Combined fMRI and eye-tracking evidence on the neural processing of visual ambiguity in photographic aesthetics by Maria Arioli, Nicola Canessa, Alessandra Gargiulo, Matteo Zardin, Andrea Falini, Alberto Sanna

“…Task-by-stimulus type interaction analyses showed that evaluating ambiguous stimuli was specifically associated with stronger fixation-related activity in the left medial prefrontal cortex, as well as decreased connectivity from this region to its right-hemispheric homologue, possibly supporting in-depth visuospatial analyses of complex visual images. These findings pave the way for future studies addressing the role of visual ambiguity in aesthetic appreciation, as well as the factors that might ease vs. hamper its processing and resolution, and their neural correlates.…”
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Human Development XIII: The Connection Between the Structure of the Overtone System and the Tone Language of Music. Some Implications for Our Understanding of the Human Brain by Søren Ventegodt, Tyge Dahl Hermansen, Isack Kandel, Joav Merrick

“…The functioning brain behaves like one highly-structured, coherent, informational field. …”
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Kinesthetic illusions induced by muscle tendon vibration: The orientation of the vibration motor as a new methodological factor? by Lydiane Lauzier, Jacques Abboud, François Nougarou, Louis-David Beaulieu

“…Distoproximal rotation was more effective to elicit the expected illusions of wrist extension, compared to the lateromedial orientation that more often caused complex and variable perceptions of movement. Distoproximal rotation should thus be preferred if clear and reproducible perceptions are required and lateromedial might serve as a way of creating illusions more akin to everyday functional movements. …”
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Bagasse minority pathway expression: Real time study of GH2 β-mannosidases from bacteroidetes. by Tatiane Fernanda Leonel, Elisângela Soares Gomes Pepe, Tereza Cristina Luque Castellane, Juliana da Silva Vantini, Michelli Inácio Gonçalves Funnicelli, Eliana Gertrudes de Macedo Lemos

“…The degree of novelty-as demonstrated by the low identity with previously characterized enzymes; the remarkable capability to grow in different substrates; mannanase activity, evidenced by the release of residual oligosaccharides in the cultivation with galactomannan (HPLC-RID, 12.3 mMol); associated to the ability of mannanases expression in a low concentration of inductor conditions (sugarcane bagasse, 0.2%) indicate the high potential for the application of CB10 as a source of enzymes in the production of oligosaccharides from biomass. This capacity might prove to be very valuable for the biorefinery process of pre-biotic precursors and other functional oligosaccharides focused on the food and pharmaceutical industries.…”
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Who understands and how? – exploring nurses’ perceptions of the readability and usability of instructions written by hospital pharmacists by Henri Satokangas, Kirsi Kvarnström, Hanna M. Tolonen

“…Results The interviewed nurses (n = 9) consistently found the instructions somewhat challenging, primarily due to their length, complex structure and limited accessibility. While the interviewees stated that the instructions did not present personal difficulties, they expressed concern that other staff in the ward might struggle with the instructions. …”
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Bioinformatics analysis of lncRNA and mRNA differentially expressed in patients with cervical cancer by Xiaohua An, Xiaohua An, Xiaoxue Huang, Qiujie Yu, Qiujie Yu, Yiyue Tang, Yan Wang, Yan Wang, Huasu Chen, Huasu Chen, Yafei Zhang, Yafei Zhang, Qianhao Huang, Qianhao Huang, Yudi Rao, Yudi Rao, Guomei Hu, He Zha

“…Further analysis indicated that the 20 antisense lncRNAs with the most remarkable differences might exert biological functions by influencing their corresponding mRNAs. …”
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Wisdom of the Established Pattern by Joel Janhonen

“…The wisdom of our intuition might not reveal itself case by case – rather it resides in its broad undefined influence over humanity. …”
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Assessment of Classical Force-Fields for Graphene Mechanics by Zhiwei Ma, Yongkang Tan, Xintian Cai, Xue Chen, Tan Shi, Jianfeng Jin, Yifang Ouyang, Qing Peng

“…Molecular dynamics simulation is a well-established and useful tool for investigating graphene’s atomic structure and dynamic behavior at the nanoscale without requiring expensive and complex experiments. The accuracy of the molecular dynamics simulation depends on the potential functions. …”
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Modal verbs in Indonesian and Malaysian English textbooks for secondary schools: A corpus-driven study by Ikmi Nur Oktavianti, Noor Raha Mohd Radzuan, Bambang Widi Pratolo, Surono Surono, Tri Rina Budiwati, Shifak Aisyah

“…However, modal verbs are complex grammatical units since they have multiple functions and meanings. …”
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Transcriptome Analysis of Large to Giant Congenital Melanocytic Nevus Reveals Cell Cycle Arrest and Immune Evasion: Identifying Potential Targets for Treatment by Boxuan Wei, Jieyu Gu, Ran Duan, Bowen Gao, Min Wu, Shengliang Zhou, Xiaolu Huang, Feng Xie

