High‐order combination effects and biological robustness by Joseph Lehár, Andrew Krueger, Grant Zimmermann, Alexis Borisy

“…Biological systems are also complex, being organized into many functional modules that communicate through interlocking pathways and feedback mechanisms. …”
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Adjusting the timing of inseminations to the time lag on luteolysis alerts results in higher conception in dairy cattle by D. Meuwissen, M.J. Gote, R. Meyermans, S. Janssens, I. Adriaens, B. Aernouts

“…ABSTRACT: Dairy cow fertility is a complex trait that depends on the cow's physiological status, the farm's environmental and management conditions, and their interactions. …”
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Mitochondrial RNA maturation by Zofia M. Chrzanowska-Lightowlers, Robert N. Lightowlers

“…These processes are sometimes driven by the unusual behaviour of the mitochondrial genome from which the RNA is originally transcribed, but in many examples the complex processes that are essential for the production of functional RNA in the organelle, are fascinating and bewildering.…”
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Exploring Therapists’ Approaches to Treating Eating Disorders to Inform User-Centric App Design: Web-Based Interview Study by Pamela Carien Thomas, Pippa Bark, Sarah Rowe

“…Many existing interventions have limited functionality or do not differ much from manual cognitive behavioral therapy (CBT) or self-help books, which may not adequately support the therapeutic process or sustain user engagement. …”
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Multi-omics analyses construct an inflammatory response based prognostic gene signature for cervical cancer and suggest tumor infiltrating monocytes subgroups as key players by Yidong Zhang, Jiawei Zhu, Ke Hu, Jie Qiu, Fuquan Zhang, Fuquan Zhang

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Neural Network Dynamics without Minimizing Energy by Mau-Hsiang Shih, Feng-Sheng Tsai

“…Studies of such neural network systems are typically based on the aspect of energy minimization. However, when the complexity and the dimension of neural network systems go up, the use of energy functions might have its own limitations to study CAM. …”
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Differing evolutionary histories of the ACTN3*R577X polymorphism among the major human geographic groups. by Carlos Eduardo G Amorim, Victor Acuña-Alonzo, Francisco M Salzano, Maria Cátira Bortolini, Tábita Hünemeier

“…It has been proposed that the functional ACTN3*R577X polymorphism might have evolved due to selection in Eurasian human populations. …”
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A custom-made mouthguard reduces head acceleration during soccer heading and prevents acute electrophysiological and cognitive changes in amateur male playersResearch in context by Claire Pitteu, Philippine Lepère, Philippe Poisson, Etienne Guillaud, Emilie Doat, Bertrand Glize, Patrick Dehail, Hélène Cassoudesalle

“…Summary: Background: Repetitive head impacts related to soccer heading might lead to long-term risk of neurodegenerative diseases. …”
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Agreement of glomerular filtration rate estimation equations for chemotherapy dosing in cancer patients at a tertiary referral hospital in Sub-Saharan Africa. by Wubshet Jote Tolossa, Tigist Workneh Leulseged, Abdu Adem, Feyissa Challa, Tirumebet Mezgebu, Ruth S Aytehgeza, Nebiat Adane Mera, Kalsidagn Girma Asfaw, Momina M Ahmed, Kebede H Begna

“…This suggests that current GFR estimation practices in cancer patients might be inaccurate, potentially leading to improper chemotherapy dosing and poorer patient outcomes.…”
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The dual role of microglia in Alzheimer’s disease: from immune regulation to pathological progression by Cong He, Baojiang Chen, Hecai Yang, Xiaoqing Zhou

“…Despite extensive research, the role of microglia in AD remains complex and dual. The aim of this review is to summarize the most recent advances in research regarding the dual role of microglia in AD concerning both immunomodulation and pathological progression by considering mechanisms of activation of microglia, effects on Aβ clearance, tau pathology, and impacts due to genetic variations on microglial functions. …”
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A high throughput method for isolation of plasmatocytes from hemolymph of adult Drosophila. by Mansi Yadav, Jassika Gupta, Debalina Chatterjee, Parul Mittal, Anju Shrivastava, Namita Agrawal

“…Macrophages are essential innate immune system components, exhibiting diverse functions crucial for disease prevention. While much is known about their role in innate immunity, studying their functional versatility remains a challenge. …”
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Urotensin-II: More Than a Mediator for Kidney by Ayşe Balat, Mithat Büyükçelik

“…Recent studies suggest that U-II may have a possible autocrine/paracrine functions in kidney and may be an important target molecule in studying renal pathophysiology. …”
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An Insight on Gut Flora, Colorectal Cancer Mechanism, and Treatment Strategies by Rajendra Kumar, Ashmeen Kaur, Divyanshu Rajput

“…The microbiota in the stomach functions like an actual organ. To maintain gut homeostasis, the digestive tract’s symbiotic relationships with the local microorganisms are crucial. …”
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Beyond awareness: the binding of reflexive mechanisms with the conscious mind: a perspective from default space theory by Ravinder Jerath, Connor Beveridge

“…How do reflexes operate so quickly with so much multimodal information on the environment? How might unconscious processes help reveal the nature of consciousness? …”
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Dynamic regulation of neutrophil immunometabolism by platelet-derived metabolites by Manuel Alejandro Mosso-Pani, Manuel Alejandro Mosso-Pani, Dante Barreda, Ma. Isabel Salazar

“…Additionally, platelets induce metabolic reprogramming in neutrophils, affecting glycolysis and mitochondrial pathways, while also shaping the immune microenvironment by modulating other immune cells, such as T and B cells. Understanding this complex crosstalk between platelets and neutrophils—two of the most abundant cell types in the bloodstream—might reveal new therapeutic opportunities to regulate immune responses in inflammatory and immune-mediated diseases.…”
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A Vehicular Cyber-Physical Framework for Studying the Effects of Multiple Disturbances with Application to Connected Autonomous Vehicles by Mohammed Amir, Marine Lincoln, Ramlal Craig, Muddeen Fasil

“…These systems underpin critical infrastructures (CIs), which require coordination to achieve societal functions. However, the exponential growth of CPSs brings about a new challenge as it relates to the security of such systems and by extension any disturbances which might affect their operation. …”
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Feedback driven autonomous cycles of assembly and disassembly from minimal building blocks by Antara Reja, Sangam Jha, Ashley Sreejan, Sumit Pal, Subhajit Bal, Chetan Gadgil, Dibyendu Das

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EXPRESSION OF GENES ENCODING IMMUNOPROTEASOME SUBUNITS INDUCIBLE BY MACROPHAGES INFECTED WITH M. bovis BGC AND M. Tuberculosis H37RV by S. N. Andreevskaya, T. G. Smirnova, A. V. Timofeev, E. E. Larionova, L. N. Chernousova

“…It was assumed that the inhibited transcription of this subunit, when inoculated with the virulent M. tuberculosis strain, might lead to the blocked assembly of the whole immunoproteasome and to its reduced functional activity. …”
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Throwing Stick to Spear Thrower - Study of Ethnographic Artefacts and Experimentation by Luc Bordes

“…Indeed, some traditional Aboriginal hooked throwing sticks from Coopers Creek might be a trace of a prehistoric throwing stick/spear thrower technological complex which has disappeared to be replaced by true specialised spear throwers from New Guinea, rendering them obsolete. …”
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Nanosensors for Exhaled Breath Condensate: Explored Models, Analytes, and Prospects by Esther Ghanem

“…Nonetheless, conventional EBC screening methods are complex and require high operational costs and expertise. …”
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