acids. …”
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