“…Antiapoptotic activity and immune evasion might explain how such heterogeneous cells have avoided elimination. …”
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mRNA Trafficking in the Nervous System: A Key Mechanism of the Involvement of Activity-Regulated Cytoskeleton-Associated Protein (Arc) in Synaptic Plasticity by Michal Fila, Laura Diaz, Joanna Szczepanska, Elzbieta Pawlowska, Janusz Blasiak

“…The structure of Arc is similar to the viral GAG (group-specific antigen) protein, and phylogenic analysis suggests that Arc may originate from the family of Ty3/Gypsy retrotransposons. Therefore, Arc might evolve through “domestication” of retroviruses. …”
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De novo characterization of microRNAs in oriental fruit moth Grapholita molesta and selection of reference genes for normalization of microRNA expression. by Xiu Wang, Yisong Li, Jing Zhang, Qingwen Zhang, Xiaoxia Liu, Zhen Li

“…MicroRNAs (miRNAs) are a group of endogenous non-coding small RNAs that have critical regulatory functions in almost all known biological processes at the post-transcriptional level in a variety of organisms. …”
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Genomics and proteomics of the liver fluke <em>Opisthorchis felineus</em> by V. A. Mordvinov, N. I. Ershov, O. G. Zaparina, M. Y. Pakharukova

“…Data on the O. felineus genomics and proteomics provide first insights into the structural and functional organization of the genome of this parasitic flatworm with a complex life cycle as well as provide a significant contribution to our understanding of “host-parasite” interaction and evolution of this group of parasitic flatworms.…”
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Investigating the dual role of mitochondrial and nuclear genome variants in pediatric cardiomyopathies by M. Arda Temena, Ebru Erzurumluoglu Gokalp, Ezgi Susam, Duygu Cinar, Hikmet Kiztanir, Pelin Kosger, Beyhan Durak Aras, Sevilhan Artan, Oguz Cilingir

“…Specifically, a variant in FOXRED1, encoding FAD-dependent oxidoreductase domain-containing protein-1 which functions in mitochondrial complex I stability, and another variant in cytochrome c oxidase-I, MT-CO1, crucial for aerobic metabolism, were identified in two siblings with hypertrophic cardiomyopathy. …”
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Approaches used to prevent and reduce the use of restrictive practices on adults with learning disabilities: a realist review by Joy Duxbury, Alina Haines-Delmont, John Baker, Peter Baker, Gary Bourlet, Elaine Craig, James Ridley, Rachel Whyte, Beth Morrison, Michaela Thomson, Anthony Tsang, Tella Lantta

“…This overarching programme theory indicates that while there are interventions that might work in mental health settings (‘what works?’)…”
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Modulation of Cardiac Contractility – a New Method in the Treatment of Heart Failure by A. A. Petrukhina, S. N. Tereshchenko, I. V. Zhirov

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Antagonist actions of CMK-1/CaMKI and TAX-6/calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli by Martina Rudgalvyte, Zehan Hu, Dieter Kressler, Jörn Dengjel, Dominique A Glauser

“…Since CMK-1 and TAX-6 act in distinct cell types, the phosphorylation observed in vitro might not directly underlie the behavioral phenotype. …”
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Different Stability and Proteasome-Mediated Degradation Rate of SMN Protein Isoforms. by Denise Locatelli, Mineko Terao, Mami Kurosaki, Maria Clara Zanellati, Daniela Rita Pletto, Adele Finardi, Francesca Colciaghi, Enrico Garattini, Giorgio Stefano Battaglia

“…However, to what extent the impairment of these two SMN functions contributes to SMA pathogenesis remains unknown. …”
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Vaccinia virus protein C6 is a virulence factor that binds TBK-1 adaptor proteins and inhibits activation of IRF3 and IRF7. by Leonie Unterholzner, Rebecca P Sumner, Marcin Baran, Hongwei Ren, Daniel S Mansur, Nollaig M Bourke, Felix Randow, Geoffrey L Smith, Andrew G Bowie

“…Thus C6 contributes to VACV virulence and might do so via the inhibition of PRR-induced activation of IRF3 and IRF7.…”
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Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae. by Takasuke Fukuhara, Tomokazu Tamura, Chikako Ono, Mai Shiokawa, Hiroyuki Mori, Kentaro Uemura, Satomi Yamamoto, Takeshi Kurihara, Toru Okamoto, Ryosuke Suzuki, Kentaro Yoshii, Takeshi Kurosu, Manabu Igarashi, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura

“…These results strongly suggest that the host- and virus-derived secretory glycoproteins have overlapping roles in the viral life cycle of Flaviviridae, especially in the maturation of infectious particles, while Erns and NS1 also participate in replication complex formation and viral entry, respectively. Considering the abundant hepatic expression and liver-specific propagation of these apolipoproteins, HCV might have evolved to utilize them in the formation of infectious particles through deletion of a secretory viral glycoprotein gene.…”
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