Mariner Transposons Contain a Silencer: Possible Role of the Polycomb Repressive Complex 2. by Solenne Bire, Sophie Casteret, Benoît Piégu, Linda Beauclair, Nathalie Moiré, Peter Arensbuger, Yves Bigot

“…Here, we describe a silencer situated in the last 300 bp of the Mos1 transposase open reading frame (ORF) which functions in vertebrate and arthropod cells. Functional silencers are also found at similar locations within three other animal mariner elements, i.e. …”
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Plant tolerance to drought stress: Complexity and mechanism across physiological, molecular and biochemical scales by Asfa Batool, Dong-Xia Yue, Yun-Li Xiao, Shi-Sheng Li, Hai-Xia Duan, Zeeshan Haq, Khalil Ahmed, Ling Zhao, Li Zhu, Y.C. Xiong

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The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication. by Erika Shor, Christopher L Warren, Joshua Tietjen, Zhonggang Hou, Ulrika Müller, Ilaria Alborelli, Florence H Gohard, Adrian I Yemm, Lev Borisov, James R Broach, Michael Weinreich, Conrad A Nieduszynski, Aseem Z Ansari, Catherine A Fox

“…Since HMR-E possessed a unique non-replication function, we reasoned that other tight sites might reveal novel functions for ORC on chromosomes. …”
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Clinical and functional remission assessment in patients with recurrent depression by N. N. Petrova

“…Whether therapy with different antidepressants might achieve functional remission was studied using agomelatine as an example. …”
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On the structure of species-function participation in multilayer ecological networks by Sandra Hervías-Parejo, Mar Cuevas-Blanco, Lucas Lacasa, Anna Traveset, Isabel Donoso, Ruben Heleno, Manuel Nogales, Susana Rodríguez-Echeverría, Carlos J. Melián, Victor M. Eguíluz

“…Yet, traditional assessments of ecological complexity typically focus on species-species interactions that mediate a particular function (e.g., pollination), overlooking both the synergistic effect that multiple functions might develop as well as the resulting species-function participation patterns that emerge in ecosystems that harbor multiple ecological functions. …”
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Statistical Analysis of Tract-Tracing Experiments Demonstrates a Dense, Complex Cortical Network in the Mouse. by Rolf J F Ypma, Edward T Bullmore

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Unveiling complex brain dynamics during movie viewing via deep recurrent autoencoder model by Kexin Wang, Limei Song, Zhaowei Li, Liting Wang, Xiaowei He, Yudan Ren, Jinglei Lv

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Perspective: How complex in vitro models are addressing the challenges of predicting drug-induced liver injury by K. Taylor, R. Ram, R. Ram, L. Ewart, C. Goldring, G. Russomanno, G. P. Aithal, T. Kostrzewski, C. Bauch, J. M. Wilkinson, J. M. Wilkinson, S. Modi, J. G. Kenna, J. G. Kenna, J. Bailey, J. Bailey

“…Predicting which drugs might have the potential to cause drug-induced liver injury (DILI) is highly complex and the current methods, 2D cell-based models and animal tests, are not sensitive enough to prevent some costly failures in clinical trials or to avoid all patient safety concerns for DILI post-market. …”
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Raman-based sorting of microbial cells to link functions to their genes by Kang Soo Lee, Michael Wagner, Roman Stocker

“…By combining stable isotope probing, optical tweezers, Raman microspectroscopy, and microfluidics, the platform performs automated Raman-based sorting of taxa from within a complex community in terms of their functional properties. …”
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Extensive microbial and functional diversity within the chicken cecal microbiome. by Martin J Sergeant, Chrystala Constantinidou, Tristan A Cogan, Michael R Bedford, Charles W Penn, Mark J Pallen

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A comprehensive functional classification of cleft hand: The DAST concept by Alok Sharma, Namita Sharma

“…Results and Conclusions: The necessity to include and to assess all determinants of function and complexity in these hands to standardise the choice of management, gave rise to the DAST system of classification; an acronym for all the morphological determinants of the anomaly (D = Digits missing, A = Associated anomalies in the hand, S = Site of cleft, T = Functional state of the Thumb). …”
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Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins. by Alistair Bailey, Andy van Hateren, Tim Elliott, Jörn M Werner

“…Major histocompatibility complex class I molecules (MHC I) present peptides to cytotoxic T-cells at the surface of almost all nucleated cells. …”
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How (and why) languages became more complex as we evolved more prosocial: the human self-domestication view by Antonio Benítez-Burraco

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Increased maternal genome dosage bypasses the requirement of the FIS polycomb repressive complex 2 in Arabidopsis seed development. by David Kradolfer, Lars Hennig, Claudia Köhler

“…Here, we show that the functional requirement of the FIS-PRC2 can be bypassed by increasing the ratio of maternal to paternal genomes in the endosperm, suggesting that the main functional requirement of the FIS-PRC2 is to balance parental genome contributions and to reduce genetic conflict. …”
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STUDY OF CRUSTAL STRUCTURE OF THE FLORES ISLAND USING RECEIVER FUNCTION METHOD by Nanda Dewi Pamungkas Siwi, Ramadhan Priadi, Puji Ariyanto

“…Formed as a consequence of very complex tectonic setting that might cause relatively high level of seismic in the region. …”
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The potential functions of HvDJ genes in regulating salt tolerance in barley by Yunfeng Xu, Haoran Sun, Ling Shen, Boyan Wan, Lijun Liu, Guoping Zhang, Guoping Zhang, Guoping Zhang, Qiufang Shen, Qiufang Shen, Qiufang Shen

“…Protein–protein interaction analysis indicated that HvDJA09 and HvDJA05 play core roles in the complex regulatory network. Taken together, the current study provides valuable information for a deeper understanding of the function of HvDJs in regulating salt stress tolerance in barley.…”
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Influence of Uric Acid on Vascular and Cognitive Functions: Evidence for an Ambivalent Relationship by Francesco Baratta, Federica Moscucci, Evaristo Ettorre, Raffaella Bocale, Arrigo F. G. Cicero, Pietro Cirillo, Federica Fogacci, Ilaria Lospinuso, Carmine Savoia, Alessandro Mengozzi, Agostino Virdis, Claudio Borghi, Giovambattista Desideri

“…In addition, some studies support the hypothesis that elevated uric acid levels could reduce the risk of Alzheimer’s disease, slow down the decline of cognition, and delay the progression of Alzheimer’s disease, while other evidence achieves opposite positions. These discrepancies might reflect a biological ambivalence for uric acid depending on a very complex interplay of factors that include its concentrations achieved in biological fluids, the nature, and concentration of free radicals, the presence and concentration of other antioxidant molecules, potentially responsible for bi-directional effects of uric acid on brain health/functioning. …”
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Managing functional neurological disorder: treatment recommendations for health professionals in Australia by Alexander Lehn, Megan Broughton, Vince Cheah, Tjerk J Lagrand, Jessica Davis, David Palmer, Dharsha Petrie, Cindy Bradbury, Rianna Guest, Alana Schuurs, Jacinta Lewis, Rebecca Madden, Julia McLeod, Rodney Marsh, Christine Slade, Tjerk Lagrand

“…Functional Neurological Disorder (FND) can present significant management challenges due to its sometimes-complex presentation and the historical stigma attached to this diagnosis. …”
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EEG microstates: Functional significance and short-term test-retest reliability by Elena Antonova, Martin Holding, Ho Chak Suen, Alex Sumich, Reinoud Maex, Chrystopher Nehaniv

“…This might be more fruitfully achieved by looking at their complex syntax beyond pairwise transitions. …”
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Target organs in patients with post-infarction chronic heart failure: dynamics during complex therapy including beta-adrenoblockers by I. P. Rubesh, L. A. Nekrutenko, A. V. Tuev, Yu. V. Larina, A. V. Agafonov

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